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1. 发明授权

US09167220B2 Synchronized stream packing 有权
公开(公告)号：US09167220B2
公开(公告)日：2015-10-20
申请号：US11918511
申请日：2006-03-16
申请人： Mark Rogers Johnson , Ralf Ostermann , Joseph Sanderson Rice
发明人： Mark Rogers Johnson , Ralf Ostermann , Joseph Sanderson Rice
IPC分类号： H04N5/76 , H04N9/80 , H04N5/92 , H04N9/87 , G11B27/10 , G11B27/30 , H04N21/234 , H04N21/2343 , H04N21/235 , H04N21/236 , H04N21/2365 , H04N21/2368 , H04N21/2381 , H04N21/43 , H04N21/434 , H04N21/435 , H04N21/4363 , H04N21/438 , H04N21/44 , H04N21/4402 , H04N21/488 , H04N21/8547
CPC分类号： H04N9/87 , G11B27/10 , G11B27/105 , G11B27/3027 , G11B2220/2562 , H04N21/23424 , H04N21/234318 , H04N21/235 , H04N21/23614 , H04N21/2365 , H04N21/2368 , H04N21/2381 , H04N21/4307 , H04N21/434 , H04N21/4341 , H04N21/4347 , H04N21/4348 , H04N21/435 , H04N21/4363 , H04N21/4381 , H04N21/44016 , H04N21/440209 , H04N21/4884 , H04N21/8547
摘要： There are provided methods and apparatus for synchronized stream packing of packets that differ contextually between A/V streams in a parallel presentation. A method includes the step of identifying sub-picture/subtitle packets and/or audio packets having arrival timestamps and/or presentation timestamps that match an arrival timestamp and/or a presentation timestamp, respectively, of video packets. The method also includes the step of packing a Video Object Unit (VOBU) and/or a Transport Stream (TS) with the identified sub-picture/subtitle and audio packets and the video packets having the matching timestamps.

2. 发明授权

US09067924B2 1,4 thiazepines/sulfones as BACE1 and/or BACE2 inhibitors 有权
标题翻译： 1,4硫辛啶/砜作为BACE1和/或BACE2抑制剂
公开(公告)号：US09067924B2
公开(公告)日：2015-06-30
申请号：US13405398
申请日：2012-02-27
申请人： Hans Hilpert , Mark Rogers-Evans , Didier Rombach
发明人： Hans Hilpert , Mark Rogers-Evans , Didier Rombach
IPC分类号： A61K31/554 , C07D417/10 , C07D513/04 , C07D417/12
CPC分类号： C07D417/12 , A61K31/554 , C07D513/04
摘要： The present invention relates to 1,4 Thiazepines/Sulfones of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
摘要翻译：本发明涉及具有BACE1和/或BACE2抑制活性的式I的1,4噻嗪类/砜类，其制备方法，含有它们的药物组合物及其作为治疗活性物质的用途。本发明的活性化合物可用于例如治疗和/或预防性治疗。阿尔茨海默病和2型糖尿病。

3. 发明申请

US20140288046A1 NOVEL [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES 有权
标题翻译：新型[1,2,3]三唑[4,5-D]吡啶衍生物
公开(公告)号：US20140288046A1
公开(公告)日：2014-09-25
申请号：US14250781
申请日：2014-04-11
申请人： Jean-Michel Adam , Caterina Bissantz , Uwe Grether , Atsushi Kimbara , Matthias Nettekoven , Stephan Roever , Mark Rogers-Evans
发明人： Jean-Michel Adam , Caterina Bissantz , Uwe Grether , Atsushi Kimbara , Matthias Nettekoven , Stephan Roever , Mark Rogers-Evans
IPC分类号： C07D487/04 , C07D491/107
CPC分类号： C07D487/04 , A61K9/0019 , A61K9/2054 , A61K9/4866 , A61K31/519 , A61K47/10 , C07D491/107
摘要： The invention relates to a compound of formula (I) wherein A, R1 and R2 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
摘要翻译：本发明涉及式（I）化合物，其中A，R 1和R 2如在说明书和权利要求书中所定义。式（I）化合物可以用作药物。

