专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5693859A Process of producing intermediates for use in production of alkoxyiminoacetamides and intermediates to be used therein 失效
标题翻译：制备用于生产烷氧基亚氨基乙酰胺的中间体及其中使用的中间体的方法
公开(公告)号：US5693859A
公开(公告)日：1997-12-02
申请号：US578029
申请日：1995-12-26
申请人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Moriyasu Masui
发明人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Moriyasu Masui
IPC分类号： C07D215/12 , C07C51/58 , C07C59/84 , C07C59/88 , C07C59/90 , C07C227/02 , C07C229/42 , C07C231/02 , C07C233/56 , C07C235/72 , C07C235/78 , C07C237/20 , C07C249/08 , C07C319/12 , C07C319/20 , C07C323/62 , C07D215/20 , C07D215/36 , C07D239/26 , C07D239/34 , C07D239/38 , C07D239/42 , C07D261/08 , C07D261/10 , C07D261/12 , C07D261/14 , C07D263/32 , C07D263/36 , C07D263/46 , C07D263/48 , C07D263/56 , C07D263/58 , C07D277/62 , C07D303/38 , C07D413/04 , C07C233/05
CPC分类号： C07C59/84 , C07C231/02 , C07C249/08
摘要： There is disclosed a process of producing an .alpha.-ketamide as an intermediate for use in the production of various alkoxyiminoacetamide compounds which are useful as fungicides. Also disclosed is an intermediate to be used in this process.
摘要翻译：公开了一种制备用作生产可用作杀真菌剂的各种烷氧基亚氨基乙酰胺化合物的中间体的α-甲酰胺的方法。还公开了在该方法中使用的中间体。

2. 发明授权

US5442063A Process for producing (E)-alkoxyimino or hydroxyimino-acetamide compounds and intermediates therefor 失效
标题翻译：（E） - 烷氧基亚氨基或羟基亚氨基 - 乙酰胺化合物及其中间体的制备方法
公开(公告)号：US5442063A
公开(公告)日：1995-08-15
申请号：US144425
申请日：1993-11-02
申请人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Kuniyoshi Nishida
发明人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Kuniyoshi Nishida
IPC分类号： C07C43/225 , A01N37/50 , C07C20060101 , C07C249/06 , C07C249/12 , C07C251/48 , C07C251/60 , C07C255/37 , C07C255/38 , C07C255/62 , C07C255/64 , C07C317/48 , C07C323/57 , C07C323/63 , C07D213/64 , C07D401/08 , C07F7/02
CPC分类号： C07C249/12 , C07C249/06 , C07C255/38 , C07C255/64 , C07C43/225
摘要： The present invention relates to a process for producing (E)-alkoxyiminoacetamide compounds useful as agricultural fungicides and a process for producing (E)-hydroxyiminoacetamide compounds useful as intermediates for producing them. The present invention also relates to an industrial process for producing (E)-methoxyiminoacetamide compounds useful as agricultural fungicides. This process is advantageous in terms of the cost, safety and the like.
摘要翻译：本发明涉及可用作农业杀真菌剂的（E） - 烷氧基亚氨基乙酰胺化合物的制备方法和用于生产（E） - 羟基亚氨基乙酰胺化合物的方法。本发明还涉及用于生产用作农业杀真菌剂的（E） - 甲氧基亚氨基乙酰胺化合物的工业方法。该方法在成本，安全性等方面是有利的。

3. 发明授权

US5387714A Process of producing intermediates for use in production of alkoxyiminoacetamides and intermediates to be used therein 失效
标题翻译：制备用于生产烷氧基亚氨基乙酰胺的中间体及其中使用的中间体的方法
公开(公告)号：US5387714A
公开(公告)日：1995-02-07
申请号：US953884
申请日：1992-09-30
申请人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Moriyasu Masui
发明人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Moriyasu Masui
IPC分类号： C07D215/12 , C07C51/58 , C07C59/84 , C07C59/88 , C07C59/90 , C07C227/02 , C07C229/42 , C07C231/02 , C07C233/56 , C07C235/72 , C07C235/78 , C07C237/20 , C07C249/08 , C07C319/12 , C07C319/20 , C07C323/62 , C07D215/20 , C07D215/36 , C07D239/26 , C07D239/34 , C07D239/38 , C07D239/42 , C07D261/08 , C07D261/10 , C07D261/12 , C07D261/14 , C07D263/32 , C07D263/36 , C07D263/46 , C07D263/48 , C07D263/56 , C07D263/58 , C07D277/62 , C07D303/38 , C07D413/04 , C07C55/38 , C07C59/21
CPC分类号： C07C59/84 , C07C231/02 , C07C249/08
摘要： There is disclosed a process of producing an .alpha.-ketamide as an intermediate for use in the production of various alkoxyiminoacetamide compounds which are useful as fungicides. Also disclosed is an intermediate to be used in this process.
摘要翻译：公开了一种制备用作生产可用作杀真菌剂的各种烷氧基亚氨基乙酰胺化合物的中间体的α-甲酰胺的方法。还公开了在该方法中使用的中间体。

