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    • 10. 发明授权
    • Cleaning and disinfecting agent containing an N-substituted propylene
glutamic acid or derivative thereof, and an antimicrobially active
compound
    • 包含N-取代的丙烯谷氨酸或其衍生物的清洁和消毒剂和抗微生物活性化合物
    • US5403505A
    • 1995-04-04
    • US923969
    • 1992-11-12
    • Klaus HachmannKarlheinz DischKlaus-Peter BansemirHubert SchwiddenStephanie KauppCarsten FrieseRudolf LehmannHans T. Leinen
    • Klaus HachmannKarlheinz DischKlaus-Peter BansemirHubert SchwiddenStephanie KauppCarsten FrieseRudolf LehmannHans T. Leinen
    • A61L2/18C11D1/645C11D3/48
    • C11D3/48A61L2/18C11D1/645
    • An aqueous cleaning and disinfecting concentrate comprisingA) at lease one reaction product ofa) an N-substituted propylene diamine of formula IR.sup.1 --NH--(CH.sub.2).sub.3 --NH.sub.2 (I) in which R.sup.1 is a C.sub.8 -C.sub.18 alkyl group andb) glutamic acid or a glutamic acid derivative of formula IIR.sub.2 --O--CO--(CH.sub.2).sub.2 --CH(NH.sub.2)--COOH (II) in which R.sup.2 is hydrogen or a C.sub.1 -C.sub.4 alkyl group, wherein the said reaction product is optionally ethoxylated and/or propoxylated, and is optionally in the form of a salt with an organic or inorganic acid;B) at least one of the following antimicrobially active compounds:i) a quaternary ammonium compound of formula III ##STR1## in which R.sup.3 and R.sup.4 independently of one another represent alkyl radicals containing 1 to 3 carbon atoms or benzyl radicals, or halogenated or alkylated benzyl radicals containing 6 to 22 carbon atoms, and X.sup.- is an anion;ii) a phenol;iii) a biguanide;(iv) a quaternary phosphonium compound of formula IV ##STR2## in which R.sup.7, R.sup.8, R.sup.9 and R.sup.10 are each independently an alkyl, alkenyl, aryl, or alkaryl group having from 1 to 16 carbon atoms, and Y.sup.- is an anion; andC) at least one low foaming surfactant.The invention also relates to the diluted concentrates, and to the method of use of the diluted concentrates, especially for the disinfection of medical equipment.
    • PCT No.PCT / EP91 / 00400 Sec。 371日期:1992年11月12日 102(e)日期1992年11月12日PCT 1991年3月4日PCT公布。 出版物WO91 / 日本1991年9月19日。一种水性清洁和消毒浓缩物,其包含A)至少一种反应产物,其a)N-取代的丙二胺,式I R1-NH-(CH2)3-NH2(Ⅰ),其中R1是 C 8 -C 18烷基和b)谷氨酸或式II的R 2 -O-CO-(CH 2)2 -CH(NH 2)-COOH(II)的谷氨酸衍生物,其中R 2是氢或C 1 -C 4烷基 基团,其中所述反应产物任选被乙氧基化和/或丙氧基化,并且任选地是与有机或无机酸形式的盐; B)至少一种以下抗微生物活性化合物:i)式III的季铵化合物(III),其中R 3和R 4彼此独立地表示含有1至3个碳原子的烷基或苄基,或 含有6-22个碳原子的卤代或烷基化苄基,X-是阴离子; ii)苯酚; iii)双胍; (iv)式IV的季鏻化合物其中R 7,R 8,R 9和R 10各自独立地为具有1至16个碳原子的烷基,烯基,芳基或烷芳基,Y-为 阴离子 和C)至少一种低发泡表面活性剂。 本发明还涉及稀释浓缩物,以及稀释浓缩物的使用方法,特别是用于医疗设备的消毒。