专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07394642B2 Tubular capacitor with variable capacitance and dielectrically elongated inner electrode for NMR applications 有权
标题翻译：具有可变电容的管状电容器和用于NMR应用的介电延长的内部电极
公开(公告)号：US07394642B2
公开(公告)日：2008-07-01
申请号：US11509781
申请日：2006-08-25
申请人： Beat Grossniklaus , Daniel Marek , Roberto Seydoux , Oskar Schett
发明人： Beat Grossniklaus , Daniel Marek , Roberto Seydoux , Oskar Schett
IPC分类号： H01G5/04 , H01G4/06
CPC分类号： G01R33/3628 , H01G5/014 , H01G5/14
摘要： A tubular capacitor with variable capacitance, including a cylindrical tube (3) of dielectric material, a metallic outer electrode (1) which surrounds the cylindrical tube (3), and an inner electrode which can axially move in the inner bore (41) of the cylindrical tube (3) and which abuts the inner bore (41), wherein the inner electrode includes a metallic rod (2; 2a; 2b; 2c), is characterized in that the metallic rod (2; 2a; 2b; 2c) is axially extended at its end (5′), located in the inner bore (41) of the cylindrical tube (3), using a rod (9; 9a; 9b; 9c) of dielectric material. The inventive tubular capacitor has an increased dielectric strength and improves the resolution of NMR spectrometers.
摘要翻译：一种具有可变电容的管状电容器，包括介电材料的圆柱形管（3），围绕圆柱形管（3）的金属外电极（1）和可在内孔（41）中轴向移动的内电极所述圆柱形管（3）邻接所述内孔（41），其中所述内部电极包括金属杆（2; 2a; 2b; 2c），其特征在于，所述金属杆（2; 2b; 2c）在其端部（5'）处轴向延伸，位于圆柱形管（3）的内孔（41）中，使用电介质的棒（9; 9a; 9c; 9c）材料。本发明的管状电容器具有增加的介电强度并提高NMR光谱仪的分辨率。

2. 发明申请

US20070070578A1 Tubular capacitor with variable capacitance and dielectrically elongated inner electrode for NMR applications 有权
标题翻译：具有可变电容的管状电容器和用于NMR应用的介电延长的内部电极
公开(公告)号：US20070070578A1
公开(公告)日：2007-03-29
申请号：US11509781
申请日：2006-08-25
申请人： Beat Grossniklaus , Daniel Marek , Roberto Seydoux , Oskar Schett
发明人： Beat Grossniklaus , Daniel Marek , Roberto Seydoux , Oskar Schett
IPC分类号： H01G4/28
CPC分类号： G01R33/3628 , H01G5/014 , H01G5/14
摘要： A tubular capacitor with variable capacitance, comprising a cylindrical tube (3) of dielectric material, a metallic outer electrode (1) which surrounds the cylindrical tube (3), and an inner electrode which can axially move in the inner bore (41) of the cylindrical tube (3) and which abuts the inner bore (41), wherein the inner electrode comprises a metallic rod (2; 2a; 2b; 2c), is characterized in that the metallic rod (2; 2a; 2b; 2c) is axially extended at its end (5′), located in the inner bore (41) of the cylindrical tube (3), using a rod (9; 9a; 9b; 9c) of dielectric material. The inventive tubular capacitor has an increased dielectric strength and improves the resolution of NMR spectrometers.
摘要翻译：一种具有可变电容的管状电容器，包括介电材料的圆柱形管（3），围绕所述圆柱形管（3）的金属外电极（1）和能够在所述内孔（41）中轴向移动的内电极所述圆柱形管（3）邻接所述内孔（41），其中所述内部电极包括金属杆（2; 2a; 2b; 2c），其特征在于，所述金属杆（2; 2b; 2c）在其端部（5'）处轴向延伸，位于圆柱形管（3）的内孔（41）中，使用电介质的棒（9; 9a; 9c; 9c）材料。本发明的管状电容器具有增加的介电强度并提高NMR光谱仪的分辨率。

