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1. 发明申请

US20050060033A1 Tissue engineered tendons and ligaments 审中-公开
公开(公告)号：US20050060033A1
公开(公告)日：2005-03-17
申请号：US10913769
申请日：2004-08-06
申请人： Charles Vacanti , Yi Cao , Robert Langer , Joseph Vacanti , Keith Paige , Joseph Upton
发明人： Charles Vacanti , Yi Cao , Robert Langer , Joseph Vacanti , Keith Paige , Joseph Upton
IPC分类号： A61F2/08 , A61L27/18 , A61L27/38 , A61L27/58 , A61F2/02
CPC分类号： A61L27/3804 , A61F2/08 , A61L27/18 , A61L27/3604 , A61L27/3662 , A61L27/3817 , A61L27/3843 , A61L27/386 , A61L27/58 , A61L2430/10 , C08L67/04
摘要： Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.

2. 发明申请

US20070005139A1 Tissue engineered tendons and ligaments 失效
标题翻译：组织工程肌腱和韧带
公开(公告)号：US20070005139A1
公开(公告)日：2007-01-04
申请号：US11351127
申请日：2006-02-09
申请人： Charles Vacanti , Yi Cao , Robert Langer , Joseph Vacanti , Keith Paige , Joseph Upton
发明人： Charles Vacanti , Yi Cao , Robert Langer , Joseph Vacanti , Keith Paige , Joseph Upton
IPC分类号： A61F2/08
CPC分类号： A61L27/3804 , A61F2/08 , A61L27/18 , A61L27/3604 , A61L27/3662 , A61L27/3817 , A61L27/3843 , A61L27/386 , A61L27/58 , A61L2430/10 , C08L67/04
摘要： Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
摘要翻译：结缔组织，包括新肌腱和韧带，已经使用可生物降解的合成支架构建，种子与细胞接种。支架优选由聚合物如聚乙醇酸 - 聚乳酸共聚物形成的可生物降解的纤维形成，并通过酶切消化或直接接种到外植体的组织培养皿中，从自体肌腱或韧带分离的细胞接种。然后手术移植细胞聚合物构建体以代替功能性肌腱或韧带的缺失部分。

3. 发明授权

US08835581B2 Neutral layer polymer composition for directed self assembly and processes thereof 有权
标题翻译：用于定向自组装的中性层聚合物组合物及其工艺
公开(公告)号：US08835581B2
公开(公告)日：2014-09-16
申请号：US13492125
申请日：2012-06-08
申请人： Hengpeng Wu , Orest Polishchuk , Yi Cao , SungEun Hong , Jian Yin , Guanyang Lin , Margareta Paunescu , Mark Neisser
发明人： Hengpeng Wu , Orest Polishchuk , Yi Cao , SungEun Hong , Jian Yin , Guanyang Lin , Margareta Paunescu , Mark Neisser
IPC分类号： C08F4/04 , C07C245/04
CPC分类号： C08F4/04 , C07C245/04 , C08F8/12 , C08F212/08 , C08F2800/20 , C08F2810/40 , G03F7/0002 , C08F220/14
摘要： The present invention relates to a novel polymeric composition comprising a novel polymer having two or more repeat units and a terminus having the structure (1): wherein R1 represents a C1-C20 substituted or unsubstituted alkyl group, w is a number from 1-8, X is oxygen (O) or nitrogen (N), and Rd is a reactive group. The invention also relates to a process for forming a pattern using the novel polymeric composition. The invention further relates to a process of making the novel polymer.
摘要翻译：本发明涉及包含具有两个或多个重复单元的新型聚合物和具有结构（1）的末端的新型聚合物组合物：其中R1表示C1-C20取代或未取代的烷基，w为1-8 ，X是氧（O）或氮（N），Rd是反应性基团。本发明还涉及使用新型聚合物组合物形成图案的方法。本发明还涉及制备该新型聚合物的方法。

