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1. 发明授权

US06773446B1 Delivery apparatus for a self-expanding stent 有权
标题翻译：用于自扩张支架的输送装置
公开(公告)号：US06773446B1
公开(公告)日：2004-08-10
申请号：US09631026
申请日：2000-08-02
申请人： Clifford J. Dwyer , Luis A. Davila , Frederick Feller, III , Mark L. Mathis , David J. Wilson
发明人： Clifford J. Dwyer , Luis A. Davila , Frederick Feller, III , Mark L. Mathis , David J. Wilson
IPC分类号： A61M2900
CPC分类号： A61F2/95 , A61F2/958 , A61F2/966
摘要： A delivery apparatus for a self-expanding stent is disclosed. The apparatus has an outer sheath forming an elongated tubular member having distal and proximal ends and an inside and outside diameter. The apparatus also includes an inner shaft located coaxially within the outer sheath. The inner shaft has a distal end, a proximal end and longitudinal axis extending therebetween. At least a portion of the inner shaft is made from a flexible coiled member. The shaft preferably includes a stop attached thereto, the stop being proximal to the distal end of the sheath. Lastly, the apparatus includes a self-expanding stent located within the outer sheath, wherein the stent makes frictional contact with the outer sheath and the shaft is disposed coaxially within a lumen of the stent. During deployment of the stent, the stent makes contact with the stop.
摘要翻译：公开了一种用于自扩张支架的输送装置。该装置具有形成具有远端和近端以及内径和外径的细长管状构件的外护套。该装置还包括同轴地位于外护套内的内轴。内轴具有在其间延伸的远端，近端和纵向轴线。内轴的至少一部分由柔性卷绕构件制成。轴优选地包括附接到其上的止动件，止动件靠近护套的远端。最后，该装置包括位于外护套内的自扩张支架，其中支架与外护套摩擦接触，并且轴同轴地设置在支架内腔内。在展开支架期间，支架与止动器接触。

2. 发明授权

US06743219B1 Delivery apparatus for a self-expanding stent 有权
标题翻译：用于自扩张支架的输送装置
公开(公告)号：US06743219B1
公开(公告)日：2004-06-01
申请号：US09631002
申请日：2000-08-02
申请人： Clifford J. Dwyer , Luis A. Davila , Frederick Feller, III , Mark L. Mathis , David J. Wilson
发明人： Clifford J. Dwyer , Luis A. Davila , Frederick Feller, III , Mark L. Mathis , David J. Wilson
IPC分类号： A61M2500
CPC分类号： A61F2/95 , A61F2/958 , A61F2/966
摘要： A delivery apparatus for self-expanding stents may be utilized to safely deliver stents to a target site. The apparatus has an outer sheath forming an elongated tubular member having distal and proximal ends and an inside and outside diameter. The apparatus also includes an inner shaft located coaxially within the outer sheath. The inner shaft has a distal end, a proximal end and a longitudinal axis extending therebetween. At least a portion of the inner shaft is made from a flexible coiled member. The shaft preferably includes a stop attached thereto, the stop being proximal to the distal end of the sheath. Lastly, the apparatus includes a self-expanding stent located within the outer sheath, wherein the stent makes frictional contact with the outer sheath and the shaft is disposed coaxially within a lumen of the stent. During deployment of the stent, the stent makes contact with the stop.
摘要翻译：用于自扩张支架的输送装置可用于将支架安全地输送到目标部位。该装置具有形成具有远端和近端以及内径和外径的细长管状构件的外护套。该装置还包括同轴地位于外护套内的内轴。内轴具有远端，近端和在其间延伸的纵向轴线。内轴的至少一部分由柔性卷绕构件制成。轴优选地包括附接到其上的止动件，止动件靠近护套的远端。最后，该装置包括位于外护套内的自扩张支架，其中支架与外护套摩擦接触，并且轴同轴地设置在支架内腔内。在展开支架期间，支架与止动器接触。

