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1. 发明授权

US09682082B2 Combinations of AKT and MEK inhibitor compounds, and methods of use 有权
公开(公告)号：US09682082B2
公开(公告)日：2017-06-20
申请号：US14009320
申请日：2012-03-30
申请人： Brian Lee , Kui Lin , Michelle Nannini , Elizabeth Punnoose , Deepak Sampath
发明人： Brian Lee , Kui Lin , Michelle Nannini , Elizabeth Punnoose , Deepak Sampath
IPC分类号： A61K31/517 , A61K31/165 , A61K31/4402 , A61K45/06 , C07D239/70 , A61K31/166 , A61K31/4523
CPC分类号： A61K31/517 , A61K31/165 , A61K31/166 , A61K31/4402 , A61K31/4523 , A61K45/06 , C07D239/70 , A61K2300/00
摘要： The invention provides combinations comprising a) compound of formula I: (formula I), or a pharmaceutically acceptable salt thereof; and another agent selected from GDC-0973, PD-0325901, or a pharmaceutically acceptable salt thereof. The combinations are particularly useful for treating hyperproliferative disorders, such as cancer.

2. 发明申请

US20140155372A1 COMBINATIONS OF AKT AND MEK INHIBITOR COMPOUNDS, AND METHODS OF USE 有权
标题翻译： AKT和MEK抑制剂化合物的组合及其使用方法
公开(公告)号：US20140155372A1
公开(公告)日：2014-06-05
申请号：US14009320
申请日：2012-03-30
申请人： Brian Lee , Kui Lin , Michelle Nannini , Elizabeth Punnoose , Deepak Sampath
发明人： Brian Lee , Kui Lin , Michelle Nannini , Elizabeth Punnoose , Deepak Sampath
IPC分类号： A61K31/517 , A61K31/166 , A61K31/4523
CPC分类号： A61K31/517 , A61K31/165 , A61K31/166 , A61K31/4402 , A61K31/4523 , A61K45/06 , C07D239/70 , A61K2300/00
摘要： The invention provides combinations comprising a) compound of formula I: (formula I), or a pharmaceutically acceptable salt thereof; and another agent selected from GDC-0973, PD-0325901, or a pharmaceutically acceptable salt thereof. The combinations are particularly useful for treating hyperproliferative disorders, such as cancer.
摘要翻译：本发明提供组合，其包含a）式I化合物：（式I）或其药学上可接受的盐; 和选自GDC-0973，PD-0325901或其药学上可接受的盐的另一种药剂。这些组合对于治疗过度增殖性疾病如癌症特别有用。

3. 发明授权

US08726103B2 Visual outage management tool 失效
标题翻译：视觉中断管理工具
公开(公告)号：US08726103B2
公开(公告)日：2014-05-13
申请号：US12962215
申请日：2010-12-07
申请人： Brian Lee
发明人： Brian Lee
IPC分类号： G06F11/00
CPC分类号： G06F11/328 , G06F11/3006 , G06F11/3017 , G06F11/302 , G06F11/3055 , G06Q10/06
摘要： Described herein are systems related to a visual tool for providing a dynamic and accessible collaborative environment during a production outage or network downtime. An outage management tool comprising a server application tool receiving and storing monitoring data related to an operation of a network and application-level components of the network, wherein the monitoring data includes outage information corresponding to one of the network and the application-level components, and a visualization tool generating an interactive representation of the network including the outage information, the visualization tool and generating, in response to a request, an adjusted interactive representation of the network including application-level components affected by an outage and event traffic related to the outage.
摘要翻译：这里描述的是与可视化工具相关的系统，用于在生产中断或网络停机期间提供动态和可访问的协作环境。一种中断管理工具，包括服务器应用工具，其接收和存储与网络的操作和网络的应用级组件相关的监控数据，其中所述监控数据包括与所述网络和所述应用级组件之一相对应的中断信息，以及可视化工具，其生成包括所述中断信息，所述可视化工具的所述网络的交互式表示，并响应于所述请求生成所述网络的经调整的交互式表示，所述交互式表示包括由与所述中断相关的中断和事件流量影响的应用级组件停电

4. 发明授权

US08541247B2 Non-volatile memory cell with lateral pinning 失效
标题翻译：具有侧向锁定的非易失性存储单元
公开(公告)号：US08541247B2
公开(公告)日：2013-09-24
申请号：US12973536
申请日：2010-12-20
申请人： Haiwen Xi , Antoine Khoueir , Brian Lee , Patrick J. Ryan
发明人： Haiwen Xi , Antoine Khoueir , Brian Lee , Patrick J. Ryan
IPC分类号： H01L27/115
CPC分类号： H01L43/08 , B82Y40/00 , G11C11/161 , G11C11/1675 , H01F10/3254 , H01F10/3272 , H01F10/329 , H01F41/303 , H01L43/12
摘要： An apparatus and associated method for a non-volatile memory cell, such as an STRAM cell. In accordance with various embodiments, a magnetic free layer is laterally separated from an antiferromagnetic layer (AFM) by a non-magnetic spacer layer and medially separated from a synthetic antiferromagnetic layer (SAF) by a magnetic tunneling junction. The AFM pins the magnetization of the SAF through contact with a pinning region of the SAF that laterally extends beyond the magnetic tunneling junction.
摘要翻译：用于非易失性存储器单元（例如STRAM单元）的装置和相关方法。根据各种实施例，无磁性层通过非磁性间隔层与反铁磁层（AFM）横向分离，并通过磁性隧道结从中间分离的合成反铁磁层（SAF）。 AFM通过与SAF的钉扎区域的接触来引导SAF的磁化，该区域横向延伸超过磁性隧道结。

