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1. 发明授权

US06689586B2 Nucleotide sequences which code for the CcpA2 gene 失效
标题翻译：编码CcpA2基因的核苷酸序列
公开(公告)号：US06689586B2
公开(公告)日：2004-02-10
申请号：US09938642
申请日：2001-08-27
申请人： Bettina Moeckel , Caroline Kreutzer , Thomas Hermann , Mike Garwick , Achim Marx , Walter Pfefferle
发明人： Bettina Moeckel , Caroline Kreutzer , Thomas Hermann , Mike Garwick , Achim Marx , Walter Pfefferle
IPC分类号： C12P2106
CPC分类号： C07K14/34 , C12P13/08
摘要： The invention relates to polynucleotides corresponding to the ccpA2 gene and which encode a CcpA2 catabolite control protein, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having CcpA2 catabolite control activity.
摘要翻译：本发明涉及对应于ccpA2基因并且编码CcpA2分解代谢物控制蛋白质的多核苷酸，产生L-氨基酸的方法，以及筛选编码具有CcpA2分解代谢物控制活性的蛋白质的多核苷酸的方法。

2. 发明授权

US07105321B2 Nucleotide sequences which code for the ccpA2 gene 有权
标题翻译：编码ccpA2基因的核苷酸序列
公开(公告)号：US07105321B2
公开(公告)日：2006-09-12
申请号：US10724827
申请日：2003-12-02
申请人： Bettina Moeckel , Caroline Kreutzer , Thomas Hermann , Mike Farwick , Achim Marx , Walter Pfefferle
发明人： Bettina Moeckel , Caroline Kreutzer , Thomas Hermann , Mike Farwick , Achim Marx , Walter Pfefferle
IPC分类号： C12P13/04 , C12P21/06 , C12P13/06 , C12N1/20 , C12N15/00
CPC分类号： C07K14/34 , C12P13/08
摘要： The invention relates to polynucleotides corresponding to the ccpA2 gene and which encode a CcpA2 catabolite control protein, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having CcpA2 catabolite control activity.
摘要翻译：本发明涉及对应于ccpA2基因并且编码CcpA2分解代谢物控制蛋白质的多核苷酸，产生L-氨基酸的方法，以及筛选编码具有CcpA2分解代谢物控制活性的蛋白质的多核苷酸的方法。

3. 发明申请

US20050282259A1 Nucleotide sequences for encoding of the lysR2-gene 失效
标题翻译：编码lysR2基因的核苷酸序列
公开(公告)号：US20050282259A1
公开(公告)日：2005-12-22
申请号：US11178485
申请日：2005-07-12
申请人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
发明人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
IPC分类号： C07K14/34 , C12N1/21 , C12N15/31 , C12P13/08
CPC分类号： C12P13/08 , C07K14/34
摘要： Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the lysR2 gene is present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.
摘要翻译：分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同的多核苷酸，b）多核苷酸，其编码多肽，其包含与SEQ ID No.2的氨基酸序列至少70％的程度相同的氨基酸序列，c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少lysR2基因存在于减毒形式，以及使用多核苷酸序列作为杂交探针。

4. 发明授权

US07416863B2 Nucleotide sequences for encoding of the lysR2-gene 失效
标题翻译：编码lysR2基因的核苷酸序列
公开(公告)号：US07416863B2
公开(公告)日：2008-08-26
申请号：US11178485
申请日：2005-07-12
申请人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
发明人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
IPC分类号： C12P19/34
CPC分类号： C12P13/08 , C07K14/34
摘要： Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c),and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the lysR2 gene is present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.
摘要翻译：分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同的多核苷酸，b）多核苷酸，其编码多肽，其包含与SEQ ID No.2的氨基酸序列至少70％的程度相同的氨基酸序列，c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少lysR2基因存在于减毒形式，以及使用多核苷酸序列作为杂交探针。

5. 发明申请

US20060019357A1 Nucleotide sequences which code for the rpsL gene 审中-公开
公开(公告)号：US20060019357A1
公开(公告)日：2006-01-26
申请号：US11197380
申请日：2005-08-05
申请人： Bettina Moeckel , Brigitte Bathe , Stefan Hans , Caroline Kreutzer , Thomas Hermann , Walter Pfefferle , Michael Binder
发明人： Bettina Moeckel , Brigitte Bathe , Stefan Hans , Caroline Kreutzer , Thomas Hermann , Walter Pfefferle , Michael Binder
IPC分类号： C07H21/04 , C12P21/06 , C12P13/08 , C12N9/10 , C12N15/74 , C12N1/21
CPC分类号： C07K14/34
摘要： An isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the rpsL gene is present in enhanced form, as well as the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.

