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    • 1. 发明申请
    • METHOD AND APPARATUS FOR PERITONEAL HYPOTHERMIA AND/OR RESUSCITATION
    • 方法和装置用于腹膜上皮和/或恢复
    • US20070106247A1
    • 2007-05-10
    • US11552090
    • 2006-10-23
    • Daniel BurnettShane MangrumJared Blanton
    • Daniel BurnettShane MangrumJared Blanton
    • A61M31/00
    • A61F7/12A61F2007/0094A61F2007/126A61M1/28A61M1/281A61M1/285A61M1/32A61M25/003A61M25/007A61M31/00A61M2025/0034A61M2025/0037
    • Embodiments of the invention provide apparatus, systems and methods for introducing fluids into a body cavity for hypothermic, resuscitative, or other treatment. One embodiment provides an apparatus for introducing fluids into a peritoneal cavity comprising an access device for insertion into subcutaneous tissue, an infusion member and an advancement member. The access device includes a lumen, a proximal end, a tissue penetrating distal end and a stop for controlling the depth of the distal end into tissue. The infusion member includes an infusion lumen, a removal lumen and at least one sensor and is advanceable from a lumen of the access device into the peritoneal cavity. The advancement member is removably positionable in an infusion member lumen and has sufficient column strength to advance the infusion member tip through abdominal wall tissue into the peritoneal cavity. When the advancement member is removed, the infusion member tip is substantially atraumatic.
    • 本发明的实施方案提供了用于将体液引入体腔以进行低体温,复苏或其它治疗的装置,系统和方法。 一个实施例提供了一种用于将流体引入腹膜腔的装置,包括用于插入皮下组织的进入装置,输注构件和前进构件。 进入装置包括内腔,近端,组织穿透远端和用于控制远端进入组织的深度的止挡件。 输注构件包括输液腔,移除腔和至少一个传感器,并且可从进入装置的内腔进入腹膜腔。 推进构件可移除地定位在输注构件内腔中并且具有足够的柱强度以将输注构件尖端通过腹壁组织推进到腹膜腔中。 当推进构件被移除时,输液构件尖端基本上是无创伤的。
    • 2. 发明授权
    • Method and apparatus for treating wound using negative pressure therapy
    • 用负压疗法治疗伤口的方法和装置
    • US07896823B2
    • 2011-03-01
    • US11332756
    • 2006-01-17
    • Shane MangrumDaniel Burnett
    • Shane MangrumDaniel Burnett
    • A61H7/00A61H23/00A61F13/06A61F13/66
    • A61H9/005A61H2201/1238A61H2205/10A61H2209/00
    • Devices that employ external compression stocking-type garments in the treatment of edema, chronic wounds, deep venous thrombosis prevention or claudication all share a number of significant limitations. These include the frequent need for custom fitting to assure an appropriate fit, vigilant maintenance to assure a continued “good fit,” limited compliance with proper use by patients and difficulty of application. There is a large body of evidence demonstrating that patients often decline to wear the compressive stockings as prescribed or in the form that would be most beneficial because they find these devices to be difficult to put on and take off.Building on the limitations of existing therapies, and distilled lessons learned from the field of prosthetics and wound healing, the present invention employs vacuum-assisted negative pressure to provide compression and help pump fluid from the tissues of affected limbs. The device is embodied in the form of a flexible stocking-like garment that will utilize a pumping mechanism to generate negative pressure around the limb and thus create vacuum compression that will mobilize fluid in a limb and increase venous return to the heart. Through the use of a circumferential wrap, the present invention provides a major advance in both the distribution of vacuum and the securing of the device over the limb.
