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1. 发明申请

US20110026009A1 Surface Mapping by Optical Manipulation of Particles in Relation to a Functionalized Surface 有权
标题翻译：通过光学操作颗粒与功能化表面的表面贴图
公开(公告)号：US20110026009A1
公开(公告)日：2011-02-03
申请号：US12440949
申请日：2007-09-14
申请人： Christopher Knutson , Crystal Duke , Gary Stacey , Dan Mueth , Evan Tanner , Osman Akcakir , Haojun Fu , Robert Lancelot , Tania Chakrabarty , Kenneth Bradley
发明人： Christopher Knutson , Crystal Duke , Gary Stacey , Dan Mueth , Evan Tanner , Osman Akcakir , Haojun Fu , Robert Lancelot , Tania Chakrabarty , Kenneth Bradley
IPC分类号： G01N33/48 , G01B11/30
CPC分类号： G01N33/48 , G01N33/54373 , G01N33/80
摘要： Methods and apparatus for analyzing surface properties of particles are provided. A method for analyzing the surface properties of the particle includes a associating a first particle with a first capture zone having a specific binding affinity for a first chemical species, applying an optical force to the first particle, sensing a response of the first particle to the optical force, and using the sensed response to determine the presence, absence or quantity of the first chemical species on the first particle surface. This process may be repeated in parallel to test multiple particles. In addition to directly testing the surface properties of the particles, the method can be used in direct, indirect and competitive assays to determine the presence, absence or quantity of free or immobilized analytes. A fluidic cartridge with capture zones having avidities that are tuned for the use of optical forces is provided. A software routine for performing the method is also provided.
摘要翻译：提供了分析颗粒表面性质的方法和装置。用于分析颗粒的表面性质的方法包括将第一颗粒与对第一化学物质具有特异性结合亲和力的第一捕获区缔合，向第一颗粒施加光学力，感测第一颗粒对第一颗粒的响应并且使用感测到的响应来确定第一颗粒表面上的第一化学物质的存在，不存在或数量。该过程可以并行重复以测试多个颗粒。除了直接测试颗粒的表面性质之外，该方法可用于直接，间接和竞争性测定，以确定游离或固定化分析物的存在，不存在或数量。提供了一种具有捕获区域的流体盒，其具有被调整以用于光学力的空间。还提供了用于执行该方法的软件程序。

2. 发明授权

US08169600B2 Surface mapping by optical manipulation of particles in relation to a functionalized surface 有权
标题翻译：通过相对于功能化表面的颗粒的光学操作的表面映射
公开(公告)号：US08169600B2
公开(公告)日：2012-05-01
申请号：US12440949
申请日：2007-09-14
申请人： Christopher Knutson , Crystal Duke , Gary Stacey , Dan Mueth , Evan Tanner , Osman Akcakir , Haojun Fu , Robert Lancelot , Tania Chakrabarty , Kenneth Bradley
发明人： Christopher Knutson , Crystal Duke , Gary Stacey , Dan Mueth , Evan Tanner , Osman Akcakir , Haojun Fu , Robert Lancelot , Tania Chakrabarty , Kenneth Bradley
IPC分类号： G01N33/48
CPC分类号： G01N33/48 , G01N33/54373 , G01N33/80
摘要： Methods and apparatus for analyzing surface properties of particles are provided. A method for analyzing the surface properties of the particle includes a associating a first particle with a first capture zone having a specific binding affinity for a first chemical species, applying an optical force to the first particle, sensing a response of the first particle to the optical force, and using the sensed response to determine the presence, absence or quantity of the first chemical species on the first particle surface. This process may be repeated in parallel to test multiple particles. In addition to directly testing the surface properties of the particles, the method can be used in direct, indirect and competitive assays to determine the presence, absence or quantity of free or immobilized analytes. A fluidic cartridge with capture zones having avidities that are tuned for the use of optical forces is provided. A software routine for performing the method is also provided.
摘要翻译：提供了分析颗粒表面性质的方法和装置。用于分析颗粒的表面性质的方法包括将第一颗粒与对第一化学物质具有特异性结合亲和力的第一捕获区缔合，向第一颗粒施加光学力，感测第一颗粒对第一颗粒的响应并且使用感测到的响应来确定第一颗粒表面上的第一化学物质的存在，不存在或数量。该过程可以并行重复以测试多个颗粒。除了直接测试颗粒的表面性质之外，该方法可用于直接，间接和竞争性测定，以确定游离或固定化分析物的存在，不存在或数量。提供了一种具有捕获区域的流体盒，其具有被调整以用于光学力的空间。还提供了用于执行该方法的软件程序。

