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1. 发明授权

US07836888B2 Airway implant and methods of making and using 有权
标题翻译：气道植入及其使用方法
公开(公告)号：US07836888B2
公开(公告)日：2010-11-23
申请号：US10946435
申请日：2004-09-21
申请人： Anant V. Hegde , George Y. Choi , Wally S. Buch
发明人： Anant V. Hegde , George Y. Choi , Wally S. Buch
IPC分类号： A61F5/56
CPC分类号： A61L31/125 , A61B2017/248 , A61C7/00 , A61F2/00 , A61F5/56 , A61F5/566 , A61F2210/0023 , A61L31/14 , A61N1/0517 , A61N1/0519 , A61N1/0548 , A61N1/3601 , Y10S602/902
摘要： A system and device for maintaining and/or creating patency in airways is disclosed. The methods of using the system and device are also disclosed. The system includes a power source that energizes a electro-active polymer implant. The energized polymer implant provides stiffness and shape to the airway, thereby minimizing collapse or deformation of the airway. A method of making the device is also disclosed.
摘要翻译：公开了一种用于在气道中维持和/或产生通畅的系统和装置。还公开了使用该系统和装置的方法。该系统包括为电活性聚合物植入物通电的电源。通电的聚合物植入物为气道提供刚度和形状，从而最小化气道的塌陷或变形。还公开了制造该器件的方法。

2. 发明申请

US20090078275A1 Palatal Implant Fixation Devices and Methods 审中-公开
标题翻译：腭植入物固定装置及方法
公开(公告)号：US20090078275A1
公开(公告)日：2009-03-26
申请号：US12239599
申请日：2008-09-26
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Wally S. Buch , James B. Ross
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Wally S. Buch , James B. Ross
IPC分类号： A61F5/56
CPC分类号： A61B5/682 , A61B5/0031 , A61B5/076 , A61B5/4547 , A61B5/4818 , A61B5/6882 , A61C7/10 , A61F2/02 , A61F5/566
摘要： Devices and methods for securing an implant to the hard palate are disclosed. The device may use a bracket and a retention element, such as a screw or tack, for retaining the device to the hard palate. The device may include a housing and an actuator element for actuating a portion of the soft palate. The method may include securing the retention element into the hard palate.
摘要翻译：公开了用于将植入物固定到硬腭的装置和方法。该装置可以使用支架和保持元件，例如螺钉或钉，用于将装置保持在硬腭上。该装置可以包括壳体和用于致动软腭的一部分的致动器元件。该方法可以包括将保持元件固定到硬腭中。

3. 发明申请

US20100319711A1 AIRWAY IMPLANT AND METHODS OF MAKING AND USING 审中-公开
公开(公告)号：US20100319711A1
公开(公告)日：2010-12-23
申请号：US12821912
申请日：2010-06-23
申请人： Anant V. Hegde , George S. Choi , Wally S. Buch
发明人： Anant V. Hegde , George S. Choi , Wally S. Buch
IPC分类号： A61F5/56
CPC分类号： A61L31/125 , A61B2017/248 , A61C7/00 , A61F2/00 , A61F5/56 , A61F5/566 , A61F2210/0023 , A61L31/14 , A61N1/0517 , A61N1/0519 , A61N1/0548 , A61N1/3601 , Y10S602/902
摘要： A system and device for maintaining and/or creating patency in airways is disclosed. The methods of using the system and device are also disclosed. The system includes a power source that energizes a electro-active polymer implant. The energized polymer implant provides stiffness and shape to the airway, thereby minimizing collapse or deformation of the airway. A method of making the device is also disclosed.
摘要翻译：公开了一种用于在气道中维持和/或产生通畅的系统和装置。还公开了使用该系统和装置的方法。该系统包括为电活性聚合物植入物通电的电源。通电的聚合物植入物为气道提供刚度和形状，从而最小化气道的塌陷或变形。还公开了制造该器件的方法。

4. 发明申请

US20090259093A1 ARTIFICIAL SPHINCTER WITH PIEZOELECTRIC ACTUATOR 审中-公开
标题翻译：人造肩带压电致动器
公开(公告)号：US20090259093A1
公开(公告)日：2009-10-15
申请号：US12420744
申请日：2009-04-08
申请人： Nikhil D. Bhat , Anant V. Hegde , George Yoseung Choi , Wally S. Buch
发明人： Nikhil D. Bhat , Anant V. Hegde , George Yoseung Choi , Wally S. Buch
IPC分类号： A61F2/02
CPC分类号： A61F2/0036 , A61F2250/0002 , A61F2250/001
摘要： A biologically implantable artificial sphincter system and methods of using the same is disclosed. The artificial sphincter system disclosed herein comprises a sphincter band and a piezoelectric element, both of which are adapted and configured for coordinated operation to open and/or close a body cavity. The artificial sphincter systems are useful in the treatment of urinary incontinence, fecal incontinence, and reflux disorders. The implanted artificial sphincter can also provide a signal to the recipient to urinate or defecate.
摘要翻译：公开了一种生物可植入人造括约肌系统及其使用方法。本文公开的人造括约肌系统包括括约肌带和压电元件，两者都适于和构造成用于协调操作以打开和/或关闭体腔。人造括约肌系统可用于治疗尿失禁，大便失禁和反流疾病。植入的人造括约肌还可以向接受者提供小便或排便的信号。