4. 发明授权

US09052598B2 Compositions of neutral layer for directed self assembly block copolymers and processes thereof 有权
标题翻译：用于定向自组装嵌段共聚物的中性层组合物及其工艺
公开(公告)号：US09052598B2
公开(公告)日：2015-06-09
申请号：US14180848
申请日：2014-02-14
申请人： Hengpeng Wu , Yi Cao , SungEun Hong , Jian Yin , Margareta Paunescu , Mark O Neisser , Guanyang Lin
发明人： Hengpeng Wu , Yi Cao , SungEun Hong , Jian Yin , Margareta Paunescu , Mark O Neisser , Guanyang Lin
IPC分类号： G03F7/20 , C08L53/00 , C08F118/02 , C08L33/12 , C08F293/00 , G03F7/00 , B82Y10/00 , B82Y40/00
CPC分类号： G03F7/20 , B82Y10/00 , B82Y40/00 , C08F212/08 , C08F212/32 , C08F220/14 , C08F293/00 , C08L53/00 , C09D125/14 , C09D125/16 , G03F7/0002 , G03F7/2037
摘要： The present invention relates to novel processes for using the neutral layer compositions for aligning microdomains of directed self-assembling block copolymers (BCP). The processes are useful for fabrication of electronic devices. The novel processes comprise a step of forming a coating of the neutral layer from the neutral layer composition, wherein the neutral layer composition comprises at least one random copolymer having at least one unit of structure (1), at least one unit of structure (2) and at least one unit of structure (3) where R1 is selected from the group consisting of a C1-C8 alkyl, C1-C8 fluoroalkyl moiety, C1-C8 partially fluorinated alkyl, C4-C8 cycloalkyl, C4-C8 cyclofluoroalkyl, C4-C8 partially fluorinated cycloalkyl, and a C2-C8 hydroxyalkyl; R2, R3 and R5 are independently selected from a group consisting of H, C1-C4 alkyl, CF3 and F; R4 is selected from the group consisting of H, C1-C8 alkyl, C1-C8 partially fluorinated alkyl and C1-C8 fluoroalkyl, n ranges from 1 to 5, R6 is selected from the group consisting of H, F, C1-C8 alkyl and a C1-C8 fluoroalkyl and m ranges from 1 to 3.
摘要翻译：本发明涉及使用中性层组合物对准定向自组装嵌段共聚物（BCP）的微区域的新方法。该方法对于制造电子器件是有用的。该新方法包括从中性层组合物形成中性层的涂层的步骤，其中中性层组合物包含至少一种具有至少一个结构单元（1），至少一个结构单元（2）的无规共聚物）和至少一个结构单元（3），其中R 1选自C 1 -C 8烷基，C 1 -C 8氟烷基部分，C 1 -C 8部分氟化烷基，C 4 -C 8环烷基，C 4 -C 8环氟烷基，C 4 -C8部分氟化的环烷基，和C2-C8羟烷基; R2，R3和R5独立地选自H，C1-C4烷基，CF3和F; R 4选自H，C 1 -C 8烷基，C 1 -C 8部分氟化烷基和C 1 -C 8氟代烷基，n为1至5，R 6选自H，F，C 1 -C 8烷基和C 1 -C 8氟烷基，m为1至3。

5. 发明授权

US09040659B2 Methods and materials for removing metals in block copolymers 有权
标题翻译：用于去除嵌段共聚物中金属的方法和材料
公开(公告)号：US09040659B2
公开(公告)日：2015-05-26
申请号：US14175203
申请日：2014-02-07
申请人： Jian Yin , Hengpeng Wu , Muthiah Thiyagarajan , SungEun Hong , Mark Neisser , Yi Cao
发明人： Jian Yin , Hengpeng Wu , Muthiah Thiyagarajan , SungEun Hong , Mark Neisser , Yi Cao
IPC分类号： C08G64/00 , B05D5/00 , B01D15/36 , B01J45/00 , C08J3/00 , B01J39/04 , B01J41/04 , B05D1/00 , B05D3/00 , C08F6/02
CPC分类号： B05D5/00 , B01D15/361 , B01J39/05 , B01J41/07 , B01J45/00 , B05D1/005 , B05D3/00 , C08F6/02 , C08J3/00 , C08L53/00
摘要： The present invention relates to a method for treating a block copolymer solution, wherein the method comprises: providing a solution comprising a block copolymer in a non aqueous solvent; and, treating the solution to remove metals using an ion exchange resin. The invention also relates to a method of forming patterns using the treated block copolymer.
摘要翻译：本发明涉及一种处理嵌段共聚物溶液的方法，其中该方法包括：在非水溶剂中提供包含嵌段共聚物的溶液; 并使用离子交换树脂处理该溶液以除去金属。本发明还涉及使用经处理的嵌段共聚物形成图案的方法。

