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1. 发明申请

US20110093059A1 HYBRID STENT WITH HELICAL CONNECTORS 有权
标题翻译：具有螺旋连接器的混合支架
公开(公告)号：US20110093059A1
公开(公告)日：2011-04-21
申请号：US12582251
申请日：2009-10-20
申请人： DAVID R. FISCHELL , ROBERT E. FISCHELL , RAJESH KALAVALAPALLY , WILLIAM A. EASTERBROOK, III
发明人： DAVID R. FISCHELL , ROBERT E. FISCHELL , RAJESH KALAVALAPALLY , WILLIAM A. EASTERBROOK, III
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91541 , A61F2002/91575 , A61F2230/0013
摘要： The present invention is a hybrid stent design using half-slot circumferential sets of strut members with short (
摘要翻译：本发明是使用具有短（<1.5mm）狭缝长度的半槽周向组的支柱构件的混合支架设计，其具有最小的鱼鳞和优异的支架保持力和柔性。这些半槽圆周组的支柱构件通过类似于Palmaz支架的螺旋形连接器彼此连接。本发明的支架设计中的一个重要区别在于，螺旋连接器附接到每隔一个冠部（而不是连接到每个冠部），以进一步改善支架的灵活性。通过适当地改变连接和未连接的弯曲冠的支柱宽度在中心处比在其端部处更大，对于给定的最大应变，可以提供增加的径向强度，当其被扩展到其最大值时直径。

2. 发明申请

US20110270101A1 IMPLANTABLE CARDIAC EVENT DETECTION DEVICE WITH AN ADAPTIVE SLEEP STATE 有权
标题翻译：具有自适应睡眠状态的可植入心脏事件检测装置
公开(公告)号：US20110270101A1
公开(公告)日：2011-11-03
申请号：US13177685
申请日：2011-07-07
申请人： DAVID R. FISCHELL , JONATHAN HARWOOD , ROBERT E. FISCHELL , STEVEN R. JOHNSON
发明人： DAVID R. FISCHELL , JONATHAN HARWOOD , ROBERT E. FISCHELL , STEVEN R. JOHNSON
IPC分类号： A61B5/04
CPC分类号： A61B5/02455 , A61B5/0031 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/746 , A61B5/7465 , A61B2560/0209
摘要： Disclosed is a system for the detection of cardiac events (a guardian system) that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using one or more detection algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the guardian system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means). If the guardian system is put into a pacemaker, the algorithm can utilize a different analysis of the electrogram depending on whether or not the pacemaker is actually pacing the heart.
摘要翻译：公开了一种用于检测心脏事件（监护系统）的系统，其包括称为心脏切除器的植入装置，医师编程器和外部警报系统。该系统旨在提供心脏事件的早期检测，例如由心率增加或运动引起的急性心肌梗死或运动诱发的心肌缺血。如果检测到心律失常，该系统还可以警告患者不太紧急的警报。使用一个或多个检测算法，心脏扫描器可以检测患者的电描记图中的变化，其指示在发生后五分钟内的心脏事件，然后自动向患者发出事件发生。为了提供此警告，监护系统包括在心脏保护器内和/或外部报警系统（外部报警装置）内的内部报警子系统（内部报警装置）。如果将监护人系统放入心脏起搏器，该算法可以根据起搏器是否实际起搏心脏，对电图进行不同的分析。

3. 发明申请

US20120215089A1 PHYSICIAN'S PROGRAMMER WITH ST-SEGMENT HISTOGRAM DISPLAY CAPABILITY 有权
标题翻译：具有ST分段组织显示能力的PHYSICIAN的编程器
公开(公告)号：US20120215089A1
公开(公告)日：2012-08-23
申请号：US13461100
申请日：2012-05-01
申请人： DAVID R. FISCHELL , ROBERT E. FISCHELL , JONATHAN HARWOOD , STEVEN R. JOHNSON
发明人： DAVID R. FISCHELL , ROBERT E. FISCHELL , JONATHAN HARWOOD , STEVEN R. JOHNSON
IPC分类号： A61B5/0452 , A61B5/044
CPC分类号： A61B5/0472 , A61B5/0006 , A61B5/0031 , A61B5/02405 , A61B5/02455 , A61B5/04012 , A61B5/042 , A61B5/0432 , A61B5/044 , A61B5/0452 , A61B5/413 , A61B5/686 , A61B5/746 , A61N1/025 , A61N1/37211 , A61N1/37247
摘要： A physician's programmer for an implantable device is disclosed. The programmer includes a receiver for receiving wireless transmission data from the implantable heart monitor. A processor is configured to extract from the wireless transmission data ST-deviation histogram data as a function of heart rate. The histogram data for a particular heart rate range is shown on a display in the form of a bar chart. The histogram data for a plurality of heart rate ranges is shown in the form of a chart with multiple line plots.
摘要翻译：公开了一种用于可植入装置的医师编程器。编程器包括用于从可植入心脏监视器接收无线传输数据的接收器。处理器被配置为从无线传输数据提取作为心率的函数的ST偏差直方图数据。特定心率范围的直方图数据以条形图的形式显示在显示器上。多个心率范围的直方图数据以具有多个线图的图表的形式示出。