5. 发明授权

US07198595B2 Cardiac apparatus including electroactive polymer actuators and methods of using the same 失效
标题翻译：包括电活性聚合物致动器的心脏设备及其使用方法
公开(公告)号：US07198595B2
公开(公告)日：2007-04-03
申请号：US10810134
申请日：2004-03-26
申请人： Anant V. Hegde , Wally S. Buch , Halil I. Karabey
发明人： Anant V. Hegde , Wally S. Buch , Halil I. Karabey
IPC分类号： A61N1/362
CPC分类号： A61F2/2481 , A61B2017/00398 , A61B2017/00871 , A61M1/1053 , A61M1/1058 , A61M1/1068 , A61M1/12 , A61M2205/0283
摘要： Cardiac apparatus and methods of using such cardiac apparatus are described. In one embodiment, a cardiac apparatus includes a covering that is configured to at least partially encircle a heart with a first portion of the covering adjacent to a second portion of the covering. The cardiac apparatus also includes an electroactive polymer actuator. A first end of the electroactive polymer actuator is coupled to the first portion of the covering, and a second end of the electroactive polymer actuator is coupled to the second portion of the covering. The second end of the electroactive polymer actuator is oriented such that, upon actuation of the electroactive polymer actuator, the second end of the electroactive polymer actuator extends away from the first end of the electroactive polymer actuator to move the second portion of the covering towards the first portion of the covering.
摘要翻译：描述了使用这种心脏装置的心脏装置和方法。在一个实施例中，心脏设备包括被配置为至少部分地围绕心脏的覆盖物，其中覆盖物的第一部分与覆盖物的第二部分相邻。心脏装置还包括电活性聚合物致动器。电活性聚合物致动器的第一端耦合到覆盖物的第一部分，并且电活性聚合物致动器的第二端耦合到覆盖物的第二部分。电活性聚合物致动器的第二端被定向成使得在电活性聚合物致动器致动时，电活性聚合物致动器的第二端延伸离开电活性聚合物致动器的第一端，以将覆盖物的第二部分朝向覆盖物的第一部分。

6. 发明授权

US06527761B1 Methods and devices for obstructing and aspirating lung tissue segments 有权
标题翻译：用于阻塞和吸入肺组织段的方法和装置
公开(公告)号：US06527761B1
公开(公告)日：2003-03-04
申请号：US09699302
申请日：2000-10-27
申请人： Peter P. Soltesz , Robert Kotmel , Tony Wondka , Michael P. Reilly , Wally S. Buch
发明人： Peter P. Soltesz , Robert Kotmel , Tony Wondka , Michael P. Reilly , Wally S. Buch
IPC分类号： A61M3500
CPC分类号： A61B17/12172 , A61B17/12022 , A61B17/12104 , A61B17/12136 , A61B17/12159 , A61B17/1219 , A61B2017/1205 , A61B2017/22067 , A61B2017/22068
摘要： Methods, systems, devices and kits for performing lung volume reduction in patients suffering from chronic obstructive pulmonary disease or other conditions using and comprising minimally invasive instruments introduced through the mouth (endotracheally) to isolate a target lung tissue segment from other regions of the lung and reduce lung volume. Isolation is achieved by deploying an obstructive device in a lung passageway leading to the target lung tissue segment. Once the obstructive device is anchored in place, the segment can be aspirated through the device. This may be achieved by a number of methods, including coupling an aspiration catheter to an inlet port on the obstruction device and aspirating through the port. Or, providing the port with a valve which allows outflow of gas from the isolated lung tissue segment during expiration of the respiratory cycle but prevents inflow of air during inspiration. In addition, a number of other methods may be used. The obstructive device may remain as an implant, to maintain isolation and optionally allow subsequent aspiration, or the device maybe removed at any time.
摘要翻译：用于在患有慢性阻塞性肺病或其他病症的患者中进行肺容积减小的方法，系统，装置和试剂盒，其使用和包括通过口引入的微创器械（气管内）以将目标肺组织区段与肺的其他区域隔离，减少肺容量。通过在通向目标肺组织段的肺通道中展开阻塞装置来实现隔离。一旦阻塞装置固定在适当位置，则可以通过装置吸入该段。这可以通过许多方法来实现，包括将吸入导管联接到阻塞装置上的入口端口并通过端口抽吸。或者，为端口提供阀，其允许在呼吸周期期间从隔离的肺组织段流出气体，但是防止在吸气期间空气的流入。此外，可以使用许多其它方法。阻塞装置可以保留为植入物，以保持隔离并且可选地允许随后的吸入，或者可以随时移除该装置。