3. 发明授权

US06425898B1 Delivery apparatus for a self-expanding stent 有权
标题翻译：用于自扩张支架的输送装置
公开(公告)号：US06425898B1
公开(公告)日：2002-07-30
申请号：US09243750
申请日：1999-02-03
申请人： David J. Wilson , Frederick Feller, III , Luis A. Davila , Stephen J. Querns , Kirk L. Johnson
发明人： David J. Wilson , Frederick Feller, III , Luis A. Davila , Stephen J. Querns , Kirk L. Johnson
IPC分类号： A61F1100
CPC分类号： A61F2/95 , A61F2/91 , A61F2/958 , A61F2/966
摘要： In accordance with the present invention there is provided a delivery apparatus for a self-expanding stent. The apparatus has an outer sheath which is an elongated tubular member with distal and proximal ends and inside and outside diameters. The outer sheath has an enlarged section adjacent its distal end. The enlarged section has a greater inside and outside diameter than the inside and outside diameter of the sheath proximal to the enlarged section. The apparatus also includes an inner shaft located coaxially within the outer sheath. The shaft has a distal end and a proximal end. The shaft further includes a stop attached thereto which is proximal to the distal end of the sheath. Lastly, the apparatus includes a self-expanding stent located within the enlarged section of the outer sheath and makes frictional contact with the outer sheath. The shaft is disposed coaxially within a lumen of the stent, whereby the stent makes contact with the stop during deployment.
摘要翻译：根据本发明，提供了一种用于自扩张支架的输送装置。该装置具有外鞘，该外鞘是具有远端和近端以及内径和外径的细长管状构件。外鞘具有与其远端相邻的放大部分。扩大部分具有比靠近放大部分的鞘的内部和外部直径更大的内部和外部直径。该装置还包括同轴地位于外护套内的内轴。轴具有远端和近端。轴还包括附接到其上的止动件，该止动件靠近护套的远端。最后，该装置包括位于外护套的扩大部分内并与外护套摩擦接触的自扩张支架。轴同轴地布置在支架的内腔中，由此支架在展开期间与止动件接触。

4. 发明申请

US20080051867A1 Multiple in vivo implant delivery device 审中-公开
标题翻译：多个体内植入物输送装置
公开(公告)号：US20080051867A1
公开(公告)日：2008-02-28
申请号：US11511097
申请日：2006-08-28
申请人： Luis A. Davila , Clifford J. Dwyer
发明人： Luis A. Davila , Clifford J. Dwyer
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2002/826 , A61F2250/0098
摘要： A delivery catheter for providing the percutaneous delivery of a plurality of vascular stents. One or more stops are provided in the delivery catheter between each of the plurality of stents. The stops be radiopaque to assist in deploying the stents at desired locations within the vasculature of a patient.
摘要翻译：用于提供多个血管支架的经皮输送的输送导管。在所述多个支架中的每一个之间的输送导管中设置有一个或多个止挡件。停止点是不透射线的，以帮助将支架部署在病人脉管系统内的所需位置。

5. 发明授权

US07056550B2 Medical devices, drug coatings and methods for maintaining the drug coatings thereon 有权
公开(公告)号：US07056550B2
公开(公告)日：2006-06-06
申请号：US10636435
申请日：2003-08-07
申请人： Luis A. Davila , David Christian Lentz , Gerard H. Llanos , Jorge Orlando Mendez , Pallassana V. Narayanan , Alan Roy Pelton , Mark B. Roller , Karl K. Scheidt , Angelo George Scopelianos , William Douglas Shaw, Jr. , James H. Silver , John Spaltro , Christine Trepanier , David J. Wilson
发明人： Luis A. Davila , David Christian Lentz , Gerard H. Llanos , Jorge Orlando Mendez , Pallassana V. Narayanan , Alan Roy Pelton , Mark B. Roller , Karl K. Scheidt , Angelo George Scopelianos , William Douglas Shaw, Jr. , James H. Silver , John Spaltro , Christine Trepanier , David J. Wilson
IPC分类号： B05D1/36 , B05D3/02
CPC分类号： A61F2/91 , A61B17/00491 , A61B17/0469 , A61B17/0644 , A61B17/11 , A61B17/115 , A61B2017/06028 , A61F2/064 , A61F2/915 , A61F2002/3008 , A61F2002/91533 , A61F2002/91558 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0067 , A61F2250/0098 , A61F2310/0097 , A61F2310/00976 , A61K31/436 , A61K31/727 , A61K45/06 , A61L17/145 , A61L27/34 , A61L29/085 , A61L31/022 , A61L31/10 , A61L31/16 , A61L31/18 , A61L2300/416 , A61L2300/608 , A61L2420/02 , B05D1/18 , B05D3/0254 , B05D3/0493 , A61K2300/00 , C08L27/20 , C08L27/16 , C08L27/14 , C08L27/12
摘要： Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.

