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1. 发明申请

US20110125041A1 ISCHEMIA MONITORING SYSTEM FOR PATIENTS HAVING PERIODS OF LEFT BUNDLE BRANCH BLOCK 有权
标题翻译： ISCHEMIA监测系统，用于患有左侧支架区段的患者
公开(公告)号：US20110125041A1
公开(公告)日：2011-05-26
申请号：US12791327
申请日：2010-06-01
申请人： DAVID R. FISCHELL , BRUCE HOPENFELD , MICHAEL SASHA JOHN , DAVID KEENAN
发明人： DAVID R. FISCHELL , BRUCE HOPENFELD , MICHAEL SASHA JOHN , DAVID KEENAN
IPC分类号： A61B5/0452
CPC分类号： A61B5/04525 , A61B5/0031 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/1112 , A61N1/365
摘要： A device for detecting cardiac ischemia is disclosed. The device includes a processor that is configured to distinguish between two different heart beats types such as left bundle branch block beats and normal sinus beats. The processor applies different ischemia tests to the two different beat types, and generates alert when it detects ischemia.
摘要翻译：公开了一种用于检测心脏缺血的装置。该装置包括处理器，其被配置为区分两种不同的心跳类型，例如左束支阻滞搏动和正常窦搏动。处理器对两种不同的节拍类型应用不同的缺血试验，并在检测到缺血时产生警报。

2. 发明申请

US20070213600A1 MEDICAL ALARM AND COMMUNICATION SYSTEM AND METHODS 有权
标题翻译：医疗报警与通信系统与方法
公开(公告)号：US20070213600A1
公开(公告)日：2007-09-13
申请号：US11684801
申请日：2007-03-12
申请人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
发明人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
IPC分类号： A61B5/00
CPC分类号： A61B5/04 , A61B5/0031 , A61B5/02028 , A61B5/7264 , A61B2560/0295 , A61N1/08 , G06F19/00 , G06F19/3418 , Y10S128/903
摘要： A medical alarm communications system comprises a pager like device to be kept near a patient. The pager like device communicates medical alerts regarding the patient to a remote central station, which can provide therapeutic and/or diagnostic assistance by communicating to the pager like device. When the pager like device determines that an alert should be sent to the central station, it attempts to establish communication with the central station according to a primary communication protocol. If this attempt is unsuccessful according to some predetermined criteria (e.g. too much time has elapsed before communication is established), then the pager like device generates a message to the patient indicative of the failure, and The attempts to establish communication with the central station according to a secondary communication protocol.
摘要翻译：医疗报警通信系统包括要保持在患者附近的寻呼机装置。寻呼机设备将关于患者的医疗警报传达到远程中心站，其可以通过与寻呼机类设备通信来提供治疗和/或诊断辅助。当寻呼机设备确定警报应发送到中心站时，它尝试根据主要通信协议与中心站建立通信。如果根据某些预定标准（例如在建立通信之前经过了太多时间），则该尝试不成功，那么寻呼机类设备就向患者生成指示故障的消息，并且尝试与中心站建立通信到次要通信协议。

3. 发明申请

US20110260855A1 MANAGEMENT OF CARDIAC DATA TRANSMISSIONS 审中-公开
标题翻译：心脏数据传输管理
公开(公告)号：US20110260855A1
公开(公告)日：2011-10-27
申请号：US13175187
申请日：2011-07-01
申请人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
发明人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
IPC分类号： G08B1/08
CPC分类号： A61B5/04 , A61B5/0031 , A61B5/02028 , A61B5/7264 , A61B2560/0295 , A61N1/08 , G06F19/3418 , Y10S128/903
摘要： A medical alarm communications system comprises a pager like device to be kept near a patient. The pager like device communicates medical alerts regarding the patient to a remote central station, which can provide therapeutic and/or diagnostic assistance by communicating to the pager like device. When the pager like device determines that an alert should be sent to the central station, it attempts to establish communication with the central station according to a primary communication protocol. If this attempt is unsuccessful according to some predetermined criteria (e.g. too much time has elapsed before communication is established), then the pager like device generates a message to the patient indicative of the failure, and The attempts to establish communication with the central station according to a secondary communication protocol.
摘要翻译：医疗报警通信系统包括要保持在患者附近的寻呼机装置。寻呼机设备将关于患者的医疗警报传达到远程中心站，其可以通过与寻呼机类设备通信来提供治疗和/或诊断辅助。当寻呼机设备确定警报应发送到中心站时，它尝试根据主要通信协议与中心站建立通信。如果根据某些预定标准（例如在建立通信之前经过了太多时间），则该尝试不成功，那么寻呼机类设备就向患者生成指示故障的消息，并且尝试与中心站建立通信到次要通信协议。

