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1. 发明申请

US20050008538A1 Compact analyte testing cassette with true positive and negative analyte controls 有权
标题翻译：紧凑的分析物检测盒带有真正的正和负分析物对照
公开(公告)号：US20050008538A1
公开(公告)日：2005-01-13
申请号：US10890544
申请日：2004-07-12
申请人： David Anderson , Hsiaoho Tung , Haipeng Hu , Yuchang Wu
发明人： David Anderson , Hsiaoho Tung , Haipeng Hu , Yuchang Wu
IPC分类号： A61B20060101 , G01N21/86 , G01N31/22 , G01N33/14 , G01N33/558 , G01N33/94
CPC分类号： G01N33/94 , G01N31/22 , G01N33/14 , G01N33/558 , Y10T436/13
摘要： The present disclosure includes but is not limited to an assay or test device, such as an immunological assay device, with positive and negative controls for each analyte of interest. In general, the device has a bi-fold, tri-fold or quarter-fold cassette, each folded side having one or more test strips contained therein. The device is compact and easily used by the worker. The present device is particularly useful in a clinical drug of abuse testing setting, in which the use of internal quality controls is regulated by the USCMS and the College of American Pathologists. In addition, the present device provides the advantages of ease of use, small size and reduced cost compared to other devices currently available on the market.
摘要翻译：本公开包括但不限于对于感兴趣的每种分析物的阳性和阴性对照的测定或测试装置，例如免疫测定装置。通常，该装置具有双折，三折或四分之一折盒，每个折叠侧具有容纳在其中的一个或多个测试条。该设备紧凑，工作人员很容易使用。本设备在滥用测试设置的临床药物中特别有用，其中使用内部质量控制由USCMS和美国病理学家学院进行调节。此外，与目前市场上可获得的其它装置相比，本装置提供了易于使用，小尺寸和降低成本的优点。

2. 发明授权

US07455813B2 Compact analyte testing cassette with true positive and negative analyte controls 有权
标题翻译：紧凑的分析物检测盒带有真正的正和负分析物对照
公开(公告)号：US07455813B2
公开(公告)日：2008-11-25
申请号：US10890544
申请日：2004-07-12
申请人： David Anderson , Hsaioho Edward Tung , Haipeng Hu , Yuchang Wu
发明人： David Anderson , Hsaioho Edward Tung , Haipeng Hu , Yuchang Wu
IPC分类号： G01N33/48
CPC分类号： G01N33/94 , G01N31/22 , G01N33/14 , G01N33/558 , Y10T436/13
摘要： The present disclosure includes but is not limited to an assay or test device, such as an immunological assay device, with positive and negative controls for each analyte of interest. In general, the device has a bi-fold, tri-fold or quarter-fold cassette, each folded side having one or more test strips contained therein. The device is compact and easily used by the worker. The present device is particularly useful in a clinical drug of abuse testing setting, in which the use of internal quality controls is regulated by the USCMS and the College of American Pathologists. In addition, the present device provides the advantages of ease of use, small size and reduced cost compared to other devices currently available on the market.
摘要翻译：本公开包括但不限于对于感兴趣的每种分析物的阳性和阴性对照的测定或测试装置，例如免疫测定装置。通常，该装置具有双折，三折或四分之一折盒，每个折叠侧具有容纳在其中的一个或多个测试条。该设备紧凑，工作人员很容易使用。本设备在滥用测试设置的临床药物中特别有用，其中使用内部质量控制由USCMS和美国病理学家学院进行调节。此外，与目前市场上可获得的其它装置相比，本装置提供了易于使用，小尺寸和降低成本的优点。

