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1. 发明授权

US06719725B2 Re-entry catheter 有权
标题翻译：再进入导管
公开(公告)号：US06719725B2
公开(公告)日：2004-04-13
申请号：US10308568
申请日：2002-12-03
申请人： Charles F. Milo , Matthew R. Selmon , Richard E. Hill , Fred H. Co , Ronald G. French
发明人： Charles F. Milo , Matthew R. Selmon , Richard E. Hill , Fred H. Co , Ronald G. French
IPC分类号： A61M5178
CPC分类号： A61B17/3207 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22044 , A61B2017/22077 , A61B2017/22095 , A61B2018/00392 , A61B2090/3925 , A61M25/01 , A61M2025/0096
摘要： Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other interventional and diagnostic catheters.
摘要翻译：通过将导线或其他穿透线从接近闭塞的点通过血管壁的内膜层和外膜层之间的内膜下间隔来跨越全部闭塞。导线前进到远离闭塞的点，然后偏转回血管内腔，通常使用偏转导管，该导管在定位于内膜下空间之前在引导线上前进。在将导丝返回到血管内腔之后，偏转导管可以被拉出并且导丝可用于引入其它介入和诊断导管。

2. 发明授权

US06511458B2 Vascular re-entry catheter 有权
标题翻译：血管再导管
公开(公告)号：US06511458B2
公开(公告)日：2003-01-28
申请号：US09765777
申请日：2001-01-19
申请人： Charles F. Milo , Matthew R. Selmon , Richard E. Hill , Fred H. Co , Ronald G. French
发明人： Charles F. Milo , Matthew R. Selmon , Richard E. Hill , Fred H. Co , Ronald G. French
IPC分类号： A61M5178
CPC分类号： A61B17/3207 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22044 , A61B2017/22077 , A61B2017/22095 , A61B2018/00392 , A61B2090/3925 , A61M25/01 , A61M2025/0096
摘要： Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other interventional and diagnostic catheters.
摘要翻译：通过将导线或其他穿透线从接近闭塞的点通过血管壁的内膜层和外膜层之间的内膜下间隔来跨越全部闭塞。导线前进到远离闭塞的点，然后偏转回血管内腔，通常使用偏转导管，该导管在定位于内膜下空间之前在引导线上前进。在将导丝返回到血管内腔之后，偏转导管可以被拉出并且导丝可用于引入其它介入和诊断导管。

3. 发明授权

US06235000B1 Apparatus for crossing total occlusion in blood vessels 有权
标题翻译：用于穿过血管中的全部闭塞的装置
公开(公告)号：US06235000B1
公开(公告)日：2001-05-22
申请号：US09440308
申请日：1999-11-17
申请人： Charles F. Milo , Matthew R. Selmon , Richard E. Hill , Fred H. Co , Ronald G. French
发明人： Charles F. Milo , Matthew R. Selmon , Richard E. Hill , Fred H. Co , Ronald G. French
IPC分类号： A61M5178
CPC分类号： A61B17/3207 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22044 , A61B2017/22077 , A61B2017/22095 , A61B2018/00392 , A61B2090/3925 , A61M25/01 , A61M2025/0096
摘要： Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other interventional and diagnostic catheters.
摘要翻译：通过将导线或其他穿透线从接近闭塞的点通过血管壁的内膜层和外膜层之间的内膜下间隔来跨越全部闭塞。导线前进到远离闭塞的点，然后偏转回血管内腔，通常使用偏转导管，该导管在定位于内膜下空间之前在引导线上前进。在将导丝返回到血管内腔之后，偏转导管可以被拉出并且导丝可用于引入其它介入和诊断导管。

4. 发明授权

US06231546B1 Methods and apparatus for crossing total occlusions in blood vessels 失效
标题翻译：穿过血管全闭塞的方法和装置
公开(公告)号：US06231546B1
公开(公告)日：2001-05-15
申请号：US09006563
申请日：1998-01-13
申请人： Charles F. Milo , Matthew R. Selmon , Richard E. Hill , Fred H. Co , Ronald G. French
发明人： Charles F. Milo , Matthew R. Selmon , Richard E. Hill , Fred H. Co , Ronald G. French
IPC分类号： A61M5178
CPC分类号： A61B17/3207 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22044 , A61B2017/22077 , A61B2017/22095 , A61B2018/00392 , A61B2090/3925 , A61M25/01 , A61M2025/0096
摘要： Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other interventional and diagnostic catheters.
摘要翻译：通过将导线或其他穿透线从接近闭塞的点通过血管壁的内膜层和外膜层之间的内膜下间隔来跨越全部闭塞。导线前进到远离闭塞的点，然后偏转回血管内腔，通常使用偏转导管，该导管在定位于内膜下空间之前在引导线上前进。在将导丝返回到血管内腔之后，偏转导管可以被拉出并且导丝可用于引入其它介入和诊断导管。