4. 发明申请

US20080167701A1 ADAPTIVE CONDUCTIVE LEAD SYSTEMS 失效
标题翻译：自适应导电系统
公开(公告)号：US20080167701A1
公开(公告)日：2008-07-10
申请号：US11970781
申请日：2008-01-08
申请人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
发明人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/086
摘要： The invention describes fluid-based lead systems. The fluid-based leads may be used for sensing from, and stimulating of, human tissue. The fluid-based leads can be used to transfer signals between two locations. The fluid-based leads offer advantages when communicating signals along their length since the leads may be safely used in magnetic environments and offer increased elastic characteristics which are less prone to breakage. The leads can be used externally or with implantable devices, such as those used to monitor, and deliver therapy during the treatment of medical disorders such as cardiac and neurological disorders.
摘要翻译：本发明描述了基于流体的铅系统。基于流体的引线可用于感测和刺激人体组织。基于流体的引线可用于在两个位置之间传输信号。当基于流体的导线沿着它们的长度传递信号时，提供了优点，因为引线可以安全地用于磁性环境中并提供增加的弹性特性，这些特性不容易断裂。引线可以在外部使用，也可以使用可植入的装置，例如用于监测的药物，以及治疗诸如心脏和神经障碍等医学疾病期间的治疗。

5. 发明申请

US20110093059A1 HYBRID STENT WITH HELICAL CONNECTORS 有权
标题翻译：具有螺旋连接器的混合支架
公开(公告)号：US20110093059A1
公开(公告)日：2011-04-21
申请号：US12582251
申请日：2009-10-20
申请人： DAVID R. FISCHELL , ROBERT E. FISCHELL , RAJESH KALAVALAPALLY , WILLIAM A. EASTERBROOK, III
发明人： DAVID R. FISCHELL , ROBERT E. FISCHELL , RAJESH KALAVALAPALLY , WILLIAM A. EASTERBROOK, III
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91541 , A61F2002/91575 , A61F2230/0013
摘要： The present invention is a hybrid stent design using half-slot circumferential sets of strut members with short (
摘要翻译：本发明是使用具有短（<1.5mm）狭缝长度的半槽周向组的支柱构件的混合支架设计，其具有最小的鱼鳞和优异的支架保持力和柔性。这些半槽圆周组的支柱构件通过类似于Palmaz支架的螺旋形连接器彼此连接。本发明的支架设计中的一个重要区别在于，螺旋连接器附接到每隔一个冠部（而不是连接到每个冠部），以进一步改善支架的灵活性。通过适当地改变连接和未连接的弯曲冠的支柱宽度在中心处比在其端部处更大，对于给定的最大应变，可以提供增加的径向强度，当其被扩展到其最大值时直径。

6. 发明申请

US20110270101A1 IMPLANTABLE CARDIAC EVENT DETECTION DEVICE WITH AN ADAPTIVE SLEEP STATE 有权
标题翻译：具有自适应睡眠状态的可植入心脏事件检测装置
公开(公告)号：US20110270101A1
公开(公告)日：2011-11-03
申请号：US13177685
申请日：2011-07-07
申请人： DAVID R. FISCHELL , JONATHAN HARWOOD , ROBERT E. FISCHELL , STEVEN R. JOHNSON
发明人： DAVID R. FISCHELL , JONATHAN HARWOOD , ROBERT E. FISCHELL , STEVEN R. JOHNSON
IPC分类号： A61B5/04
CPC分类号： A61B5/02455 , A61B5/0031 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/746 , A61B5/7465 , A61B2560/0209
摘要： Disclosed is a system for the detection of cardiac events (a guardian system) that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using one or more detection algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the guardian system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means). If the guardian system is put into a pacemaker, the algorithm can utilize a different analysis of the electrogram depending on whether or not the pacemaker is actually pacing the heart.
摘要翻译：公开了一种用于检测心脏事件（监护系统）的系统，其包括称为心脏切除器的植入装置，医师编程器和外部警报系统。该系统旨在提供心脏事件的早期检测，例如由心率增加或运动引起的急性心肌梗死或运动诱发的心肌缺血。如果检测到心律失常，该系统还可以警告患者不太紧急的警报。使用一个或多个检测算法，心脏扫描器可以检测患者的电描记图中的变化，其指示在发生后五分钟内的心脏事件，然后自动向患者发出事件发生。为了提供此警告，监护系统包括在心脏保护器内和/或外部报警系统（外部报警装置）内的内部报警子系统（内部报警装置）。如果将监护人系统放入心脏起搏器，该算法可以根据起搏器是否实际起搏心脏，对电图进行不同的分析。