4. 发明授权

US08748418B2 1,4-oxazepines as BACE1 and/or BACE2 inhibitors 失效
标题翻译： 1,4-氧氮杂作为BACE1和/或BACE2抑制剂
公开(公告)号：US08748418B2
公开(公告)日：2014-06-10
申请号：US13415873
申请日：2012-03-09
申请人： Emanuele Gabellieri , Wolfgang Guba , Hans Hilpert , Harald Mauser , Alexander V. Mayweg , Mark Rogers-Evans , Didier Rombach , Andrew Thomas , Thomas Woltering , Wolfgang Wostl
发明人： Emanuele Gabellieri , Wolfgang Guba , Hans Hilpert , Harald Mauser , Alexander V. Mayweg , Mark Rogers-Evans , Didier Rombach , Andrew Thomas , Thomas Woltering , Wolfgang Wostl
IPC分类号： A61K31/553 , C07D413/02 , C07D267/10
CPC分类号： C07D267/10 , C07D413/12
摘要： The present invention relates to 1,4-Oxazepines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
摘要翻译：本发明涉及具有BACE1和/或BACE2抑制活性的式I的1,4-氧氮杂，其制备方法，含有它们的药物组合物及其作为治疗活性物质的用途。本发明的活性化合物可用于例如治疗和/或预防性治疗。阿尔茨海默病和2型糖尿病。

5. 发明申请

US20140006052A1 VENTILATOR BILLING AND INVENTORY MANAGEMENT 审中-公开
标题翻译：通风管理和库存管理
公开(公告)号：US20140006052A1
公开(公告)日：2014-01-02
申请号：US13539024
申请日：2012-06-29
申请人： Tom Steinhauer , Terry Blansfield , Willis Lam , Stephen J. Birch , Mark Rogers
发明人： Tom Steinhauer , Terry Blansfield , Willis Lam , Stephen J. Birch , Mark Rogers
IPC分类号： G06Q50/24 , G06Q10/08
CPC分类号： G06Q30/04 , G06F19/328 , G06F19/3418 , G06F19/3481 , G06Q10/087 , G06Q50/22 , G16H10/60 , G16H40/63
摘要： Accessing ventilator data; and generating a patient billing record based on the ventilator data and/or managing ventilation inventory based on the use of ventilator consumables.
摘要翻译：进入呼吸机数据; 并且基于呼吸机数据生成患者记帐记录和/或基于使用呼吸机消耗品来管理通风盘存。

6. 发明申请

US20130110924A1 WIDE AREA VENTILATION MANAGEMENT 审中-公开
标题翻译：广域通风管理
公开(公告)号：US20130110924A1
公开(公告)日：2013-05-02
申请号：US13287752
申请日：2011-11-02
申请人： Tom Steinhauer , Willis Lam , Mark Rogers , Terry Blansfield , Stephen J. Birch
发明人： Tom Steinhauer , Willis Lam , Mark Rogers , Terry Blansfield , Stephen J. Birch
IPC分类号： G06F15/16
CPC分类号： G06F19/3418
摘要： A method for wide area ventilation management. The method includes wirelessly accessing ventilator data generated by a plurality of networked ventilators, wirelessly transmitting patient information to the plurality of networked ventilators, wherein the patient information facilitates in contextualization of the ventilator data; and wirelessly transmitting protocols and rules to the plurality of networked ventilators.
摘要翻译：一种广域通风管理方法。该方法包括无线地访问由多个联网呼吸机生成的呼吸机数据，将患者信息无线传送到多个联网呼吸机，其中患者信息有利于呼吸机数据的语境化; 以及将协议和规则无线传输到所述多个联网呼吸机。

7. 发明申请

US20130104894A1 AUTOMATIC IMPLEMENTATION OF A VENTILATOR PROTOCOL 审中-公开
标题翻译： “通风机协议”的自动实现
公开(公告)号：US20130104894A1
公开(公告)日：2013-05-02
申请号：US13287935
申请日：2011-11-02
申请人： Tom Steinhauer , Mark Rogers , Terry Blansfield , Stephen J. Birch
发明人： Tom Steinhauer , Mark Rogers , Terry Blansfield , Stephen J. Birch
IPC分类号： A61M16/00
CPC分类号： A61M16/021 , A61M16/0051 , A61M2205/3553 , A61M2205/3584 , A61M2205/3592 , A61M2205/505 , A61M2205/6009 , A61M2205/6018 , A61M2205/6054 , A61M2205/6072 , A61M2205/609
摘要： A method for implementing a ventilator protocol on a ventilator. The method includes accessing the ventilator protocol, and automatically implementing the ventilator protocol on the ventilator via a touch screen display of the ventilator.
摘要翻译：一种在呼吸机上实施呼吸机协议的方法。该方法包括访问呼吸机协议，并通过呼吸机的触摸屏显示器自动实现呼吸机呼吸机协议。

