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    • 6. 发明授权
    • Degradation and protection of organic compounds mediated by low
molecular weight chelators
    • 由低分子量螯合剂介导的有机化合物的降解和保护
    • US6046375A
    • 2000-04-04
    • US838771
    • 1997-04-10
    • Barry S. GoodellJody L. JellisonJing LiuSrinivasan Krishnamurthy
    • Barry S. GoodellJody L. JellisonJing LiuSrinivasan Krishnamurthy
    • B09C1/08C02F1/68C02F1/72C02F1/78A62D3/00
    • B09C1/08C02F1/683C02F1/722C02F1/78C02F2101/36Y10S210/909
    • A method of forming reactive oxygen species by solubilizing a metal ion from a metal oxy(hydr)oxide compound with an iron oxy(hydr)oxide solubilizing chelator to yield a first soluble metal ion chelate complex. The metal ion is transferred from the chelate complex to a free redox cycling chelator to form a second metal ion chelate complex which reduces the metal ion to a reduced metal species. The reduced metal species is reacted with an oxygen containing oxidant to yield a free redox cycling chelator and a reactive oxygen species. The reactive oxygen species may be used to oxidize a target substrate. The preferred metal ion is a cationic transition metal, such as iron or manganese. A preferred iron oxy(hydr)oxide solubilizing chelator is oxalic acid. The method is generally performed at acidic pH. Also provided is a method of protecting an organic composition from reactive oxygen species comprising impregnating the composition with a redox cycling chelator able to form a reduced metal ion chelate complex with a metal ion, the chelator present in an amount sufficient to protect the composition from degradation from reactive oxygen species such as hydroxyl radical or superoxide anion.
    • 通过用氧化铁(hydr)氧化物增溶螯合剂溶解金属氧化(氢氧化物)化合物的金属离子形成活性氧的方法,得到第一可溶性金属离子螯合络合物。 金属离子从螯合络合物转移到游离的氧化还原循环螯合剂中以形成第二金属离子螯合络合物,其将金属离子还原为还原的金属物质。 还原的金属物质与含氧氧化剂反应以产生游离的氧化还原循环螯合剂和活性氧。 活性氧可用于氧化靶基质。 优选的金属离子是阳离子过渡金属,例如铁或锰。 优选的氧化铁(hydr)氧化物增溶螯合剂是草酸。 该方法通常在酸性pH下进行。 还提供了一种保护有机组合物免受活性氧的方法,包括用能够与金属离子形成还原的金属离子螯合物的氧化还原循环螯合剂浸渍组合物,该螯合剂以足以保护组合物免于降解的量存在 来自活性氧,如羟基或超氧阴离子。