3. 发明授权

US08758321B2 System and method for active cooling of stored blood products 失效
标题翻译：储存血液制品主动冷却的系统和方法
公开(公告)号：US08758321B2
公开(公告)日：2014-06-24
申请号：US12779444
申请日：2010-05-13
申请人： Gary Stacey , Robert E. Putt , Michael R. D'Arrigo , Robert Lancelot , Timothy Olaska , Steven Portela , Frank Jason Black
发明人： Gary Stacey , Robert E. Putt , Michael R. D'Arrigo , Robert Lancelot , Timothy Olaska , Steven Portela , Frank Jason Black
IPC分类号： A61B19/00 , F25D3/08
CPC分类号： F25D15/00 , F25D17/06 , F25D2317/067 , F25D2331/804
摘要： A portable blood storage device includes an outer housing an inner housing. The outer housing defines the structure of the blood storage device. The inner housing is located within the outer housing and has an interior cavity for storing collected blood and/or blood components. The inner housing has an open top to allow access to the interior cavity. The storage device also has an inlet duct and a return duct located within the interior cavity. The inlet duct is fluidly connectable to a cooling device and brings conditioned air into the storage device when fluidly connected to the cooling device. The return duct is also fluidly connectable to the cooling device and returns exhaust air to the cooling device when fluidly connected.
摘要翻译：便携式血液存储装置包括外壳体和内壳体。外壳限定血液储存装置的结构。内壳体位于外壳体内并且具有用于存储收集的血液和/或血液成分的内部空腔。内部壳体具有敞开的顶部以允许进入内部空腔。存储装置还具有位于内部空腔内的入口管道和返回管道。入口管道可流体地连接到冷却装置，并且当流体地连接到冷却装置时将经调节的空气带入存储装置。返回管道也可流体地连接到冷却装置，并在流体连接时将排气返回到冷却装置。

4. 发明申请

US20110082437A1 System and Method For Active Cooling of Stored Blood Products 失效
标题翻译：储存血液制品主动冷却的系统和方法
公开(公告)号：US20110082437A1
公开(公告)日：2011-04-07
申请号：US12779444
申请日：2010-05-13
申请人： Gary Stacey , Robert E. Putt , Michael R. D'Arrigo , Robert Lancelot , Timothy Olaska , Steven Portela , Frank Jason Black
发明人： Gary Stacey , Robert E. Putt , Michael R. D'Arrigo , Robert Lancelot , Timothy Olaska , Steven Portela , Frank Jason Black
IPC分类号： A61J1/14 , F25D31/00 , F25D17/04 , A61J1/18
CPC分类号： F25D15/00 , F25D17/06 , F25D2317/067 , F25D2331/804
摘要： A portable blood storage device includes an outer housing an inner housing. The outer housing defines the structure of the blood storage device. The inner housing is located within the outer housing and has an interior cavity for storing collected blood and/or blood components. The inner housing has an open top to allow access to the interior cavity. The storage device also has an inlet duct and a return duct located within the interior cavity. The inlet duct is fluidly connectable to a cooling device and brings conditioned air into the storage device when fluidly connected to the cooling device. The return duct is also fluidly connectable to the cooling device and returns exhaust air to the cooling device when fluidly connected.
摘要翻译：便携式血液存储装置包括外壳体和内壳体。外壳限定血液储存装置的结构。内壳体位于外壳体内并且具有用于存储收集的血液和/或血液成分的内部空腔。内部壳体具有敞开的顶部以允许进入内部空腔。存储装置还具有位于内部空腔内的入口管道和返回管道。入口管道可流体地连接到冷却装置，并且当流体地连接到冷却装置时将经调节的空气带入存储装置。返回管道也可流体地连接到冷却装置，并在流体连接时将排气返回到冷却装置。