    • 使用外部压缩放养型衣服治疗水肿,慢性伤口,深静脉血栓预防或跛行的装置都具有一些显着的局限性。 这些包括经常需要定制配件,以确保适当的配合,警惕的维护,以确保持续的“良好配合”,限制患者适当使用的合规和应用难度。 有大量证据表明,患者经常拒绝按规定佩戴压缩丝袜,或以最有利的形式,因为他们发现这些装置难以穿上和起飞。 基于现有疗法的局限性,以及从假肢和伤口愈合领域获得的经验教训,本发明采用真空辅助负压来提供压迫并帮助受影响肢体的组织泵送液体。 该装置体现为柔性袜子样衣服的形式,其将利用泵送机构在肢体周围产生负压,从而产生将在肢体中调动流体并增加静脉返回心脏的真空压缩。 通过使用圆周包裹体,本发明提供了真空分配和将装置固定在肢体上的重大进步。
    • 3. 发明申请
    • Method and apparatus for personal isolation and/or protection
    • 用于个人隔离和/或保护的方法和装置
    • US20070163586A1
    • 2007-07-19
    • US11332799
    • 2006-01-17
    • Daniel BurnettShane Mangrum
    • Daniel BurnettShane Mangrum
    • A61M16/00A62B23/02
    • A62B18/003A62B23/02
    • The device of the present invention may create and maintain a pressure differential in the vicinity of the user's nasopharynx. Using a portable filter and pressurized air source, the region of the user's nasopharynx can be subjected to positive or negative pressured air. Positive pressure will prevent exposure surrounding air while negative air pressure will isolate those around the user from potential toxins or pathogens exhaled from the user. In the positive pressure embodiments, the surrounding air may be displaced by the positive pressure environment preventing exposure to ambient air in all instances other than a direct blast of high flow air directed at the users nasopharynx (such as an uncovered and maliciously directed sneeze). If adequate pressure is used, though, even this scenario would not allow for transmission of airborne illness with repulsion of any infective droplets being repelled by the positive pressure created. In the negative pressure embodiment, exhaled air may be evacuated from the nasopharynx, filtered and returned to the user's surroundings to prevent exposure to those around the user. The device of the present invention may be incorporated into a variety of garments, accessories or existing isolation devices (ie face masks) to improve their efficacy. Alternatively, the device may also be attached to an air source in the user's vicinity and simply provide filtration of the air prior to delivery to the region surrounding the user.
    • 本发明的装置可以产生并维持使用者鼻咽附近的压力差。 使用便携式过滤器和加压空气源,使用者的鼻咽区域可以受到正压或负压的空气。 正压力将防止周围空气暴露,而负空气压力会使使用者周围的人体免受潜在的毒素或从使用者呼出的病原体。 在正压实施例中,周围的空气可以通过正压环境来移位,除了直接喷射用户鼻咽的高流量空气(例如未覆盖和恶意定向的打喷嚏)之外的所有情况下,防止暴露于环境空气。 如果使用足够的压力,即使这种情况也不允许传播空气传播的疾病,因为所产生的正压力被任何感染性液滴排斥。 在负压实施例中,呼出的空气可以从鼻咽排出,过滤并返回到使用者的周围环境,以防止暴露于使用者身边。 本发明的装置可以并入到各种衣服,附件或现有的隔离装置(即面罩)中以提高其功效。 或者,装置还可以附接到使用者附近的空气源,并且在输送到用户周围的区域之前简单地提供空气的过滤。
    • 4. 发明申请
    • Method and apparatus for negative pressure therapy
    • 负压治疗方法和装置
    • US20070167884A1
    • 2007-07-19
    • US11332756
    • 2006-01-17
    • Shane MangrumDaniel Burnett
    • Shane MangrumDaniel Burnett
    • A61H7/00
    • A61H9/005A61H2201/1238A61H2205/10A61H2209/00
    • Devices that employ external compression stocking-type garments in the treatment of edema, chronic wounds, deep venous thrombosis prevention or claudication all share a number of significant limitations. These include the frequent need for custom fitting to assure an appropriate fit, vigilant maintenance to assure a continued “good fit,” limited compliance with proper use by patients and difficulty of application. There is a large body of evidence demonstrating that patients often decline to wear the compressive stockings as prescribed or in the form that would be most beneficial because they find these devices to be difficult to put on and take off. Building on the limitations of existing therapies, and distilled lessons learned from the field of prosthetics and wound healing, the present invention employs vacuum-assisted negative pressure to provide compression and help pump fluid from the tissues of affected limbs. The device is embodied in the form of a flexible stocking-like garment that will utilize a pumping mechanism to generate negative pressure around the limb and thus create vacuum compression that will mobilize fluid in a limb and increase venous return to the heart. Through the use of a circumferential wrap, the present invention provides a major advance in both the distribution of vacuum and the securing of the device over the limb.
