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1. 发明授权

US07814479B2 Simultaneous download to multiple targets 有权
标题翻译：同时下载到多个目标
公开(公告)号：US07814479B2
公开(公告)日：2010-10-12
申请号：US11304407
申请日：2005-12-14
申请人： Darren C. Douglas , Jason James Graves , Lei Liu , Sudhir Gurunandan Rao
发明人： Darren C. Douglas , Jason James Graves , Lei Liu , Sudhir Gurunandan Rao
IPC分类号： G06F9/44
CPC分类号： H04L67/34 , G06F8/61 , G06F11/20 , G06F11/202
摘要： Provided are a techniques for processing a download. Under control of a first target device, a download command is received via a first communication medium that indicates that an update is to be downloaded. The download command is issued to a second target device via a second communication medium, wherein the second communication medium is a private device communication medium that enables private communication between the first target device and the second target device. The update is received via the first communication medium. In response to determining that the update has been downloaded, run with the update.
摘要翻译：提供了一种处理下载的技术。在第一目标设备的控制下，经由指示要下载更新的第一通信介质接收下载命令。经由第二通信介质向第二目标设备发出下载命令，其中第二通信介质是允许第一目标设备和第二目标设备之间的私有通信的专用设备通信介质。经由第一通信介质接收更新。为了响应确定更新已被下载，请运行该更新。

2. 发明授权

US08713551B2 Apparatus, system, and method for non-interruptively updating firmware on a redundant hardware controller 失效
标题翻译：用于在中断地更新冗余硬件控制器上的固件的装置，系统和方法
公开(公告)号：US08713551B2
公开(公告)日：2014-04-29
申请号：US11324594
申请日：2006-01-03
申请人： Darren Christopher Douglas , Jason James Graves , Lei Liu , David M. Morton
发明人： Darren Christopher Douglas , Jason James Graves , Lei Liu , David M. Morton
IPC分类号： G06F9/44 , G06F11/00
CPC分类号： G06F11/2097
摘要： An apparatus, system, and method are disclosed for non-interruptively updating firmware on a redundant hardware controller. The apparatus includes a routing module, a receiving module, and a forwarding module. The routing module routes communications between a redundant hardware controller and a service processor associated with a flash update. The receiving module receives a flash command for the flash update from the service processor via a shared serial connection. The forwarding module forwards the flash command via a dedicated point to point connection to the redundant hardware controller configured to receive the flash command over the point to point connection. The apparatus, system, and method provide a non-interruptive overlay of the firmware image on a redundant hardware controller, minimizing system downtime and user intervention.
摘要翻译：公开了用于在冗余硬件控制器上非中断地更新固件的装置，系统和方法。该装置包括路由模块，接收模块和转发模块。路由模块路由冗余硬件控制器与与闪存更新相关联的服务处理器之间的通信。接收模块通过共享串行连接从服务处理器接收闪速更新的闪存命令。转发模块通过专用点到点连接将闪存命令转发到配置为通过点对点连接接收闪存命令的冗余硬件控制器。该装置，系统和方法在冗余硬件控制器上提供固件映像的非中断覆盖，最大限度地减少系统停机时间和用户干预。

3. 发明授权

US07809993B2 Apparatus, system, and method for receiving digital instructions at devices sharing an identity 有权
标题翻译：用于在共享身份的设备处接收数字指令的装置，系统和方法
公开(公告)号：US07809993B2
公开(公告)日：2010-10-05
申请号：US11333137
申请日：2006-01-17
申请人： Joseph Edward Bolan , Darren Christopher Douglas , Jason James Graves , Shah Mohammad Rezaul Islam , Lei Liu , Yoshihiko Terashita
发明人： Joseph Edward Bolan , Darren Christopher Douglas , Jason James Graves , Shah Mohammad Rezaul Islam , Lei Liu , Yoshihiko Terashita
IPC分类号： G06F11/00
CPC分类号： G06F21/10
摘要： An apparatus, system, and method are disclosed for receiving digital instructions at devices or controllers sharing an identity. A first controller receives a digital instruction instance over a communications medium. The digital instruction instance may be a firmware instance. The first controller has ownership of the communications medium and shares the communications medium and a common identity with a second controller. An ownership module transfers ownership of the communications medium from the first controller to the second controller. The ownership module may transfer ownership in response to the first controller successfully receiving the digital instruction instance. A request module requests a retransmission of the digital instruction instance, and may request the retransmission in response to the transfer of ownership of the communications medium. The second controller receives the retransmitted digital instruction instance in response to the retransmission request.
摘要翻译：公开了用于在共享身份的设备或控制器处接收数字指令的装置，系统和方法。第一控制器通过通信介质接收数字指令实例。数字指令实例可以是固件实例。第一控制器具有通信介质的所有权，并且与第二控制器共享通信介质和公共标识。所有权模块将通信介质的所有权从第一控制器传送到第二控制器。所有权模块可以响应于第一控制器成功接收数字指令实例来转移所有权。请求模块请求数字指令实例的重传，并且可以响应于通信介质的所有权的转移来请求重传。响应于重传请求，第二控制器接收重传的数字指令实例。