6. 发明授权

US06863685B2 Radiopacity intraluminal medical device 有权
标题翻译：无线电管腔内医疗器械
公开(公告)号：US06863685B2
公开(公告)日：2005-03-08
申请号：US09884729
申请日：2001-06-19
申请人： Luis A. Davila , Jorge Orlando Mendez , Alan R. Pelton , Karl K. Scheidt , William D. Shaw, Jr. , James Silver , Christine Trepanier , David J. Wilson
发明人： Luis A. Davila , Jorge Orlando Mendez , Alan R. Pelton , Karl K. Scheidt , William D. Shaw, Jr. , James Silver , Christine Trepanier , David J. Wilson
IPC分类号： A61F2/84 , A61F2/00 , A61F2/06 , A61F2/90 , A61L31/02 , A61L31/10 , A61L31/18
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2230/005 , A61F2230/0054 , A61F2250/0067 , A61F2250/0068 , A61F2250/0098 , A61F2310/0097 , A61L31/022 , A61L31/10 , A61L31/18 , C08L27/12
摘要： A stent or other intraluminal medical device having markers formed from housings integral with the stent and marker inserts having a higher radiopacity than the stent provides for more precise placement and post-procedural visualization in a vessel, by increasing the radiopacity of the stent under X-ray fluoroscopy. The housings are formed integral to the stent and the marker inserts are made from a material close in the galvanic series to the stent material and sized to substantially minimize the effect of galvanic corrosion.
摘要翻译：支架或其他管腔内医疗装置具有由与支架成一体的外壳和与支架相比具有更高的射线不透性的标记插入物形成的标记，通过增加支架在X射线下的放射不透性，可以在血管中提供更精确的放置和术后可视化，射线透视。壳体与支架一体形成，并且标记插入物由紧邻电镀系列的材料制成到支架材料上，并且尺寸被设计成基本上最小化电偶腐蚀的影响。

7. 发明授权

US5562632A One piece self-aligning, self-lubricating catheter valve 失效
公开(公告)号：US5562632A
公开(公告)日：1996-10-08
申请号：US444217
申请日：1995-05-18
申请人： Luis A. Davila , Carlo R. De La Mata , Stephen J. Querns
发明人： Luis A. Davila , Carlo R. De La Mata , Stephen J. Querns
IPC分类号： A61M39/06 , A61M5/178
CPC分类号： A61M39/0606 , A61M2039/062 , A61M2039/0633 , A61M2039/064 , A61M2039/0653
摘要： An elastomeric valve partition is conventionally mounted on a catheter comprising a tubular catheter body. The valve partition defines a central aperture extending inwardly from one of the faces, only partway through the valve partition. The partition also carries a plurality of radial slits extending from the other of the faces only partway through the valve partition and intersecting the central aperture. The central aperture is of a diameter to closely fit a guidewire extending through the valve partition, while the radial slits have a length that is at least double the radius of the central aperture. The slits preferably rotate circumferentially about 5 to 60 degrees as they extend through the valve partition from one face toward the other. A lubricity enhancing additive is present, selected from the group consisting of bismuth oxychloride, polytetrafluoroethylene, titanium dioxide, graphite, polyethylene wax, polyvinylpyrrolidone, and combinations thereof.

