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    • 4. 发明授权
    • Sutureless methods for laceration closure
    • 缝合闭合方法
    • US08197507B2
    • 2012-06-12
    • US12353966
    • 2009-01-14
    • Pablo E. GarciaBryan ChavezJomayon Hill
    • Pablo E. GarciaBryan ChavezJomayon Hill
    • A61B17/08
    • A61B17/085A61F9/04
    • Tissue lacerations are closed using a vacuum cup applied to the tissue surface having a tissue-abutting, optically transparent mesh surface that under vacuum conforms with the tissue surface, apposing edges of the wound, and is optionally loaded with a bandage comprising a chitosan film and a collagen backing. An eye tissue surface wound is closed without sutures by closing the wound with a bioadhesive, biocompatible sclera or cornea wound patch comprising a chitosan film and a collagen backing, wherein the backing is bonded to the film without adhesive and protects the film against dissociation when the patch is exposed to a physiological fluid, and the film adheres to the sclera sufficient to retain apposed edges of the wound.
    • 使用施加到组织表面的真空杯封闭组织撕裂,所述真空杯具有组织邻接的光学透明的网眼表面,其在真空下符合组织表面,附着伤口的边缘,并且任选地装载有包含壳聚糖膜的绷带 胶原蛋白背衬。 通过用包含壳聚糖膜和胶原背衬的生物粘附性,生物相容性巩膜或角膜伤口贴片闭合伤口来关闭眼组织表面伤口,其中背衬与胶粘剂粘合到膜上并保护膜不被解离时 贴片暴露于生理液体,并且该膜粘附到巩膜以足以保留伤口的边缘。