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1. 发明授权

US07175654B2 Stent design having stent segments which uncouple upon deployment 有权
标题翻译：支架设计具有支架段，在展开后将其脱开
公开(公告)号：US07175654B2
公开(公告)日：2007-02-13
申请号：US10687143
申请日：2003-10-16
申请人： Craig Bonsignore , Kirk Johnson
发明人： Craig Bonsignore , Kirk Johnson
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/852 , A61F2/89 , A61F2/91 , A61F2002/826 , A61F2002/91516 , A61F2002/91533 , A61F2002/91558 , A61F2002/91591 , A61F2230/0054 , A61F2250/0063 , A61F2250/0098
摘要： A stent or other intraluminal medical device may be constructed utilizing multiple, individual, independent, self-expanding stent segments which are designed to interlock when constrained within a delivery sheath and uncouple upon deployment. The individual segments are releasably connected by a series of bridging elements and receptacles.
摘要翻译：支架或其他管腔内医疗装置可以利用多个独立的，独立的自扩张支架段来构造，其被设计成当被限制在输送护套内时互锁，并且在展开时不连接。各个段通过一系列桥接元件和插座可释放地连接。

2. 发明申请

US20050085896A1 Stent design having stent segments which uncouple upon deployment 有权
标题翻译：支架设计具有支架段，在展开后将其脱开
公开(公告)号：US20050085896A1
公开(公告)日：2005-04-21
申请号：US10687143
申请日：2003-10-16
申请人： Craig Bonsignore , Kirk Johnson
发明人： Craig Bonsignore , Kirk Johnson
IPC分类号： A61F2/00 , A61F2/82 , A61F2/06
CPC分类号： A61F2/915 , A61F2/852 , A61F2/89 , A61F2/91 , A61F2002/826 , A61F2002/91516 , A61F2002/91533 , A61F2002/91558 , A61F2002/91591 , A61F2230/0054 , A61F2250/0063 , A61F2250/0098
摘要： A stent or other intraluminal medical device may be constructed utilizing multiple, individual, independent, self-expanding stent segments which are designed to interlock when constrained within a delivery sheath and uncouple upon deployment. The individual segments are releasably connected by a series of bridging elements and receptacles.
摘要翻译：支架或其他管腔内医疗装置可以利用多个独立的，独立的自扩张支架段来构造，其被设计成当被限制在输送护套内时互锁，并且在展开时不连接。各个段通过一系列桥接元件和插座可释放地连接。

3. 发明授权

US10092427B2 Alternating circumferential bridge stent design and methods for use thereof 有权
公开(公告)号：US10092427B2
公开(公告)日：2018-10-09
申请号：US12939894
申请日：2010-11-04
申请人： Craig Bonsignore , Stephen J. Kleshinski
发明人： Craig Bonsignore , Stephen J. Kleshinski
IPC分类号： A61F2/915 , A61F2/04 , A61M1/36
摘要： A stent includes a first section and a second section. The first section and the second section each include a plurality of expandable modules and a plurality of bridging modules. Each expandable module includes a plurality of strut elements that join together at a plurality of apices, and each bridging module includes bridging elements that connect an apex of a first module with an apex of a second module. In some aspects, the first section is more flexible along the longitudinal axis of the stent than the second section and is configured to be placed in a specific region of a vessel that requires flexibility to accommodate surrounding anatomy. In some aspects, the first section is more radially stiff than the second section and is configured to be placed in a specific region of the vessel that requires radial stiffness to counteract crushing force caused by surrounding anatomy.