    • 使用外部压缩放养型衣服治疗水肿,慢性伤口,深静脉血栓预防或跛行的装置都具有一些显着的局限性。 这些包括经常需要定制配件,以确保适当的配合,警惕的维护,以确保持续的“良好配合”,限制患者适当使用的合规和应用难度。 有大量证据表明,患者经常拒绝按规定佩戴压缩丝袜,或以最有利的形式,因为他们发现这些装置难以穿上和起飞。 基于现有疗法的局限性,以及从假肢和伤口愈合领域获得的经验教训,本发明采用真空辅助负压来提供压迫并帮助受影响肢体的组织泵送液体。 该装置体现为柔性袜子样衣服的形式,其将利用泵送机构在肢体周围产生负压,从而产生将在肢体中调动流体并增加静脉返回心脏的真空压缩。 通过使用圆周包裹体,本发明提供了真空分配和将装置固定在肢体上的重大进步。
    • 5. 发明申请
    • Method and apparatus for low frequency induction therapy for the treatment of urinary incontinence and overactive bladder
    • 用于治疗尿失禁和膀胱过度活动症的低频诱导治疗方法和装置
    • US20070167990A1
    • 2007-07-19
    • US11332797
    • 2006-01-17
    • Shane MangrumDaniel Burnett
    • Shane MangrumDaniel Burnett
    • A61N1/00
    • A61N1/40A61N1/36007
    • Current treatment options for Overactive Bladder and Urinary Incontinence include exercise and behavioral modifications, pharmacological therapies, surgical intervention, and neuromodulation. Although each of these treatments is used in the treatment of individuals with these conditions, each has severe limitations. Building on the limitations of existing therapies, and with the distillation of lessons learned from the field of pulsed electric stimulation, the present invention employs Low Frequency Induction Therapy for the delivery of an effective, cost efficient, noninvasive alternative to available treatment options. The device of the present application allows for consistent, user-friendly modulation of the pudendal nerve and the sacral plexus, via pulsed electromagnetic stimulation of the posterior tibial nerve, on an outpatient basis. The device has two primary components: a programmable Logic Controller (LC), which generates the required current, and a Conductive Wrap (CW), through which the current is channeled in generating the pulsed electromagnetic fields.
    • 过度活动性膀胱和尿失禁的当前治疗方案包括运动和行为修改,药理疗法,外科手术和神经调节。 虽然这些治疗中的每一种都用于治疗具有这些病症的个体,但是每种治疗都具有严重的限制。 基于现有疗法的局限性,并且从脉冲电刺激领域获得的经验教训,本发明采用低频感应治疗来提供有效的,成本有效的,无创的替代现有治疗方案。 本申请的装置允许通过脉搏电磁刺激后胫神经在门诊的基础上对阴部神经和骶神经丛进行一致的,用户友好的调制。 该器件具有两个主要组件:产生所需电流的可编程逻辑控制器(LC)和导电卷绕(CW),通过该导电卷绕电流产生脉冲电磁场​​。
    • 6. 发明授权
    • Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues
    • 用于电磁刺激神经,肌肉和身体组织的方法和装置
    • US06701185B2
    • 2004-03-02
    • US10077434
    • 2002-02-19
    • Daniel BurnettShane Mangrum
    • Daniel BurnettShane Mangrum
    • A61N100
    • A61N1/36071A61N1/40A61N2/006A61N2/008A61N2/02
    • An electromagnetic stimulation device which is comprised of a plurality of overlapping coils which are able to be independently energized in a predetermined sequence such that each coil will generate its own independent electromagnetic field and significantly increase the adjacent field. The coils are co-planar and are disposed in an ergonomic body wrap, which is properly marked to permit an unskilled patient to locate the body wrap, on a particular part of the body, of the patient so that the stimulation coils will maximize the electromagnetic stimulation on the selected nerves, muscles, and/or body tissues near the treated area. The device can be used to treat medical conditions including: muscular atrophy, neuropathic bladder and bowel, musculoskeletal pain, arthritis, as well as possible future applications in the prevention of deep vein thrombosis and weight reduction.
