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1. 发明授权

US08747425B2 Percutaneous vein removal device 失效
标题翻译：经皮静脉去除装置
公开(公告)号：US08747425B2
公开(公告)日：2014-06-10
申请号：US13462988
申请日：2012-05-03
申请人： Chris Genau , Edward M. Boyle , Andrew Jones , John F. Harris , Andrew D. Firlik , Navroze S. Mehta
发明人： Chris Genau , Edward M. Boyle , Andrew Jones , John F. Harris , Andrew D. Firlik , Navroze S. Mehta
IPC分类号： A61B17/32
CPC分类号： A61B17/22 , A61B17/00008 , A61B2017/00778 , A61B2017/320044
摘要： A surgical tool for the obliteration of spider veins.
摘要翻译：一种用于消除蜘蛛静脉的手术工具。

2. 发明申请

US20130123819A1 Percutaneous Vein Removal Device 失效
标题翻译：经皮静脉去除装置
公开(公告)号：US20130123819A1
公开(公告)日：2013-05-16
申请号：US13462988
申请日：2012-05-03
申请人： Chris Genau , Edward M. Boyle , Andrew Jones , John F. Harris , Andrew D. Firlik , Navroze S. Mehta
发明人： Chris Genau , Edward M. Boyle , Andrew Jones , John F. Harris , Andrew D. Firlik , Navroze S. Mehta
IPC分类号： A61B17/22
CPC分类号： A61B17/22 , A61B17/00008 , A61B2017/00778 , A61B2017/320044
摘要： A surgical tool for the obliteration of spider veins.
摘要翻译：一种用于消除蜘蛛静脉的手术工具。

3. 发明申请

US20110264124A1 VEIN REMOVAL DEVICE 审中-公开
标题翻译： VEIN拆卸装置
公开(公告)号：US20110264124A1
公开(公告)日：2011-10-27
申请号：US12766165
申请日：2010-04-23
申请人： Edward M. Boyle , Andrew Jones , John F. Harris , Andrew D. Firlik , Navroze Mehta , Chris Genau
发明人： Edward M. Boyle , Andrew Jones , John F. Harris , Andrew D. Firlik , Navroze Mehta , Chris Genau
IPC分类号： A61B17/22
CPC分类号： A61B17/00008
摘要： A surgical tool for the obliteration of spider veins.
摘要翻译：一种用于消除蜘蛛静脉的手术工具。

4. 发明申请

US20130253551A1 PHLEBECTOMY DEVICE AND SYSTEM 审中-公开
标题翻译： PHLEBECTOMY设备和系统
公开(公告)号：US20130253551A1
公开(公告)日：2013-09-26
申请号：US13759377
申请日：2013-02-05
申请人： Edward M. Boyle, M.D. , Andrew Jones, M.D. , John F. Harris , Andrew D. Firlik , Navroze Mehta , Chris Genau
发明人： Edward M. Boyle, M.D. , Andrew Jones, M.D. , John F. Harris , Andrew D. Firlik , Navroze Mehta , Chris Genau
IPC分类号： A61B17/32
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/320016 , A61B17/320758 , A61B2017/00778 , A61B2017/320044
摘要： A surgical tool for the obliteration of spider veins.
摘要翻译：一种用于消除蜘蛛静脉的手术工具。