8. 发明授权

US5520655A Catheter hemostasis valve 失效
标题翻译：导管止血阀
公开(公告)号：US5520655A
公开(公告)日：1996-05-28
申请号：US275828
申请日：1994-07-15
申请人： Luis A. Davila , Carlo R. De La Mata
发明人： Luis A. Davila , Carlo R. De La Mata
IPC分类号： A61M39/06 , A61M39/20 , A61M39/26
CPC分类号： A61M39/0606 , A61M2039/0633 , A61M2039/064
摘要： A catheter which carries a hemostasis valve, such as a catheter sheath introducer, carries a slit elastic valve partition as part of the hemostasis valve. The inner housing has a bore and the end cap has an aperture that each communicate with an opposed surface of the valve partition. The diameter of the aperture and the bore are each of a distance that exceeds the outer diameter of preferably a french six catheter extending through the catheter of this invention, plus two times the thickness of the partition. When these conditions are satisfied, larger diameter inner catheters can be slidably inserted and removed through the catheter and valve of this invention with reduced frictional characteristics. Also, a compression ring is provided between the valve partition and the end cap which causes the valve partition to bow outwardly against the end cap and toward the aperture thereof. This, in turn improves the sealing characteristics. Also, an improved slit design for the partition is disclosed.
摘要翻译：携带止血阀（例如导管鞘引入器）的导管携带狭缝弹性瓣膜分隔件作为止血阀的一部分。内壳体具有孔，并且端盖具有孔，每个孔与阀分隔件的相对表面连通。孔和孔的直径各自的距离超过本发明的延伸穿过导管的法兰六导管的外径，加上分隔壁的厚度的两倍。当满足这些条件时，可以通过具有降低的摩擦特性的本发明的导管和阀门可滑动地插入和移除较大直径的内导管。此外，在阀分隔件和端盖之间设置有压缩环，其使阀分隔件朝向端盖向外朝向其孔径向外弯曲。这又改善了密封特性。此外，公开了一种用于隔板的改进的狭缝设计。

9. 发明授权

US07850714B2 Segmented tissue-to-tissue anchoring device and method of using the same 有权
标题翻译：分段组织到组织锚定装置及其使用方法
公开(公告)号：US07850714B2
公开(公告)日：2010-12-14
申请号：US11640449
申请日：2006-12-15
申请人： John A. Rotella , Donald J. McMichael , Luis A. Davila , Alphonse DeMarco
发明人： John A. Rotella , Donald J. McMichael , Luis A. Davila , Alphonse DeMarco
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0487 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/06052
摘要： The invention describes an apparatus and method of use for anchoring two or more body tissue layers to one another. The apparatus includes a plurality of individual anchor segments that are placeable within a body cavity. The segments may assume a first relaxed state wherein the segments are movable relative to each other and alignable along an initial longitudinal axis for initial placement of the apparatus through the body tissue layers. Once placed within the body cavity, the anchor segments are manipulated into a second rigid state with an actuator wherein the segments assume a rigid configuration at a transverse angle relative to the initial longitudinal axis.
摘要翻译：本发明描述了一种用于将两个或多个身体组织层彼此锚定的装置和方法。该装置包括可放置在体腔内的多个单个锚段。所述段可以呈现第一松弛状态，其中所述段可相对于彼此移动并且沿着初始纵向轴线对准，用于初始设置穿过身体组织层的位置。一旦放置在体腔内，锚定段被操纵成具有致动器的第二刚性状态，其中段相对于初始纵向轴以横向角呈现刚性构型。

10. 发明授权

US5466230A Catheter sheath introducer with strain relief 失效
标题翻译：导管鞘引导器与应变消除
公开(公告)号：US5466230A
公开(公告)日：1995-11-14
申请号：US261087
申请日：1994-06-09
申请人： Luis A. Davila
发明人： Luis A. Davila
IPC分类号： A61M25/00 , A61M25/06 , A61M5/00
CPC分类号： A61M25/0662 , A61M2025/0098 , A61M25/0054
摘要： A catheter sheath introducer comprising a tubular sheath having a proximal end and a distal end are provided. A hub is coupled to the proximal end of the tubular sheath and a coil spring is also provided. The coil spring is positioned about the proximal end of the tubular sheath, and the sheath and coil spring are coupled to the hub in such a way that the tubular sheath and coil spring extend within the hub and out from the hub whereby the strain produced when the tubular sheath and hub are moved relative to one another is relieved.
摘要翻译：提供了包括具有近端和远端的管状护套的导管护套引导器。轮毂联接到管状护套的近端并且还提供螺旋弹簧。螺旋弹簧围绕管状护套的近端定位，并且鞘和螺旋弹簧以这样的方式联接到轮毂，使得管状护套和螺旋弹簧在轮毂内延伸并从轮毂离开，由此产生的应变管状护套和轮毂彼此相对移动。

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