5. 发明申请

US20120053621A1 APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE 有权
标题翻译：用于密封血管内窥镜的装置和方法
公开(公告)号：US20120053621A1
公开(公告)日：2012-03-01
申请号：US13252061
申请日：2011-10-03
申请人： Celso J. Bagaoisan , Sieu Duong , Fred H. Co , Juan Domingo
发明人： Celso J. Bagaoisan , Sieu Duong , Fred H. Co , Juan Domingo
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00557 , A61B2017/00601 , A61B2017/00619 , A61B2017/00623 , A61B2017/00654 , A61B2017/00898
摘要： Apparatus and methods for sealing a puncture through tissue includes an introducer sheath sized for introduction into a puncture, cartridge sized for insertion into the introducer carrying a sealant, and a locking element for coupling the introducer sheath to the cartridge. When the cartridge is advanced into the introducer sheath, the locking element couples the introducer sheath to the cartridge such that subsequent retraction of the cartridge causes the introducer sheath to retract, thereby deploying the sealant from the cartridge within the puncture beyond the introducer sheath.
摘要翻译：用于密封通过组织的穿刺的装置和方法包括尺寸适于引入穿刺的引导器护套，尺寸适于插入到携带密封剂的引入器中的药筒，以及用于将引入器护套连接到药筒的锁定元件。当药筒推进到导引鞘中时，锁定元件将导引器鞘连接到药筒，使得药筒的后续缩回导致引导器护套缩回，从而将穿刺中的药筒的密封剂从引导器鞘部分展开。

6. 发明授权

US06860880B2 Electrothermal instrument for sealing and joining or cutting tissue 有权
标题翻译：用于密封和接合或切割组织的电热仪器
公开(公告)号：US06860880B2
公开(公告)日：2005-03-01
申请号：US10292727
申请日：2002-11-12
申请人： Michael R. Treat , Fred H. Co , George D. Hermann , Thomas A. Howell , Theodore R. Kucklick , Michelle Y. Monfort , Kenneth H. Mollenauer
发明人： Michael R. Treat , Fred H. Co , George D. Hermann , Thomas A. Howell , Theodore R. Kucklick , Michelle Y. Monfort , Kenneth H. Mollenauer
IPC分类号： A61B17/00 , A61B17/11 , A61B17/22 , A61B17/32 , A61B18/04 , A61B18/08 , A61B18/12 , A61B18/14 , A61B18/20 , A61F7/00 , A61B18/10
CPC分类号： A61B18/1445 , A61B10/02 , A61B17/04 , A61B17/32 , A61B17/320068 , A61B18/08 , A61B18/085 , A61B18/1402 , A61B18/20 , A61B2017/2945 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00136 , A61B2018/00214 , A61B2018/0022 , A61B2018/00345 , A61B2018/00404 , A61B2018/00595 , A61B2018/00601 , A61B2018/00619 , A61B2018/0063 , A61B2018/00666 , A61B2018/00684 , A61B2018/00702 , A61B2018/00726 , A61B2018/00761 , A61B2018/00791 , A61B2018/00886 , A61B2018/1226 , A61B2018/1266 , A61B2018/1412 , A61B2018/1432 , A61B2018/1455 , A61B2018/1861 , A61B2090/064 , A61F2007/0078
摘要： An instrument and method are provided for sealing and joining or hemostatically dividing tissue, which is particularly suitable for laparoscopic and endoscopic surgery. The instrument makes use of the controlled application of a combination of heat and pressure to seal adjacent tissues, to join adjacent tissues, or to anastomose tissues, whereby tissue is heated for an optimal time and at an optimal temperature under optimal pressure to maximize tissue seal strength while minimizing collateral tissue damage. The instrument of the present invention is lightweight and therefore portable, and is particularly useful in field conditions where a source of external power may not be readily available.
摘要翻译：提供了用于密封和接合或止血分离的组织的仪器和方法，其特别适用于腹腔镜和内窥镜手术。该仪器利用热和压力的组合的受控应用来密封相邻组织，连接相邻组织或吻合组织，由此组织被加热达最佳时间并且在最佳压力下在最佳温度下最大化组织密封强度，同时尽量减少旁路组织损伤。本发明的仪器轻便且便于携带，并且在外部电源不可能容易获得的现场条件下特别有用。