3. 发明授权

US07114403B2 Fluid collection and application device and methods of use of same 有权
标题翻译：流体收集和应用装置及其使用方法
公开(公告)号：US07114403B2
公开(公告)日：2006-10-03
申请号：US10855155
申请日：2004-05-27
申请人： Yuchang Wu , Hsiaoho Edward Tung , Huiyan Guo , Fei Gao , Jielin Dai , Haipeng Hu
发明人： Yuchang Wu , Hsiaoho Edward Tung , Huiyan Guo , Fei Gao , Jielin Dai , Haipeng Hu
IPC分类号： G01N1/00
CPC分类号： A61B10/0051 , B01L3/0272 , B01L3/5029
摘要： The present invention is a device for conveniently collecting and storing liquid samples, as well as applying an aliquot of the sample to a test device, such as a lateral flow immunoassay. The present invention comprises an absorbent swab and a dropper container containing an expression means for expressing the collected sample from the swab. After the collected sample has been expressed into the reservoir of the device, the device is capped. The device can be inverted over a test device, the sides of the reservoir squeezed and an aliquot of the sample applied, in a drop-wise manner, to the sample application well of the test device. The present invention is particularly useful for collecting viscous samples, such as saliva or oral fluid, in a drug of abuse testing setting.
摘要翻译：本发明是用于方便地收集和储存液体样品的装置，以及将样品的等分试样施加到测试装置，例如横向流动免疫测定。本发明包括吸收棉签和滴管容器，该容器包含用于从拭子表达所收集的样品的表达装置。收集的样品已经被表达到设备的储存器中之后，装置被盖上。该装置可以在测试装置上倒置，储存器的侧面被挤压，并且样品的等分试样以滴下方式施加到测试装置的样品应用井。本发明特别可用于在滥用试验设备的药物中收集粘性样品，例如唾液或口腔液。

4. 发明授权

US09730646B2 Assay device for testing an analyte in samples 有权
公开(公告)号：US09730646B2
公开(公告)日：2017-08-15
申请号：US14110206
申请日：2012-03-30
申请人： Lin Hu , Haipeng Hu
发明人： Lin Hu , Haipeng Hu
IPC分类号： A61B5/00 , A61B10/00 , A61B5/145 , B01L3/00
CPC分类号： A61B5/7405 , A61B5/14507 , A61B10/0051 , A61B10/007 , B01L3/5023 , B01L3/50825 , B01L2200/143 , B01L2300/042 , B01L2300/0663 , B01L2300/0832 , B01L2400/0433
摘要： This invention provides an assay device for testing an analyte in samples, comprising a chamber with an opening for collecting samples, a test element, and a sound indication structure. The indication structure creates sound by vibrating after the structure deforms and would move back to the original position. The assay device is easy to operate for non-professionals.

5. 发明授权

US08062901B2 Devices and methods for sample collection and analysis 有权
标题翻译：样品收集和分析的设备和方法
公开(公告)号：US08062901B2
公开(公告)日：2011-11-22
申请号：US11119528
申请日：2005-04-30
申请人： Jielin Dai , Haipeng Hu , Feier Liao , Weidong Yu , Shaomin Sun
发明人： Jielin Dai , Haipeng Hu , Feier Liao , Weidong Yu , Shaomin Sun
IPC分类号： G01N33/48
CPC分类号： B01L3/5023 , B01L3/5055 , B01L2200/027 , B01L2300/069 , B01L2300/0825
摘要： The present invention provides devices, methods, and kits for the collection of a solid or semi-solid sample and analysis for the presence, absence, or quantity of an analyte. The invention provides a collection slide having a first card and a second card. The first card has a sample collection area. The first and second cards have orifices allowing the passage of fluid through the sample collection area, and the cards are hingeably connected to each other. The invention also provides an assay device having a housing with a test element, a results window, and a docking area for receiving and engaging the collection slide. In one embodiment the collection slide and device can be used to detect the presence of fecal occult blood (human hemoglobin) in a stool sample. Many other embodiments are described herein.
摘要翻译：本发明提供用于收集固体或半固体样品并分析分析物的存在，不存在或数量的装置，方法和试剂盒。本发明提供一种具有第一卡和第二卡的收集幻灯片。第一张卡片有样品收集区域。第一卡片和第二卡片具有允许流体通过样品收集区域的孔口，并且卡片可铰接地彼此连接。本发明还提供一种具有壳体的测定装置，其具有测试元件，结果窗口和用于接收和接合收集滑块的对接区域。在一个实施方案中，收集载玻片和装置可用于检测粪便样品中粪便潜血（人血红蛋白）的存在。本文描述了许多其它实施例。