6. 发明授权

US06939695B2 Nucleotide sequences which code for the rpsL gene 有权
标题翻译：编码rpsL基因的核苷酸序列
公开(公告)号：US06939695B2
公开(公告)日：2005-09-06
申请号：US10075460
申请日：2002-02-15
申请人： Bettina Moeckel , Brigitte Bathe , Stefan Hans , Caroline Kreutzer , Thomas Hermann , Walter Pfefferle , Michael Binder
发明人： Bettina Moeckel , Brigitte Bathe , Stefan Hans , Caroline Kreutzer , Thomas Hermann , Walter Pfefferle , Michael Binder
IPC分类号： C07K14/34 , C12N15/31 , C12P13/04 , C07H21/04
CPC分类号： C07K14/34
摘要： An isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the rpsL gene is present in enhanced form, as well as the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
摘要翻译：一种分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同的多核苷酸，b）编码多肽的多核苷酸，其包含与SEQ ID No.2的氨基酸序列至少70％相同的氨基酸序列，c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少存在rpsL基因增强形式，以及使用包含根据本发明的序列的多核苷酸作为杂交探针。

7. 发明授权

US06902916B2 Nucleotide sequences coding for the 1ysR1 gene 失效
标题翻译：编码1ysR1基因的核苷酸序列
公开(公告)号：US06902916B2
公开(公告)日：2005-06-07
申请号：US09903770
申请日：2001-07-13
申请人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
发明人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
IPC分类号： C07K14/34 , C12N1/21 , C12P13/08
CPC分类号： C12P13/08 , C07K14/34
摘要： The present invention relates to polynucleotides corresponding to the lysR1 gene and which encode a LysR1 transcriptional regulator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LysR1 transcriptional regulator activity.
摘要翻译：本发明涉及对应于lysR1基因并编码LysR1转录调节剂的多核苷酸，产生L-氨基酸的方法，以及筛选编码具有LysR1转录调节活性的蛋白质的多核苷酸的方法。

8. 发明申请

US20050089976A1 Nucleotide sequences coding for the lysRI gene 审中-公开
标题翻译：编码lysRI基因的核苷酸序列
公开(公告)号：US20050089976A1
公开(公告)日：2005-04-28
申请号：US10872565
申请日：2004-06-22
申请人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
发明人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
IPC分类号： C07K14/34 , C12N1/21 , C12P13/08 , C12P21/04
CPC分类号： C12P13/08 , C07K14/34
摘要： The present invention relates to polynucleotides corresponding to the lysR1 gene and which encode a LysR1 transcriptional regulator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LysR3 transcriptional regulator activity.
摘要翻译：本发明涉及对应于lysR1基因并编码LysR1转录调节子的多核苷酸，产生L-氨基酸的方法，以及筛选编码具有LysR3转录调节活性的蛋白质的多核苷酸的方法。

9. 发明授权

US07078502B2 Nucleotide sequences for encoding of the lysR2-gene 失效
标题翻译：编码lysR2基因的核苷酸序列
公开(公告)号：US07078502B2
公开(公告)日：2006-07-18
申请号：US09826909
申请日：2001-04-06
申请人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
发明人： Bettina Moeckel , Mike Farwick , Thomas Hermann , Caroline Kreutzer , Walter Pfefferle
IPC分类号： C07H21/02 , C07H21/04 , C12N15/00 , C12N15/09 , C12N15/63
CPC分类号： C12P13/08 , C07K14/34
摘要： Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the lysR2 gene is present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.
摘要翻译：分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同的多核苷酸，b）多核苷酸，其编码多肽，其包含与SEQ ID No.2的氨基酸序列至少70％的程度相同的氨基酸序列，c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少lysR2基因存在于减毒形式，以及使用多核苷酸序列作为杂交探针。

10. 发明授权

US06783967B2 Nucleotide sequences which code for the rpoB gene 失效
标题翻译：编码rpoB基因的核苷酸序列
公开(公告)号：US06783967B2
公开(公告)日：2004-08-31
申请号：US09887052
申请日：2001-06-25
申请人： Bettina Moeckel , Brigitte Bathe , Thomas Hermann , Walter Pfefferle , Michael Binder
发明人： Bettina Moeckel , Brigitte Bathe , Thomas Hermann , Walter Pfefferle , Michael Binder
IPC分类号： C12N912
CPC分类号： C07K14/34 , C12P13/08
摘要： The present invention relates to polynucleotides corresponding to the rpoB gene and which encode the &bgr;-subunit of RNA polymerase B, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having activity of the &bgr;-subunit of RNA polymerase B.
摘要翻译：本发明涉及对应于rpoB基因并编码RNA聚合酶B的β-亚单位的多核苷酸，产生L-氨基酸的方法，以及筛选编码具有RNA聚合酶的β-亚基活性的蛋白质的多核苷酸的方法 B.

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