6. 发明申请

US20090246410A1 Manufacturing process of electrodes for electrolysis 有权
标题翻译：电解电极的制造工艺
公开(公告)号：US20090246410A1
公开(公告)日：2009-10-01
申请号：US12381962
申请日：2009-03-18
申请人： Yi Cao , Masashi Hosonuma
发明人： Yi Cao , Masashi Hosonuma
IPC分类号： C23C14/26
CPC分类号： C25B11/0426 , C23C14/16 , C23C14/325 , C23C14/5806 , C23C14/5853 , C25C7/02
摘要： A process for manufacturing electrodes for electrolysis, including the steps of forming an arc ion plating undercoating layer comprising valve metal or valve metal alloy including a crystalline tantalum component and a crystalline titanium component on the surface of the electrode substrate comprising valve metal or valve metal alloy, by an arc ion plating method; heat sintering the electrode substrate to transform only the tantalum component of the arc ion plating undercoating layer into an amorphous substance; and forming an electrode catalyst layer on the surface of the arc ion plating undercoating layer including the valve metal or valve metal alloy including the tantalum component transformed to the amorphous substance and the crystalline titanium component.
摘要翻译：一种制造电解电极的方法，包括以下步骤：在电极基材的表面上形成包括结晶钽组分和结晶钛组分的阀金属或阀金属合金的电弧离子镀底涂层，其包括阀金属或阀金属合金，通过电弧离子镀法; 对电极基板进行加热烧结，仅将电弧离子电镀底涂层的钽成分变形为无定形物质; 以及在包括转换成非晶体的钽成分和结晶钛成分的阀金属或阀金属合金的电弧离子电镀底涂层的表面上形成电极催化剂层。

7. 发明授权

US09291909B2 Composition comprising a polymeric thermal acid generator and processes thereof 有权
标题翻译：组合物，其包含聚合物热酸产生剂及其工艺
公开(公告)号：US09291909B2
公开(公告)日：2016-03-22
申请号：US13896936
申请日：2013-05-17
申请人： Hengpeng Wu , SungEun Hong , Yi Cao , Jian Yin , Margareta Paunescu , Muthiah Thiyagarajan
发明人： Hengpeng Wu , SungEun Hong , Yi Cao , Jian Yin , Margareta Paunescu , Muthiah Thiyagarajan
IPC分类号： G03F7/20 , C08F220/34 , G03F7/40 , C08F226/10 , C08F8/44 , C09D133/14 , C09D139/06 , G03F7/00 , H01L21/027 , G03F7/004 , G03F7/039
CPC分类号： G03F7/405 , C08F8/44 , C08F220/34 , C08F226/10 , C08L2201/54 , C09D133/14 , C09D139/06 , G03F7/0035 , G03F7/0048 , G03F7/0392 , G03F7/40 , H01L21/0273
摘要： The present invention relates a novel aqueous composition comprising polymeric thermal acid generator and a process of coating the novel composition onto photoresist pattern, thereby forming a layer of the polymeric thermal acid generator over the photoresist pattern. The polymeric thermal acid generator comprises a polymer having at least one repeating unit of structure 2; where R1 to R5 are independently chosen from the group consisting of H and C1-C6 alkyl; R6 is chosen from the group consisting of unsubstituted aryl, substituted aryl, alkyl (C1-C8) and fluoroalkyl (C1-C8) and W is a C2-C6 alkylene spacer.
摘要翻译：本发明涉及包含聚合物热酸发生剂的新型含水组合物和将该新组合物涂覆在光致抗蚀剂图案上的方法，由此在光致抗蚀剂图案上形成聚合物热酸发生剂层。聚合物热酸产生剂包括具有至少一个结构2的重复单元的聚合物; 其中R 1至R 5独立地选自H和C 1 -C 6烷基; R6选自未取代的芳基，取代的芳基，（C1-C8）烷基和氟烷基（C1-C8），W是C2-C6亚烷基间隔基。