6. 发明申请

US20110281344A1 Detection Device 有权
标题翻译：检测装置
公开(公告)号：US20110281344A1
公开(公告)日：2011-11-17
申请号：US13143068
申请日：2010-01-05
申请人： Lijian Gou , Haipeng Hu
发明人： Lijian Gou , Haipeng Hu
IPC分类号： C12M1/34 , G01N33/48
CPC分类号： B01L3/508 , A61B10/007 , A61B10/0096 , A61B2010/0009 , B01L2200/0684 , B01L2200/0689 , B01L2300/047 , B01L2300/048 , B01L2300/0609 , B01L2300/0663 , B01L2300/0825 , B01L2300/126
摘要： A detection device and a detection method are disclosed. The detection device comprises a sample inlet (132) that allows liquid samples flowing from a collection chamber (20) to a detection chamber (10), which comprises a through hole (135) that allows gases circulation between the detection chamber and the collection chamber, and a sheath (140) that prevents liquid samples from entering into the detection chamber from the collection chamber via the through hole. The detection chamber contains test reagent strips (120) to detect whether samples contain interested analytes. The detection device further comprises a protrusion (131) that enables the detection device standing tilted in the traverse direction. The detection method comprises collecting liquid samples as the first step, followed by standing the device tilted in its traverse direction through a protrusion support, and detecting whether samples contain the analytes.
摘要翻译：公开了一种检测装置和检测方法。检测装置包括允许液体样品从收集室（20）流到检测室（10）的样品入口（132），其包括通孔（135），该通孔允许在检测室和收集室之间的气体循环以及防止液体样品经由通孔从收集室进入检测室的护套（140）。检测室包含测试试剂条（120），以检测样品是否含有感兴趣的分析物。检测装置还包括使检测装置能够在横动方向上站立倾斜的突起（131）。检测方法包括以第一步骤收集液体样品，然后使装置在其横向方向上倾斜穿过突出支撑件，并检测样品是否含有分析物。

7. 发明申请

US20090308185A1 DEVICE FOR DETECTING ANALYTES IN FLUID SAMPLES 审中-公开
标题翻译：用于检测流体样品中分析物的装置
公开(公告)号：US20090308185A1
公开(公告)日：2009-12-17
申请号：US12091368
申请日：2006-10-20
申请人： Yuzhang Wu , Haipeng Hu , Jielin Dai , Lijian Gou
发明人： Yuzhang Wu , Haipeng Hu , Jielin Dai , Lijian Gou
IPC分类号： G01N33/00
CPC分类号： G01N33/54366 , A61B10/007 , B01L3/502 , B01L2300/0663 , B01L2300/087 , B01L2400/0478 , Y10T436/2575
摘要： The present invention provides a device (100) for detecting the presence of an analyte in a liquid sample. The device (100) has an opening (115) for introducing the liquid sample into a first chamber (301) for collecting the liquid sample, and a second chamber (601) connected to the first chamber (301) by a passageway (205) and containing a test element. The device also has a third chamber (701) connected to the second chamber (601) by a channel and containing a movable member (311) having first and second positions. The third chamber (701) is divided by the movable member (311) into first (901) and second (902) zones, and the first zone (901) has a vent hole (165). The movable member (311) is in contact with at least one wall of the third chamber (701) to prevent gas communication between the first and second zones (901, 902).
摘要翻译：本发明提供一种用于检测液体样品中分析物的存在的装置（100）。装置（100）具有用于将液体样品引入用于收集液体样品的第一室（301）的开口（115）和通过通道（205）连接到第一室（301）的第二室（601）并包含测试元素。该装置还具有通过通道连接到第二室（601）的第三室（701）并且容纳具有第一和第二位置的可动构件（311）。第三室（701）由可移动部件（311）分成第一（901）和第二（902）区域，第一区域（901）具有通气孔（165）。可移动构件（311）与第三腔室（701）的至少一个壁接触，以防止第一和第二区域（901,902）之间的气体连通。

8. 发明授权

US10073088B2 Detection device for detecting analytes in liquid specimen 有权
公开(公告)号：US10073088B2
公开(公告)日：2018-09-11
申请号：US13636326
申请日：2011-03-25
申请人： Lin Hu , Haipeng Hu , Yinfei Wu
发明人： Lin Hu , Haipeng Hu , Yinfei Wu
IPC分类号： G01N33/53 , B01L3/00
CPC分类号： G01N33/5302 , B01L3/502 , B01L3/508 , B01L2300/042 , B01L2400/0655 , Y10T436/141111 , Y10T436/142222 , Y10T436/145555 , Y10T436/146666 , Y10T436/147777 , Y10T436/173076 , Y10T436/173845
摘要： A detection device for detecting analytes in liquid specimen is provided. The detection device comprises: a specimen chamber for collecting or storing a liquid specimen; a detecting chamber for containing a detecting element; and a through hole for transferring the liquid specimen between the specimen chamber and the detecting chamber. The through hole can be opened or self-sealed. The sealing or opening of the through hole controls whether or not the liquid specimen in the specimen chamber enters the detecting chamber via the through hole. Furthermore, a detection method is provided.