5. 发明授权

US08050768B2 Methods and apparatus for effectuating a change in a neural-function of a patient 有权
标题翻译：用于实现患者神经功能变化的方法和装置
公开(公告)号：US08050768B2
公开(公告)日：2011-11-01
申请号：US12343427
申请日：2008-12-23
申请人： Andrew D. Firlik , Bradford Evan Gliner , Alan J. Levy , Katrina S. Firlik
发明人： Andrew D. Firlik , Bradford Evan Gliner , Alan J. Levy , Katrina S. Firlik
IPC分类号： A61N1/00
CPC分类号： A61N1/36017 , A61N1/0531 , A61N1/0534 , A61N1/0539 , A61N1/36014 , A61N1/36025 , A61N1/36082 , A61N1/375 , A61N1/3756
摘要： The present disclosure is directed generally to methods and apparatus for effectuating a change in a neural function of a patient. A method in accordance with a particular embodiment includes implanting an electrode at a cortical stimulation site selected to promote recovery of the affected neural-function, with the cortical stimulation site being at least proximate to the cortex. The method can further include estimating a threshold for the specific patient at which an electrical signal delivered via the implanted electrode directly triggers a neural reaction associated with the stimulation site in response to the delivered electrical signal, and electrically stimulating the cortical stimulation site by passing an electrical current through the electrode.
摘要翻译：本公开一般涉及用于实现患者的神经功能变化的方法和装置。根据特定实施例的方法包括将电极植入皮质刺激部位，所述皮质刺激位置被选择以促进受影响的神经功能的恢复，皮层刺激部位至少接近皮层。该方法还可以包括估计特定患者的阈值，在该阈值处，经由植入的电极传送的电信号响应于所输送的电信号而直接触发与刺激部位相关的神经反应，并通过传递电刺激部位电刺激皮质刺激部位电流通过电极。

6. 发明授权

US07945330B2 Systems and methods for automatically optimizing stimulus parameters and electrode configurations for neuro-stimulators 有权
标题翻译：用于自动优化神经刺激器的刺激参数和电极配置的系统和方法
公开(公告)号：US07945330B2
公开(公告)日：2011-05-17
申请号：US12244610
申请日：2008-10-02
申请人： Bradford Evan Gliner , Jeffrey Balzer , Andrew D. Firlik
发明人： Bradford Evan Gliner , Jeffrey Balzer , Andrew D. Firlik
IPC分类号： A61N1/36
CPC分类号： A61N1/36021 , A61N1/0531 , A61N1/0534 , A61N1/0551 , A61N1/0553 , A61N1/36025 , A61N1/36071 , A61N1/36082 , A61N1/36185 , A61N1/375 , A61N1/3756 , G06F19/00
摘要： Methods and devices for automatically optimizing the stimulus parameters and/or the configuration of electrodes to provide neural stimulation to a patient. In one embodiment, a system includes an electrode array having an implantable support member configured to be implanted into a patient and a plurality of therapy electrodes carried by the support member. The system can also have a pulse system operatively coupled to the therapy electrodes to deliver a stimulus to the therapy electrodes, and a sensing device configured to be attached to a sensing location of the patient. The sensing device generates response signals in response to the stimulus. The system can also include a controller operatively, coupled to the pulse system and to the sensing device. The controller includes a computer operable medium that generates command signals that define the stimulus delivered by the pulse system, evaluates the response signals from the sensing device, and determines a desired configuration for the therapy electrodes and/or a desired stimulus to be delivered to the therapy electrodes.
摘要翻译：用于自动优化刺激参数和/或电极配置以向患者提供神经刺激的方法和装置。在一个实施例中，系统包括电极阵列，其具有被配置为植入病人的可植入支撑构件和由支撑构件承载的多个治疗电极。系统还可以具有可操作地耦合到治疗电极的脉冲系统以将刺激传递到治疗电极，以及被配置为附接到患者的感测位置的感测装置。感测装置响应于刺激产生响应信号。该系统还可以包括可操作地耦合到脉冲系统和感测装置的控制器。控制器包括计算机可操作介质，其产生定义由脉冲系统传递的刺激的命令信号，评估来自感测装置的响应信号，并且确定用于治疗电极的期望配置和/或期望的刺激以被传送到治疗电极。

