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    • 2. 发明申请
    • NONCRYSTALLINE FORM OF FLUORENE DERIVATIVE AND PROCESS FOR PREPARATION THEREOF
    • 氟代衍生物的非晶形式及其制备方法
    • US20120095270A1
    • 2012-04-19
    • US13376516
    • 2010-06-01
    • Katsuhiro FujiiSuguru HataKohta Fukui
    • Katsuhiro FujiiSuguru HataKohta Fukui
    • C07C43/23
    • C07C41/40C07C43/23
    • An object of the present invention is to provide (i) a novel non-crystalline form of 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene, which non-crystalline form maintains quality at a certain level, and is excellent as a polymer material, and (ii) a method of preparing the non-crystalline form. According to the present invention, molten 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene in a liquid form is cooled and therefore is solidified. With the method, it is possible to provide a novel non-crystalline form of 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene which has a small risk that powder dust of 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene might cause explosion or a health problem. Further, the non-crystalline form of 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene can be adjusted arbitrarily in particle diameter by, for example, pulverizing the non-crystalline form in accordance with equipment or usage. In other words, the non-crystalline form of 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene is advantageous in handleability industrially.
    • 本发明的目的是提供(i)9,9-双(4-(2-羟基乙氧基)苯基)芴的新型非结晶形式,其非结晶形式在一定水平上保持质量,并且为 作为聚合物材料是优异的,和(ii)制备非结晶形式的方法。 根据本发明,将熔融的液体形式的9,9-双(4-(2-羟基乙氧基)苯基)芴冷却并因此固化。 通过该方法,可以提供9,9-双(4-(2-羟基乙氧基)苯基)芴的新型非结晶形式,其具有9,9-双(4-( 2-羟基乙氧基)苯基)芴可能引起爆炸或健康问题。 此外,9,9-双(4-(2-羟基乙氧基)苯基)芴的非结晶形式可以通过例如根据设备或用途粉碎非晶形来粒径任意调节。 换句话说,9,9-双(4-(2-羟基乙氧基)苯基)芴的非结晶形式在工业上有利于可操作性。
    • 8. 发明授权
    • Noncrystalline form of fluorene derivative and process for preparation thereof
    • 非晶形式的芴衍生物及其制备方法
    • US08436214B2
    • 2013-05-07
    • US13376516
    • 2010-06-01
    • Katsuhiro FujiiSuguru HataKohta Fukui
    • Katsuhiro FujiiSuguru HataKohta Fukui
    • C07C41/40C07C43/23
    • C07C41/40C07C43/23
    • An object of the present invention is to provide (i) a novel non-crystalline form of 9,9-bis(4-(2-hydroxyethoxy) phenyl) fluorene, which non-crystalline form maintains quality at a certain level, and is excellent as a polymer material, and (ii) a method of preparing the non-crystalline form. According to the present invention, molten 9,9-bis(4-(2-hydroxyethoxy) phenyl) fluorene in a liquid form is cooled and therefore is solidified. With the method, it is possible to provide a novel non-crystalline form of 9,9-bis(4-(2-hydroxyethoxy) phenyl) fluorene which has a small risk that powder dust of 9,9-bis(4-(2-hydroxyethoxy) phenyl) fluorine might cause explosion or a health problem. Further, the non-crystalline form of 9,9-bis(4-(2-hydroxyethoxy) phenyl) fluorene can be adjusted arbitrarily in particle diameter by, for example, pulverizing the non-crystalline form in accordance with equipment or usage. In other words, the non-crystalline form of 9,9-bis(4-(2-hydroxyethoxy) phenyl) fluorene is advantageous in handleability industrially.
    • 本发明的目的是提供(i)9,9-双(4-(2-羟基乙氧基)苯基)芴的新型非结晶形式,其非结晶形式在一定水平上保持质量,并且是 作为聚合物材料是优异的,和(ii)制备非结晶形式的方法。 根据本发明,将熔融的液体形式的9,9-双(4-(2-羟基乙氧基)苯基)芴冷却并因此固化。 通过该方法,可以提供9,9-双(4-(2-羟基乙氧基)苯基)芴的新型非结晶形式,其具有9,9-双(4-( 2-羟基乙氧基)苯基)氟可能引起爆炸或健康问题。 此外,9,9-双(4-(2-羟基乙氧基)苯基)芴的非结晶形式可以通过例如根据设备或用途粉碎非晶形来粒径任意调节。 换句话说,9,9-双(4-(2-羟基乙氧基)苯基)芴的非结晶形式在工业上有利于可操作性。