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1. 外观设计

USD889633S1 Loading track 有权
公开(公告)号：USD889633S1
公开(公告)日：2020-07-07
申请号：US29647907
申请日：2018-05-16
申请人： Cepheid
设计人： Ronald Chang , Steven M. Montgomery , Gregory Mote

2. 发明授权

US10525468B2 Fluid processing and control 有权
公开(公告)号：US10525468B2
公开(公告)日：2020-01-07
申请号：US15601725
申请日：2017-05-22
申请人： Cepheid
发明人： Douglas B. Dority , Ronald Chang
IPC分类号： G01N1/00 , B01L3/00 , G01N1/28 , G01N1/18 , G01N1/40
摘要： A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers. One or more of the chambers may be a processing chamber which includes two ports configured to selectively engage the at least one external port of the body, and a fluid processing material such as an enrichment material or a depletion material. In some embodiments, one or more chambers may include a separation channel, and an electric field may be applied across the separation channel.

3. 发明申请

US20180187243A1 METHODS AND APPARATUS FOR SEQUENTIAL AMPLIFICATION REACTIONS 审中-公开
公开(公告)号：US20180187243A1
公开(公告)日：2018-07-05
申请号：US15849125
申请日：2017-12-20
申请人： Cepheid
发明人： Joseph H. Smith , David H. Persing , Alan Wortman , Ronald Chang , David Swenson
IPC分类号： C12Q1/686 , B01L7/00 , C12Q1/689 , C12Q1/6848 , B01L3/00 , C12Q1/6851
CPC分类号： C12Q1/686 , B01L3/502738 , B01L7/52 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2400/0644 , C12Q1/6848 , C12Q1/6851 , C12Q1/689 , C12Q2565/629 , C12Q2547/101 , C12Q2537/149 , C12Q2537/143 , C12Q2565/101 , C12Q2527/107
摘要： The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.

4. 外观设计

USD804049S1 Molecular diagnostic system 有权
公开(公告)号：USD804049S1
公开(公告)日：2017-11-28
申请号：US29584368
申请日：2016-11-14
申请人： CEPHEID
设计人： Ronald Chang , Steven M. Montgomery , Gregory E. Mote

5. 发明申请

US20170252742A1 FLUID PROCESSING AND CONTROL 审中-公开
公开(公告)号：US20170252742A1
公开(公告)日：2017-09-07
申请号：US15601725
申请日：2017-05-22
申请人： Cepheid
发明人： Douglas B. DORITY , Ronald Chang
IPC分类号： B01L3/00 , G01N1/18 , G01N1/28 , G01N1/40
摘要： A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers. One or more of the chambers may be a processing chamber which includes two ports configured to selectively engage the at least one external port of the body, and a fluid processing material such as an enrichment material or a depletion material. In some embodiments, one or more chambers may include a separation channel, and an electric field may be applied across the separation channel.

6. 发明授权

US09446409B2 Method and apparatus for storing and dispensing reagent beads 有权
公开(公告)号：US09446409B2
公开(公告)日：2016-09-20
申请号：US14268682
申请日：2014-05-02
申请人： Cepheid
发明人： Ronald Chang , Douglas B. Dority , Steven Montgomery
IPC分类号： B01L9/00 , B23Q7/04 , G07F11/16 , B65H5/00 , B65H1/08 , B65H3/00 , B01L3/00 , B01J19/00 , B01L3/02 , G01N35/00
CPC分类号： B01L3/527 , B01J19/0046 , B01J2219/00468 , B01J2219/005 , B01J2219/00657 , B01L3/0289 , B01L2200/0647 , B01L2200/16 , G01N2035/00574 , Y10T436/25
摘要： Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In some embodiments, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge. The cover tape is insertable through the stripping gap to be pulled against the stripping edge to peel the cover tape from the bead carrier to move the wells of the bead carrier inside the channel toward the dispense opening and expose the wells individually to dispense the reagent beads.