7. 发明申请

US20100131030A1 METHODS AND APPARATUS FOR EFFECTUATING A CHANGE IN A NEURAL-FUNCTION OF A PATIENT 审中-公开
标题翻译：影响患者神经功能改变的方法和装置
公开(公告)号：US20100131030A1
公开(公告)日：2010-05-27
申请号：US12698409
申请日：2010-02-02
申请人： Andrew D. Firlik , Bradford Evan Gliner , Alan J. Levy , Katrina S. Firlik
发明人： Andrew D. Firlik , Bradford Evan Gliner , Alan J. Levy , Katrina S. Firlik
IPC分类号： A61N1/36
CPC分类号： A61N1/36017 , A61N1/0531 , A61N1/0534 , A61N1/0539 , A61N1/36014 , A61N1/36025 , A61N1/36082 , A61N1/375 , A61N1/3756
摘要： The present disclosure is directed generally to methods and apparatus for effectuating a change in a neural function of a patient. A method in accordance with a particular embodiment includes implanting an electrode at a cortical stimulation site selected to promote recovery of the affected neural-function, with the cortical stimulation site being at least proximate to the cortex. The method can further include estimating a threshold for the specific patient at which an electrical signal delivered via the implanted electrode directly triggers a neural reaction associated with the stimulation site in response to the delivered electrical signal, and electrically stimulating the cortical stimulation site by Passing an electrical current through the electrode.
摘要翻译：本公开一般涉及用于实现患者的神经功能变化的方法和装置。根据特定实施例的方法包括将电极植入皮质刺激部位，所述皮质刺激位置被选择以促进受影响的神经功能的恢复，皮层刺激部位至少接近皮层。该方法还可以包括估计特定患者的阈值，在该阈值处，经由植入的电极传送的电信号响应于所输送的电信号直接触发与刺激部位相关联的神经反应，并通过传递电刺激皮质刺激部位电流通过电极。

8. 发明申请

US20090319000A1 METHODS AND APPARATUS FOR EFFECTUATING A CHANGE IN A NEURAL-FUNCTION OF A PATIENT 有权
标题翻译：影响患者神经功能改变的方法和装置
公开(公告)号：US20090319000A1
公开(公告)日：2009-12-24
申请号：US12343427
申请日：2008-12-23
申请人： Andrew D. Firlik , Bradford Evan Gliner , Alan J. Levy , Katrina S. Firlik
发明人： Andrew D. Firlik , Bradford Evan Gliner , Alan J. Levy , Katrina S. Firlik
IPC分类号： A61N1/05
CPC分类号： A61N1/36017 , A61N1/0531 , A61N1/0534 , A61N1/0539 , A61N1/36014 , A61N1/36025 , A61N1/36082 , A61N1/375 , A61N1/3756
摘要： The present disclosure is directed generally to methods and apparatus for effectuating a change in a neural function of a patient. A method in accordance with a particular embodiment includes implanting an electrode at a cortical stimulation site selected to promote recovery of the affected neural-function, with the cortical stimulation site being at least proximate to the cortex. The method can further include estimating a threshold for the specific patient at which an electrical signal delivered via the implanted electrode directly triggers a neural reaction associated with the stimulation site in response to the delivered electrical signal, and electrically stimulating the cortical stimulation site by Passing an electrical current through the electrode.
摘要翻译：本公开一般涉及用于实现患者的神经功能变化的方法和装置。根据特定实施例的方法包括将电极植入皮质刺激部位，所述皮质刺激位置被选择以促进受影响的神经功能的恢复，皮层刺激部位至少接近皮层。该方法还可以包括估计特定患者的阈值，在该阈值处，经由植入的电极传送的电信号响应于所输送的电信号直接触发与刺激部位相关联的神经反应，并通过传递电刺激皮质刺激部位电流通过电极。

