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1. 发明授权

US10765412B2 Endoscopic instrument with support foot 有权
公开(公告)号：US10765412B2
公开(公告)日：2020-09-08
申请号：US14123659
申请日：2012-06-25
申请人： Benoît Rosa , Benoît Herman , Jérôme Szewczyk , Guillaume Morel , Clément Vidal , Patrick Henri , François Lacombe , Jérôme Lopez
发明人： Benoît Rosa , Benoît Herman , Jérôme Szewczyk , Guillaume Morel , Clément Vidal , Patrick Henri , François Lacombe , Jérôme Lopez
IPC分类号： A61B1/00 , A61B17/00 , A61B34/00
摘要： The invention relates to an endoscopic instrument (1) having an elongate body with a distal end (4) designed to be introduced into the body of the patient so as to come into proximity with an internal organ, the distal end carrying a tool (7) for intervention on the internal organ. The endoscopic instrument has a fool (10) rigidly connected to the distal end and designed to bear on the internal organ, and also controllable means (13) for conferring movements on the tool, at least in directions transverse to a longitudinal axis (X) of the distal end of the endoscopic instrument, when the foot is bearing against the internal organ.

2. 发明申请

US20140207150A1 ENDOSCOPIC INSTRUMENT WITH SUPPORT FOOT 审中-公开
标题翻译：带支撑脚的内窥镜仪器
公开(公告)号：US20140207150A1
公开(公告)日：2014-07-24
申请号：US14123659
申请日：2012-06-25
申请人： Benoît Rosa , Benoît Herman , Jérôme Szewczyk , Guillaume Morel , Clément Vidal , Patrick Henri , François Lacombe , Jérôme Lopez
发明人： Benoît Rosa , Benoît Herman , Jérôme Szewczyk , Guillaume Morel , Clément Vidal , Patrick Henri , François Lacombe , Jérôme Lopez
IPC分类号： A61B17/00 , A61B19/00
摘要： The invention relates to an endoscopic instrument (1) having an elongate body with a distal end (4) designed to be introduced into the body of the patient so as to come into proximity with an internal organ, the distal end carrying a tool (7) for intervention on the internal organ. The endoscopic instrument has a fool (10) rigidly connected to the distal end and designed to bear on the internal organ, and also controllable means (13) for conferring movements on the tool, at least in directions transverse to a longitudinal axis (X) of the distal end of the endoscopic instrument, when the foot is bearing against the internal organ.
摘要翻译：本发明涉及一种内窥镜器械（1），其具有细长体，其具有设计成被引入患者体内的远端（4），以便与内部器官接近，远端承载工具（7 ）干预内脏。内窥镜仪器具有刚性地连接到远端并被设计成承载在内部器官上的傻瓜（10），以及用于赋予工具上的运动的可控制装置（13），至少在横向于纵向轴线（X）的方向上，的内窥镜仪器的远端，当脚抵靠内脏器官时。

3. 发明授权

US07950801B2 Device and method for measuring the contrast of the fringes in a michelson interferometer and system for examination of the eye comprising such a device 有权
标题翻译：用于测量迈克尔逊干涉仪中的边缘的对比度的装置和方法以及用于眼睛检查的系统，包括这种装置
公开(公告)号：US07950801B2
公开(公告)日：2011-05-31
申请号：US10586897
申请日：2005-01-21
申请人： François Lacombe , David Lafaille
发明人： François Lacombe , David Lafaille
IPC分类号： A61B3/10 , A61B3/14
CPC分类号： G01B9/02063 , A61B3/1225 , G01B9/02014 , G01B9/02068 , G01B9/02069 , G01B9/02077 , G01B9/02081 , G01B9/02091 , G01B2290/70
摘要： The invention relates to a device, for measuring the contrast of fringes in a Michelson interferometer at full field, comprising a Wollaston prism for diverting two perpendicular incident polarizations into two different emergent directions, said diverting means being arranged within the interferometer as substitute for a single polarizer. The device is of application to a Michelson interferometer used in an OCT tomographical system and comprising means for obtaining interferometric contrast without use of a modulation technique or synchronous detection methods.
摘要翻译：本发明涉及一种用于测量迈克尔逊干涉仪在全场的条纹的对比度的装置，包括用于将两个垂直入射偏振转向两个不同的出射方向的沃拉斯顿棱镜，所述转向装置布置在干涉仪内作为单个偏光片。该装置适用于在OCT层析系统中使用的迈克尔逊干涉仪，并且包括用于在不使用调制技术或同步检测方法的情况下获得干涉式对比度的装置。

