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1. 发明申请

US20060135984A1 Devices for maintaining patency of surgically created channels in tissue 有权
公开(公告)号：US20060135984A1
公开(公告)日：2006-06-22
申请号：US11335263
申请日：2006-01-18
申请人： Thomas Kramer , Bryan Loomas , Christopher Willink , Thomas Keast , Edmund Roschak
发明人： Thomas Kramer , Bryan Loomas , Christopher Willink , Thomas Keast , Edmund Roschak
IPC分类号： A61M29/00
CPC分类号： A61M29/02 , A61B17/3478 , A61B2017/00252 , A61B2017/22042 , A61B2017/22044 , A61B2017/3488 , A61B2018/00541 , A61B2090/036 , A61B2090/395
摘要： Devices and methods for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having chronic obstructive pulmonary disease. The methods and devices create channels in lung tissue and maintain the patency of these surgically created channels in tissue. Maintaining the patency of the channels allows air to pass directly out of the lung tissue which facilitates the exchange of oxygen ultimately into the blood and/or decompresses hyper-inflated lungs.

2. 发明申请

US20060116749A1 Devices for maintaining patency of surgically created channels in tissue 有权
标题翻译：用于维持组织中外科手术通道的通畅的装置
公开(公告)号：US20060116749A1
公开(公告)日：2006-06-01
申请号：US11335040
申请日：2006-01-18
申请人： Christopher Willink , Thomas Kramer , Bryan Loomas , Edmund Roschak
发明人： Christopher Willink , Thomas Kramer , Bryan Loomas , Edmund Roschak
IPC分类号： A61M31/00
CPC分类号： A61M25/10 , A61B17/3478 , A61B2017/00252 , A61B2017/00809 , A61F2/2412 , A61F2/91 , A61F2/958 , A61F2002/043 , A61M25/0084 , A61M25/1002
摘要： Devices and methods for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having chronic obstructive pulmonary disease. The methods and devices create channels in lung tissue and maintain the patency of these surgically created channels in tissue. Maintaining the patency of the channels allows air to pass directly out of the lung tissue which facilitates the exchange of oxygen ultimately into the blood and/or decompresses hyper-inflated lungs.
摘要翻译：用于改变肺内气流的装置和方法，以改善个体，特别是患有慢性阻塞性肺疾病的个体的呼气循环。方法和装置在肺组织中产生通道并保持这些外科手术通道在组织中的通畅。保持通道的通畅使空气能够直接从肺组织中通过，这有助于氧气最终进入血液和/或减压超膨胀的肺。

3. 发明申请

US20060276807A1 Methods for treating chronic obstructive pulmonary disease 审中-公开
标题翻译：治疗慢性阻塞性肺疾病的方法
公开(公告)号：US20060276807A1
公开(公告)日：2006-12-07
申请号：US11357639
申请日：2006-02-16
申请人： Thomas Keast , Julia Rasor , Bryan Loomas , Dave Haugaard , Edmund Roschak
发明人： Thomas Keast , Julia Rasor , Bryan Loomas , Dave Haugaard , Edmund Roschak
IPC分类号： A61B17/10 , A61B5/05 , A61B5/08
CPC分类号： A61B17/064 , A61B5/489 , A61B8/06 , A61B8/12 , A61B8/445 , A61B17/0644 , A61B17/08 , A61B17/11 , A61B17/22 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/1815 , A61B90/36 , A61B2017/00106 , A61B2017/00252 , A61B2017/00575 , A61B2017/00809 , A61B2017/1135 , A61B2017/1139 , A61B2017/22067 , A61B2017/22077 , A61B2017/3425 , A61B2017/3484 , A61B2018/00005 , A61B2018/00029 , A61B2018/00214 , A61B2018/00273 , A61B2018/00285 , A61B2018/00541 , A61B2018/1425 , A61B2018/1437 , A61B2018/1475 , A61B2018/1497 , A61B2090/08021 , A61B2090/3782 , A61B2090/395 , A61F2/02 , A61F2/07 , A61F2/20 , A61F2/2412 , A61F2/2418 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/92 , A61F2002/043 , A61F2002/8483 , A61F2220/005 , A61F2220/0066 , A61F2220/0075 , A61F2230/0058 , A61F2230/0076 , A61F2230/0078 , A61F2230/0091 , A61N2007/0078
摘要： The methods and devices disclosed altering gaseous flow within a lung to improve the expiration cycle of individuals having Chronic Obstructive Pulmonary Disease.
摘要翻译：所公开的方法和装置改变肺内的气流以改善具有慢性阻塞性肺疾病的个体的呼气循环。

