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1. 发明申请

US20090009758A1 OPAQUE ADDITIVE TO BLOCK STRAY LIGHT IN TEFLON AF LIGHT-GUIDING FLOWCELLS 有权
标题翻译：在TEFLON AF轻型流动池中增加块状光
公开(公告)号：US20090009758A1
公开(公告)日：2009-01-08
申请号：US12043434
申请日：2008-03-06
申请人： Anthony C. Gilby
发明人： Anthony C. Gilby
IPC分类号： G01N21/01
CPC分类号： G01N21/552 , G01N21/0303 , G01N21/05 , G01N30/74 , G01N2021/0346 , G01N2021/052 , G01N2201/064
摘要： The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped Teflon® AF, or “black Teflon® AF,” for all or part of the walls of a light-guiding flowcell adapted for use in HPLC absorbance detection.
摘要翻译：本发明涉及使用光吸收壁材料来消除导光结构中的杂散光路径，例如用于HPLC吸光度检测的那些。更具体地，本发明涉及适用于HPLC吸光度检测的导光流动池的全部或部分壁的碳掺杂特氟隆AF或“黑色特氟隆AF”的用途。

2. 发明授权

US07251026B2 Fluorescence detector geometry 有权
标题翻译：荧光检测器几何
公开(公告)号：US07251026B2
公开(公告)日：2007-07-31
申请号：US10650213
申请日：2003-08-28
申请人： Anthony C. Gilby
发明人： Anthony C. Gilby
IPC分类号： G01N1/10
CPC分类号： G01N21/0303 , G01J3/02 , G01J3/0208 , G01J3/18 , G01J3/4406 , G01N21/031 , G01N21/05 , G01N21/645 , G01N30/74 , G01N2021/0314 , G01N2021/0346 , G01N2021/6482
摘要： Excitation light of a selected wavelength from an excitation monochromator is directed along the long axis of a flow cell containing the sample to be analyzed, generating fluorescence. An emission monochromator is positioned at right angles to the plane of the excitation monochromator and receives the fluorescence from the flow cell utilizing optical components positioned such that the entrance slit of the emission monochromator is aligned with the long axis of the emission window. The intensity of the output from the flow cell is further maximized by positioning a retro-reflecting mirror at the end of the flow channel to effectively double the path-length of the excitation beam, and a reflecting surface on the side of the cell opposite the emission window to increase the collection efficiency and thereby increase the sensitivity of the detector.
摘要翻译：来自激发单色仪的所选波长的激发光沿着包含待分析样品的流动池的长轴被引导，产生荧光。发射单色仪被定位成与激发单色仪的平面成直角，并且利用定位成使得发射单色仪的入射狭缝与发射窗的长轴对准的来自流动池的荧光接收。通过在流动通道的端部定位回射反射镜以有效地使激励光束的路径长度倍增，并且与单元的相反侧的反射表面相反，来自流动池的输出的强度进一步最大化发射窗口，以提高收集效率，从而提高检测器的灵敏度。

3. 发明授权

US5900934A Capillary chromatography detector apparatus 失效
公开(公告)号：US5900934A
公开(公告)日：1999-05-04
申请号：US947455
申请日：1997-10-06
申请人： Anthony C. Gilby , William W. Carson
发明人： Anthony C. Gilby , William W. Carson
IPC分类号： G01N27/447 , G01N30/46 , G01N30/74 , G01N21/01
CPC分类号： G01N27/44721 , G01N27/44782 , G01N30/74
摘要： An apparatus to effect multiple simultaneous separations to measure absorbance, comprising a photodetector array comprising a plurality of photosensitive elements connected to provide a serial output. The elements are typically pixels of a photodiode array (PDA). The elements are illuminated by a light source positioned to illuminate at least a portion of the photodetector array. The light source may be a an AC or DC mercury lamp or other useable light source for chromatography. An array of separation channels is disposed between the light source and the photodetector array, each of the separation channels having a lumen, a sample introduction end and a detection region disposed opposite the sample introduction end. Typically and as disclosed herein the array is a multiple parallel capillary electrophoresis system. The last element is a mask element having at least one aperture for each associated separation channel, each aperture corresponding to its associated separation channel thereby selectively permitting light from the light source to pass through the lumen of its associated separation channel, at least a portion of the light passing through the lumen of the associated separation channel falling on a respective photosensitive element of the photodetector array to effect measurement of absorption of light by a sample introduced into the sample introduction end of the associated separation channel. Also disclosed is an instrument for analyzing the spectral content of chemical samples contained in a large number of capillary tubes which uses a single AC powered light source (which therefore gives a time-varying light output) and a single self-scanned PDA detector. This greatly reduces the number of circuit elements required, since only one amplifier, one A/D converter, one light source and one detector need be provided. The resulting device can be constructed less expensively and take up less space as compared to the conventional system. Further, a control signal having a particular frequency is supplied to both the power supply of the AC light source and the PDA detector. This stabilizes the detector signal's baseline.