4. 发明授权

US08142490B2 Stent segments axially connected by thin film 有权
标题翻译：支架用薄膜轴向连接
公开(公告)号：US08142490B2
公开(公告)日：2012-03-27
申请号：US11923308
申请日：2007-10-24
申请人： Carolyn Rice , Craig Bonsignore
发明人： Carolyn Rice , Craig Bonsignore
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/844 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/072 , A61F2002/075 , A61F2220/005 , A61F2220/0058 , A61F2250/0023 , Y10T29/49982 , Y10T29/49995
摘要： In accordance with the present invention, there is provided a stent for insertion into a vessel of a patient. The stent has a front and back open ends and a longitudinal axis extending therebetween. The stent has a plurality of adjacent hoops that are held in alignment with the longitudinal axis between the front and back open ends by a thin film tube. The hoops are attached to either the inner or outer surface of the thin film tube. The stent is compressed into a first smaller diameter for insertion into the vessel with a delivery tube and a second larger diameter for deployment into the vessel. The inventive stent can be retracted into the delivery tube if it is improperly deployed.
摘要翻译：根据本发明，提供一种用于插入患者血管的支架。支架具有前后开口端和在其间延伸的纵向轴线。支架具有多个相邻的箍，其通过薄膜管保持在前开口端和后开口端之间的纵向轴线对准。箍连接到薄膜管的内表面或外表面。支架被压缩成第一较小的直径，以便用输送管插入血管，第二较大的直径用于展开到血管中。如果不适当地展开，本发明的支架可以缩回到输送管中。

5. 发明申请

US20110251674A1 EXPANDABLE SLIDE AND LOCK STENT 有权
标题翻译：可扩展的滑盖和锁杆
公开(公告)号：US20110251674A1
公开(公告)日：2011-10-13
申请号：US13083508
申请日：2011-04-08
申请人： Eric Schmid , Keith Weier , Keith Esser , Steven C. Howard , John Hobson , Craig Bonsignore
发明人： Eric Schmid , Keith Weier , Keith Esser , Steven C. Howard , John Hobson , Craig Bonsignore
IPC分类号： A61F2/82 , B23P11/00
CPC分类号： A61F2/90 , A61F2/844 , A61F2/86 , A61F2/88 , A61F2/885 , A61F2/89 , A61F2/915 , A61F2/92 , A61F2/93 , A61F2002/825 , A61F2002/91591 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , B33Y80/00 , Y10T29/49826
摘要： An expandable slide and lock stent comprises a tubular member that can be expanded from a collapsed state to an expanded state. The tubular member can comprise a reversing helical backbone and at least one rail member extending from the helical backbone in a circumferential direction. The backbone can have at least one engagement element that can be configured to receive a rail member to form the tubular member. In some embodiments, the reversing helical backbone can comprise a plurality of discrete segments having a variable profile and/or wave form.
摘要翻译：可扩张的滑动和锁定支架包括可以从折叠状态扩展到扩张状态的管状构件。管状构件可以包括反向螺旋主干和至少一个轨道构件，其沿圆周方向从螺旋主体延伸。主骨架可以具有至少一个接合元件，该接合元件可被构造成接收轨道构件以形成管状构件。在一些实施例中，反向螺旋骨架可以包括具有可变轮廓和/或波形的多个离散段。

6. 发明授权

US07780714B2 Implant delivery apparatus 有权
标题翻译：植入物输送装置
公开(公告)号：US07780714B2
公开(公告)日：2010-08-24
申请号：US11264586
申请日：2005-11-01
申请人： Clifford Dwyer , Michael V. Williamson, Jr. , Craig Bonsignore
发明人： Clifford Dwyer , Michael V. Williamson, Jr. , Craig Bonsignore
IPC分类号： A61F2/06
CPC分类号： A61M25/0122 , A61F2/95 , A61F2002/9517 , A61F2250/0069
摘要： An apparatus for delivering an implant within a lumen or passageway is provided. The apparatus comprises a flexible, hollow outer member having an elongated section that is inserted into and navigated through the lumen of passageway. The implant is mounted within the distal end of the elongated section. An elongated fluid chamber is defined within the outer member between two valves or seals. The valves or seals permit fluid flow in a pre-determined direction during loading of fluid into the chamber, but prevent fluid to exit the chamber during deployment of the implant. A shaft is in contact with the proximal end of the fluid column. During deployment, the shaft is held in a fixed position and the outer member actuated in a proximal direction. The implant exerts compressive forces on the outer member as it is actuated proximally. These forces are transmitted to the fluid column which resists buckling.
摘要翻译：提供了一种用于将植入物递送在管腔或通道内的装置。该装置包括柔性的中空的外部构件，该外部构件具有插入并通过通道内腔的细长部分。植入物安装在细长部分的远端内。在两个阀或密封件之间的外部构件中限定了细长的流体室。阀或密封件允许流体在流体进入腔室期间以预定的方向流动，但是在植入物展开期间阻止流体离开腔室。轴与流体柱的近端接触。在展开期间，轴保持在固定位置，并且外部构件沿近端方向致动。植入物在近端致动时，在外部构件上施加压缩力。这些力传递到抵抗弯曲的流体柱。