4. 发明授权

US6159182A Reusable cannula with disposable seal 失效
标题翻译：具有一次性密封的可重复使用的套管
公开(公告)号：US6159182A
公开(公告)日：2000-12-12
申请号：US83772
申请日：1998-05-22
申请人： John Davis , Tim J. Kovac , Thomas Kramer , Bryan Loomas , John To
发明人： John Davis , Tim J. Kovac , Thomas Kramer , Bryan Loomas , John To
IPC分类号： A61B1/00 , A61B17/00 , A61B17/34 , A61M39/02 , A61M5/178
CPC分类号： A61B17/3462 , A61B17/3498 , A61B17/3417 , A61B17/3474 , A61B2017/0023 , A61B2017/349
摘要： A disposable seal assembly for use with a reusable cannula, where the seal assembly is designed for use with the cannula during a single medical procedure and the cannula is designed for multiple uses (each time with a different seal assembly) during a number of medical procedures. The seal assembly includes both a flapper valve fluid seal (for sealing the cannula when no medical instrument is inserted through the seal assembly) and at least one instrument seal (for sealing the cannula when a medical instrument is inserted through the seal assembly). Preferably, the seal assembly has a body with a flange which can be snapped onto the cannula before use, and readily removed after use. Also preferably, the flapper valve has an over-centered hinge. In other embodiments, the invention is a seal assembly which includes at least one double instrument seal including a sacrificial flange and a sealing flange, and optionally also a flapper valve. The sealing flange seals the cannula when a medical instrument is inserted through the seal assembly even when the sacrificial flange has been cut during insertion of the instrument. In other embodiments, the invention is a system including a reusable cannula, and a disposable seal assembly of any of the described types which can be snapped onto the cannula before use and readily removed after use.
摘要翻译：一种与可重复使用的插管一起使用的一次性密封组件，其中密封组件设计成在单个医疗过程期间与套管一起使用，并且套管被设计为在多个医疗程序期间的多次使用（每次具有不同的密封组件）。密封组件包括挡板阀流体密封件（当没有医疗器械通过密封组件插入时用于密封插管）和至少一个仪器密封件（当医疗器械通过密封组件插入时用于密封套管）。优选地，密封组件具有带法兰的主体，该凸缘可以在使用之前被卡扣在套管上，并且在使用后容易地移除。还优选地，挡板阀具有过中心的铰链。在其他实施例中，本发明是一种密封组件，其包括至少一个双重仪器密封件，其包括牺牲凸缘和密封凸缘，以及可选地还有挡板阀。当医疗器械插入密封组件时，密封法兰密封套管，即使在插入仪器期间牺牲法兰被切割时。在其他实施例中，本发明是一种包括可重复使用的套管和任何所述类型的一次性密封组件的系统，其可以在使用之前被卡扣到套管上并且在使用后容易地移除。