    • 一种电磁刺激装置,其由多个重叠的线圈组成,能够以预定的顺序独立地通电,使得每个线圈将产生其自己独立的电磁场并显着地增加相邻的场。 线圈是共面的并且被布置在符合人体工程学的身体包裹中,其被适当地标记以允许不熟练的患者将身体包裹物定位在患者的特定部位上,使得刺激线圈将使电磁 对被处理区域附近的所选择的神经,肌肉和/或身体组织的刺激。 该装置可用于治疗包括肌肉萎缩,神经性膀胱和肠道,肌肉骨骼疼痛,关节炎以及预防深静脉血栓形成和减轻体重的可能的未来应用的医学状况。
    • 8. 发明申请
    • Method and apparatus for anchoring implants
    • 锚固植入物的方法和装置
    • US20060069400A1
    • 2006-03-30
    • US11234802
    • 2005-09-26
    • Daniel BurnettShane Mangrum
    • Daniel BurnettShane Mangrum
    • A61B17/00A61F2/24A61F2/04
    • A61F2/2409A61B17/064A61B2017/0641A61F2/07A61F2/848A61F2002/065A61F2220/0008A61F2220/0016
    • Methods, devices and systems facilitate retention of a variety of therapeutic devices. Devices generally include an anchoring element, which has been designed to promote fibrotic ingrowth, and an anchored device, which has been designed to firmly engage the complementary region of the anchoring element. The anchoring element may be placed in a minimally invasive procedure temporally separated from the deployment of the anchored device. Once enough time has passed to ensure appropriate fixation of the anchoring element by tissue and cellular ingrowth at the site of placement, the anchored device may then be deployed during which it firmly engages the complementary region of the anchoring element. In this manner, a firm attachment to the implantation site may be made with a minimum of required hardware. Some embodiments are delivered through a delivery tube or catheter and while some embodiments may require laparoscopy or open surgery for one or more of the placement procedures. Some embodiments anchor devices within the cardiovascular tree while others may anchor devices within the gastrointestinal, peritoneal, pleural, pulmonary, urogynecologic, nasopharyngeal or dermatologic regions of the body.
    • 方法,装置和系统便于保留各种治疗装置。 装置通常包括被设计成促进纤维化向内生长的锚固元件和已被设计成牢固地接合锚定元件的互补区域的锚定装置。 锚固元件可以放置在与锚定装置的展开暂时分离的微创过程中。 一旦足够的时间过去以确保锚固元件通过组织和细胞向内生长在放置位置处的适当固定,则锚定装置然后可以被展开,在该位置中,其牢固地接合锚定元件的互补区域。 以这种方式,可以以最少的所需硬件来进行到植入部位的牢固附着。 一些实施例通过输送管或导管递送,并且虽然一些实施例可能需要腹腔镜检查或开放手术来进行一个或多个放置过程。 一些实施例锚固装置在心血管树中,而另一些实施例可以将装置锚定在身体的胃肠,腹膜,胸膜,肺,泌尿,妇科,鼻咽或皮肤病学区域内。