4. 发明申请

US20120215174A1 INTRODUCER SHEATH WITH THIN-WALLED SHAFT AND IMPROVED MEANS FOR ATTACHMENT TO THE SKIN 有权
标题翻译：介绍带有薄壁纱线的鞋子和改善与皮肤接触的手段
公开(公告)号：US20120215174A1
公开(公告)日：2012-08-23
申请号：US13032876
申请日：2011-02-23
申请人： ROBERT E. FISCHELL , TIM A. FISCHELL , DAVID R. FISCHELL , SCOTT J.S. FISCHELL
发明人： ROBERT E. FISCHELL , TIM A. FISCHELL , DAVID R. FISCHELL , SCOTT J.S. FISCHELL
IPC分类号： A61M25/02 , A61M25/01
CPC分类号： A61M25/0662 , A61M5/1418 , A61M25/005 , A61M25/0108 , A61M25/02 , A61M2025/0266 , A61M2025/028 , A61M2025/0286 , A61M2209/088
摘要： An introducer sheath for placement into the vascular system of a human subject. The introducer sheath has a tubular shaft, a side arm, and a hemostasis valve with an integrated attachment mechanism for attaching and detaching a proximal end of the introducer sheath to and from the skin of the human subject.
摘要翻译：用于放置在人类受试者的血管系统中的导引鞘。引导器护套具有管状轴，侧臂和具有集成附接机构的止血阀，用于将引导器护套的近端附接到人类受试者的皮肤和从皮肤脱离皮肤。

5. 发明申请

US20110137194A1 RR INTERVAL BASED BEAT REJECTION FOR A CARDIAC MONITOR 审中-公开
标题翻译：基于区间监控的RR间隔BEAT拒绝
公开(公告)号：US20110137194A1
公开(公告)日：2011-06-09
申请号：US13025476
申请日：2011-02-11
申请人： DAVID R. FISCHELL , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell
发明人： DAVID R. FISCHELL , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell
IPC分类号： A61B5/0456
CPC分类号： A61B5/02455 , A61B5/0031 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/746 , A61B5/7465 , A61B2560/0209
摘要： Disclosed is a system for the detection of cardiac events (a guardian system) that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using one or more detection algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the guardian system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means). If the guardian system is put into a pacemaker, the algorithm can utilize a different analysis of the electrogram depending on whether or not the pacemaker is actually pacing the heart.
摘要翻译：公开了一种用于检测心脏事件（监护系统）的系统，其包括称为心脏切除器的植入装置，医师编程器和外部警报系统。该系统旨在提供心脏事件的早期检测，例如由心率增加或运动引起的急性心肌梗死或运动诱发的心肌缺血。如果检测到心律失常，该系统还可以警告患者不太紧急的警报。使用一个或多个检测算法，心脏扫描器可以检测患者的电描记图中的变化，其指示在发生后五分钟内的心脏事件，然后自动向患者发出事件发生。为了提供此警告，监护系统包括在心脏保护器内和/或外部报警系统（外部报警装置）内的内部报警子系统（内部报警装置）。如果将监护人系统放入心脏起搏器，该算法可以根据起搏器是否实际起搏心脏，对电图进行不同的分析。