5. 发明授权

US5820606A Reusable cannula with disposable seal 失效
公开(公告)号：US5820606A
公开(公告)日：1998-10-13
申请号：US661760
申请日：1996-06-11
申请人： John Davis , Tim J. Kovac , Thomas Kramer , Bryan Loomas , John To
发明人： John Davis , Tim J. Kovac , Thomas Kramer , Bryan Loomas , John To
IPC分类号： A61B1/00 , A61B17/00 , A61B17/34 , A61M39/02 , A61M5/00
CPC分类号： A61B17/3462 , A61B17/3498 , A61B17/3417 , A61B17/3474 , A61B2017/0023 , A61B2017/349
摘要： A disposable seal assembly for use with a reusable cannula, where the seal assembly is designed for use with the cannula during a single medical procedure and the cannula is designed for multiple uses (each time with a different seal assembly) during a number of medical procedures. The seal assembly includes both a flapper valve fluid seal (for sealing the cannula when no medical instrument is inserted through the seal assembly) and at least one instrument seal (for sealing the cannula when a medical instrument is inserted through the seal assembly). Preferably, the seal assembly has a body with a flange which can be snapped onto the cannula before use, and readily removed after use. Also preferably, the flapper valve has an over-centered hinge. In other embodiments, the invention is a seal assembly which includes at least one double instrument seal including a sacrificial flange and a sealing flange, and optionally also a flapper valve. The sealing flange seals the cannula when a medical instrument is inserted through the seal assembly even when the sacrificial flange has been cut during insertion of the instrument. In other embodiments, the invention is a system including a reusable cannula, and a disposable seal assembly of any of the described types which can be snapped onto the cannula before use and readily removed after use.

6. 发明授权

US08985116B2 Layered nasal devices 有权
标题翻译：分层鼻装置
公开(公告)号：US08985116B2
公开(公告)日：2015-03-24
申请号：US11759916
申请日：2007-06-07
申请人： Rajiv Doshi , Bryan Loomas , Ryan Kendall Pierce , Arthur Ferdinand , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack , Daniel Francis Kennedy
发明人： Rajiv Doshi , Bryan Loomas , Ryan Kendall Pierce , Arthur Ferdinand , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack , Daniel Francis Kennedy
IPC分类号： A61M11/00 , A61M16/06 , A62B23/06 , A61M16/08 , A61M16/20 , A61M16/10 , A61F5/08 , A61M15/08 , A61F5/56
CPC分类号： A62B23/06 , A61F5/08 , A61F5/56 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0688 , A61M16/0866 , A61M16/106 , A61M16/208
摘要： Described herein are nasal devices. In particular, layered nasal respiratory devices are described. Layered nasal device may include a layered airflow resistor that is configured to resist airflow in a first direction more than airflow in a second direction and that includes a flap valve adjacent to a flap valve limiting layer and an adhesive holdfast layer that is configured to secure the layered airflow resistor in communication with the subject's nasal cavity. Methods of using and methods of assembling layered nasal device are also described.
摘要翻译：这里描述的是鼻装置。特别地，描述了分层的鼻呼吸装置。层状鼻装置可以包括分层气流阻力器，其被配置成抵抗第一方向上的气流，而不是沿着第二方向的气流，并且包括与瓣阀限制层相邻的瓣阀和被配置成固定分层气流电阻器与受试者的鼻腔连通。还描述了使用方法和组装分层鼻装置的方法。

7. 发明授权

US08944071B2 Method for treating an asthma attack 有权
标题翻译：治疗哮喘发作的方法
公开(公告)号：US08944071B2
公开(公告)日：2015-02-03
申请号：US13590129
申请日：2012-08-20
申请人： Bryan Loomas , Michael D. Laufer , David P. Thompson
发明人： Bryan Loomas , Michael D. Laufer , David P. Thompson
IPC分类号： A61B19/00 , A61F7/12 , A61B18/18 , A61M29/00 , A61B18/08 , A61B18/02 , A61B18/14 , A61M29/02 , A61N1/40 , A61N5/00 , A61N1/06 , A61B18/00 , A61M25/00 , A61B17/00
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung are disclosed. The damaging of lung cells, damaging tissue, causing trauma, and/or destroying smooth muscle tone with the apparatus may be accomplished via any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.
摘要翻译：公开了通过用插入肺内气道的装置来增加由肺损伤肺细胞，损伤组织，引起创伤和/或破坏气道平滑肌张力的气体交换的方法。可以通过以下任何一种或组合来实现肺细胞损伤，损伤组织，引起创伤和/或破坏平滑肌张力：加热气道; 冷气道向气道输送液体; 向气道输送气体; 刺穿气道; 撕裂气道; 切断气道; 将超声波应用于气道; 并向气道施加电离辐射。