4. 发明授权

US07600055B2 Apparatus, system, and method for firmware update of redundant controllers 失效
标题翻译：冗余控制器固件更新的装置，系统和方法
公开(公告)号：US07600055B2
公开(公告)日：2009-10-06
申请号：US11324436
申请日：2006-01-03
申请人： Darren C. Douglas , Jason J. Graves , Lei Liu , Keith D. Richeson , Yoshihiko Terashita
发明人： Darren C. Douglas , Jason J. Graves , Lei Liu , Keith D. Richeson , Yoshihiko Terashita
IPC分类号： G06F3/00 , G06F11/00
CPC分类号： G06F8/65 , G06F11/2089
摘要： An apparatus, system, and method are disclosed for updating firmware to a plurality of memory devices residing on disparate controllers wherein each controller includes an identical communication path address. A management module writes a firmware image to a memory device residing on a primary controller. The primary controller, in turn, copies the firmware image to another memory device residing on a secondary controller. In this manner, the apparatus, system, and method may update firmware on a plurality of memory devices. Because the primary controller is tasked with updating the secondary controller, the management module is only aware that the firmware of the primary controller has been updated. In this manner, updating of the firmware on the secondary controller is transparent to the management module.
摘要翻译：公开了一种用于将固件更新到位于不同控制器上的多个存储器设备的装置，系统和方法，其中每个控制器包括相同的通信路径地址。管理模块将固件映像写入驻留在主控制器上的存储设备。主控制器又将固件映像复制到位于辅助控制器上的另一个存储设备。以这种方式，设备，系统和方法可以更新多个存储设备上的固件。由于主控制器的任务是更新辅助控制器，所以管理模块只知道主控制器的固件已更新。以这种方式，次级控制器上的固件的更新对于管理模块是透明的。

5. 发明申请

US20190298715A1 IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY 审中-公开
公开(公告)号：US20190298715A1
公开(公告)日：2019-10-03
申请号：US16338085
申请日：2017-09-29
申请人： Gregory Motz , Konstantinos John Mavrakias , Jinbiao Liu , Lei Liu , Qiangang Zheng , Guoliang Xun , Qitao Xiao , Novartis AG , The Trustees of the University of Pennsylvania
发明人： Gregory Motz , Konstantinos John Mavrakias , Jinbiao Liu , Lei Liu , Qiangang Zheng , Guoliang Xun , Qitao Xiao
IPC分类号： A61K31/496 , A61K31/444 , C12N15/113 , A61K31/404 , A61K35/17
摘要： Provided herein is the use of LSD1 inhibitors in connection with use and manufacture of immune effector cells (e.g., T cells, NK cells), e.g., engineered to express a chimeric antigen receptor (CAR), to treat a subject having a disease, e.g., a disease associated with expression of a tumor antigen.

6. 发明申请

US20190196448A1 Method for Simulating Daylight Performance of Buildings Based on Regional Daylight Climate Data 审中-公开
公开(公告)号：US20190196448A1
公开(公告)日：2019-06-27
申请号：US16010497
申请日：2018-06-17
申请人： Cheng Sun , Yunsong Han , Ying Zi , Dagang Qu , Yongheng Jia , Lei Liu , Hong Yu
发明人： Cheng Sun , Yunsong Han , Ying Zi , Dagang Qu , Yongheng Jia , Lei Liu , Hong Yu
IPC分类号： G05B19/4099 , B33Y50/02
摘要： The present invention provides a method for simulating daylight performance of buildings based on regional daylight climate data. The method comprises the steps of: establishing a regional sky luminance distribution database from measured data; mapping sky luminance data to an artificial sky lamp group; using a 3D printing machine to fabricate a scaled physical model based on real parameters of the building to be simulated; and using the scaled physical model in the artificial sky integrated with regional sky luminance distribution data to make the daylight performance simulation. This method can achieve high-precision simulation of the daylight performance of buildings by using regional sky daylight climate data with a highly accurate physical model of the building.