5. 发明授权

US08508981B2 Apparatus for variable resistive memory punchthrough access method 有权
标题翻译：用于可变电阻存储器穿透访问方法的装置
公开(公告)号：US08508981B2
公开(公告)日：2013-08-13
申请号：US13478174
申请日：2012-05-23
申请人： Maroun Georges Khoury , Hongyue Liu , Brian Lee , Andrew John Gjevre Carter
发明人： Maroun Georges Khoury , Hongyue Liu , Brian Lee , Andrew John Gjevre Carter
IPC分类号： G11C11/00
CPC分类号： G11C11/1675 , G11C11/1659
摘要： Variable resistive punchthrough access methods are described. The methods include switching a variable resistive data cell from a high resistance state to a low resistance state by passing a write current through the magnetic tunnel junction data cell in a first direction. The write current is provided by a transistor being electrically coupled to the variable resistive data cell and a source line. The write current passes through the transistor in punchthrough mode.
摘要翻译：描述了可变电阻穿透访问方法。所述方法包括通过使写入电流沿着第一方向通过磁性隧道结数据单元，将可变电阻数据单元从高电阻状态切换到低电阻状态。写入电流由电耦合到可变电阻数据单元和源极线的晶体管提供。写入电流在穿通模式下通过晶体管。

6. 发明授权

US08448766B2 Bi-directional clutch with staggered roller elements 有权
标题翻译：具有交错滚子元件的双向离合器
公开(公告)号：US08448766B2
公开(公告)日：2013-05-28
申请号：US12818751
申请日：2010-06-18
申请人： Tomas Smetana , Brian Lee
发明人： Tomas Smetana , Brian Lee
IPC分类号： F16D15/00 , F16D41/06
CPC分类号： F16D41/088 , F16D15/00
摘要： A coupling having at least two concentric rings, each having a circumferential surface and a recess, and at least two roller elements. The roller elements are each disposed in a channel formed by the circumferential surface of one of the rings and the recess of another of the rings. In some example embodiments of the invention, the coupling includes a coupling member with a bearing surface, at least one of the rings includes a split and the split ring is urged against the bearing surface when there is relative rotation between the rings. The coupling member is, for example, a shaft or a gear.
摘要翻译：具有至少两个同心环的联接器，每个具有圆周表面和凹槽，以及至少两个滚子元件。辊元件各自设置在由一个环的圆周表面和另一个环的凹部形成的通道中。在本发明的一些示例性实施例中，联接器包括具有支承表面的联接构件，至少一个环包括开口，并且当环之间存在相对旋转时，开口环被推靠在支承表面上。联接构件例如是轴或齿轮。

7. 发明申请

US20120120628A1 MODULAR FLAT-PANEL MONITOR STAND 有权
标题翻译：模块化平板监视器
公开(公告)号：US20120120628A1
公开(公告)日：2012-05-17
申请号：US13386428
申请日：2009-07-22
申请人： Robert P Bliven , Jacques Gagne , Kenneth G. Robertson , Brian Lee , Brian David Perry
发明人： Robert P Bliven , Jacques Gagne , Kenneth G. Robertson , Brian Lee , Brian David Perry
IPC分类号： H05K7/02 , F16L3/23 , H05K7/00
CPC分类号： G06F1/1601 , F16M11/041 , F16M11/10 , F16M13/00
摘要： A flat-panel display stand in accordance with the present invention includes a modular assembly for supporting a display on a horizontal surface so that the display tilt can be adjusted by the user. The stand has a modular design with only two modules: a retainer clip and supporting leg that are uniquely hinged together and connected to the rear of the display.
摘要翻译：根据本发明的平板显示支架包括用于在水平表面上支撑显示器的模块化组件，使得显示器倾斜度可以由用户调节。支架具有仅具有两个模块的模块化设计：保持夹和支撑腿，其独特地铰接在一起并连接到显示器的后部。