8. 发明授权

US08020700B2 Packaging and dispensing nasal devices 有权
标题翻译：包装和分配鼻装置
公开(公告)号：US08020700B2
公开(公告)日：2011-09-20
申请号：US12329271
申请日：2008-12-05
申请人： Rajiv Doshi , Bryan Loomas , Enrique F. Mendez , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack
发明人： Rajiv Doshi , Bryan Loomas , Enrique F. Mendez , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack
IPC分类号： B65D83/10 , A61M15/08
CPC分类号： B26D3/10 , B26D3/08 , B26F1/02 , B26F1/3846
摘要： Described herein are packaging systems for nasal devices, and methods of packaging and/or dispensing nasal devices. A packaging system may include one or a plurality of nasal devices removably secured to a support backing, and a dispenser. In some variations an applicator may also be included. Methods of using and methods of assembling packaging systems and dispensers are also described.
摘要翻译：这里描述了用于鼻装置的包装系统，以及包装和/或分配鼻装置的方法。包装系统可以包括可拆卸地固定到支撑背衬的一个或多个鼻部装置和分配器。在一些变型中，还可以包括施用器。还描述了使用方法和组装包装系统和分配器的方法。

9. 发明申请

US20100204689A1 METHOD FOR TREATING AN ASTHMA ATTACK 有权
标题翻译：治疗哮喘病的方法
公开(公告)号：US20100204689A1
公开(公告)日：2010-08-12
申请号：US12765704
申请日：2010-04-22
申请人： Christopher J. Danek , Bryan Loomas , Thomas Keast , Michael D. Laufer
发明人： Christopher J. Danek , Bryan Loomas , Thomas Keast , Michael D. Laufer
IPC分类号： A61B17/00 , A61B18/04
CPC分类号： A61N5/00 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2090/3614 , A61M25/0043 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要翻译：在可逆性慢性阻塞性肺疾病如哮喘发作的急性发作期间治疗肺的方法。该方法包括将能量传递到气道的气道壁，使得气道的直径增加。在哮喘发作之前，期间或之后，能量可能转移到气道壁。能量可以以足以临时或永久地增加气道直径的量来转移。该方法可以在气道打开，关闭或部分关闭时进行。

10. 发明授权

US07422584B2 Extrapleural airway device and method 有权
标题翻译：胸外气道装置及方法
公开(公告)号：US07422584B2
公开(公告)日：2008-09-09
申请号：US10615491
申请日：2003-07-07
申请人： Bryan Loomas , Gary Kaplan
发明人： Bryan Loomas , Gary Kaplan
IPC分类号： A61B18/18
CPC分类号： A61F2/04 , A61F2002/046
摘要： This is directed to improving the gaseous exchange in a lung of an individual and particularly, this is directed to improving the gaseous exchange in individuals having chronic obstructive pulmonary disease. It generally includes fluidly connecting the lung to an extrapleural airway such as the trachea. In one variation, a conduit is deployed to place the lung and the trachea in fluid communication which allows trapped oxygen-reduced air to pass directly out of the lung and into the trachea. Removing nonfunctional air from the lung tends to improve the gaseous exchange of oxygen into the blood and decompress hyper-inflated lungs. Sealant and biocompatible adhesives may be provided on the exterior of the conduit to prevent side flow, leaks and to otherwise prevent air from entering spaces not intended to receive air such as the pleura space.
摘要翻译：这旨在改善个体肺中的气体交换，特别是涉及改善具有慢性阻塞性肺疾病的个体中的气体交换。它通常包括将肺流体连接到胸膜前气道如气管。在一个变型中，部署导管以将肺和气管置于流体连通中，其允许被捕获的减氧空气直接通过肺部并进入气管。从肺部去除非功能性空气有助于改善氧气进入血液的气体交换并减压超膨胀的肺。可以在导管的外部设置密封剂和生物相容性粘合剂，以防止侧流，泄漏并防止空气进入不想接收诸如胸膜空间的空气的空间。

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