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1. 发明授权

US08318441B2 Fibrinogen alpha and hemoglobin polypeptides as cancer markers 有权
标题翻译：纤维蛋白原α和血红蛋白多肽作为癌症标志物
公开(公告)号：US08318441B2
公开(公告)日：2012-11-27
申请号：US12753527
申请日：2010-04-02
申请人： Alexander Miron , James Dirk Iglehart , Lyndsay N. Harris , Xin Lu , Qian Shi
发明人： Alexander Miron , James Dirk Iglehart , Lyndsay N. Harris , Xin Lu , Qian Shi
IPC分类号： G01N33/53
CPC分类号： G01N33/57407 , G01N2333/75 , G01N2333/805 , G01N2800/44
摘要： The present invention provides methods of detecting cancer using biomarkers.
摘要翻译：本发明提供使用生物标志物检测癌症的方法。

2. 发明申请

US20100248271A1 Fibrinogen Alpha and Hemoglobin Polypeptides as Cancer Markers 有权
标题翻译：纤维蛋白原α和血红蛋白多肽作为肿瘤标志物
公开(公告)号：US20100248271A1
公开(公告)日：2010-09-30
申请号：US12753527
申请日：2010-04-02
申请人： Alexander Miron , James D. Iglehart , Lyndsay N. Harris , Xin Lu , Qian Shi
发明人： Alexander Miron , James D. Iglehart , Lyndsay N. Harris , Xin Lu , Qian Shi
IPC分类号： G01N33/53 , G01N23/00 , G01N33/48 , G01N27/26
CPC分类号： G01N33/57407 , G01N2333/75 , G01N2333/805 , G01N2800/44
摘要： The present invention provides methods of detecting cancer using biomarkers.
摘要翻译：本发明提供使用生物标志物检测癌症的方法。

3. 发明授权

US09446127B2 Compositions including androgen receptor degradation (ARD) enhancers and methods of prophylactic or therapeutic treatment of skin disorders and hair loss 有权
公开(公告)号：US09446127B2
公开(公告)日：2016-09-20
申请号：US12221396
申请日：2008-07-31
申请人： Charles C. Y. Shih , Ching-Yuan Su , Hui-Kang Wang , Qian Shi
发明人： Charles C. Y. Shih , Ching-Yuan Su , Hui-Kang Wang , Qian Shi
IPC分类号： A61K9/127 , A61K31/12 , A61K31/34 , A61K31/7048 , A61K38/16 , A61K45/06 , A61K31/265
CPC分类号： A61K31/216 , A61K9/0014 , A61K9/0019 , A61K9/0053 , A61K31/12 , A61K31/265 , A61K45/06 , A61K2300/00
摘要： The present invention includes methods and compositions useful for treating and preventing skin disorders, hair loss and other skin disorders. The compositions include an ARD enhancer in combination with a second compound or composition. In some embodiments the second compound is at least one of a bactericide, an antibiotic, an anti-microbial peptide, Vitamin A, a Vitamin A derivative, a retinoid, an anti-inflammatory compound, and anti-androgen compounds.

4. 发明授权

US09378344B2 Method and apparatus for protecting information based on data card 有权
标题翻译：基于数据卡保护信息的方法和装置
公开(公告)号：US09378344B2
公开(公告)日：2016-06-28
申请号：US13259931
申请日：2010-05-21
申请人： Qian Shi
发明人： Qian Shi
IPC分类号： G06F7/04 , G06F21/31 , G06F21/79
CPC分类号： G06F21/31 , G06F21/79
摘要： The present invention discloses a method and apparatus for protecting information based on a data card, and the method comprises: selecting information which needs to be hidden in a terminal device; and storing said information which needs to be hidden in a hidden partition of the data card. The present invention makes attackers not perceive the existence of the information and increases the security of the information in the data card, so as to protect the user's private information better.
摘要翻译：本发明公开了一种基于数据卡保护信息的方法和装置，该方法包括：选择需要隐藏在终端设备中的信息; 并将需要隐藏的所述信息存储在数据卡的隐藏分区中。本发明使得攻击者不感知信息的存在并提高数据卡中的信息的安全性，从而更好地保护用户的私人信息。