7. 发明授权

US06517558B2 Methods and devices for forming vascular anastomoses 失效
标题翻译：用于形成血管吻合的方法和装置
公开(公告)号：US06517558B2
公开(公告)日：2003-02-11
申请号：US09776230
申请日：2001-02-01
申请人： Darin C. Gittings , Wally S. Buch , Alan R. Rapacki
发明人： Darin C. Gittings , Wally S. Buch , Alan R. Rapacki
IPC分类号： A61B1702
CPC分类号： A61B17/11 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61F2/064 , A61F2/07 , A61F2/86 , A61F2/91
摘要： Methods and devices for forming an anastomosis utilize a graft vessel secured to a vessel coupling that is fixed to a target vessel without using suture. The vessel coupling may be collapsed for introduction into the target vessel and then expanded to engage the vessel wall. The vessel coupling may be a stent attached to a graft vessel to form a stent-graft assembly. The anastomosis may be carried out to place the graft and target vessels in fluid communication while preserving native proximal flow through the target vessel, which may be a coronary artery. As a result, blood flowing through the coronary artery from the aorta is not blocked by the vessel coupling and thus is free to move past the site of the anastomosis.
摘要翻译：用于形成吻合的方法和装置利用固定到血管联接的移植血管，所述移植血管在不使用缝合线的情况下固定到靶血管。血管联接器可能被塌缩以引入目标血管，然后膨胀以接合血管壁。血管联接可以是附接到移植血管以形成支架移植物组件的支架。可以进行吻合以使移植物和靶容器保持流体连通，同时保持通过可能是冠状动脉的靶血管的天然近端流。结果，从主动脉流过冠状动脉的血液不被血管联接阻塞，因此可以自由地移动通过吻合部位。

8. 发明授权

US06997918B2 Methods and devices for obstructing and aspirating lung tissue segments 有权
标题翻译：用于阻塞和吸入肺组织段的方法和装置
公开(公告)号：US06997918B2
公开(公告)日：2006-02-14
申请号：US10382131
申请日：2003-03-04
申请人： Peter P. Soltesz , Robert Kotmel , Tony Wondka , Michael P. Reilly , Wally S. Buch
发明人： Peter P. Soltesz , Robert Kotmel , Tony Wondka , Michael P. Reilly , Wally S. Buch
IPC分类号： A61M31/00
CPC分类号： A61B17/12172 , A61B17/12022 , A61B17/12104 , A61B17/12136 , A61B17/12159 , A61B17/1219 , A61B2017/1205 , A61B2017/22067 , A61B2017/22068
摘要： The present invention provides improved methods, systems, devices and kits for performing lung volume reduction in patients suffering from chronic obstructive pulmonary disease or other conditions where isolation of a lung segment or reduction of lung volume is desired. The methods are minimally invasive with instruments being introduced through the mouth (endotracheally) and rely on isolating the target lung tissue segment from other regions of the lung. Isolation is achieved by deploying an obstructive device in a lung passageway leading to the target lung tissue segment. Once the obstructive device is anchored in place, the segment can be aspirated through the device. This may be achieved by a number of methods, including coupling an aspiration catheter to an inlet port on the obstruction device and aspirating through the port. Or, providing the port with a valve which allows outflow of gas from the isolated lung tissue segment during expiration of the respiratory cycle but prevents inflow of air during inspiration. In addition, a number of other methods may be used. The obstructive device may remain as an implant, to maintain isolation and optionally allow subsequent aspiration, or the device may be removed at any time.
摘要翻译：本发明提供了改善的方法，系统，装置和用于在患有慢性阻塞性肺疾病或其它需要肺部分离或减少肺容积的其它病症的患者中进行肺容量减小的试剂盒。这些方法是微创的，仪器通过口腔（气管内）引入，并且依赖于将目标肺组织区段与肺的其它区域分离。通过在通向目标肺组织段的肺通道中展开阻塞装置来实现隔离。一旦阻塞装置固定在适当位置，则可以通过装置吸入该段。这可以通过许多方法来实现，包括将吸入导管联接到阻塞装置上的入口端口并通过端口抽吸。或者，为端口提供阀，其允许在呼吸周期期间从隔离的肺组织段流出气体，但是防止在吸气期间空气的流入。此外，可以使用许多其它方法。阻塞装置可以保留为植入物，以保持隔离并且可选地允许随后的抽吸，或者可以在任何时间移除装置。

