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1. 发明申请

US20180264185A9 PERITONEAL DIALYSIS MACHINE 审中-公开
公开(公告)号：US20180264185A9
公开(公告)日：2018-09-20
申请号：US14553104
申请日：2014-11-25
申请人： Baxter International Inc. , Baxter Healthcare S.A.
发明人： Robert W. Childers
IPC分类号： A61M1/28 , A61M1/36 , G01L7/00 , G01M3/04
CPC分类号： A61M1/284 , A61B5/02042 , A61M1/28 , A61M1/281 , A61M1/288 , A61M1/3621 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3644 , A61M1/3652 , A61M2205/122 , A61M2205/128 , A61M2205/70 , G01L7/00 , G01M3/04
摘要： A method for operating a dialysis cassette including a flexible membrane that covers a pump chamber includes allowing a source of fluid to fluidly communicate with the pump chamber of the dialysis cassette, filling the pump chamber with the fluid from the source, mechanically extending the flexible membrane into the pump chamber with a piston head to expel the fluid from the pump chamber through a flow path, and directly sensing a pressure of the fluid flowing through the flow path at a location of the dialysis cassette adjacent to the pump chamber and using the sensed pressure to perform a test prior to delivering fluid to a patient.

2. 发明申请

US20180104400A1 Peritoneal Dialysis Systems, Devices, and Methods 审中-公开
公开(公告)号：US20180104400A1
公开(公告)日：2018-04-19
申请号：US15820672
申请日：2017-11-22
申请人： NXSTAGE MEDICAL INC.
发明人： Jeffrey H. BURBANK , James M. BRUGGER , Dennis M. TREU , Mark T. WYETH
IPC分类号： A61M1/28
CPC分类号： A61M1/282 , A61M1/1656 , A61M1/166 , A61M1/1664 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1674 , A61M1/28 , A61M1/281 , A61M1/285 , A61M1/287 , A61M1/288 , A61M2025/0002 , A61M2205/12 , A61M2205/123 , A61M2205/128 , A61M2205/14 , A61M2205/18 , A61M2205/33 , A61M2205/3331 , A61M2205/3334 , A61M2205/3351 , A61M2205/3355 , A61M2205/52 , A61M2230/005
摘要： An automated peritoneal dialysis system provides both cycler-assisted peritoneal dialysis treatment and also continuous ambulatory peritoneal dialysis (CAPD). The system includes a fluid preparation and treatment device with a concentrate dilution components connected to a source of purified water and medicament concentrate. The treatment device has at least one mixing container connected via a pump and valves to the sources, the valves and the pump mixing and diluting the concentrate to form a medicament. An auxiliary port is provided for attaching a CAPD container and for receiving medicament. A controller is programmed to control the fluid preparation and treatment device to implement one or more cycler-assisted peritoneal dialysis treatment cycles using medicament from the mixing container and also to control the preparation of additional dialysate at the end of the cycler-assisted peritoneal dialysis treatment cycles to dispense additional dialysate through the auxiliary port for use in CAPD.

3. 发明授权

US09907897B2 Peritoneal dialysis systems, devices, and methods 有权
公开(公告)号：US09907897B2
公开(公告)日：2018-03-06
申请号：US14006763
申请日：2012-03-23
申请人： Jeffrey H. Burbank , James M. Brugger , Dennis M. Treu , Mark T. Wyeth
发明人： Jeffrey H. Burbank , James M. Brugger , Dennis M. Treu , Mark T. Wyeth
IPC分类号： A61M1/28 , A61M1/16 , A61M25/00
CPC分类号： A61M1/28 , A61M1/1656 , A61M1/166 , A61M1/1664 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1674 , A61M1/281 , A61M1/282 , A61M1/285 , A61M1/287 , A61M1/288 , A61M2025/0002 , A61M2205/12 , A61M2205/123 , A61M2205/128 , A61M2205/14 , A61M2205/18 , A61M2205/33 , A61M2205/3331 , A61M2205/3334 , A61M2205/3351 , A61M2205/3355 , A61M2205/52 , A61M2230/005
摘要： An automated peritoneal dialysis system provides various features including prescription-driven dialysis fluid preparation, an integrated disposable fluid circuit, and sensor capabilities that allow accurate filing and draining control with high safety margins. Features include a peritoneal fluid circuit with a pressure sensor at either end and methods and devices for using the pressure signals. Other features and embodiments are disclosed.

