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1. 发明申请

US20070290145A1 System and Method for Carrying Out Fibre-Type Multiphoton Microscopic Imaging of a Sample 有权
标题翻译：用于进行样品的光纤型多光子显微镜成像的系统和方法
公开(公告)号：US20070290145A1
公开(公告)日：2007-12-20
申请号：US11665768
申请日：2005-10-21
申请人： Bertrand Viellerobe , Francois Lacombe , Alexandre Loiseau , Frederic Louradour , Mikael Lelek , Alain Barthelemy , Domoinique Pagnoux
发明人： Bertrand Viellerobe , Francois Lacombe , Alexandre Loiseau , Frederic Louradour , Mikael Lelek , Alain Barthelemy , Domoinique Pagnoux
IPC分类号： G21K5/04 , F21K2/00 , F21V9/16
CPC分类号： G02B23/2484 , A61B5/0062 , A61B5/0068 , A61B5/0071 , A61B5/0075 , A61B5/0086 , G01N21/6452 , G01N21/6458 , G01N2021/6417 , G01N2021/6484 , G01N2201/08 , G01N2201/1053 , G02B6/04 , G02B21/002 , G02B21/16 , G02B23/2469
摘要： A system for carrying out fibered multiphoton microscopic imagery of a sample (10) for use in endoscopy or fluorescence microscopy includes: a femtosecond pulsed laser (1, 2) for generating a multiphoton excitation laser radiation; an image guide (8) having a number of optical fibers and permitting the sample to be illuminated by a point-by-point scanning in a subsurface plane; pre-compensating elements (4) for pre-compensating for dispersion effects of the excitation pulses in the image guide (8), these elements being situated between the pulsed laser and the image guide (8); scanning elements for directing, in succession, the excitation laser beam in a fiber of the image guide, and; in particular, an optical head (9) for focussing the excitation laser beam exiting the image guide in the sample (10).
摘要翻译：用于进行用于内窥镜检查或荧光显微镜检查的样品（10）的纤维多光子显微镜图像的系统包括：用于产生多光子激发激光辐射的飞秒脉冲激光器（1,2）具有多个光纤的图像引导件（8），并允许通过在地下平面中的逐点扫描照亮样品; 预补偿元件（4），用于对图像引导件（8）中的激励脉冲的色散效应进行预补偿，这些元件位于脉冲激光器和图像引导件（8）之间; 用于连续地引导图像引导件的光纤中的激发激光束的扫描元件，以及特别地，用于聚焦离开图像引导件的激发激光束在样品（10）中的光学头（9）。

2. 发明授权

US08237131B2 System and method for carrying out fibre-type multiphoton microscopic imaging of a sample 有权
标题翻译：用于进行样品的纤维型多光子显微镜成像的系统和方法
公开(公告)号：US08237131B2
公开(公告)日：2012-08-07
申请号：US11665768
申请日：2005-10-21
申请人： Bertrand Viellerobe , Francois Lacombe , Alexandre Loiseau , Frederic Louradour , Mickael Lelek , Alain Barthelemy , Dominique Pagnoux
发明人： Bertrand Viellerobe , Francois Lacombe , Alexandre Loiseau , Frederic Louradour , Mickael Lelek , Alain Barthelemy , Dominique Pagnoux
IPC分类号： G21K5/04
CPC分类号： G02B23/2484 , A61B5/0062 , A61B5/0068 , A61B5/0071 , A61B5/0075 , A61B5/0086 , G01N21/6452 , G01N21/6458 , G01N2021/6417 , G01N2021/6484 , G01N2201/08 , G01N2201/1053 , G02B6/04 , G02B21/002 , G02B21/16 , G02B23/2469
摘要： A system for carrying out fibered multiphoton microscopic imagery of a sample (10) for use in endoscopy or fluorescence microscopy includes: a femtosecond pulsed laser (1, 2) for generating a multiphoton excitation laser radiation; an image guide (8) having a number of optical fibers and permitting the sample to be illuminated by a point-by-point scanning in a subsurface plane; pre-compensating elements (4) for pre-compensating for dispersion effects of the excitation pulses in the image guide (8), these elements being situated between the pulsed laser and the image guide (8); scanning elements for directing, in succession, the excitation laser beam in a fiber of the image guide, and; in particular, an optical head (9) for focussing the excitation laser beam exiting the image guide in the sample (10).
摘要翻译：用于进行用于内窥镜检查或荧光显微镜的样品（10）的纤维多光子显微镜图像的系统包括：用于产生多光子激发激光辐射的飞秒脉冲激光器（1,2）具有多个光纤的图像引导件（8），并允许通过在地下平面中的逐点扫描照亮样品; 预补偿元件（4），用于对图像引导件（8）中的激励脉冲的色散效应进行预补偿，这些元件位于脉冲激光器和图像引导件（8）之间; 用于连续地引导图像引导件的光纤中的激发激光束的扫描元件，以及特别地，用于聚焦离开图像引导件的激发激光束在样品（10）中的光学头（9）。