3. 发明授权

US06563317B2 Device for the exact centering of an NMR sample tube 有权
标题翻译：用于NMR样品管精确对中的装置
公开(公告)号：US06563317B2
公开(公告)日：2003-05-13
申请号：US10086558
申请日：2002-03-04
申请人： Michael Warden , Roberto Seydoux , Daniel Marek
发明人： Michael Warden , Roberto Seydoux , Daniel Marek
IPC分类号： G01V300
CPC分类号： G01R33/30 , G01R33/307
摘要： A device for centering an elongated sample tube (8), filled with a measuring substance, relative to the vertical axis of an NMR receiver coil system (9) which is rigidly mounted in a support device, is characterized in that at least two centering devices (13,14) are provided which are separated from each other in an axial direction of the receiver coil axis and act on the sample tube in a radial direction only, one of which is disposed above and the other below the NMR receiver coil system, and at least one positioning devices (16;17) which acts on the sample tube in an exclusively axial direction and which can be located either below or above the NMR receiver coil system, wherein the exclusively radially acting centering devices are rigidly connected to the support device for mounting the NMR receiver coil system. This considerably increases the centering accuracy compared to known devices with simple technical devices to obtain optimum results even for measuring capillary sample tubes which pose the highest requirements in centering accuracy.
摘要翻译：用于使装有测量物质的细长样品管（8）相对于刚性地安装在支撑装置中的NMR接收器线圈系统（9）的垂直轴定心的装置的特征在于，至少两个定心装置（13,14），其在接收器线圈轴线的轴向上彼此分离，并且仅在径向上作用在样品管上，其中一个在NMR接收器线圈系统的上方和另一个之上，以及至少一个定位装置（16; 17），它们在轴向方向作用在样品管上，并且可以位于NMR接收器线圈系统的下方或上方，其中专用径向作用的定心装置刚性地连接到支撑件用于安装NMR接收器线圈系统的装置。与使用简单的技术装置的已知装置相比，这显着提高了定心精度，以便即使在测量对准精度要求最高的毛细管样品管中也能获得最佳结果。

4. 发明授权

US06686740B2 Device for the transport and exact positioning of a sample tube in a high-resolution NMR spectrometer 有权
标题翻译：用于在高分辨率NMR光谱仪中运送和精确定位样品管的装置
公开(公告)号：US06686740B2
公开(公告)日：2004-02-03
申请号：US10086347
申请日：2002-03-04
申请人： Hansjoerg Tschirky , Michael Warden , Roberto Seydoux , Daniel Marek
发明人： Hansjoerg Tschirky , Michael Warden , Roberto Seydoux , Daniel Marek
IPC分类号： G01V300
CPC分类号： G01R33/307
摘要： A device for transporting an elongated sample tube (8) into the measuring chamber (22) of an NMR magnet system comprising a spinner which has an axial through-bore through which the sample tube can be inserted, transported together with the spinner on an air cushion into the measuring chamber, and positioned therein relative to the vertical axis of the NMR receiver coil system (9) is characterized by a mounting sleeve (17) which is disposed in a collar-like manner radially around the sample tube such that it cannot slip and which, in the operating position of the sample tube, flatly abuts with one end face thereof on a horizontal stop surface (18) in the bottom region inside a two-stage axial bore (20) of the spinner (7b), wherein the inner diameter of the bore (20), in a first stage in the upper region, is larger than the outer diameter of the mounting sleeve, and the inner diameter of a second stage, in the bottom region of the spinner, is smaller than the outer diameter of the mounting sleeve but larger than the outer diameter of the sample tube. This permits modification of a transport device for NMR measuring capillaries using simple technical means such that it is less sensitive than the conventional devices to curtail breakage of glass.
摘要翻译：一种用于将细长的样品管（8）输送到包括旋转器的NMR磁体系统的测量室（22）中的装置，该旋转器具有轴向通孔，样品管可穿过该轴向通孔，与旋转器一起在空气垫片进入测量室，并且相对于NMR接收器线圈系统（9）的垂直轴定位在其中，其特征在于安装套筒（17），其以围绕样品管的径向方式设置成使其不能并且在样品管的操作位置，在旋转器（7b）的两级轴向孔（20）内的底部区域的水平止动表面（18）上与样品管的操作位置平坦地邻接在其中，其中在上部区域的第一阶段，孔（20）的内径大于安装套筒的外径，并且在旋转器的底部区域中的第二阶段的内径小于安装座的外径而是大于样品管的外径。这允许使用简单的技术手段修改NMR测量毛细管的运输装置，使得其比常规装置更不易于抑制玻璃破裂。

5. 发明授权

US06426058B1 Enhancement of NMR and MRI in the presence of hyperpolarized noble gases 失效
标题翻译：在超极化稀有气体存在下增强核磁共振和核磁共振
公开(公告)号：US06426058B1
公开(公告)日：2002-07-30
申请号：US08825475
申请日：1997-03-28
申请人： Alexander Pines , Thomas Budinger , Gil Navon , Yi-Qiao Song , Stephan Appelt , Angelo Bifone , Rebecca Taylor , Boyd Goodson , Roberto Seydoux , Toomas Room , Tanja Pietrass
发明人： Alexander Pines , Thomas Budinger , Gil Navon , Yi-Qiao Song , Stephan Appelt , Angelo Bifone , Rebecca Taylor , Boyd Goodson , Roberto Seydoux , Toomas Room , Tanja Pietrass
IPC分类号： A61B505
CPC分类号： G01R33/5601 , A61K49/1815 , G01R33/282 , G01R33/62 , Y10T436/24
摘要： The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
摘要翻译：本发明一般涉及用于光谱和成像的核磁共振（NMR）技术。更具体地，本发明涉及超极化惰性气体（例如Xe和He）用于增强和改善NMR和MRI的方法。此外，本发明的超极化气体溶液在体外和体内都可用于研究系统的动力学或结构。当与体内或体外的生物系统一起使用时，靶向超极化气体并将其递送到系统内的特定区域在本发明的范围内。