4. 发明授权

US09855377B2 Dialysis system including heparin injection 有权
公开(公告)号：US09855377B2
公开(公告)日：2018-01-02
申请号：US14594349
申请日：2015-01-12
申请人： Baxter International Inc. , Baxter Healthcare S.A.
发明人： Robert W. Childers , Thomas D. Kelly , Rodolfo Roger
IPC分类号： A61M1/16 , A61M1/28 , A61M1/34 , A61M1/36 , B01D61/30
CPC分类号： A61M1/16 , A61M1/14 , A61M1/1601 , A61M1/1605 , A61M1/1621 , A61M1/1649 , A61M1/166 , A61M1/168 , A61M1/1686 , A61M1/1688 , A61M1/28 , A61M1/281 , A61M1/3465 , A61M1/3643 , A61M1/3644 , A61M1/3649 , A61M1/3652 , A61M2205/128 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3344 , A61M2205/3379 , A61M2205/6036 , B01D61/243 , B01D61/30 , Y10T29/49826 , Y10T137/0396 , Y10T137/87893
摘要： A dialysis system includes a dialysis instrument including a blood pump actuator, a dialyzer, a heparin pump, and a disposable cassette including a blood pumping portion operable with the blood pump actuator of the dialysis instrument, the blood pumping portion including an inlet and an outlet, the inlet of the blood pumping portion of the disposable cassette positioned and arranged to receive blood from an arterial line of an extracorporeal circuit, the outlet of the blood pumping portion of the disposable cassette positioned and arranged to deliver the blood to the dialyzer and to receive heparin from the heparin pump.

5. 发明授权

US09775939B2 Peritoneal dialysis systems and methods having graphical user interface 有权
公开(公告)号：US09775939B2
公开(公告)日：2017-10-03
申请号：US13967013
申请日：2013-08-14
申请人： Baxter Healthcare Inc. , Baxter Healthcare S.A.
发明人： Andrea (Krensky) Britton , Donald Busby , Eric Callahan , Robert Childers , Peter Hopping , Seyed Khorashahi , William Reese , Randall Sharo , Debra Toczko , Li Yue
IPC分类号： A61M1/00 , A61M1/26 , A61M1/28 , A61M1/16
CPC分类号： A61M1/267 , A61M1/166 , A61M1/28 , A61M1/281 , A61M1/288 , A61M2205/127 , A61M2205/50 , A61M2205/581 , A61M2205/583 , G06F19/00
摘要： A peritoneal dialysis machine including a membrane pump and a touch screen display that includes a mode-indicating portion and an operation-descriptive portion, the mode-indicating portion having a plurality of touch sensitive indicia each indicating one of a plurality of modes in which the machine can operate, the display being used to keep a patient continually informed of which one mode of at least three operating modes the machine is operating in, as the operation-descriptive portion changes to display details of a specific operation being carried out within the one mode, the indicia for each of the three operating modes always being visible to the patient while the machine is operating, the operating mode being selected by the patient touching one of the indicia on the screen.