5. 发明申请

US20130060214A1 NEGATIVE DRAWSTRING SEAL FOR AN OSTOMY BAG 有权
标题翻译：负片包装袋
公开(公告)号：US20130060214A1
公开(公告)日：2013-03-07
申请号：US13697014
申请日：2011-05-10
申请人： Alastair Willoughby , Mark Rogers , Gary Stacey , Wai Chan
发明人： Alastair Willoughby , Mark Rogers , Gary Stacey , Wai Chan
IPC分类号： A61F5/445
CPC分类号： A61F5/445 , A61F5/448
摘要： An ostomy body side member with a sealing member is provided. The sealing member has a fixed base member defining an opening having a first diameter and a resilient sealing element comprising a stoma receiving orifice defining an inner boundary. The inner boundary of the stoma receiving orifice has a second diameter that is smaller than the first diameter of the frame. The sealing member is also provided with at least one adjustment member coupled between the fixed base member and the resilient sealing element. Furthermore, an alignment member for adjusting the tension of the at least one adjustment member is provided thereby allowing the diametrical dimension of the stoma sealing orifice to be adjusted from a first diameter to a second diameter.
摘要翻译：提供具有密封构件的造口体侧构件。密封构件具有限定具有第一直径的开口的固定基部构件和包括限定内部边界的造口接收孔的弹性密封元件。造口接收孔的内边界具有小于框架的第一直径的第二直径。密封构件还设置有联接在固定基部构件和弹性密封元件之间的至少一个调节构件。此外，提供了用于调节至少一个调节构件的张力的对准构件，从而允许气孔密封孔的直径尺寸从第一直径调节到第二直径。

6. 发明申请

US20120179124A1 CONTROLLED DISCHARGE OSTOMY APPLIANCE AND SHIELD THEREFOR 有权
标题翻译：控制放电器具及其屏蔽
公开(公告)号：US20120179124A1
公开(公告)日：2012-07-12
申请号：US13395047
申请日：2010-09-09
申请人： Tinh Nguyen-Demary , John Cline , John Blum , Gary Stacey , Philip Davies , Trevor Beckett
发明人： Tinh Nguyen-Demary , John Cline , John Blum , Gary Stacey , Philip Davies , Trevor Beckett
IPC分类号： A61F5/441 , A61F5/445
CPC分类号： A61F5/445 , A61F5/441 , A61F5/448 , A61F2005/4486
摘要： A controlled discharge ostomy appliance assembly comprises (i) a stoma seal that is self-urging with a dynamic damping characteristic that resists changes of seal volume, (ii) a press-fit coupling member displaceable from an unlocked position to a locked position as part of a press-fit process, and (iii) a single-use frangible portion. The assembly further includes a protector shield removably fastened to the appliance forming a combined assembly therewith. The protector shield comprises (i) a seal displacer manipulable for displacing the stoma seal to a non-operative position ready for fitting, (ii) a substantially rigid coupling member guard portion for protecting the state of the coupling member, and (iii) a bracing portion for bracing the single-use frangible portion.
摘要翻译：受控放电造口术器具组件包括（i）具有阻止密封体积变化的动态阻尼特性的自推动的造口密封，（ii）可从解锁位置移位到锁定位置的压配合联构件作为部分的压配合过程，以及（iii）单次使用的易碎部分。组件还包括可拆卸地紧固到器具的保护器屏蔽件，其形成与之组合的组件。保护罩包括（i）可操纵的密封置换器，用于将造口密封件移位到准备好装配的非操作位置，（ii）用于保护联接构件的状态的基本上刚性的联接构件保护部分，以及（iii）用于支撑单次使用的易碎部分的支撑部分。