7. 发明授权

US6033361A Vascular retractor 失效
标题翻译：血管牵开器
公开(公告)号：US6033361A
公开(公告)日：2000-03-07
申请号：US867133
申请日：1997-06-02
申请人： Fred H. Co , Kevin H. Van Bladel
发明人： Fred H. Co , Kevin H. Van Bladel
IPC分类号： A61B17/00 , A61B17/02 , A61B19/00
CPC分类号： A61B17/00008 , A61B17/0218 , A61B2017/00778 , A61B2090/3614 , A61B90/50
摘要： A self-supporting retractor for holding open an anatomic space for performing endoscopic surgical procedures. The retractor includes a substantially rigid elongate member, having proximal and distal ends, and having an arch shape or "C" cross-section, defining a passage and longitudinal working window along the retractor. The distal end is preferably rounded or streamlined to facilitate insertion along a dissected space with minimized tissue trauma, and may include a hooded portion enclosing the passage at the distal end. The elongate member may include radially-cooperating segments or self-retaining edges to maximize the area of the space held open by the retractor. The retractor may include a handle or a pivotable finger grip on the proximal end to manipulate the retractor during use, and/or a curved handle to tent the incision providing access to the dissected space. The retractor may also include a channel member for an endoscope, integrally formed or pivotally attached to the retractor.
摘要翻译：一种自支撑牵开器，用于支撑用于进行内窥镜手术的解剖空间。牵开器包括基本上刚性的细长构件，其具有近端和远端，并且具有拱形或“C”横截面，沿着牵开器限定通道和纵向工作窗口。远端优选是圆形或流线型的，以便于沿着解剖空间以最小的组织创伤插入，并且可以包括在远端封闭通道的连接部分。细长构件可以包括径向配合的区段或自身保持边缘，以使由牵开器保持打开的空间的面积最大化。牵开器可以包括手柄或近端的可枢转手指手柄，以在使用过程中操纵牵开器，和/或弯曲的手柄以对切口提供进入到解剖空间的帐篷。牵开器还可以包括用于内窥镜的通道构件，整体形成或枢转地附接到牵开器。

8. 发明授权

US6004340A Balloon dissecting instruments 失效
标题翻译：气球解剖仪
公开(公告)号：US6004340A
公开(公告)日：1999-12-21
申请号：US963132
申请日：1997-10-28
申请人： George D. Hermann , Fred H. Co , Douglas S. Sutton
发明人： George D. Hermann , Fred H. Co , Douglas S. Sutton
IPC分类号： A61B17/00 , A61B1/00 , A61B17/02 , A61B17/22 , A61B17/32 , A61F2/958 , A61M25/01 , A61M25/12 , A61M29/02 , A61M29/00
CPC分类号： A61B17/00008 , A61B1/00082 , A61B1/00154 , A61B17/0218 , A61M25/0194 , A61M25/10 , A61M29/02 , A61B2017/00243 , A61B2017/00336 , A61B2017/00469 , A61B2017/00557 , A61B2017/22072 , A61B2017/320044 , A61B2017/320048 , A61M2025/09183 , A61M2025/1061 , A61M2025/1075 , A61M2025/1093 , A61M25/1002
摘要： Balloon loaded dissection devices with elongate balloons and a pushing member are disclosed for creating a tunnel alongside an elongate vessel in the body. The devices may utilize an elongate balloon of any suitable length which may be formed of an elastic or non-elastic material. The balloon may be of double walled construction and may be provided with a central lumen which may receive a guide rod, scope or other surgical instrument. The device may have a support tube secured to the inner wall of the balloon to provide columnar support for the apparatus. The support tube may have a transparent shroud attached to a distal end of the support tube. There is an open space between the distal end of the support tube and the end of the shroud allowing access to adjacent tissue. The shroud may perform blunt dissection and/or retraction to clear an open space for viewing or for performing surgical procedures. The support tube receives a scope or other surgical instrument and may have a stop member to translate pushing force applied to the scope to pushing force on the apparatus. By using the guide rod or scope as a pushing member the apparatus may be advanced alongside the vessel it is desired to dissect free from attached tissue. A balloon cover which may be elastic or resilient is provided to surround the balloon and facilitate compression of the balloon after it is deflated.
摘要翻译：公开了具有细长气囊和推动构件的气囊装载的解剖装置，用于在身体中的细长血管旁边形成隧道。这些装置可以利用可由弹性或非弹性材料形成的任何合适长度的细长气囊。球囊可以是双层结构，并且可以设置有可以容纳导杆，范围或其它外科器械的中心腔。该装置可以具有固定到球囊的内壁的支撑管，以为该装置提供柱状支撑。支撑管可以具有附接到支撑管的远端的透明罩。在支撑管的远端和护罩的端部之间存在允许进入相邻组织的开放空间。护罩可以执行钝性解剖和/或缩回以清除用于观察或执行外科手术的开放空间。支撑管接收镜架或其他手术器械，并且可具有止动构件以将施加到镜架的推力转换成对装置的推力。通过使用导杆或镜子作为推动构件，装置可以沿着容器前进，期望从附着的组织中解剖。可以具有弹性或弹性的气球盖被设置成围绕气球并且有助于在气囊收缩之后压缩气囊。