7. 发明申请

US20150283318A1 Methods to detect and treat diseases 审中-公开
标题翻译：检测和治疗疾病的方法
公开(公告)号：US20150283318A1
公开(公告)日：2015-10-08
申请号：US14246117
申请日：2014-04-06
申请人： Tianxin Wang , Wenbin Ma , Yiwang Chen , Lei Liu
发明人： Tianxin Wang , Wenbin Ma , Yiwang Chen , Lei Liu
IPC分类号： A61M1/36 , A61N5/10 , A61B18/04 , A61B18/18 , A61B18/02 , G01N33/48 , A61B18/20
CPC分类号： A61M1/3679 , A61B18/02 , A61B18/04 , A61B18/1815 , A61B18/20 , A61B2018/00577 , A61M1/3472 , A61M1/3486 , A61M1/3621 , A61M1/3681 , A61M1/3683 , A61M1/3687 , A61M2202/0415 , A61M2205/053 , A61M2205/75 , A61N5/10 , G01N33/48
摘要： The current invention discloses methods to treat disease caused by virus infection, bacterial infection, parasites infection, autoimmune disease, disease caused by production of unwanted antibodies, sepsis as well as methods to treat cancer and methods for virus infection detection using blood purification method. The current invention provides a method to treat pathogen infection by inactivating the pathogens in the blood. During the treatment, blood is withdrawn from a patient and is separated into its plasma and cellular components. The plasma portion is treated with physical means such as UV radiation to inactivate the pathogens inside and then is returned to the patient. The current invention also provide a method to treat cancer especially to prevent tumor metastasis and tumor recurrence by removing and/or inactivating (e.g. killing) the circulating tumor cells (CTC) in the blood after removing the tumor or treating the tumor with therapeutical means.
摘要翻译：本发明公开了使用血液净化方法治疗由病毒感染，细菌感染，寄生虫感染，自身免疫病，由不想要的抗体产生引起的疾病，败血症以及治疗癌症的方法等疾病的方法。本发明提供了通过灭活血液中的病原体来治疗病原体感染的方法。在治疗期间，将血液从患者中取出并分离成其血浆和细胞组分。用诸如UV辐射的物理手段处理血浆部分以使内部的病原体灭活，然后返回到患者体内。本发明还提供了一种治疗癌症的方法，特别是通过在除去肿瘤之后除去和/或灭活（例如杀死）血液中的循环肿瘤细胞（CTC）或用治疗方法治疗肿瘤来预防肿瘤转移和肿瘤复发。

8. 发明授权

US09125418B2 Agricultural compositions 有权
标题翻译：农作物
公开(公告)号：US09125418B2
公开(公告)日：2015-09-08
申请号：US12369123
申请日：2009-02-11
申请人： Kuide Qin , Lei Liu
发明人： Kuide Qin , Lei Liu
IPC分类号： A01N59/16 , A01N25/04 , A01N25/30 , A01N47/14 , A01N25/22
CPC分类号： A01N59/16 , A01N25/22 , A01N25/04 , A01N25/30 , A01N47/14 , A01N2300/00
摘要： Compositions have been discovered that are suitable for forming a stable dispersion. The compositions comprise an agriculturally active compound and a multivalent metal oligomeric or polymeric compound having a molecular weight of from about 150 to about 15,000 Daltons.
摘要翻译：已发现适于形成稳定分散体的组合物。组合物包含农业活性化合物和分子量为约150至约15,000道尔顿的多价金属低聚物或聚合物。