3. 发明授权

US10191343B2 Device and process for forming laser pulses 有权
公开(公告)号：US10191343B2
公开(公告)日：2019-01-29
申请号：US13510232
申请日：2010-11-16
申请人： Frederic Louradour , Vincent Kermene , Alain Barthelemy , Eric Suran , Tigran Mansuryan
发明人： Frederic Louradour , Vincent Kermene , Alain Barthelemy , Eric Suran , Tigran Mansuryan
IPC分类号： G02B26/00 , G02F1/01 , G02F1/1362 , H01S3/00
摘要： The invention relates to a device for forming laser pulses comprising: an input for a pulsed laser beam; a spatial phase modulator (300), arranged on the trajectory of said pulsed laser beam so as to be illuminated thereby; a control means designed to configure said spatial phase modulator so as to emulate a diffraction grating (3, 3′) having a diffraction efficiency that varies along one spatial direction (s) identified by the intersection of the modulator surface with the diffraction plane (xz); and spatial filtering means (5) for a light beam diffracted by said grating; whereby a laser pulse (P1) at the device input is converted to a train of elementary output pulses (PS) having temporal intensity and/or phase and/or polarization modulation. The invention further relates to a laser pulse forming process based on the use of such a device.

4. 发明授权

US08913645B2 Laser cavity with central extraction by polarisation for coherent coupling of intense intra-cavity beams 有权
标题翻译：激光腔具有通过极化的中心提取，用于强烈腔内光束的相干耦合
公开(公告)号：US08913645B2
公开(公告)日：2014-12-16
申请号：US13696259
申请日：2011-05-04
申请人： David Sabourdy , Jean-Eucher Montagne , Alain Barthelemy , Agnes Desfarges-Berthelemot , Vincent Kermene , Sandrine Auroux , Julien Guillot , Brigitte Serreault , Bruno Esmiller
发明人： David Sabourdy , Jean-Eucher Montagne , Alain Barthelemy , Agnes Desfarges-Berthelemot , Vincent Kermene , Sandrine Auroux , Julien Guillot , Brigitte Serreault , Bruno Esmiller
IPC分类号： H01S3/08 , H01S3/07 , H01S3/05 , H01S3/23 , H01S3/11 , H01S3/10 , H01S3/082
CPC分类号： H01S3/05 , H01S3/07 , H01S3/08 , H01S3/082 , H01S3/10053 , H01S3/11 , H01S3/2383
摘要： The invention relates to a laser cavity with central extraction by polarisation for coherent coupling of intense intra-cavity beams. The laser cavity (1) according to the invention comprises an extraction unit (7) with central extraction, which divides the laser cavity (1) longitudinally into two functional portions (P1, P2), namely a first portion (P1) including the active components (3), which amplifies the laser beams (4), and a second portion (P2) which performs coherent coupling of the laser beams (4).
摘要翻译：本发明涉及一种具有通过极化中心提取的激光腔，用于强烈腔内光束的相干耦合。根据本发明的激光腔（1）包括具有中心提取的提取单元（7），其将激光腔（1）纵向分成两个功能部分（P1，P2），即包括活动的第一部分放大激光束（4）的部件（3）和执行激光束（4）的相干耦合的第二部分（P2）。