9. 发明授权

US08512360B2 Conduits for use in placing a target vessel in fluid communication with source of blood 失效
标题翻译：用于放置目标血管与血液源流体连通的导管
公开(公告)号：US08512360B2
公开(公告)日：2013-08-20
申请号：US10778723
申请日：2004-02-13
申请人： A. Adam Sharkawy , Dean F. Carson , Darin C. Gittings , Keke J. Lepulu , Mark J. Foley , Wally S. Buch , Alan R. Rapacki
发明人： A. Adam Sharkawy , Dean F. Carson , Darin C. Gittings , Keke J. Lepulu , Mark J. Foley , Wally S. Buch , Alan R. Rapacki
IPC分类号： A61B17/08 , A61M5/00
CPC分类号： A61F2/94 , A61B17/11 , A61B2017/00247 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61B2018/00392 , A61F2/064 , A61F2/24 , A61F2/2493 , A61F2002/30079 , A61F2210/009 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2230/0058 , A61F2230/0076
摘要： Methods and devices for placing a target vessel in fluid communication with a source of blood and a target vessel. A conduit includes first portion adapted to be placed in fluid communication with a source of blood, such as a heart chamber, and a second portion adapted to be placed in fluid communication with a target vessel having a lumen, such as coronary artery. The first and second conduit portions are transverse to each other such that the conduit is generally T-shaped. The conduit lies on an exterior of the heart between the blood source and the target vessel and is configured to deliver blood in multiple directions into the lumen of the target vessel. For example, in an occluded coronary artery, blood flows both toward and away from the occlusion. The conduit may be flexible, rigid, collapsible or non-collapsible, and may be formed of synthetic vascular graft material, tissue, or a combination of the two. A conduit delivery device is disclosed for deploying the conduit in a target vessel and perfusing the vessel during such deployment.
摘要翻译：用于放置目标血管与血液源和靶血管流体连通的方法和装置。导管包括适于与诸如心脏腔的血液源流体连通的第一部分和适于与具有诸如冠状动脉的内腔的靶血管流体连通的第二部分。第一和第二导管部分彼此横向，使得导管通常为T形。导管位于血液源和目标血管之间的心脏外部，并被构造成将多个方向的血液输送到目标血管的内腔中。例如，在闭塞的冠状动脉中，血液朝向和远离闭塞流动。导管可以是柔性的，刚性的，可收缩的或不可折叠的，并且可以由合成的血管移植物材料，组织或两者的组合形成。公开了一种导管输送装置，用于将导管部署在靶容器中并且在这种部署期间灌注容器。

10. 发明授权

US07578828B2 Methods and devices for placing a conduit in fluid communication with a target vessel 失效
公开(公告)号：US07578828B2
公开(公告)日：2009-08-25
申请号：US10441256
申请日：2003-05-19
申请人： Darin C. Gittings , Alan R. Rapacki , Dean F. Carson , David H. Cole , Keke Lepulu , Adam Sharkawy , Gilbert S. Laroya , Wally S. Buch
发明人： Darin C. Gittings , Alan R. Rapacki , Dean F. Carson , David H. Cole , Keke Lepulu , Adam Sharkawy , Gilbert S. Laroya , Wally S. Buch
IPC分类号： A61B17/08
CPC分类号： A61F2/95 , A61B17/11 , A61B2017/00243 , A61B2017/00252 , A61B2017/00867 , A61B2017/1107 , A61B2017/1135 , A61B2017/1205 , A61B2017/2923 , A61F2/064 , A61F2/07 , A61F2/86 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2002/9517 , A61F2220/0008 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054
摘要： Methods and devices for placing a conduit in fluid communication with a target vessel and a source of blood, such as the aorta or a heart chamber. The device may be actuated using one hand to place the conduit. The invention allows air in the conduit to be removed prior to placement of the conduit. The invention deploys the conduit in the target vessel by moving a sheath in a distal direction and then in a proximal direction. A conduit is provided with a reinforcing member to prevent kinking of the conduit, and a structure for preventing blockage of the conduit by tissue. A vessel coupling may be used to secure a conduit to a target vessel so as to preserve native blood flow through the vessel, and the conduit may be placed in fluid communication with a target vessel via a laparoscopic or endoscopic procedure.

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