8. 发明申请

US20130104891A1 SUGGESTING VENTILATOR PROTOCOLS 审中-公开
标题翻译：建议通风机协议
公开(公告)号：US20130104891A1
公开(公告)日：2013-05-02
申请号：US13288000
申请日：2011-11-02
申请人： Tom Steinhauer , Timothy Riddle , Thomas George , Mark Rogers , Glen Gee
发明人： Tom Steinhauer , Timothy Riddle , Thomas George , Mark Rogers , Glen Gee
IPC分类号： A61M16/00
CPC分类号： G06F19/3418 , A61M16/0051 , A61M16/021 , A61M2205/3375 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/3592 , A61M2205/505 , A61M2205/52 , A61M2205/60 , A61M2205/6054 , A61M2205/6072 , A61M2205/609 , A61M2205/84 , A61M2209/01 , A61M2230/205 , A61M2230/62 , A61M2230/63 , G16H10/65 , G16H40/40 , G16H50/20 , G16H50/30
摘要： A method for suggesting ventilator protocols includes accessing data from a plurality of ventilators in operation, analyzing an aggregate of the data, and suggesting a protocol for a ventilator of the plurality of ventilators based on the analyzed aggregated data.
摘要翻译：一种用于建议呼吸机协议的方法，包括在操作中访问来自多个呼吸机的数据，基于分析的聚合数据分析数据的总数，以及建议多个呼吸机的呼吸机的协议。

9. 发明申请

US20130060214A1 NEGATIVE DRAWSTRING SEAL FOR AN OSTOMY BAG 有权
标题翻译：负片包装袋
公开(公告)号：US20130060214A1
公开(公告)日：2013-03-07
申请号：US13697014
申请日：2011-05-10
申请人： Alastair Willoughby , Mark Rogers , Gary Stacey , Wai Chan
发明人： Alastair Willoughby , Mark Rogers , Gary Stacey , Wai Chan
IPC分类号： A61F5/445
CPC分类号： A61F5/445 , A61F5/448
摘要： An ostomy body side member with a sealing member is provided. The sealing member has a fixed base member defining an opening having a first diameter and a resilient sealing element comprising a stoma receiving orifice defining an inner boundary. The inner boundary of the stoma receiving orifice has a second diameter that is smaller than the first diameter of the frame. The sealing member is also provided with at least one adjustment member coupled between the fixed base member and the resilient sealing element. Furthermore, an alignment member for adjusting the tension of the at least one adjustment member is provided thereby allowing the diametrical dimension of the stoma sealing orifice to be adjusted from a first diameter to a second diameter.
摘要翻译：提供具有密封构件的造口体侧构件。密封构件具有限定具有第一直径的开口的固定基部构件和包括限定内部边界的造口接收孔的弹性密封元件。造口接收孔的内边界具有小于框架的第一直径的第二直径。密封构件还设置有联接在固定基部构件和弹性密封元件之间的至少一个调节构件。此外，提供了用于调节至少一个调节构件的张力的对准构件，从而允许气孔密封孔的直径尺寸从第一直径调节到第二直径。

10. 发明授权

US08207220B2 Substituted benzothiazoles as orexin antagonists 有权
标题翻译：取代的苯并噻唑作为食欲素拮抗剂
公开(公告)号：US08207220B2
公开(公告)日：2012-06-26
申请号：US12958440
申请日：2010-12-02
申请人： Henner Knust , Matthias Nettekoven , Emmanuel Pinard , Olivier Roche , Mark Rogers-Evans
发明人： Henner Knust , Matthias Nettekoven , Emmanuel Pinard , Olivier Roche , Mark Rogers-Evans
IPC分类号： A61K31/38
CPC分类号： C07D413/12 , C07D403/12 , C07D413/14 , C07D417/12
摘要： The present invention is concerned with novel sulfonamides of formula I wherein R1, R2, Ar, Hetaryl, m and n are as described in the description and claims. The compounds are orexin receptor antagonists, useful in the treatment of disorders, in which orexin pathways are involved.
摘要翻译：本发明涉及式I的新型磺酰胺，其中R 1，R 2，Ar，杂芳基，m和n如说明书和权利要求中所述。这些化合物是食欲素受体拮抗剂，可用于治疗食欲素途径参与的病症。

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