5. 发明申请

US20100158054A1 LASER SYSTEM WITH PICOSECOND PULSE EMISSION 有权
标题翻译：具有PICOSECOND脉冲发射的激光系统
公开(公告)号：US20100158054A1
公开(公告)日：2010-06-24
申请号：US12515839
申请日：2007-11-21
申请人： Paul-Henri Pioger , Bertrand Vergne , Vincent Couderc , Alain Barthelemy
发明人： Paul-Henri Pioger , Bertrand Vergne , Vincent Couderc , Alain Barthelemy
IPC分类号： H01S3/11 , H01S3/10
CPC分类号： H01S3/067 , G02F1/3511 , H01S3/06712 , H01S3/08031 , H01S3/094076 , H01S3/1112
摘要： The invention relates to a device (1) for generating short pulses, said device being characterised in that it comprises: a polarised pulse laser (10, 2, 3) having a polarisation direction; a bi-refringent optical fibre (6) having bi-refringence axes, wherein said polarisation direction is not co-linear with said bi-refringence axes; an output polariser (9) provided at the output of said fibre, said polariser being capable of selecting a polarisation at the output of said fibre; wherein said pulse laser in a longitudinally quasi-single mode laser.
摘要翻译：本发明涉及一种用于产生短脉冲的装置（1），所述装置的特征在于它包括：具有偏振方向的偏振脉冲激光器（10,2,3）具有双折射轴的双折射光纤（6），其中所述偏振方向与所述双折射轴线不是共线的; 设置在所述光纤的输出处的输出偏振器（9），所述偏振器能够在所述光纤的输出处选择极化; 其中所述脉冲激光器在纵准准单模激光器中。

6. 发明授权

US08665436B2 Device and method for determining a piece of polarisation information and polarimetric imaging device 有权
标题翻译：用于确定偏振信息和偏振成像装置的装置和方法
公开(公告)号：US08665436B2
公开(公告)日：2014-03-04
申请号：US13144311
申请日：2010-01-15
申请人： Dominique Pagnoux , Frédéric Louradour , Jérôme Desroches , Alain Barthelemy , Julien Brevier
发明人： Dominique Pagnoux , Frédéric Louradour , Jérôme Desroches , Alain Barthelemy , Julien Brevier
IPC分类号： G01J4/00
CPC分类号： G01J4/04 , A61B5/0059 , A61B5/0062 , A61B5/0064 , A61B5/442 , G01N21/21 , G01N2021/8438
摘要： The invention relates to a method and to a device for determining a piece of polarisation information on a measurement point of a target sample, the device comprising: —a light source capable of emitting a rectilinearly polarised light beam in a predefined direction, the light beam being intended to be reflected by the measurement point of the target sample; —a unit for computing the piece of polarisation information on the measurement point using the beam reflected by the target sample; -a waveguide for guiding the incident beam towards the target sample and the reflected beam towards the computing means; and —a unit for rotating the polarisation, capable of rotating two orthogonal polarimetric components of the incident beam exiting the waveguide and two orthogonal polarimetric components of the reflected beam before passing through the waveguide.
摘要翻译：本发明涉及一种用于在目标样本的测量点上确定一段偏振信息的方法和装置，该装置包括： - 能够沿预定方向发射直线偏振光束的光源，光束旨在由目标样本的测量点反映; - 用于使用由目标样本反射的光束计算测量点上的偏振信息的单元; - 用于将入射光束引向目标样本的波导和朝向计算装置的反射光束; 以及 - 用于旋转偏振的单元，能够在穿过波导之前旋转离开波导的入射光束的两个正交偏振分量和反射光束的两个正交偏振分量。