4. 发明授权

US07658495B2 Eye examination device by means of tomography with a sighting device 有权
标题翻译：眼科检查装置通过用瞄准装置进行断层扫描
公开(公告)号：US07658495B2
公开(公告)日：2010-02-09
申请号：US12210058
申请日：2008-09-12
申请人： François Lacombe , David Lafaille , Marie Glanc , Eric Gendron , Douchane Stefanovitch
发明人： François Lacombe , David Lafaille , Marie Glanc , Eric Gendron , Douchane Stefanovitch
IPC分类号： A61B3/10 , A61B3/14 , A61B3/00
CPC分类号： A61B3/0091
摘要： A sighting device for an examination by in vivo tomography of an eye of a subject including a viewer controlled by a control system for displaying at least one moving target where the at least one moving target has at least one of a programmable shape and a programmable trajectory, and is visible by the eye of the subject during the examination period to allow the subject to fixate and follow the target with their eye.
摘要翻译：一种用于通过体内层析成像进行检查的瞄准装置，包括由控制系统控制的观察者，用于显示至少一个移动目标的至少一个移动目标，其中所述至少一个移动目标具有可编程形状和可编程轨迹中的至少一个并且在检查期间由受试者的眼睛可见，以允许受试者用眼睛固定和跟踪目标。

5. 发明授权

US07336990B2 Equipment for subsurface autofluorescence spectroscopy 有权
标题翻译：地下自发荧光光谱仪
公开(公告)号：US07336990B2
公开(公告)日：2008-02-26
申请号：US10500162
申请日：2002-12-20
申请人： Magalie Genet , Geneviève Bourg-Heckly , Sandrine Vilette , François Lacombe , Alexandre Loiseau , Benjamin Abrat
发明人： Magalie Genet , Geneviève Bourg-Heckly , Sandrine Vilette , François Lacombe , Alexandre Loiseau , Benjamin Abrat
IPC分类号： A61B6/00
CPC分类号： G01N21/6486 , A61B5/0068 , A61B5/0071 , A61B5/0075 , A61B5/0084 , G01N21/6456
摘要： An equipment includes an excitation source (1), elements for injecting (2) an excitation signal produced by the source in an ordered bundle (3) of flexible optical fibers, elements for analyzing (21, 22) an emitted autofluorescence signal. The equipment also includes at the output of the optical fiber bundle (3) an optical head (4) designed to be placed in contact with the biological tissue (6), the optical head being equipped with optical elements adapted to cause the excitation signal output from the bundle (3) to converge into a subsurface analyzing zone (5), the same optical fiber(s) used for excitation of the bundle (3) being used for detecting the signal emitted by the subsurface analyzing zone, elements (D) placed upstream of the injection elements (2) being further provided to separate the wavelength of the excitation signal and the wavelength of the autofluorescence signal.
摘要翻译：一种设备包括激励源（1），用于注入（2）由柔性光纤的有序束（3）中的源产生的激励信号的元件，用于分析（21,22）发射的自发荧光信号的元件。所述设备还包括在所述光纤束（3）的输出端处设计成与所述生物组织（6）接触的光学头（4），所述光学头装备有适于使所述激发信号输出从束（3）收敛到地下分析区（5）中，用于激发束（3）的相同光纤用于检测由地下分析区发出的信号，元件（D）放置在注入元件（2）的上游的进一步提供以分离激发信号的波长和自发荧光信号的波长。

6. 发明授权

US07285089B2 Confocal imaging equipment in particular for endoscope 有权
标题翻译：共焦成像设备，特别是内窥镜
公开(公告)号：US07285089B2
公开(公告)日：2007-10-23
申请号：US10500160
申请日：2002-12-20
申请人： Bertrand Viellerobe , Magalie Genet , Frédéric Berier , François Lacombe , Aymeric Perchant , Georges Le Goualher , Sandra Marti , Stéphane Bourriaux
发明人： Bertrand Viellerobe , Magalie Genet , Frédéric Berier , François Lacombe , Aymeric Perchant , Georges Le Goualher , Sandra Marti , Stéphane Bourriaux
IPC分类号： A61B1/06 , G02B26/08
CPC分类号： A61B1/00188 , A61B1/00165 , A61B1/042 , A61B1/07 , A61B2562/0242 , G02B23/2469
摘要： Equipment includes an image guide (1) consisting of flexible optical fibers with: on the proximal end side: a source (2), angular scanning elements (3), injection elements (4) in one of the fibers, elements for splitting (5) the illuminating beam and the backscattered signal, elements for spatial filtering (6), elements for detecting (7) the signal, electronic elements (8) for controlling, analyzing and digital processing of the detected signal and display; and on the distal end side: an optical head (9) for focusing the illuminating beam exiting from the illuminated fiber. The scanning elements include a resonant line mirror (M1) and a galvanometric field mirror (M2) with a variable frequency and two afocal optical systems adapted to conjugate the two mirrors (M1, M2) firstly in the field mirror (M2) and the injection elements (4) in the image guide in a second step.
摘要翻译：设备包括由柔性光纤组成的图像引导件（1），其具有：在基端侧：源（2），角扫描元件（3），其中一个光纤中的注入元件（4），用于分离的元件（5 ）照明光束和反向散射信号，用于空间滤波的元件（6），用于检测信号的元件（7），用于控制，分析和数字处理检测信号和显示的电子元件（8）; 并且在远端侧：用于聚焦从照明光纤出射的照明光束的光学头（9）。扫描元件包括谐振线路反射镜（M1）和具有可变频率的电流计镜（M 2）和适于首先在场反射镜（M 2）和图像引导件中的注入元件（4）。