6. 发明授权

US06818202B2 Enhancement of NMR and MRI in the presence of hyperpolarized noble gases 失效
标题翻译：在超极化稀有气体存在下增强核磁共振和核磁共振
公开(公告)号：US06818202B2
公开(公告)日：2004-11-16
申请号：US10164324
申请日：2002-06-05
申请人： Alexander Pines , Thomas Budinger , Gil Navon , Yi-Qiao Song , Stephan Appelt , Angelo Bifone , Rebecca Taylor , Boyd Goodson , Roberto Seydoux , Toomas Room , Tanja Pietrass
发明人： Alexander Pines , Thomas Budinger , Gil Navon , Yi-Qiao Song , Stephan Appelt , Angelo Bifone , Rebecca Taylor , Boyd Goodson , Roberto Seydoux , Toomas Room , Tanja Pietrass
IPC分类号： A61B5055
CPC分类号： G01R33/5601 , A61K49/1815 , G01R33/282 , G01R33/62 , Y10T436/24
摘要： The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
摘要翻译：本发明一般涉及用于光谱和成像的核磁共振（NMR）技术。更具体地，本发明涉及超极化惰性气体（例如Xe和He）用于增强和改善NMR和MRI的方法。此外，本发明的超极化气体溶液在体外和体内都可用于研究系统的动力学或结构。当与体内或体外的生物系统一起使用时，靶向超极化气体并将其递送到系统内的特定区域在本发明的范围内。

7. 发明授权

US07385395B2 Apparatus for preparing a solution of a hyperpolarized noble gas for NMR and MRI analysis 有权
标题翻译：用于制备用于NMR和MRI分析的超极化惰性气体溶液的装置
公开(公告)号：US07385395B2
公开(公告)日：2008-06-10
申请号：US10940297
申请日：2004-09-13
申请人： Alexander Pines , Thomas Budinger , Gil Navon , Yi-Qiao Song , Stephan Appelt , Angelo Bifone , Rebecca Taylor , Boyd Goodson , Roberto Seydoux , Toomas Room , Tanja Pietrass
发明人： Alexander Pines , Thomas Budinger , Gil Navon , Yi-Qiao Song , Stephan Appelt , Angelo Bifone , Rebecca Taylor , Boyd Goodson , Roberto Seydoux , Toomas Room , Tanja Pietrass
IPC分类号： G01V3/00 , G01N24/00 , A61B5/055
CPC分类号： G01R33/5601 , A61K49/1815 , G01R33/282 , G01R33/62 , Y10T436/24
摘要： The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
摘要翻译：本发明一般涉及用于光谱和成像的核磁共振（NMR）技术。更具体地，本发明涉及超极化惰性气体（例如Xe和He）用于增强和改善NMR和MRI的方法。此外，本发明的超极化气体溶液在体外和体内都可用于研究系统的动力学或结构。当与体内或体外的生物系统一起使用时，靶向超极化气体并将其递送到系统内的特定区域在本发明的范围内。

8. 发明申请

US20050030026A1 Enhancement of NMR and MRI in the presence of hyperpolarized noble gases 有权
标题翻译：在超极化稀有气体存在下增强核磁共振和核磁共振
公开(公告)号：US20050030026A1
公开(公告)日：2005-02-10
申请号：US10940297
申请日：2004-09-13
申请人： Alexander Pines , Thomas Budinger , Gil Navon , Yi-Qiao Song , Stephan Appelt , Angelo Bifone , Rebecca Taylor , Boyd Goodson , Roberto Seydoux , Toomas Room , Tanja Pietrass
发明人： Alexander Pines , Thomas Budinger , Gil Navon , Yi-Qiao Song , Stephan Appelt , Angelo Bifone , Rebecca Taylor , Boyd Goodson , Roberto Seydoux , Toomas Room , Tanja Pietrass
IPC分类号： G01R33/48 , A61B5/055 , A61K49/18 , G01R33/28 , G01R33/62 , G01V3/00 , A61B5/05
CPC分类号： G01R33/5601 , A61K49/1815 , G01R33/282 , G01R33/62 , Y10T436/24
摘要： The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
摘要翻译：本发明一般涉及用于光谱和成像的核磁共振（NMR）技术。更具体地，本发明涉及超极化惰性气体（例如Xe和He）用于增强和改善NMR和MRI的方法。此外，本发明的超极化气体溶液在体外和体内都可用于研究系统的动力学或结构。当与体内或体外的生物系统一起使用时，靶向超极化气体并将其递送到系统内的特定区域在本发明的范围内。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式