7. 发明申请

US20130053821A1 EXPANDABLE CATHETER SYSTEM FOR VESSEL WALL INJECTION AND MUSCLE AND NERVE FIBER ABLATION 有权
标题翻译：用于船舶注射和肌肉和神经纤维的膨胀导管系统
公开(公告)号：US20130053821A1
公开(公告)日：2013-02-28
申请号：US13216495
申请日：2011-08-24
申请人： DAVID R. FISCHELL , TIM A. FISCHELL
发明人： DAVID R. FISCHELL , TIM A. FISCHELL
IPC分类号： A61M25/10
CPC分类号： A61M25/0662 , A61B5/6848 , A61M25/0084 , A61M25/0097 , A61M2025/0086 , A61M2025/0681
摘要： A vascular nerve ablation (denervation) system includes a multiplicity of expandable needles which open around a central axis to engage the wall of a blood vessel allowing the injection of a cytotoxic or neurotoxic solution for ablating conducting tissue in and near the vessel wall of a renal artery or pulmonary vein. The expandable needles are formed of self-expanding materials and include structures which limit the distance of penetration of the injection needles into the tissue of the wall of the blood vessel.
摘要翻译：血管神经消融（去神经支配）系统包括多个可展开的针，其围绕中心轴线开放以接合血管壁，允许注射细胞毒性或神经毒性溶液以消除肾脏血管壁内和附近的传导组织动脉或肺静脉。可膨胀针由自膨胀材料形成，并且包括限制注射针穿入血管壁组织的距离的结构。

8. 发明申请

US20120271301A1 EXPANDABLE CATHETER SYSTEM FOR PERI-OSTIAL INJECTION AND MUSCLE AND NERVE FIBER ABLATION 有权
标题翻译：膀胱注射和肌肉和神经纤维的放大导管系统
公开(公告)号：US20120271301A1
公开(公告)日：2012-10-25
申请号：US13092363
申请日：2011-04-22
申请人： DAVID R. FISCHELL , TIM A. FISCHELL
发明人： DAVID R. FISCHELL , TIM A. FISCHELL
IPC分类号： A61B18/12
CPC分类号： A61B18/1492 , A61B2018/00214 , A61B2018/0022 , A61B2018/00375 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/143 , A61M5/00
摘要： At the present time, physicians often treat patients with atrial fibrillation (AF) using radiofrequency (RF) catheter systems to ablate conducting tissue in the wall of the Left Atrium of the heart around the ostium of the pulmonary veins. These systems are expensive and take time consuming to use. The present invention circular ablation system CAS includes a multiplicity of expandable needles that can be expanded around a central axis and positioned to inject a fluid like ethanol to ablate conductive tissue in a ring around the ostium of a pulmonary vein quickly and without the need for expensive capital equipment. The expansion of the needles is accomplished by self-expanding or balloon expandable structures. The invention includes centering means so that the needles will be situated in a pattern surrounding the outside of the ostium of a vein. Also included are members that limit the distance of penetration of the needles into the wall of the left atrium. The present invention also has application to ablating tissue around the ostium of a renal artery for the treatment of hypertension.
摘要翻译：目前，医生经常使用射频（RF）导管系统治疗房颤患者，以消融肺静脉周围心脏左心房壁的导电组织。这些系统是昂贵的并且花费耗时的使用。本发明的圆形消融系统CAS包括多个可扩展的针，其可以围绕中心轴线扩张并且被定位成像乙醇一样注入流体，以便快速地在肺静脉的口周围环绕环中的导电组织，而不需要昂贵的资本设备。针的膨胀通过自膨胀或球囊可膨胀结构来实现。本发明包括定心装置，使得针头将位于围绕静脉口的外侧的图案中。还包括限制针头进入左心房壁的距离的成员。本发明还可用于消除肾动脉口周围的组织用于治疗高血压。