8. 发明授权

US08691925B2 Compositions of neutral layer for directed self assembly block copolymers and processes thereof 有权
标题翻译：用于定向自组装嵌段共聚物的中性层组合物及其工艺
公开(公告)号：US08691925B2
公开(公告)日：2014-04-08
申请号：US13243640
申请日：2011-09-23
申请人： Hengpeng Wu , Yi Cao , SungEun Hong , Jian Yin , Margareta Paunescu , Mark O. Neisser , Guanyang Lin
发明人： Hengpeng Wu , Yi Cao , SungEun Hong , Jian Yin , Margareta Paunescu , Mark O. Neisser , Guanyang Lin
IPC分类号： C08F118/02 , G03F7/20 , C08L33/12
CPC分类号： G03F7/20 , B82Y10/00 , B82Y40/00 , C08F212/08 , C08F212/32 , C08F220/14 , C08F293/00 , C08L53/00 , C09D125/14 , C09D125/16 , G03F7/0002 , G03F7/2037
摘要： The present invention relates to novel neutral layer compositions and methods for using the compositions. The neutral layer composition comprises at least one random copolymer having at least one unit of structure (1), at least one unit of structure (2) and at least one unit of structure (3) where R1 is selected from the group consisting of a C1-C8 alkyl, C1-C8 fluoroalkyl moiety, C1-C8 partially fluorinated alkyl, C4-C8 cycloalkyl, C4-C8 cyclofluoroalkyl, C4-C8 partially fluorinated cycloalkyl, and a C2-C8 hydroxyalkyl; R2, R3 and R5 are independently selected from a group consisting of H, C1-C4 alkyl, CF3 and F; R4 is selected from the group consisting of H, C1-C8 alkyl, C1-C8 partially fluorinated alkyl and C1-C8 fluoroalkyl, n ranges from 1 to 5, R6 is selected from the group consisting of H, F, C1-C8 alkyl and a C1-C8 fluoroalkyl and m ranges from 1 to 3.
摘要翻译：本发明涉及新型中性层组合物和使用该组合物的方法。中性层组合物包含至少一种具有至少一个结构单元（1），至少一个结构单元（2）和至少一个结构单元（3）的无规共聚物，其中R1选自 C 1 -C 8烷基，C 1 -C 8氟烷基部分，C 1 -C 8部分氟化烷基，C 4 -C 8环烷基，C 4 -C 8环氟烷基，C 4 -C 8部分氟化环烷基和C 2 -C 8羟烷基; R2，R3和R5独立地选自H，C1-C4烷基，CF3和F; R 4选自H，C 1 -C 8烷基，C 1 -C 8部分氟化烷基和C 1 -C 8氟代烷基，n为1至5，R 6选自H，F，C 1 -C 8烷基和C 1 -C 8氟烷基，m为1至3。

9. 发明授权

US08489244B2 Method, controller and system for controlling the slug flow of a multiphase fluid 有权
标题翻译：用于控制多相流体的团状流的方法，控制器和系统
公开(公告)号：US08489244B2
公开(公告)日：2013-07-16
申请号：US12748310
申请日：2010-03-26
申请人： Yi Cao , Liyun Lao , Hoi Yeung
发明人： Yi Cao , Liyun Lao , Hoi Yeung
IPC分类号： G06F19/00
CPC分类号： B01D19/0063 , E21B43/12 , F17D1/005 , G05D7/0635 , Y10T137/0324 , Y10T137/7722
摘要： A method of controlling the flow of a multiphase fluid through a pipeline that includes a riser pipe with a choke valve comprises receiving multiple signals dependent on fluid flow properties from a plurality of sensors in the topside area of the riser pipe, analysing the signals to establish a vector of measurement weights, the product of the vector of measurement weights and a corresponding vector of the signal values of a given time being dependent on the severity of a slug flow forming in the system. Further signals dependent on fluid flow properties are received from the plurality of sensors in the topside area of the riser pipe. A set position for the choke valve is then determined from the product of the vector of measurement weights and further values of signals to restrict characteristics of the flow in the topside from moving towards a severely slugging flow regime.
摘要翻译：控制多相流体通过管道流动的方法包括具有阻流阀的提升管包括从提升管顶部区域中的多个传感器接收取决于流体流动特性的多个信号，分析信号以建立测量权重的向量，测量权重向量的乘积和给定时间的信号值的相应向量取决于系统中形成的段状流的严重性。取决于流体流动特性的进一步信号从提升管的顶侧区域中的多个传感器接收。然后，根据测量重量向量的乘积和信号的进一步值的乘积确定阻风门的设定位置，以限制顶部中的流动的特性，从而朝向严重的流动状态移动。

10. 发明申请

US20120028195A1 Composition for Coating over a Photoresist Pattern 有权
标题翻译：用于在光刻胶图案上涂覆的组合物
公开(公告)号：US20120028195A1
公开(公告)日：2012-02-02
申请号：US12845236
申请日：2010-07-28
申请人： Hengpeng Wu , Meng Li , Yi Cao , Jian Yin , DongKwan Lee , SungEun Hong , Margareta Paunescu
发明人： Hengpeng Wu , Meng Li , Yi Cao , Jian Yin , DongKwan Lee , SungEun Hong , Margareta Paunescu
IPC分类号： G03F7/20 , C09D5/00
CPC分类号： C09D183/08 , C08G77/26 , C08K5/09 , C08K5/544 , G03F7/405
摘要： The present invention relates to an aqueous composition for coating over a photoresist pattern comprising a first water soluble compound comprising at least a silicon moiety and at least one amino group, and a second compound comprising at least 1 carboxylic acid group. The invention further relates to processes for using the novel invention.
摘要翻译：本发明涉及一种用于在光致抗蚀剂图案上涂覆的水性组合物，其包含至少包含硅部分和至少一个氨基的第一水溶性化合物和包含至少1个羧酸基团的第二化合物。本发明还涉及使用本发明的方法。

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