7. 发明申请

US20120110696A1 LysM Receptor-Like Kinases To Improve Plant Defense Response Against Fungal Pathogens 有权
标题翻译： LysM受体样激酶，以提高植物对真菌病原体的防御反应
公开(公告)号：US20120110696A1
公开(公告)日：2012-05-03
申请号：US13347199
申请日：2012-01-10
申请人： Jinrong Wan , Gary Stacey , Minviluz Stacey , Xuecheng Zhang
发明人： Jinrong Wan , Gary Stacey , Minviluz Stacey , Xuecheng Zhang
IPC分类号： A01H5/00 , A01H1/06
CPC分类号： C12N15/8282 , C12N9/12
摘要： Perception of chitin fragments (chitooligosaccharides) is an important first step in plant defense response against fungal pathogen. LysM receptor-like kinases (LysM RLKs) are instrumental in this perception process. LysM RLKs also play a role in activating transcription of chitin-responsive genes (CRGs) in plants. Mutations in the LysM kinase receptor genes or the downstream CRGs may affect the fungal susceptibility of a plant. Mutations in LysM RLKs or transgenes carrying the same may be beneficial in imparting resistance against fungal pathogens.
摘要翻译：几丁质片段（壳寡糖）的感知是植物对真菌病原体防御反应的重要第一步。 LysM受体样激酶（LysM RLKs）在此感知过程中起了重要作用。 LysM RLKs也在植物中激活壳多糖应答基因（CRG）的转录中发挥作用。 LysM激酶受体基因或下游CRG中的突变可能影响植物的真菌易感性。 LysM RLK中的突变或携带其的转基因可能有益于赋予对真菌病原体的抗性。

8. 发明授权

US07348203B2 Hermetic packaging 有权
标题翻译：密封包装
公开(公告)号：US07348203B2
公开(公告)日：2008-03-25
申请号：US10523528
申请日：2003-09-01
申请人： Tej Paul Kaushal , Paul Antony Manning , John Peter Gillham , Gary Stacey , David Martin Pooley , Peter Georg Laitenberger
发明人： Tej Paul Kaushal , Paul Antony Manning , John Peter Gillham , Gary Stacey , David Martin Pooley , Peter Georg Laitenberger
IPC分类号： H01L21/00 , H01L31/0203 , H01J5/02 , G02B6/36
CPC分类号： B81B7/0041 , G01J5/02 , G01J5/0285 , G01J5/04 , G01J5/045 , G01J5/08 , G01J5/0806 , G02B6/4201 , G02B6/4204 , G02B6/4251 , H01L21/50 , H01L23/10 , H01L2224/48091 , H01L2924/01322 , H01L2924/00014 , H01L2924/00
摘要： A method of hermetically packaging an electronic device (8), in an enclosure (2) comprising mutually inter-engageable first and second housing members (4, 6), comprising the steps of securing the electronic device (8) to the first housing member (4), engaging the first (4) and second (6) housing members such that an hermetic seal is provided there between, wherein the engagement step is performed in a controlled atmosphere. The hermetic seal may be provided by an interference fit between the first (4) and second (6) housing members or via sealing means (16) interposed between the housing members (4, 6). The second housing member (6) may comprise an optical element (20), for example a window or lens. The packaging method is particularly applicable to packaging thermal detectors, for example microbolometer arrays.
摘要翻译：一种在包括相互可互相接合的第一和第二壳体构件（4,6）的外壳（2）中气密地包装电子设备（8）的方法，包括以下步骤：将所述电子设备（8）固定到所述第一壳体构件（4），接合所述第一（4）和第二（6）壳体构件，使得在其间设置气密密封，其中所述接合步骤在受控的气氛中进行。气密密封可以通过第一（4）和第二（6）壳体构件之间的过盈配合或者插入在壳体构件（4,6）之间的密封装置（16）来提供。第二壳体构件（6）可以包括光学元件（20），例如窗口或透镜。包装方法特别适用于包装热检测器，例如微电热计阵列。