5. 发明授权

US08822732B2 1,5-diphenyl-penta-1,4-dien-3-one compounds 有权
标题翻译： 1,5-二苯基 - 戊-1,4-二烯-3-酮化合物
公开(公告)号：US08822732B2
公开(公告)日：2014-09-02
申请号：US13210728
申请日：2011-08-16
申请人： Charles C-Y Shih , Toshio Kitamura , Qian Shi , Toshiyuki Kawashima , Hui-Kang Wang
发明人： Charles C-Y Shih , Toshio Kitamura , Qian Shi , Toshiyuki Kawashima , Hui-Kang Wang
IPC分类号： C07F15/00 , C07C49/00 , A61K31/12
CPC分类号： C07C49/248 , C07C49/235 , C07C49/255 , C07C69/16 , C07C217/22 , C07C217/60 , C07C235/82 , C07C307/02 , C07C309/65 , C07C309/66 , C07C309/73 , C07C317/24 , C07C2601/14 , C07C2601/16 , C07D213/68 , C07D295/112 , C07D295/13 , C07F9/06 , C07F9/09 , C07F9/12 , C07F9/32 , C07F9/3282
摘要： This invention relates to compounds of Formula (I), (II), or (III) as shown in the specification, which contain a 1,5-diphenylpenta-1,4-dien-3-one backbone. These compounds can be used to treat cancer, inflammatory disease, or autoimmune disease.
摘要翻译：本发明涉及说明书中所示的含有1,5-二苯基戊-1,4-二烯-3-酮骨架的式（I），（II）或（III）的化合物。这些化合物可用于治疗癌症，炎性疾病或自身免疫性疾病。

6. 发明申请

US20120204268A1 METHOD AND APPARATUS FOR PROTECTING INFORMATION BASED ON DATA CARD 有权
标题翻译：用于保护基于数据卡的信息的方法和装置
公开(公告)号：US20120204268A1
公开(公告)日：2012-08-09
申请号：US13259931
申请日：2010-05-21
申请人： Qian Shi
发明人： Qian Shi
IPC分类号： G06F21/24 , G06F12/14
CPC分类号： G06F21/31 , G06F21/79
摘要： The present invention discloses a method and apparatus for protecting information based on a data card, and the method comprises: selecting information which needs to be hidden in a terminal device; and storing said information which needs to be hidden in a hidden partition of the data card. The present invention makes attackers not perceive the existence of the information and increases the security of the information in the data card, so as to protect the user's private information better.
摘要翻译：本发明公开了一种基于数据卡保护信息的方法和装置，该方法包括：选择需要隐藏在终端设备中的信息; 并将需要隐藏的所述信息存储在数据卡的隐藏分区中。本发明使得攻击者不感知信息的存在并提高数据卡中的信息的安全性，从而更好地保护用户的私人信息。

7. 发明授权

US06265571B1 Purification process for anti-parasitic fermentation product 失效
标题翻译：抗寄生发酵产品的净化过程
公开(公告)号：US06265571B1
公开(公告)日：2001-07-24
申请号：US09351751
申请日：1999-07-12
申请人： Qian Shi , John A. Hill
发明人： Qian Shi , John A. Hill
IPC分类号： C07H100
CPC分类号： C07H17/08
摘要： A process for purifying the bacterial fermentation product ivermectin, particularly for use as a reference standard compound in a governmental regulatory approval process. The process includes the use of reversed-phase flash column chromatography coupled with gradient elution. An exemplary eluent mixture includes acetonitrile, methanol and water.
摘要翻译：纯化细菌发酵产物伊维菌素的方法，特别是在政府监管批准过程中用作参考标准化合物。该方法包括使用反相快速柱层析和梯度洗脱。示例性的洗脱剂混合物包括乙腈，甲醇和水。

8. 发明授权

US08236852B2 Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof 有权
公开(公告)号：US08236852B2
公开(公告)日：2012-08-07
申请号：US12008124
申请日：2008-01-08
申请人： Charles C. Y. Shih , Qian Shi , Hui-Kang Wang , Ching-Yuan Su
发明人： Charles C. Y. Shih , Qian Shi , Hui-Kang Wang , Ching-Yuan Su
IPC分类号： A61K31/24 , A61K31/135 , A61K31/12
CPC分类号： C07C49/255 , C07C45/00 , C07C45/30 , C07C45/673 , C07C45/68 , C07C45/73 , C07C45/74 , C07C47/277 , C07C49/248 , C07C49/753 , C07C69/007 , C07C69/738 , C07C69/96 , C07C225/16 , C07C2601/02 , C07C2601/04 , C07C2601/14 , C07C49/12
摘要： The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, acne, alopecia, hirsutism, a wound, prostate cancer, bladder cancer, liver cancer, breast cancer and Kennedy's disease.