7. 发明授权

US07513619B2 High resolution laterial and axial tomography 有权
标题翻译：高分辨率材料和轴向断层扫描
公开(公告)号：US07513619B2
公开(公告)日：2009-04-07
申请号：US10586716
申请日：2005-01-21
申请人： François Lacombe , David Lafaille , Marie Glanc , Eric Gendron
发明人： François Lacombe , David Lafaille , Marie Glanc , Eric Gendron
IPC分类号： A61B3/10 , G01B11/02
CPC分类号： A61B3/102
摘要： An in-vivo high resolution lateral and axial tomography system of the retina, is provided, including a Michelson interferometer, generating a tomographical image by full field OCT interference with Z sweeping, adaptive optical correction apparatus, correcting the wave fronts coming from and going to the eye, including a reference source, a deformable mirror and wave surface analysis apparatus, detection apparatus producing an image from an interferometric measurement using the OCT principle and apparatus for focussing the wave surface analyser. The apparatus for focussing are embodied and controlled, synchronously with the Z sweeping to force the deformable mirror to adopt an additional curvature, such as to combine the input light source and detection apparatus at a given depth in the retina.
摘要翻译：提供视网膜的体内高分辨率横向和轴向断层摄影系统，包括迈克尔逊干涉仪，通过全场OCT干涉Z扫描产生断层图像，自适应光学校正装置，校正来自和进入的波前眼睛，包括参考源，可变形反射镜和波面分析装置，使用OCT原理从干涉测量产生图像的检测装置和用于聚焦波面分析仪的装置。用于聚焦的装置被实施和控制，与Z扫描同步，以迫使可变形反射镜采用额外的曲率，例如将输入光源和检测装置组合在视网膜中给定的深度处。

8. 发明授权

US07438415B2 Eye examination device by means of tomography with a sighting device 有权
标题翻译：眼科检查装置通过用瞄准装置进行断层扫描
公开(公告)号：US07438415B2
公开(公告)日：2008-10-21
申请号：US10586839
申请日：2005-01-21
申请人： François Lacombe , David Lafaille , Marie Glanc , Eric Gendron , Douchane Stefanovitch
发明人： François Lacombe , David Lafaille , Marie Glanc , Eric Gendron , Douchane Stefanovitch
IPC分类号： A61B3/10 , A61B3/14 , A61B3/00
CPC分类号： A61B3/0091
摘要： A sighting device is provided for an examination of the eye, including at least one moving target with a programmable form and trajectory, the target being displayed on a visualisation unit, such as an appropriate screen and visible from both eyes during the examination. An in-vivo tomographical eye examination system is also provided, including: a Michelson interferometer, generating a full-field OCT image, adaptable optical apparatus, arranged between the interferometer and an eye for examination, achieving the correction of the wavefronts coming from the eye and also the wavefronts going to the eye, detection apparatus, arranged after the interferometer, permitting the interferometric measurement by the OCT principle without modulation nor synchronized detection and a sighting device, with at least one mobile target with a programmable form and trajectory, the target being displayed on an appropriate screen and visible from at least one of the eyes during the examination.
摘要翻译：提供了一种用于检查眼睛的瞄准装置，包括至少一个具有可编程形式和轨迹的移动目标，目标被显示在可视化单元（例如适当的屏幕上）并且在检查期间从双眼可见。还提供了一种体内断层扫描检查系统，包括：迈克尔逊干涉仪，生成全场OCT图像，适应光学装置，布置在干涉仪和眼睛之间进行检查，实现来自眼睛的波前的校正以及布置在干涉仪之后的波前，检测装置，允许通过OCT原理进行干涉测量而不进行调制或同步检测，以及具有可编程形式和轨迹的至少一个移动目标的瞄准装置，目标在检查期间显示在适当的屏幕上并且从至少一个眼睛可见。

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