6. 发明申请

US20110301684A1 SYSTEM AND METHOD FOR PERFORMING ANGIOGRAPHY AND STENTING 审中-公开
标题翻译：系统和方法进行姿态和姿态
公开(公告)号：US20110301684A1
公开(公告)日：2011-12-08
申请号：US12795707
申请日：2010-06-08
申请人： ROBERT E. FISCHELL , DAVID R. FISCHELL , TIM A. FISCHELL
发明人： ROBERT E. FISCHELL , DAVID R. FISCHELL , TIM A. FISCHELL
IPC分类号： A61M25/00 , A61F2/84
CPC分类号： A61M25/0662 , A61F2/95 , A61M25/0041 , A61M25/0097 , A61M29/00 , A61M2025/0004 , A61M2025/0006 , A61M2025/0681
摘要： An integrated catheter system for performing angiography on a human patient, the integrated catheter system consisting of an angiographic catheter onto which a thin-walled sheath is co-axially mounted. The angiographic catheter having an essentially straight and elongated proximal section in the form of a cylindrical shaft that is surrounded for less than one-half of its length by the thin-walled sheath that has an outer diameter that is less than 0.25 mm greater than the outside diameter of the angiography catheter. The strength to prevent buckling of the thin-walled sheath being provided by the shaft of the angiographic catheter. The integrated catheter system also being ideal for the placement of stents using small diameter stent delivery systems such as the stent-on-a-wire system.
摘要翻译：一种用于对人类患者执行血管造影的集成导管系统，由血管造影导管组成的整体导管系统，薄壁鞘同轴安装在该血管造影导管上。血管造影导管具有圆柱形轴的基本上直的和细长的近端部分，其通过薄壁护套被围绕其长度小于其长度的一半，外壳的外径小于血管造影导管的外径。防止由血管造影导管的轴提供的薄壁鞘的屈曲的强度。集成的导管系统也是使用小直径支架输送系统（如支架在线系统）放置支架的理想选择。

7. 发明申请

US20080183091A1 CARDIAC EVENT CATEGORIZATION SYSTEM 有权
标题翻译： CARDIAC活动分类系统
公开(公告)号：US20080183091A1
公开(公告)日：2008-07-31
申请号：US12059146
申请日：2008-03-31
申请人： ROBERT E. FISCHELL , DAVID R. FISCHELL , TIM A. FISCHELL , SCOTT J.S. FISCHELL
发明人： ROBERT E. FISCHELL , DAVID R. FISCHELL , TIM A. FISCHELL , SCOTT J.S. FISCHELL
IPC分类号： A61B5/0402
CPC分类号： A61L27/54 , A61L2300/236 , A61L2300/254 , A61L2300/42
摘要： Disclosed are methods for detecting an acute myocardial infarction (i.e., a heart attack) at the earliest possible time and promptly warning the patient that he should immediately seek medical care. The present invention includes an implantable electronic system that can sense a change in the patient's electrogram that is indicative of a heart attack. If a heart attack is sensed, the device would then cause an implantable and/or externally located alarm to be actuated to warn the patient of his condition and a medical practitioner at a remote diagnostic center would receive the patient's electrogram for analysis. The patient or a caretaker would then be informed to self-inject medication through a subcutaneous, pass-through drug port that can be a separate device or integrated into the implanted device that is designed for the early detection of a heart attack. The methods of the present invention include determining if a human patient is likely to have a heart attack and, if he is, then implanting within that patient a device that can sense when a heart attack occurs and alarm the patient to take appropriate actions if a heart attack does occur.
摘要翻译：公开了在早期检测急性心肌梗塞（即心脏病发作）的方法，并且及时警告患者他应该立即求医。本发明包括可以感测指示心脏病发作的患者电描记图变化的可植入电子系统。如果感测到心脏病发作，则该装置然后将致动可植入和/或外部定位的警报器，以警告患者其状况，并且远程诊断中心的医务人员将接收患者的电描记图以进行分析。然后将患者或看守者通知皮下，通过的药物口，自动注射药物，该药物口可以是单独的装置，或者整合到被设计用于早期发现心脏病发作的植入装置中。本发明的方法包括确定人类患者是否可能患有心脏病发作，并且如果他是，则在患者体内植入可以感测发生心脏病发作的装置，并且如果心脏病发作确实发生。