9. 发明申请

US20120046247A1 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS 有权
标题翻译： 1,5-二苯基-1,4-二烯-3-酮化合物
公开(公告)号：US20120046247A1
公开(公告)日：2012-02-23
申请号：US13210728
申请日：2011-08-16
申请人： Charles C-Y Shih , Toshio Kitamura , Qian Shi , Toshiyuki Kawashima , Hui-Kang Wang
发明人： Charles C-Y Shih , Toshio Kitamura , Qian Shi , Toshiyuki Kawashima , Hui-Kang Wang
IPC分类号： A61K31/6615 , C07C309/67 , C07D211/74 , C07C235/82 , C07F9/12 , C07F9/32 , C07C225/16 , C07C49/255 , C07C307/02 , C07D295/112 , A61K31/12 , A61K31/255 , A61K31/45 , A61K31/165 , A61K31/663 , A61K31/138 , A61K31/661 , A61K31/4453 , A61K31/5375 , A61P35/00 , A61P35/02 , C07C49/248
CPC分类号： C07C49/248 , C07C49/235 , C07C49/255 , C07C69/16 , C07C217/22 , C07C217/60 , C07C235/82 , C07C307/02 , C07C309/65 , C07C309/66 , C07C309/73 , C07C317/24 , C07C2601/14 , C07C2601/16 , C07D213/68 , C07D295/112 , C07D295/13 , C07F9/06 , C07F9/09 , C07F9/12 , C07F9/32 , C07F9/3282
摘要： This invention relates to compounds of Formula (I), (II), or (III) as shown in the specification, which contain a 1,5-diphenylpenta-1,4-dien-3-one backbone. These compounds can be used to treat cancer, inflammatory disease, or autoimmune disease.
摘要翻译：本发明涉及说明书中所示的含有1,5-二苯基戊-1,4-二烯-3-酮骨架的式（I），（II）或（III）的化合物。这些化合物可用于治疗癌症，炎性疾病或自身免疫性疾病。

10. 发明申请

US20060145776A1 High-speed VCO calibration technique for frequency synthesizers 审中-公开
标题翻译：用于频率合成器的高速VCO校准技术
公开(公告)号：US20060145776A1
公开(公告)日：2006-07-06
申请号：US11028693
申请日：2005-01-05
申请人： Qian Shi , Kevin Wang
发明人： Qian Shi , Kevin Wang
IPC分类号： H03L1/00
CPC分类号： H03L7/10 , H03L7/0891 , H03L7/18
摘要： The voltage-controlled oscillator (VCO) in a frequency synthesizer using a phase-locked loop (PLL) is calibrated digitally during power up. The VCO has a coarse frequency control and a fine frequency control. The coarse control is a digital phase-locked loop to quantize the broad frequency range into limited number of frequency steps with a clock frequency divided from the VCO frequency, and to hold the phase-locked dc control voltage for the fine control. By limiting the number of frequency steps and clocking at a divided frequency of the VCO, the coarse control is speeded up. The fine control is [connected to the charge pump output as in] a regular PLL. By searching for the optimal control setting, the center frequency of the VCO is trimmed close to the wanted frequency for the PLL to lock. This allows small VCO gain without losing the tolerance of process and temperature variations. As a result, the PLL phase noise performance is improved.
摘要翻译：在上电期间，使用锁相环（PLL）的频率合成器中的压控振荡器（VCO）进行数字校准。 VCO具有粗略的频率控制和精细的频率控制。粗略控制是数字锁相环，用于将宽频率范围量化为有限数量的频率步长，时钟频率与VCO频率分开，并保持用于精细控制的锁相直流控制电压。通过限制VCO的分频频率的频率步长和时钟频率，粗调控制被加速。精细的控制是[连接到常规PLL的电荷泵输出]。通过搜索最佳控制设置，VCO的中心频率被修剪成接近PLL的锁定频率。这允许小的VCO增益，而不会失去工艺和温度变化的公差。结果，提高了PLL相位噪声性能。

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