9. 发明申请

US20120022611A1 METHODS AND APPARATUS FOR EFFECTUATING A LASTING CHANGE IN A NEURAL-FUNCTION OF A PATIENT 审中-公开
标题翻译：影响患者神经功能变化的方法和装置
公开(公告)号：US20120022611A1
公开(公告)日：2012-01-26
申请号：US13240053
申请日：2011-09-22
申请人： Andrew D. Firlik , Jeffrey Balzer , Bradford Evan Gliner , Alan J. Levy , Carlton B. Morgan , Katrina S. Firlik
发明人： Andrew D. Firlik , Jeffrey Balzer , Bradford Evan Gliner , Alan J. Levy , Carlton B. Morgan , Katrina S. Firlik
IPC分类号： A61N1/36
CPC分类号： A61N1/375 , A61N1/0531 , A61N1/0534 , A61N1/0539 , A61N1/36017 , A61N1/36025 , A61N1/36082 , A61N1/36103 , A61N1/3756
摘要： The following disclosure describes several methods and apparatus for intracranial electrical stimulation to treat or otherwise effectuate a change in neural-functions of a patient. The methods in accordance with the invention can be used to treat brain damage (e.g., stroke, trauma, etc.), brain disease (e.g., Alzheimer's, Pick's, Parkinson's, etc.), and/or brain disorders (e.g., epilepsy, depression, etc.). The methods in accordance with the invention can also be used to enhance neural-function of normal, healthy brains (e.g., learning, memory, etc.), or to control sensory functions (e.g., pain).
摘要翻译：以下公开内容描述了用于治疗或以其他方式实现患者神经功能变化的颅内电刺激的几种方法和装置。根据本发明的方法可用于治疗脑损伤（例如中风，创伤等），脑部疾病（例如阿尔茨海默氏症，皮克病，帕金森氏病等）和/或脑部疾病（例如癫痫，抑郁症等）。根据本发明的方法还可以用于增强正常，健康的大脑（例如学习，记忆等）的神经功能，或用于控制感觉功能（例如疼痛）。

10. 发明授权

US08065012B2 Methods and apparatus for effectuating a lasting change in a neural-function of a patient 有权
标题翻译：用于实现患者神经功能持续变化的方法和装置
公开(公告)号：US08065012B2
公开(公告)日：2011-11-22
申请号：US11834650
申请日：2007-08-06
申请人： Andrew D. Firlik , Jeffrey Balzer , Bradford Evan Gliner , Alan J. Levy , Carlton B. Morgan , Katrina S. Firlik
发明人： Andrew D. Firlik , Jeffrey Balzer , Bradford Evan Gliner , Alan J. Levy , Carlton B. Morgan , Katrina S. Firlik
IPC分类号： A61N1/05
CPC分类号： A61N1/375 , A61N1/0531 , A61N1/0534 , A61N1/0539 , A61N1/36017 , A61N1/36025 , A61N1/36082 , A61N1/36103 , A61N1/3756
摘要： Disclosed are several apparatuses and methods for applying intracranial electrical stimulation to treat or enhance the neural function of the patient. In accordance with the invention, intracranial electrical stimulation can be administered to treat brain damage, brain disease, and/or brain disorders. Additionally the intracranial electrical stimulation can be applied to a normal healthy brain to enhance neural-function or control sensory functions. The electrical stimulation site(s) of the brain are located where neuroplasticity is occurring, expected to occur, or in a region where neuroplasticity is not occurring. The intracranial stimulation is expected to produce a lasting effect on the intended neural activity by applying subthreshold stimulation to the increasing the resting membrane potential of the neurons at the stimulation site.
摘要翻译：公开了几种用于施加颅内电刺激以治疗或增强患者的神经功能的装置和方法。根据本发明，可以施用颅内电刺激来治疗脑损伤，脑疾病和/或脑疾病。此外，颅内电刺激可以应用于正常的健康大脑，以增强神经功能或控制感觉功能。大脑的电刺激部位位于发生神经可塑性，预期发生或未出现神经可塑性的区域。预期颅内刺激通过应用亚阈值刺激来增加刺激部位神经元的静息膜电位，对预期的神经活动产生持久的作用。

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