9. 发明申请

US20130045501A1 Detection Device for Detecting Analytes in Liquid Specimen 审中-公开
标题翻译：用于检测液体样品中分析物的检测装置
公开(公告)号：US20130045501A1
公开(公告)日：2013-02-21
申请号：US13636326
申请日：2011-03-25
申请人： Lin Hu , Haipeng Hu , Yinfei Wu
发明人： Lin Hu , Haipeng Hu , Yinfei Wu
IPC分类号： G01N33/53 , G01N33/04 , G01N33/14 , G01N33/94 , G01N33/70 , G01N33/72 , G01N33/50 , G01N33/74 , G01N33/02 , C12Q1/04
CPC分类号： G01N33/5302 , B01L3/502 , B01L3/508 , B01L2300/042 , B01L2400/0655 , Y10T436/141111 , Y10T436/142222 , Y10T436/145555 , Y10T436/146666 , Y10T436/147777 , Y10T436/173076 , Y10T436/173845
摘要： A detection device for detecting analytes in liquid specimen is provided. The detection device comprises: a specimen chamber for collecting or storing a liquid specimen; a detecting chamber for containing a detecting element; and a through hole for transferring the liquid specimen between the specimen chamber and the detecting chamber. The through hole can be opened or self-sealed. The sealing or opening of the through hole controls whether or not the liquid specimen in the specimen chamber enters the detecting chamber via the through hole. Furthermore, a detection method is provided.
摘要翻译：提供了用于检测液体试样中的分析物的检测装置。检测装置包括：用于收集或储存液体样本的标本室; 检测室，用于容纳检测元件; 以及用于在试样室和检测室之间输送液体试样的通孔。通孔可以打开或自密封。通孔的密封或打开控制样品室中的液体样本是否经由通孔进入检测室。此外，提供了一种检测方法。

10. 发明授权

US08323583B2 Detection device 有权
标题翻译：检测装置
公开(公告)号：US08323583B2
公开(公告)日：2012-12-04
申请号：US13143068
申请日：2010-01-05
申请人： Lijian Gou , Haipeng Hu
发明人： Lijian Gou , Haipeng Hu
IPC分类号： G01N1/02 , G01N31/22
CPC分类号： B01L3/508 , A61B10/007 , A61B10/0096 , A61B2010/0009 , B01L2200/0684 , B01L2200/0689 , B01L2300/047 , B01L2300/048 , B01L2300/0609 , B01L2300/0663 , B01L2300/0825 , B01L2300/126
摘要： A detection device and a detection method are disclosed. The detection device comprises a sample inlet (132) that allows liquid samples flowing from a collection chamber (20) to a detection chamber (10), which comprises a through hole (135) that allows gases circulation between the detection chamber and the collection chamber, and a sheath (140) that prevents liquid samples from entering into the detection chamber from the collection chamber via the through hole. The detection chamber contains test reagent strips (120) to detect whether samples contain interested analytes. The detection device further comprises a protrusion (131) that enables the detection device standing tilted in the traverse direction. The detection method comprises collecting liquid samples as the first step, followed by standing the device tilted in its traverse direction through a protrusion support, and detecting whether samples contain the analytes.
摘要翻译：公开了一种检测装置和检测方法。检测装置包括允许液体样品从收集室（20）流到检测室（10）的样品入口（132），其包括通孔（135），该通孔允许在检测室和收集室之间的气体循环以及防止液体样品经由通孔从收集室进入检测室的护套（140）。检测室包含测试试剂条（120），以检测样品是否含有感兴趣的分析物。检测装置还包括使检测装置能够在横动方向上站立倾斜的突起（131）。检测方法包括以第一步骤收集液体样品，然后使装置在其横向方向上倾斜穿过突出支撑件，并检测样品是否含有分析物。

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