6. 发明申请

US20170014566A1 APPARATUS AND METHOD AND FOR MONITORING AND CONTROLLING A PERITONEAL DIALYSIS THERAPY 审中-公开
标题翻译：装置和方法，用于监测和控制腹膜透析治疗
公开(公告)号：US20170014566A1
公开(公告)日：2017-01-19
申请号：US15280543
申请日：2016-09-29
申请人： BAXTER INTERNATIONAL INC.
发明人： Robert Warren Childers , Vital Eerlingen , Patrick Balteau , Duane Belongie
IPC分类号： A61M1/28
CPC分类号： A61M1/282 , A61M1/28 , A61M1/281 , A61M1/285 , A61M5/14224 , A61M2205/123 , A61M2205/128 , A61M2205/17 , A61M2205/3331 , A61M2205/3344 , A61M2205/3351 , A61M2205/3355
摘要： An apparatus for performing peritoneal dialysis includes a housing; a peritoneal dialysis supply bag supported by and/or located above the housing; a first valve for controlling gravity flow of fresh peritoneal dialysis fluid from the supply bag to a patient; a second valve for controlling gravity flow of used peritoneal dialysis fluid from the patient to a drain; and a pressure sensor positioned and arranged with respect to the gravity flow of fresh peritoneal dialysis fluid or the gravity flow of used peritoneal dialysis fluid to provide a reading used to evaluate a head height pressure.
摘要翻译：用于进行腹膜透析的装置包括壳体; 腹膜透析供应袋由壳体和/或位于壳体上方支撑; 用于控制新鲜腹膜透析液从供应袋到患者的重力流的第一阀; 用于控制使用过的腹膜透析液从患者到排水管的重力流的第二阀; 以及相对于新鲜腹膜透析液的重力流或使用的腹膜透析液的重力流定位和布置的压力传感器，以提供用于评估头部高度压力的读数。

7. 发明授权

US09511180B2 Stepper motor driven peritoneal dialysis machine 有权
标题翻译：步进电机驱动腹膜透析机
公开(公告)号：US09511180B2
公开(公告)日：2016-12-06
申请号：US13963553
申请日：2013-08-09
申请人： Baxter International Inc. , Baxter Healthcare S.A.
发明人： Andrea (Krensky) Britton , Donald Busby , Eric Callahan , Robert Childers , Peter Hopping , Seyed Khorashahi , William Reese , Randall Sharo , Debra Toczko , Li Yue
IPC分类号： A61M1/00 , A61M37/00 , A61M1/26 , A61M1/28
CPC分类号： A61M1/267 , A61M1/166 , A61M1/28 , A61M1/281 , A61M1/288 , A61M2205/127 , A61M2205/50 , A61M2205/581 , A61M2205/583 , G06F19/00
摘要： A peritoneal dialysis system includes: an enclosure including an actuation surface and a door; a stepper motor housed by the enclosure; a pump head and a solid pump piston structurally linking the pump head to the stepper motor; and a disposable unit accepted by the enclosure, the disposable unit including a flexible membrane attached to a rigid piece, the actuation surface of the enclosure and the disposable unit so configured and arranged that when the stepper motor turns and consequently translates the solid pump piston and the pump head towards the door, the pump head physically contacts and stretches the membrane from a relaxed position to a stretched position, and when the stepper motor turns and consequently translates the solid pump piston and the pump head away from the door, the membrane follows the pump head and transitions from the stretched position to the relaxed position.
摘要翻译：腹膜透析系统包括：包括致动表面和门的外壳; 由外壳容纳的步进电机; 泵头和固体泵活塞将泵头结构地连接到步进电机; 以及由外壳接受的一次性单元，一次性单元包括附接到刚性件的柔性膜，外壳的致动表面和如此构造和布置的一次性单元，使得当步进电机转动并因此平移固体泵活塞时泵头朝向门，泵头物理接触并将膜从松弛位置拉伸到拉伸位置，并且当步进电机转动并因此将固体泵活塞和泵头转动离开门时，膜依次泵头并从拉伸位置转变到松弛位置。

8. 发明授权

US09421314B2 Medical fluid cassettes and related systems and methods 有权
标题翻译：医用流体盒及相关系统及方法
公开(公告)号：US09421314B2
公开(公告)日：2016-08-23
申请号：US12836740
申请日：2010-07-15
申请人： Kulwinder S. Plahey , Lynn Jensen , Melvin D. Jensen , DeLoy Lindley , Joseph Michael Fallon
发明人： Kulwinder S. Plahey , Lynn Jensen , Melvin D. Jensen , DeLoy Lindley , Joseph Michael Fallon
IPC分类号： A61M1/28
CPC分类号： A61M1/267 , A61M1/16 , A61M1/28 , A61M1/281 , A61M2205/121 , A61M2205/505
摘要： A medical fluid delivery cassette configured for use with a medical fluid pumping system and related systems and methods. The medical fluid delivery cassette includes a base and a membrane that together define a fluid pump chamber. The medical fluid delivery cassette further includes a member configured to apply an outward force to an inner surface of the membrane.
摘要翻译：一种配置用于医疗液体泵送系统和相关系统和方法的医用流体输送盒。医用流体输送盒包括一起限定流体泵室的底座和膜。医疗流体输送盒还包括构造成向膜的内表面施加向外的力的构件。