7. 发明授权

US09322052B2 Cartridge for conducting a chemical reaction 有权
标题翻译：用于进行化学反应的墨盒
公开(公告)号：US09322052B2
公开(公告)日：2016-04-26
申请号：US14218517
申请日：2014-03-18
申请人： Cepheid
发明人： Kurt E. Petersen , William McMillan , Farzad Pourahmadi , Ronald Chang , Douglas B. Dority
IPC分类号： C12Q1/68 , G01N33/53 , B01L3/00 , B01L7/00
CPC分类号： B01L7/52 , B01L3/502 , B01L2200/10 , B01L2300/0654 , B01L2300/0681 , B01L2300/0858 , B01L2300/087 , B01L2300/123 , B01L2300/14 , B01L2300/168 , B01L2300/18 , B01L2400/0487 , B01L2400/0622 , B01L2400/0644 , C12Q1/6844 , G01N33/5302 , Y10T436/25 , Y10T436/25375 , Y10T436/2575
摘要： A cartridge for conducting a chemical reaction includes a body having at least one flow path formed therein. The cartridge also includes a reaction vessel extending from the body for holding a reaction mixture for chemical reaction and optical detection. The vessel comprises a rigid frame defining the side walls of a reaction chamber. The frame includes at least one channel connecting the flow path to the chamber. The vessel also includes flexible films or sheets attached to opposite sides of the rigid frame to form opposing major walls of the chamber. In addition, at least two of the side walls are optically transmissive and angularly offset from each to permit real-time optical detection of analyte in the reaction chamber.
摘要翻译：用于进行化学反应的药筒包括具有形成在其中的至少一个流路的主体。药筒还包括从身体延伸的反应容器，用于保持用于化学反应和光学检测的反应混合物。容器包括限定反应室侧壁的刚性框架。该框架包括连接到该腔室的流动路径的至少一个通道。容器还包括附接到刚性框架的相对侧的柔性膜或片，以形成腔室的相对的主壁。此外，至少两个侧壁是光学透射的并且与每个侧壁成角度地偏移以允许对反应室中的分析物的实时光学检测。

8. 发明申请

US20140093430A1 METHOD FOR FABRICATING A REACTION VESSEL 有权
标题翻译：制造反应容器的方法
公开(公告)号：US20140093430A1
公开(公告)日：2014-04-03
申请号：US13632945
申请日：2012-10-01
申请人： Cepheid
发明人： Ronald Chang , Douglas Dority
IPC分类号： G01N21/75
CPC分类号： G01N21/75 , B01J19/0093 , B01J2219/00783 , B01J2219/0081 , B01J2219/00822 , B01J2219/00828 , B01J2219/00833 , B01J2219/00871 , B01J2219/00873 , B01J2219/00961 , B01J2219/0097 , B01J2219/00986 , B01L3/505 , B01L3/508 , B01L7/52 , B01L2300/042 , B01L2300/0809 , B01L2300/0858 , B01L2300/168 , B01L2300/1805 , F28D2021/0077 , F28F3/12 , F28F21/04 , F28F2280/10 , G01N21/0303 , G01N21/0332 , G01N2035/00326
摘要： A reaction vessel having a reaction chamber for holding a sample is fabricated by producing a housing having a rigid frame defining the minor walls of the chamber. The housing also defines a port for introducing fluid into the chamber. At least one sheet or film is attached to the rigid frame to form at least one major wall of the chamber. In preferred embodiments, two sheets or films are attached to opposite sides of the rigid frame to form two opposing major walls of the chamber, the major walls being connected to each other by the minor walls.
摘要翻译：具有用于保持样品的反应室的反应容器通过制造具有限定室的小壁的刚性框架的壳体来制造。壳体还限定了用于将流体引入腔室的端口。至少一个片或薄膜连接到刚性框架以形成腔室的至少一个主壁。在优选实施例中，两个片或膜连接到刚性框架的相对侧面以形成腔室的两个相对的主壁，主壁通过次壁彼此连接。

9. 外观设计

USD908301S1 Waste receptacle with lid 有权
公开(公告)号：USD908301S1
公开(公告)日：2021-01-19
申请号：US29647904
申请日：2018-05-16
申请人： Cepheid
设计人： Ronald Chang , Steven M. Montgomery , Gregory Mote , Brian Bliven , Paul Jordan

10. 外观设计

USD802786S1 Molecular diagnostic system 有权
公开(公告)号：USD802786S1
公开(公告)日：2017-11-14
申请号：US29584373
申请日：2016-11-14
申请人： CEPHEID
设计人： Ronald Chang , Steven M. Montgomery , Gregory E. Mote

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