8. 发明授权

US08065204B2 System and method for software integration and factory deployment 失效
标题翻译：用于软件集成和工厂部署的系统和方法
公开(公告)号：US08065204B2
公开(公告)日：2011-11-22
申请号：US11541433
申请日：2006-09-29
申请人： Eric Gerzymisch , Vijayanand Muralidhar Kallianpur , Sean Patrick Kennedy , Masafumi Kuboyama , Brian Lee , Yoshiro Muraoka , Victor Glenn Reha
发明人： Eric Gerzymisch , Vijayanand Muralidhar Kallianpur , Sean Patrick Kennedy , Masafumi Kuboyama , Brian Lee , Yoshiro Muraoka , Victor Glenn Reha
IPC分类号： A01K5/02 , G06F17/50 , G06G1/14 , G06Q20/00 , G06Q30/00 , G06Q10/00
CPC分类号： G06F8/61 , G06Q10/087 , G06Q10/0875 , G06Q20/203 , G06Q30/0621 , G06Q30/0623 , G06Q30/0631
摘要： A software management database contains data structures supporting computer software provisioning for a range of CTO/BTO variations, language variations, region variations, and operating system variations.
摘要翻译：软件管理数据库包含支持针对一系列CTO / BTO变体，语言变化，区域变化和操作系统变化的计算机软件配置的数据结构。

9. 发明授权

US08050092B2 NAND flash memory with integrated bit line capacitance 有权
标题翻译：具有集成位线电容的NAND闪存
公开(公告)号：US08050092B2
公开(公告)日：2011-11-01
申请号：US12474463
申请日：2009-05-29
申请人： Chulmin Jung , Harry Hongyue Liu , Brian Lee , Yong Lu , Dadi Setiadi
发明人： Chulmin Jung , Harry Hongyue Liu , Brian Lee , Yong Lu , Dadi Setiadi
IPC分类号： G11C11/34 , G11C11/24
CPC分类号： G11C11/005 , G11C16/26 , G11C2216/14
摘要： Method and apparatus for outputting data from a memory array having a plurality of non-volatile memory cells arranged into rows and columns. In accordance with various embodiments, charge is stored in a volatile memory cell connected to the memory array, and the stored charge is subsequently discharged from the volatile memory cell through a selected column. In some embodiments, the volatile memory cell is a dynamic random access memory (DRAM) cell from a row of the cells with each DRAM cell along the row coupled to a respective column in the memory array, and each column of non-volatile memory cells comprises Flash memory cells connected in a NAND configuration.
摘要翻译：用于从具有排列成行和列的多个非易失性存储单元的存储器阵列输出数据的方法和装置。根据各种实施例，电荷被存储在连接到存储器阵列的易失性存储单元中，并且随后通过所选择的列从易失性存储器单元中释放存储的电荷。在一些实施例中，易失性存储器单元是来自单元行的动态随机存取存储器（DRAM）单元，每个DRAM单元沿着与存储器阵列中的相应列耦合的行，并且每列非易失性存储单元包括以NAND配置连接的闪存单元。

10. 发明授权

US07997159B2 Gear selection assembly with nested differentially rotatable tube 有权
标题翻译：齿轮选择组件采用嵌套差速转动管
公开(公告)号：US07997159B2
公开(公告)日：2011-08-16
申请号：US11924081
申请日：2007-10-25
申请人： Jeffrey Hemphill , Mavinkal Jayaram , Brian Lee , Robert Southam
发明人： Jeffrey Hemphill , Mavinkal Jayaram , Brian Lee , Robert Southam
IPC分类号： F16H59/00 , F16H61/00 , F16H63/00 , F16H3/38 , F16H3/08 , F16H3/44
CPC分类号： F16H3/083 , F16D21/04 , F16H63/30 , F16H2063/3096 , Y10T74/19279 , Y10T74/19284 , Y10T74/1946 , Y10T74/19465 , Y10T74/20018 , Y10T74/20024
摘要： The present invention broadly comprises a gear selector assembly including a tube with at least one engagement feature, arranged to be disposed within a drive shaft for a transmission, the transmission including at least one gear and the drive shaft including at least one gear actuation assembly; and a differential rotation element coupled with the tube and arranged to be coupled with the drive shaft so that the tube is differentially rotatable with respect to the drive shaft. The tube is arranged to differentially rotate such that the engagement feature engages the actuation assembly and the transmission engages a respective gear from the at least one gear. The assembly includes a means for displacing a portion of the differential rotation element such that the tube axially and rotationally displaces with respect to the drive shaft. The portion axially and rotationally engages with an interface element to controllably position the tube.
摘要翻译：本发明广泛地包括齿轮选择器组件，其包括具有至少一个接合特征的管，其布置成设置在用于变速器的驱动轴内，所述变速器包括至少一个齿轮，并且所述驱动轴包括至少一个齿轮致动组件; 以及与所述管连接并且布置成与所述驱动轴联接的差速旋转元件，使得所述管相对于所述驱动轴可差速转动。管被布置成差异地旋转，使得接合特征接合致动组件，并且变速器接合来自至少一个齿轮的相应齿轮。组件包括用于移动差速旋转元件的一部分的装置，使得管相对于驱动轴轴向和旋转地移位。该部分轴向和旋转地接合界面元件以可控制地定位管。

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