9. 发明申请

US20120271277A1 EXPANDABLE CATHETER SYSTEM FOR PERI-OSTIAL INJECTION AND MUSCLE AND NERVE FIBER ABLATION 有权
标题翻译：膀胱注射和肌肉和神经纤维的放大导管系统
公开(公告)号：US20120271277A1
公开(公告)日：2012-10-25
申请号：US13196104
申请日：2011-08-02
申请人： DAVID R. FISCHELL , TIM A. FISCHELL
发明人： DAVID R. FISCHELL , TIM A. FISCHELL
IPC分类号： A61M29/00
CPC分类号： A61B18/06 , A61B5/042 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B2017/22038 , A61B2017/22068 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00285 , A61B2018/00375 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00839 , A61B2018/143 , A61B2018/1475 , A61B2090/3966 , A61M2025/0087
摘要： At the present time, physicians often treat patients with atrial fibrillation (AF) using radiofrequency (RF) catheter systems to ablate conducting tissue in the wall of the Left Atrium of the heart around the ostium of the pulmonary veins. These systems are expensive and take time consuming to use. The present invention circular ablation system CAS includes a multiplicity of expandable needles that can be expanded around a central axis and positioned to inject a fluid like ethanol to ablate conductive tissue in a ring around the ostium of a pulmonary vein quickly and without the need for expensive capital equipment. The expansion of the needles is accomplished by self-expanding or balloon expandable structures. The invention includes centering means so that the needles will be situated in a pattern surrounding the outside of the ostium of a vein. Also included are members that limit the distance of penetration of the needles into the wall of the left atrium, or the aortic wall. The present invention also has an important application to ablate tissue around the ostium of one or both renal arteries, for the ablation of the sympathetic nerve fibers and/or other afferent or efferent nerves going to or from each kidney in order to treat hypertension.
摘要翻译：目前，医生经常使用射频（RF）导管系统治疗房颤患者，以消融肺静脉周围心脏左心房壁的导电组织。这些系统是昂贵的并且花费耗时的使用。本发明的圆形消融系统CAS包括多个可扩展的针，其可以围绕中心轴线扩张并且被定位成像乙醇一样注入流体，以便快速地在肺静脉的口周围环绕环中的导电组织，而不需要昂贵的资本设备。针的膨胀通过自膨胀或球囊可膨胀结构来实现。本发明包括定心装置，使得针头将位于围绕静脉口的外侧的图案中。还包括限制针穿入左心房壁或主动脉壁的距离的构件。本发明还具有重要的应用，用于消除一个或两个肾动脉周围的组织，用于消除去往或来自每个肾脏的交感神经纤维和/或其他传入或传出神经以治疗高血压。

10. 发明申请

US20120215089A1 PHYSICIAN'S PROGRAMMER WITH ST-SEGMENT HISTOGRAM DISPLAY CAPABILITY 有权
标题翻译：具有ST分段组织显示能力的PHYSICIAN的编程器
公开(公告)号：US20120215089A1
公开(公告)日：2012-08-23
申请号：US13461100
申请日：2012-05-01
申请人： DAVID R. FISCHELL , ROBERT E. FISCHELL , JONATHAN HARWOOD , STEVEN R. JOHNSON
发明人： DAVID R. FISCHELL , ROBERT E. FISCHELL , JONATHAN HARWOOD , STEVEN R. JOHNSON
IPC分类号： A61B5/0452 , A61B5/044
CPC分类号： A61B5/0472 , A61B5/0006 , A61B5/0031 , A61B5/02405 , A61B5/02455 , A61B5/04012 , A61B5/042 , A61B5/0432 , A61B5/044 , A61B5/0452 , A61B5/413 , A61B5/686 , A61B5/746 , A61N1/025 , A61N1/37211 , A61N1/37247
摘要： A physician's programmer for an implantable device is disclosed. The programmer includes a receiver for receiving wireless transmission data from the implantable heart monitor. A processor is configured to extract from the wireless transmission data ST-deviation histogram data as a function of heart rate. The histogram data for a particular heart rate range is shown on a display in the form of a bar chart. The histogram data for a plurality of heart rate ranges is shown in the form of a chart with multiple line plots.
摘要翻译：公开了一种用于可植入装置的医师编程器。编程器包括用于从可植入心脏监视器接收无线传输数据的接收器。处理器被配置为从无线传输数据提取作为心率的函数的ST偏差直方图数据。特定心率范围的直方图数据以条形图的形式显示在显示器上。多个心率范围的直方图数据以具有多个线图的图表的形式示出。

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