4. 发明授权

US5194915A Photometric apparatus and process 失效
标题翻译：光度仪和过程
公开(公告)号：US5194915A
公开(公告)日：1993-03-16
申请号：US585465
申请日：1990-09-20
申请人： Anthony C. Gilby
发明人： Anthony C. Gilby
IPC分类号： G01N21/05 , G01N21/64 , G01N21/85 , G01N27/447 , G01N30/74 , G02B6/032
CPC分类号： G01N27/44721 , G01N21/64 , G01N21/85 , G01N30/74 , G02B6/032 , G01N2021/052 , G01N2021/6467 , G01N2021/8557 , G01N2030/746 , G02B2006/0325
摘要： A photometric apparatus is provided for analyzing a sample liquid capable of fluorescing when exposed to excitation light. The sample liquid, surrounded by a sheath liquid under conditions of laminar flow to form an interface between the sample liquid and the sheath is passed through a cell conduit. An excitation light is directed axially into the sample liquid and is totally internally reflected at the interface with the sheath liquid. The sample fluoresces in response to the excitation light and fluorescent emission is observed through the sheath liquid.
摘要翻译：提供了一种用于分析当暴露于激发光时能够发荧光的样品液体的测光装置。在层流条件下由鞘液包围以形成样品液体和护套之间的界面的样品液体通过细胞管道。激发光轴向引导到样品液体中，并且在与鞘液体的界面处完全内部反射。样品响应于激发光而发荧光，并且通过鞘液观察到荧光发射。

5. 发明授权

US4831252A Aligning optical and mechanical elements for optical motion sensing 失效
标题翻译：对准用于光学运动感测的光学和机械元件
公开(公告)号：US4831252A
公开(公告)日：1989-05-16
申请号：US149787
申请日：1988-01-29
申请人： Dale E. Ihnat , Anthony C. Gilby , Richard A. Anderson
发明人： Dale E. Ihnat , Anthony C. Gilby , Richard A. Anderson
IPC分类号： G01D5/26
CPC分类号： G01D5/268 , Y10S430/146
摘要： A technique is disclosed for achieving critical alignment of optical and mechanical elements, in which one of the foregoing is movable with respect to the other. Specifically, an optical fiber (12) is aligned with respect to a movable member (19) in a first position. The movable member is then displaced to a second position and high levels of radiant energy at a first discernible wavelength are transmitted down the fiber optic path to alter, or pattern, a wavelength sensitive surface area or coating (16) on the surface of the movable member. The movable member is then freed, and radiant energy of a second wavelength to which the coating is insensitive is used to sense the position of the movable member with respect to the fiber optic.
摘要翻译：公开了一种用于实现光学和机械元件的临界对准的技术，其中上述之一可相对于另一个移动。具体而言，光纤（12）在第一位置相对于可动部件（19）对准。然后可移动构件移动到第二位置，并且在第一可识别波长处的高水平的辐射能量向下传送到光纤路径，以改变或图案化可移动的表面上的波长敏感表面积或涂层（16）会员。然后可移动部件被释放，并且使用涂层不敏感的第二波长的辐射能来感测可移动部件相对于光纤的位置。

6. 发明授权

US4521684A Optical measurement system with light-driven vibrating sensor element 失效
标题翻译：具有光驱振动传感器元件的光学测量系统
公开(公告)号：US4521684A
公开(公告)日：1985-06-04
申请号：US350687
申请日：1982-02-22
申请人： Anthony C. Gilby , Edward L. Lewis , Everett O. Olsen
发明人： Anthony C. Gilby , Edward L. Lewis , Everett O. Olsen
IPC分类号： G01H9/00 , G01H13/00 , G01L1/08 , G01L1/10 , G02B5/14
CPC分类号： G01L1/103 , G01L1/08
摘要： An instrumentation system for use in measuring and processing industrial process variables, such as flow, pressure, or temperature, includes a resonant element sensor whose resonant frequency varies in accordance with changes in the desired process variable communicating through an optical fiber link to a distant control room. The sensor is activated into resonant physical motion by light energy from a source in the control room, while the motion of the wire is sensed optically and retransmitted to the control room to produce an output signal whose frequency is equal to that of the resonating element. A feedback network maintains the sensor in resonance by synchronizing the delivery of light energy to the motion of the resonant element. The powering and sensing aspect may be performed by individual fiber optic cables or alternatively this function may be combined by utilizing a single fiber optic strand.
摘要翻译：用于测量和处理诸如流量，压力或温度的工业过程变量的仪表系统包括谐振元件传感器，其谐振频率根据通过光纤链路传输到远程控制器的期望过程变量的变化而变化房间。传感器通过来自控制室中的源的光能被激活成共振的物理运动，同时光线的运动被光学地感测并重新发送到控制室，以产生频率等于谐振元件的输出信号。反馈网络通过将光能的传递与谐振元件的运动同步来使传感器保持谐振。功率和感测方面可以由单独的光纤电缆执行，或者该功能可以通过利用单个光纤线组合。