7. 发明申请

US20070073373A1 Intraluminal medical device with nested interlocking segments 有权
标题翻译：具有嵌套互锁段的管腔内医疗装置
公开(公告)号：US20070073373A1
公开(公告)日：2007-03-29
申请号：US11237574
申请日：2005-09-28
申请人： Craig Bonsignore
发明人： Craig Bonsignore
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2/95 , A61F2002/828 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/9155 , A61F2002/91591 , A61F2002/9665 , A61F2250/006
摘要： An intraluminal medical device having nested interlocking axially adjacent segments that remain interlocked during delivery to an intended treatment site. The medical device is preferably a stent in which the nested interlocked axially adjacent segments provide increased control and stability of the stent during delivery and increased vessel support when full deployment is effected. The stent may be a self-expanding stent or a balloon expandable stent. In either case, a series of repeating cells comprise a segment. Each cell comprises a protrusion and a radially and circumferentially adjacent receptacle. The protrusion from at least one cell in a segment interlocks with the receptacle of an axially adjacent segment to form the stent. The protrusions remain coupled with a corresponding receptacle during delivery of the stent to the intended treatment site, and can remain engaged thereafter, or can disengage from the corresponding receptacle after full deployment of the stent is effected. An LID ratio of the expanded length of the stent segment relative to the expanded diameter of the stent is preferably greater than one to enhance stent delivery and maximize fatigue durability of the structure. Radiaopaque markers may be inserted within, integral therewith, or coated thereon ends of the protrusions.
摘要翻译：一种管腔内医疗装置，其具有嵌套的互锁轴向相邻的段，其在递送到预期治疗部位期间保持互锁。医疗装置优选是支架，其中嵌套的互锁轴向相邻的节段在完全展开时在递送期间提供支架的增加的控制和稳定性以及增加的血管支撑。支架可以是自扩张支架或球囊可扩张支架。在任一种情况下，一系列重复的细胞包含一个片段。每个电池包括突起和径向和周向相邻的容器。来自区段中的至少一个细胞的突起与轴向相邻的区段的容器互锁以形成支架。在将支架输送到预期的治疗部位期间，突起保持与相应的容器联接，并且可以在此之后保持接合，或者在完全展开支架之后可以与相应的容器脱离接触。支架段的扩展长度相对于支架的扩大直径的LID比优选大于1以增强支架输送并使结构的疲劳耐久性最大化。镭斑标记可插入其内，与其一体形成，或在其上涂覆突起的端部。