9. 发明授权

US09348975B2 Optimizing therapy outcomes for peritoneal dialysis 有权
标题翻译：优化腹膜透析治疗效果
公开(公告)号：US09348975B2
公开(公告)日：2016-05-24
申请号：US12431458
申请日：2009-04-28
申请人： Ying-Cheng Lo , Alp Akonur , Isaac Martis
发明人： Ying-Cheng Lo , Alp Akonur , Isaac Martis
IPC分类号： G06F19/00 , A61M1/28
CPC分类号： G06F19/3481 , A61M1/28 , A61M1/281 , A61M1/282 , A61M2205/3569 , A61M2205/52 , A61M2205/6018 , A61M2205/6054 , A61M2205/6072 , G06F19/00
摘要： Peritoneal dialysis therapy outcomes have been calculated for a variety of dwell times of peritoneal dialysis fluids in the peritoneal cavities of dialysis patients using kinetic modeling. The length of dwell time should not be the same for every patient, but should vary according to the patient condition and needs. Some patients have a potential for expressing greater ultrafiltrate into the dialysis fluid, and these patients can benefit from a longer dwell time, whereas other patients with less potential will not benefit from a longer dwell time. An optimal or peak time is observed for each peritoneal dialysis therapy outcome, such as ultrafiltrate volume rate, urea clearance (Kt/V), and creatinine clearance, while minimizing hydrocarbon absorption. These values and input parameters can be used to tailor the peritoneal dialysis dwell time for each patient, estimating the peak dwell time that will yield the best therapy outcome for each patient.
摘要翻译：已经使用动力学模型计算了透析患者腹膜腔腹膜透析液的各种停留时间的腹膜透析治疗结果。每个患者的停留时间长度不应相同，但应根据患者情况和需要而变化。一些患者有可能在透析液中表达更多的超滤液，这些患者可以从更长的停留时间中受益，而潜在的潜力较小的患者不会受益于更长的停留时间。对于每个腹膜透析治疗结果，观察到最佳或高峰时间，例如超滤液体积率，尿素清除率（Kt / V）和肌酐清除率，同时使烃吸收最小化。这些值和输入参数可用于定制每个患者的腹膜透析停留时间，估计将为每位患者产生最佳治疗结果的峰值停留时间。

10. 发明申请

US20150082867A1 PERITONEAL DIALYSIS MACHINE 审中-公开
标题翻译：透气机
公开(公告)号：US20150082867A1
公开(公告)日：2015-03-26
申请号：US14553104
申请日：2014-11-25
申请人： Baxter International Inc. , Baxter Healthcare S.A.
发明人： Robert W. Childers
IPC分类号： A61M1/28 , G01L7/00 , G01M3/04 , A61M1/36
CPC分类号： A61M1/284 , A61B5/02042 , A61M1/28 , A61M1/281 , A61M1/288 , A61M1/3621 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3644 , A61M1/3652 , A61M2205/122 , A61M2205/128 , A61M2205/70 , G01L7/00 , G01M3/04
摘要： A method for operating a dialysis cassette including a flexible membrane that covers a pump chamber includes allowing a source of fluid to fluidly communicate with the pump chamber of the dialysis cassette, filling the pump chamber with the fluid from the source, mechanically extending the flexible membrane into the pump chamber with a piston head to expel the fluid from the pump chamber through a flow path, and directly sensing a pressure of the fluid flowing through the flow path at a location of the dialysis cassette adjacent to the pump chamber and using the sensed pressure to perform a test prior to delivering fluid to a patient.
摘要翻译：用于操作包括覆盖泵室的柔性膜的透析盒的方法包括允许流体源与透析盒的泵室流体连通，用来自源的流体填充泵室，将柔性膜机械地延伸进入具有活塞头的泵室，以通过流动路径将流体从泵室排出，并且在与泵室相邻的透析盒的位置处直接感测流过流路的流体的压力，并使用感测到的在向患者输送流体之前执行测试的压力。

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