9. 发明授权

US08805759B1 System and method for psychographic profiling of targeted populations of individuals 有权
标题翻译：针对目标人群的心理剖析的系统和方法
公开(公告)号：US08805759B1
公开(公告)日：2014-08-12
申请号：US12538224
申请日：2009-08-10
申请人： Alexandra N. Cha , Hyuk Cha , Lei Liu
发明人： Alexandra N. Cha , Hyuk Cha , Lei Liu
IPC分类号： G06F17/00 , G06N5/00 , G06N99/00 , G06N5/04 , G06Q10/10
CPC分类号： G06F17/00 , G06N5/00 , G06N5/04 , G06N99/005 , G06Q10/10
摘要： A system and method are provided for psychographically profiling a target population of individuals, programmably implemented in a server apparatus. The psychographic segmentation portion includes a questionnaire processing part, a segment solution part, and a typing tool part. The questionnaire processing part acquires a plurality of responses to a predetermined set of questionnaire questions by an initial pool of target population members. The questionnaire processing part uses a combination of weighted statistical methodologies to arrive at a rule-based decision on whether the question would serve as a good wedge variable. Optionally, the rule based decision is then compared to an expert's opinion and the weights and threshold parameters of the weighted statistical combination are adjusted accordingly to more accurately match the expert's decision. The identified wedge variables are used for effectively segregating the target population into groups of homogenous individuals. The typing tool part selectively generates an abbreviated set of questions from the predetermined set of questionnaire questions for profiling an individual respondent to at least one of the segments.
摘要翻译：提供了一种系统和方法，用于心理地剖析个体的目标群体，可编程地在服务器设备中实现。心理分割部分包括问卷处理部分，片段解决部分和打字工具部分。问卷处理部分通过初始的目标人群成员获取对预定的一组问卷问题的多个响应。问卷处理部分使用加权统计方法的组合来得出关于该问题是否将作为一个好的楔形变量的基于规则的决策。可选地，然后将基于规则的决策与专家意见进行比较，并相应地调整加权统计组合的权重和阈值参数以更准确地匹配专家的决定。确定的楔形变量用于有效地将目标群体分离成同质个体群体。打字工具部分从预定的一组问卷问题中选择性地生成一组简短的问题，以便对个别回答者进行分析，以对至少一个分段进行分析。

10. 发明授权

US08796476B2 Pesticide compositions exhibiting enhanced activity and methods for preparing same 有权
标题翻译：表现出增强活性的农药组合物及其制备方法
公开(公告)号：US08796476B2
公开(公告)日：2014-08-05
申请号：US12768263
申请日：2010-04-27
申请人： Stephen L. Wilson , Lei Liu , James D. Thomas , Raymond E. Boucher, Jr. , James E. Dripps , Margaret S. Kempe , Martin C. Logan , Douglas J. Linscott , John M. Atkinson
发明人： Stephen L. Wilson , Lei Liu , James D. Thomas , Raymond E. Boucher, Jr. , James E. Dripps , Margaret S. Kempe , Martin C. Logan , Douglas J. Linscott , John M. Atkinson
IPC分类号： A01N25/08 , A01N43/00 , A01N35/06 , A01N35/08 , A01N37/36 , A01N37/42 , A01N43/16 , A01N43/22 , A01N43/90 , A01N59/16 , A01N25/22
CPC分类号： A01N25/00 , A01N25/08 , A01N25/22 , A01N35/06 , A01N35/08 , A01N37/36 , A01N37/42 , A01N43/00 , A01N43/16 , A01N43/22 , A01N43/90 , A01N59/16 , A01N25/10 , A01N59/22 , A01N2300/00
摘要： Pest controlling compositions exhibiting enhanced pesticidal activity levels and methods for preparing the same are disclosed. In one embodiment, a method includes providing a liquid composition that includes at least one pesticide and at least one co-ingredient that enhances pesticidal activity of the composition compared to a composition dissimilar only in not having the at least one co-ingredient. The at least one co-ingredient may include at least one metal oxide, a combination of at least one transition metal salt and at least one proteinaceous material or a combination of at least one proteinaceous material and at least one polymeric material. The method further includes spray drying the liquid composition to provide a solid composition. In one aspect of this embodiment, the solid composition provided by the spray drying exhibits enhanced pesticidal activity compared to the liquid composition.
摘要翻译：公开了具有增强的杀虫活性水平的害虫控制组合物及其制备方法。在一个实施方案中，一种方法包括提供液体组合物，其包含至少一种农药和至少一种辅助成分，其与仅在不具有至少一种辅助成分的组合物不同的组合物中相比提高了组合物的杀虫活性。至少一种辅助成分可以包括至少一种金属氧化物，至少一种过渡金属盐和至少一种蛋白质材料的组合，或至少一种蛋白质材料和至少一种聚合物材料的组合。该方法还包括喷雾干燥液体组合物以提供固体组合物。在该实施方案的一个方面，与液体组合物相比，通过喷雾干燥提供的固体组合物显示出增强的杀虫活性。

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