8. 发明授权

US08562666B2 Intraluminal medical device with nested interlocking segments 有权
标题翻译：具有嵌套互锁段的管腔内医疗装置
公开(公告)号：US08562666B2
公开(公告)日：2013-10-22
申请号：US11237574
申请日：2005-09-28
申请人： Craig Bonsignore
发明人： Craig Bonsignore
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2/95 , A61F2002/828 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/9155 , A61F2002/91591 , A61F2002/9665 , A61F2250/006
摘要： The invention is a medical device having nested interlocking axially adjacent segments that remain interlocked during delivery. The medical device is a stent in which the nested interlocked axially adjacent segments provide increased control and stability of the stent during delivery and increased vessel support when deployed. A series of repeating cells comprise a segment. Each cell comprises a protrusion and a radially and circumferentially adjacent receptacle. The protrusion from at least one cell in a segment interlocks with the receptacle of an axially adjacent segment to form the stent. The protrusions remain coupled with a corresponding receptacle during delivery of the stent to the intended treatment site, and can remain engaged thereafter, or can disengage from the corresponding receptacle after full deployment of the stent.
摘要翻译：本发明是一种医疗装置，其具有嵌套的互锁轴向相邻的段，其在递送期间保持互锁。医疗装置是支架，其中嵌套的互锁的轴向相邻的段在递送期间提供支架的增加的控制和稳定性，并且在展开时增加血管支撑。一系列重复细胞包含一段。每个电池包括突起和径向和周向相邻的容器。来自区段中的至少一个细胞的突起与轴向相邻的区段的容器互锁以形成支架。在将支架输送到预期治疗部位期间，突起保持与相应的容器联接，并且可以在此之后保持接合，或者在完全展开支架之后可以与对应的容器脱离接触。

9. 发明授权

US08545547B2 Expandable slide and lock stent 有权
公开(公告)号：US08545547B2
公开(公告)日：2013-10-01
申请号：US13113894
申请日：2011-05-23
申请人： Eric Schmid , Andrew Morris , Keith Weier , Craig Bonsignore , Keith Esser , Steven C. Howard , Joseph A. DiPari
发明人： Eric Schmid , Andrew Morris , Keith Weier , Craig Bonsignore , Keith Esser , Steven C. Howard , Joseph A. DiPari
IPC分类号： A61F2/06
CPC分类号： A61F2/93 , A61F2/92 , A61F2220/0016 , A61F2230/0091 , B33Y80/00
摘要： An expandable slide and lock stent is provided that comprises a plurality of radial elements interconnected to form a tubular member. Each radial element can comprise a helical backbone and at least one elongate member extending from the helical backbone in a circumferential direction. Each backbone can have at least one slot that can be configured to receive an elongate member of an adjacent radial element.

10. 发明授权

US08133268B2 Stent/fiber structural combinations 有权
标题翻译：支架/纤维结构组合
公开(公告)号：US08133268B2
公开(公告)日：2012-03-13
申请号：US11755171
申请日：2007-05-30
申请人： Craig Bonsignore
发明人： Craig Bonsignore
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/88 , A61F2002/9511 , A61F2210/0004 , A61F2230/0054
摘要： A plurality of endoluminal segments axially connected by fiber bridges is disclosed. The endoluminal segments may either be balloon-expandable or self-expanding, with the preferred embodiment being superelastic nitinol. The intraluminal segments may possess a textured surface or at least one geometric feature per segment, preferably located at the apex of a strut pair comprising the intraluminal segment, preferably capable of serving as an anchoring point for the fiber bridges. These geometric features may transmit axially compressive loads during deployment from a device such as a catheter, and may further be capable of interlocking the endoluminal segments when constrained within a device such as a catheter. The fibers comprising the bridges may be polymeric, silk, collagen, bioabsorbable, or a blend thereof. The fiber network comprising the bridges may be regularly oriented, randomly oriented, localized, or continuous. Moreover, the intraluminal segments and fiber bridges may be individually impregnated with therapeutic material, or may both be impregnated with therapeutic material.
摘要翻译：公开了通过光纤桥轴向连接的多个腔内节段。腔内节段可以是球囊可膨胀的或自膨胀的，优选的实施方案是超弹性镍钛诺。腔内节段可以具有纹理表面或每个节段至少一个几何特征，优选地位于包括腔内节段的支柱对的顶点处，优选地能够用作纤维桥的锚定点。这些几何特征可以在从诸如导管的装置展开期间传递轴向压缩载荷，并且还可以在被限制在诸如导管的装置内时将腔内节段互锁。包含桥的纤维可以是聚合物，丝，胶原，生物可吸收的或其混合物。包括桥的光纤网络可以是规则定向的，随机取向的，局部的或连续的。此外，管腔内节段和纤维桥可以单独地用治疗材料浸渍，或者都可以用治疗材料浸渍。

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