8. 发明申请

US20110125041A1 ISCHEMIA MONITORING SYSTEM FOR PATIENTS HAVING PERIODS OF LEFT BUNDLE BRANCH BLOCK 有权
标题翻译： ISCHEMIA监测系统，用于患有左侧支架区段的患者
公开(公告)号：US20110125041A1
公开(公告)日：2011-05-26
申请号：US12791327
申请日：2010-06-01
申请人： DAVID R. FISCHELL , BRUCE HOPENFELD , MICHAEL SASHA JOHN , DAVID KEENAN
发明人： DAVID R. FISCHELL , BRUCE HOPENFELD , MICHAEL SASHA JOHN , DAVID KEENAN
IPC分类号： A61B5/0452
CPC分类号： A61B5/04525 , A61B5/0031 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/1112 , A61N1/365
摘要： A device for detecting cardiac ischemia is disclosed. The device includes a processor that is configured to distinguish between two different heart beats types such as left bundle branch block beats and normal sinus beats. The processor applies different ischemia tests to the two different beat types, and generates alert when it detects ischemia.
摘要翻译：公开了一种用于检测心脏缺血的装置。该装置包括处理器，其被配置为区分两种不同的心跳类型，例如左束支阻滞搏动和正常窦搏动。处理器对两种不同的节拍类型应用不同的缺血试验，并在检测到缺血时产生警报。

9. 发明申请

US20070213600A1 MEDICAL ALARM AND COMMUNICATION SYSTEM AND METHODS 有权
标题翻译：医疗报警与通信系统与方法
公开(公告)号：US20070213600A1
公开(公告)日：2007-09-13
申请号：US11684801
申请日：2007-03-12
申请人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
发明人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
IPC分类号： A61B5/00
CPC分类号： A61B5/04 , A61B5/0031 , A61B5/02028 , A61B5/7264 , A61B2560/0295 , A61N1/08 , G06F19/00 , G06F19/3418 , Y10S128/903
摘要： A medical alarm communications system comprises a pager like device to be kept near a patient. The pager like device communicates medical alerts regarding the patient to a remote central station, which can provide therapeutic and/or diagnostic assistance by communicating to the pager like device. When the pager like device determines that an alert should be sent to the central station, it attempts to establish communication with the central station according to a primary communication protocol. If this attempt is unsuccessful according to some predetermined criteria (e.g. too much time has elapsed before communication is established), then the pager like device generates a message to the patient indicative of the failure, and The attempts to establish communication with the central station according to a secondary communication protocol.
摘要翻译：医疗报警通信系统包括要保持在患者附近的寻呼机装置。寻呼机设备将关于患者的医疗警报传达到远程中心站，其可以通过与寻呼机类设备通信来提供治疗和/或诊断辅助。当寻呼机设备确定警报应发送到中心站时，它尝试根据主要通信协议与中心站建立通信。如果根据某些预定标准（例如在建立通信之前经过了太多时间），则该尝试不成功，那么寻呼机类设备就向患者生成指示故障的消息，并且尝试与中心站建立通信到次要通信协议。

10. 发明申请

US20130053821A1 EXPANDABLE CATHETER SYSTEM FOR VESSEL WALL INJECTION AND MUSCLE AND NERVE FIBER ABLATION 有权
标题翻译：用于船舶注射和肌肉和神经纤维的膨胀导管系统
公开(公告)号：US20130053821A1
公开(公告)日：2013-02-28
申请号：US13216495
申请日：2011-08-24
申请人： DAVID R. FISCHELL , TIM A. FISCHELL
发明人： DAVID R. FISCHELL , TIM A. FISCHELL
IPC分类号： A61M25/10
CPC分类号： A61M25/0662 , A61B5/6848 , A61M25/0084 , A61M25/0097 , A61M2025/0086 , A61M2025/0681
摘要： A vascular nerve ablation (denervation) system includes a multiplicity of expandable needles which open around a central axis to engage the wall of a blood vessel allowing the injection of a cytotoxic or neurotoxic solution for ablating conducting tissue in and near the vessel wall of a renal artery or pulmonary vein. The expandable needles are formed of self-expanding materials and include structures which limit the distance of penetration of the injection needles into the tissue of the wall of the blood vessel.
摘要翻译：血管神经消融（去神经支配）系统包括多个可展开的针，其围绕中心轴线开放以接合血管壁，允许注射细胞毒性或神经毒性溶液以消除肾脏血管壁内和附近的传导组织动脉或肺静脉。可膨胀针由自膨胀材料形成，并且包括限制注射针穿入血管壁组织的距离的结构。

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