7. 再颁专利

USRE44253E1 Self-scanned photodiode array with selectively-skipped pixels 有权
标题翻译：具有有选择跳过像素的自扫描光电二极管阵列
公开(公告)号：USRE44253E1
公开(公告)日：2013-06-04
申请号：US13247397
申请日：2011-09-28
申请人： Anthony C. Gilby
发明人： Anthony C. Gilby
IPC分类号： H04N5/335
摘要： A self scanning photodiode array allows low signal pixels to accumulate charge for multiples of predetermined exposure time t0 before being read. The pattern of exposures, the integers Mi where I runs from 1 to N the number of pixels in the array, is chosen such that the pixels of interest accumulate as much charge as possible without exceeding saturation.
摘要翻译：自扫描光电二极管阵列允许低信号像素在读取之前对预定曝光时间t0的倍数累积电荷。曝光模式，其中我从1到N运行数组中的像素数的整数Mi，使得感兴趣的像素在不超过饱和的情况下累积尽可能多的电荷。

8. 发明授权

US08401346B2 Methods of making and using an apparatus and devices for placing light and sample in photo-emitting or absorbing device 有权
标题翻译：制造和使用将光和样品放置在光发射或吸收装置中的装置和装置的方法
公开(公告)号：US08401346B2
公开(公告)日：2013-03-19
申请号：US12917007
申请日：2010-11-01
申请人： Anthony Jeannotte , Anthony C. Gilby , Theordore A. Dourdeville , Dennis DellaRovere , John Leason
发明人： Anthony Jeannotte , Anthony C. Gilby , Theordore A. Dourdeville , Dennis DellaRovere , John Leason
IPC分类号： G02B6/00
CPC分类号： G02B6/4248 , G01N30/74 , G01N2030/746 , G02B6/3897
摘要： The present invention relates to a device having an optical fiber coupled to a high pressure containment vessel and a method for making the same. The high pressure containment vessel can be an optical fiber based flow cell for a chromatography system.
摘要翻译：本发明涉及一种具有耦合到高压容器的光纤的装置及其制造方法。高压容纳容器可以是用于色谱系统的基于光纤的流动池。

9. 发明授权

US08289511B2 Light-guiding flowcells with minimal stray light 有权
标题翻译：具有最小杂散光的导光流通池
公开(公告)号：US08289511B2
公开(公告)日：2012-10-16
申请号：US13336013
申请日：2011-12-23
申请人： Anthony C. Gilby
发明人： Anthony C. Gilby
IPC分类号： G01N1/10 , G01N21/01
CPC分类号： G01N21/552 , G01N21/0303 , G01N21/05 , G01N30/74 , G01N2021/0346 , G01N2021/052 , G01N2201/064
摘要： The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped Teflon® AF, or “black Teflon® AF,” for all or part of the walls of a light-guiding flowcell adapted for use in HPLC absorbance detection.
摘要翻译：本发明涉及使用光吸收壁材料来消除导光结构中的杂散光路径，例如用于HPLC吸光度检测的那些。更具体地，本发明涉及适用于HPLC吸光度检测的导光流动池的全部或部分壁的碳掺杂Teflon AF或黑色Teflon AF的用途。

10. 发明授权

US08107067B2 Opaque additive to block stray light in teflon AF light-guiding flowcells 有权
标题翻译：在聚四氟乙烯AF导光流通池中阻挡杂散光的不透明添加剂
公开(公告)号：US08107067B2
公开(公告)日：2012-01-31
申请号：US12043434
申请日：2008-03-06
申请人： Anthony C. Gilby
发明人： Anthony C. Gilby
IPC分类号： G01N1/10
CPC分类号： G01N21/552 , G01N21/0303 , G01N21/05 , G01N30/74 , G01N2021/0346 , G01N2021/052 , G01N2201/064
摘要： The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped Teflon® AF, or “black Teflon® AF,” for all or part of the walls of a light-guiding flowcell adapted for use in HPLC absorbance detection.
摘要翻译：本发明涉及使用光吸收壁材料来消除导光结构中的杂散光路径，例如用于HPLC吸光度检测的那些。更具体地，本发明涉及适用于HPLC吸光度检测的导光流动池的全部或部分壁的碳掺杂Teflon AF或“黑色Teflon AF”的用途。

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