7. 发明申请

US20130188244A1 METHOD AND DEVICE FOR AMPLIFYING AN OPTICAL SIGNAL 有权
标题翻译：用于放大光信号的方法和装置
公开(公告)号：US20130188244A1
公开(公告)日：2013-07-25
申请号：US13819818
申请日：2011-09-05
申请人： Vincent Kermene , Agnès Desfarges-Berthelemot , Alain Barthelemy
发明人： Vincent Kermene , Agnès Desfarges-Berthelemot , Alain Barthelemy
IPC分类号： H01S3/067
CPC分类号： H01S3/06725 , H01S3/0057 , H01S3/0675
摘要： According to the invention, the optical signal (SE) is spatially divided into N elementary optical signals (SE.1, SE.2, . . . , SE.N), the spectral ranges thereof being adjacent in pairs and forming, substantially by juxtaposition, the spectral range of the optical signal; these N elementary signals are amplified respectively by means of N elementary amplifiers (4.1, 4.2, . . . , 4.N), the spectral ranges thereof respectively comprising the spectral ranges of said N elementary signals; the N amplified elementary signals (Ss.1, Ss.2, . . . , Ss.N) are assembled to form an amplified optical signal (Ss), the spectral range thereof substantially coinciding with a predetermined spectral range, and finally the spectral phases of the N initial elementary signals (Ss.1, Ss.2, . . . , Ss.N) are adjusted before amplification on the basis of the spectral phase of said amplified signal (Ss).
摘要翻译：根据本发明，光信号（SE）在空间上划分为N个基本光信号（SE.1，SE.2，...，SE.N），其光谱范围成对相邻并基本上由并置，光信号的光谱范围; 这些N个基本信号分别通过N个基本放大器（4.1,4.2，...，4.N）进行放大，其光谱范围分别包括所述N个基本信号的光谱范围; 组合N个放大的基本信号（Ss.1，Ss.2，...，Ss.N）以形成放大的光信号（Ss），其光谱范围基本上与预定的光谱范围一致，最后是光谱根据所述放大信号（Ss）的频谱相位，在放大前调整N个初始基本信号（Ss.1，Ss.2，...，Ss.N）的相位。

8. 发明申请

US20120262772A1 Device and Process for Forming Laser Pulses 审中-公开
标题翻译：用于形成激光脉冲的装置和工艺
公开(公告)号：US20120262772A1
公开(公告)日：2012-10-18
申请号：US13510232
申请日：2010-11-16
申请人： Frédéric Louradour , Vincent Kermene , Alain Barthelemy , Eric Suran , Tigran Mansuryan
发明人： Frédéric Louradour , Vincent Kermene , Alain Barthelemy , Eric Suran , Tigran Mansuryan
IPC分类号： G02B26/06
CPC分类号： G02F1/136277 , G02F2203/12 , G02F2203/26 , G02F2203/50 , H01S3/0057
摘要： The invention relates to a device for forming laser pulses comprising: an input for a pulsed laser beam; a spatial phase modulator (300), arranged on the trajectory of said pulsed laser beam so as to be illuminated thereby; a control means designed to configure said spatial phase modulator so as to emulate a diffraction grating (3, 3′) having a diffraction efficiency that varies along one spatial direction (s) identified by the intersection of the modulator surface with the diffraction plane (xz); and spatial filtering means (5) for a light beam diffracted by said grating; whereby a laser pulse (P1) at the device input is converted to a train of elementary output pulses (PS) having temporal intensity and/or phase and/or polarization modulation. The invention further relates to a laser pulse forming process based on the use of such a device.
摘要翻译：本发明涉及一种用于形成激光脉冲的装置，包括：用于脉冲激光束的输入; 空间相位调制器（300），布置在所述脉冲激光束的轨迹上以被照明; 一种控制装置，被设计成配置所述空间相位调制器以仿真具有衍射效率的衍射光栅（3,3'），该衍射光栅沿着由调制器表面与衍射平面相交的一个空间方向（xz ）; 和用于由所述光栅衍射的光束的空间滤波装置（5）; 由此将器件输入处的激光脉冲（P1）转换成具有时间强度和/或相位和/或偏振调制的基本输出脉冲串（PS）。本发明还涉及基于这种装置的使用的激光脉冲形成过程。