9. 发明授权

US5993472A Balloon dissecting instruments 失效
标题翻译：气球解剖仪
公开(公告)号：US5993472A
公开(公告)日：1999-11-30
申请号：US926796
申请日：1997-09-10
申请人： George D. Hermann , Fred H. Co , Douglas S. Sutton
发明人： George D. Hermann , Fred H. Co , Douglas S. Sutton
IPC分类号： A61B1/00 , A61B17/00 , A61B17/02 , A61B17/22 , A61B17/32 , A61F2/958 , A61M25/01 , A61M29/02 , A61M29/00
CPC分类号： A61B17/0218 , A61B1/00082 , A61B1/00154 , A61B1/32 , A61B17/00008 , A61M25/0194 , A61M29/02 , A61B2017/00243 , A61B2017/00557 , A61B2017/22072 , A61B2017/320044 , A61B2017/320048 , A61M2025/09183 , A61M2025/1093 , A61M25/10 , A61M25/1011
摘要： Balloon loaded dissection devices with elongate balloons and a pushing member are disclosed for creating a tunnel alongside an elongate vessel in the body. The devices may utilize an elongate balloon of any suitable length which may be formed of an elastic or non-elastic material. The balloon may be of double walled construction and may be provided with a central lumen which may receive a guide rod, scope or other surgical instrument. The device may have a support tube secured to the inner wall of the balloon to provide columnar support for the apparatus. The support tube receives the guide rod, scope or other surgical instrument and may have a stop member to translate pushing force applied to the guide rod or scope to pushing force on the apparatus. By using the guide rod or scope as a pushing member the apparatus may be advanced alongside the vessel it is desired to dissect free from attached tissue. A balloon cover which may be elastic or resilient is provided to surround the balloon and facilitate compression of the balloon after it is deflated. In an additional feature, the guide rod and/or tubular member are plastically bendable into a curved shape such that the balloon dissector may be adjusted into a curved shape.
摘要翻译：公开了具有细长气囊和推动构件的气囊装载的解剖装置，用于在身体中的细长血管旁边形成隧道。这些装置可以利用可由弹性或非弹性材料形成的任何合适长度的细长气囊。球囊可以是双层结构，并且可以设置有可以容纳导杆，范围或其它外科器械的中心腔。该装置可以具有固定到球囊的内壁的支撑管，以为该装置提供柱状支撑。支撑管接收导杆，镜或其它手术器械，并且可以具有止动构件，以将施加到导杆或镜架的推力平移到装置上的推力。通过使用导杆或镜子作为推动构件，装置可以沿着容器前进，期望从附着的组织中解剖。可以具有弹性或弹性的气球盖被设置成围绕气球并且有助于在气囊收缩之后压缩气囊。在另外的特征中，导杆和/或管状构件可塑性弯曲成弯曲形状，使得气囊解剖器可以调节成弯曲形状。

10. 发明授权

US09364206B2 Apparatus and methods for sealing a vascular puncture 有权
标题翻译：用于密封血管穿刺的装置和方法
公开(公告)号：US09364206B2
公开(公告)日：2016-06-14
申请号：US13252061
申请日：2011-10-03
申请人： Celso J. Bagaoisan , Sieu Duong , Fred H. Co , Juan Domingo
发明人： Celso J. Bagaoisan , Sieu Duong , Fred H. Co , Juan Domingo
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00557 , A61B2017/00601 , A61B2017/00619 , A61B2017/00623 , A61B2017/00654 , A61B2017/00898
摘要： Apparatus and methods for sealing a puncture through tissue includes an introducer sheath sized for introduction into a puncture, cartridge sized for insertion into the introducer carrying a sealant, and a locking element for coupling the introducer sheath to the cartridge. When the cartridge is advanced into the introducer sheath, the locking element couples the introducer sheath to the cartridge such that subsequent retraction of the cartridge causes the introducer sheath to retract, thereby deploying the sealant from the cartridge within the puncture beyond the introducer sheath.
摘要翻译：用于密封通过组织的穿刺的装置和方法包括尺寸适于引入穿刺的引导器护套，尺寸适于插入到携带密封剂的引入器中的药筒，以及用于将引入器护套连接到药筒的锁定元件。当药筒推进到导引鞘中时，锁定元件将导引器鞘连接到药筒，使得药筒的后续缩回导致引导器护套缩回，从而将穿刺中的药筒的密封剂从引导器鞘部分展开。

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