9. 发明授权

US5769811A Blood-processing machine system 失效
标题翻译：血液加工机系统
公开(公告)号：US5769811A
公开(公告)日：1998-06-23
申请号：US551150
申请日：1995-10-31
申请人： Gary Stacey , Frederick York , David Lamborghini , Steven Liberatore
发明人： Gary Stacey , Frederick York , David Lamborghini , Steven Liberatore
IPC分类号： A61M1/02 , A61M1/30 , A61M1/34 , A61M1/36 , A61M35/00
CPC分类号： A61M1/3693 , A61M1/303 , A61M1/306 , A61M1/308 , A61M1/3696 , A61M1/30 , A61M1/3496 , A61M2205/12 , A61M2205/3306 , A61M2205/50 , A61M2205/6018 , A61M2205/6072
摘要： A multiprotocol blood-processing machine and disposable units for use therewith. The disposable units generally comprise a centrifuge bowl for separating whole blood into blood constituents, an inlet tube for conveying blood into the bowl, an outlet tube for conveying the blood constituents away from the bowl, and a manifold for placing the inlet tube and the outlet tube in fluid communication with a tube from a donor. The manifold has a machine-readable bar-code label for identifying to the blood processing machine which type of disposable unit is being coupled to it. The machine itself comprises a central processing unit that controls overall operation, a first computer memory containing safety-monitoring instructions that cause the central processing unit to monitor various state parameters in order to ensure donor safety, and a second computer memory containing instructions that define at least one apheresis or blood-processing protocol. In some implementations, the second computer memory is removable from and insertable into the blood processing machine by an operator.
摘要翻译：一种多协议血液处理机及其一次性使用单元。一次性单元通常包括用于将全血分离成血液成分的离心机碗，用于将血液输送到碗中的入口管，用于将血液成分输送到碗中的出口管，以及用于将入口管和出口管与来自供体的管流体连通。歧管具有用于识别血液处理机的机器可读条形码标签，该类型的一次性单元正在耦合到该处理机。机器本身包括控制整体操作的中央处理单元，包含安全监视指令的第一计算机存储器，其使中央处理单元监视各种状态参数以确保供体安全;以及第二计算机存储器，其包含在至少一个单采或血液处理协议。在一些实施方式中，第二计算机存储器可由操作者从血液处理机器中移除并插入到血液处理机器中。

10. 发明授权

US09936834B2 Method and apparatus for cartridge-based carbonation of beverages 有权
公开(公告)号：US09936834B2
公开(公告)日：2018-04-10
申请号：US13565214
申请日：2012-08-02
申请人： Thomas J. Novak , Ross Packard , Peter Peterson , Shawn Gulla , Jennifer Caitlin Huot Carlson , Camilla Schmitt , Mark Joseph Cohen , Ross Peter Jones , Nicolas Alejandro Martinez , Miles William Noel Hember , Fabien Yannick Schmitt , Gary Stacey , Niall Allan Mottram , Neil Lester Campbell , Cormac O'Prey , Wai Ting Chan , Nicholas David Rollings , Charles Frazer Kilby , Christopher Paul Richardson , Thomas Bates Jackson , Scott Grubb , Chris Covey , Barry Dobson , Paul Wilkins , Chris Roach , Peter Cauwood , Keith Thompson
发明人： Thomas J. Novak , Ross Packard , Peter Peterson , Shawn Gulla , Jennifer Caitlin Huot Carlson , Camilla Schmitt , Mark Joseph Cohen , Ross Peter Jones , Nicolas Alejandro Martinez , Miles William Noel Hember , Fabien Yannick Schmitt , Gary Stacey , Niall Allan Mottram , Neil Lester Campbell , Cormac O'Prey , Wai Ting Chan , Nicholas David Rollings , Charles Frazer Kilby , Christopher Paul Richardson , Thomas Bates Jackson , Scott Grubb , Chris Covey , Barry Dobson , Paul Wilkins , Chris Roach , Peter Cauwood , Keith Thompson
IPC分类号： B65D85/804 , B65D85/73 , A23L2/54 , B01F15/02 , B01F3/04 , F17C11/00 , A47J31/40 , A47J31/41 , B01F5/10 , B01F5/06
CPC分类号： A47J31/407 , A23L2/54 , A47J31/41 , B01F3/04248 , B01F3/0446 , B01F3/04758 , B01F3/04787 , B01F3/04808 , B01F3/04815 , B01F5/0606 , B01F5/10 , B01F15/0205 , B01F15/0206 , B01F2215/0022 , B65D85/73 , B65D85/8043 , F17C11/00
摘要： Systems, methods and cartridges for carbonating or otherwise dissolving gas in a precursor liquid, such as water, to form a beverage. A gas source can be provided in a cartridge which is used to generate gas that is dissolved into the precursor liquid. A beverage medium, such as a powdered drink mix or liquid syrup, may be provided in the same, or a separate cartridge as the gas source and mixed with the precursor liquid to form a beverage. The use of one or more cartridges for the gas source and/or beverage medium may make for an easy to use and mess-free system for making sparkling beverages, e.g., in the consumer's home.

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