9. 发明授权

US4928282A Laser generator with phase mode-locking 失效
标题翻译：激光发生器具有相位锁定功能
公开(公告)号：US4928282A
公开(公告)日：1990-05-22
申请号：US276448
申请日：1988-10-20
申请人： Alain Barthelemy , Serge Maneuf , Claude Froehly
发明人： Alain Barthelemy , Serge Maneuf , Claude Froehly
IPC分类号： H01S3/098 , H01S5/00
CPC分类号： H01S3/1112 , H01S2301/085 , H01S3/0805 , H01S3/08054 , H01S3/08059
摘要： The laser generator includes a device for phase-locking the mode of the laser generator, the device being placed between the amplifying active medium (3) and the rear reflecting mirror (1) and comprising, firstly a non-dispersive non-linear medium (5) placed in contact with said rear mirror (1), and secondly means (11 to 16) for transforming a Gaussian beam having circular symmetry coming from the amplifying medium into a beam whose morphology is adapted to soliton propagation in said non-linear medium (5). The invention avoids the use of acousto-optical type modulators and may be applied to a very wide range of wavelengths.
摘要翻译： PCT No. OCT / FR88 / 00100 Sec。 371日期：1988年10月20日 102（e）日期1988年10月20日PCT提交1988年2月23日PCT公布。出版物WO88 / 06811 日期：1988年9月7日。激光发生器包括用于相位锁定激光发生器的模式的装置，该装置被放置在放大有源介质（3）和后反射镜（1）之间，并且包括： - 分散非线性介质（5），其与所述后反射镜（1）接触，其次用于将具有来自放大介质的具有圆形对称性的高斯束变换成其形态适用于孤子的光束的装置（11至16）在所述非线性介质（5）中的传播。本发明避免使用声光型调制器并且可以应用于非常宽的波长范围。

10. 发明授权

US08908262B2 Method and device for amplifying an optical signal 有权
标题翻译：用于放大光信号的方法和装置
公开(公告)号：US08908262B2
公开(公告)日：2014-12-09
申请号：US13819818
申请日：2011-09-05
申请人： Vincent Kermene , Agnès Desfarges-Berthelemot , Alain Barthelemy
发明人： Vincent Kermene , Agnès Desfarges-Berthelemot , Alain Barthelemy
IPC分类号： H01S3/23
CPC分类号： H01S3/06725 , H01S3/0057 , H01S3/0675
摘要： According to the invention, the optical signal (SE) is spatially divided into N elementary optical signals (SE.1, SE.2, . . . , SE.N), the spectral ranges thereof being adjacent in pairs and forming, substantially by juxtaposition, the spectral range of the optical signal; these N elementary signals are amplified respectively by means of N elementary amplifiers (4.1, 4.2, . . . , 4.N), the spectral ranges thereof respectively comprising the spectral ranges of said N elementary signals; the N amplified elementary signals (Ss.1, Ss.2, . . . , Ss.N) are assembled to form an amplified optical signal (Ss), the spectral range thereof substantially coinciding with a predetermined spectral range, and finally the spectral phases of the N initial elementary signals (Ss.1, Ss.2, . . . , Ss.N) are adjusted before amplification on the basis of the spectral phase of said amplified signal (Ss).
摘要翻译：根据本发明，光信号（SE）在空间上划分为N个基本光信号（SE.1，SE.2，...，SE.N），其光谱范围成对相邻并基本上由并置，光信号的光谱范围; 这些N个基本信号分别通过N个基本放大器（4.1,4.2，...，4.N）进行放大，其光谱范围分别包括所述N个基本信号的光谱范围; 组合N个放大的基本信号（Ss.1，Ss.2，...，Ss.N）以形成放大的光信号（Ss），其光谱范围基本上与预定的光谱范围一致，最后是光谱根据所述放大信号（Ss）的频谱相位，在放大前调整N个初始基本信号（Ss.1，Ss.2，...，Ss.N）的相位。

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