4. 发明授权

US5627284A Process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor 失效
标题翻译：（E） - 烷氧基亚氨基或羟基亚氨基乙酰胺化合物及其中间体的制备方法
公开(公告)号：US5627284A
公开(公告)日：1997-05-06
申请号：US433931
申请日：1995-05-02
申请人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Kuniyoshi Nishida
发明人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Kuniyoshi Nishida
IPC分类号： C07C41/16 , C07C43/225 , C07C249/06 , C07C249/12 , C07C255/37 , C07C255/38 , C07C255/64 , C07D213/64 , C07D213/62
CPC分类号： C07D213/64 , C07C249/06 , C07C249/12 , C07C255/37 , C07C255/38 , C07C255/64 , C07C41/16
摘要： The present invention relates to a process for producing (E)-alkoxyiminoacetamide compounds useful as agricultural fungicides and a process for producing (E)-hydroxyiminoacetamide compounds useful as intermediates for producing them. The present invention also relates to an industrial process for producing (E)-methoxyiminoacetamide compounds useful as agricultural fungicides. This process is advantageous in terms of the cost, safety and the like.
摘要翻译：本发明涉及可用作农业杀真菌剂的（E） - 烷氧基亚氨基乙酰胺化合物的制备方法和用于生产（E） - 羟基亚氨基乙酰胺化合物的方法。本发明还涉及用于生产用作农业杀真菌剂的（E） - 甲氧基亚氨基乙酰胺化合物的工业方法。该方法在成本，安全性等方面是有利的。

5. 发明授权

US5502252A Process of producing intermediates for use in production of alkoxyiminoacetamides and intermediates to be used therein 失效
公开(公告)号：US5502252A
公开(公告)日：1996-03-26
申请号：US339254
申请日：1994-11-10
申请人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Moriyasu Masui
发明人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Moriyasu Masui
IPC分类号： C07D215/12 , C07C51/58 , C07C59/84 , C07C59/88 , C07C59/90 , C07C227/02 , C07C229/42 , C07C231/02 , C07C233/56 , C07C235/72 , C07C235/78 , C07C237/20 , C07C249/08 , C07C319/12 , C07C319/20 , C07C323/62 , C07D215/20 , C07D215/36 , C07D239/26 , C07D239/34 , C07D239/38 , C07D239/42 , C07D261/08 , C07D261/10 , C07D261/12 , C07D261/14 , C07D263/32 , C07D263/36 , C07D263/46 , C07D263/48 , C07D263/56 , C07D263/58 , C07D277/62 , C07D303/38 , C07D413/04 , C07C233/05
CPC分类号： C07C59/84 , C07C231/02 , C07C249/08
摘要： There is disclosed a process of producing an .alpha.-ketamide as an intermediate for use in the production of various alkoxyiminoacetamide compounds which are useful as fungicides. Also disclosed is an intermediate to be used in this process.

6. 发明授权

US5510506A Process for producing carboxylic acid derivatives 失效
标题翻译：制备羧酸衍生物的方法
公开(公告)号：US5510506A
公开(公告)日：1996-04-23
申请号：US392852
申请日：1995-03-27
申请人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Katuhisa Masumoto , Akihiko Nakamura , Yujiro Kiyoshima , Mikio Sasaki
发明人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Katuhisa Masumoto , Akihiko Nakamura , Yujiro Kiyoshima , Mikio Sasaki
IPC分类号： C07C249/12 , C07C251/48 , C07C229/02
CPC分类号： C07C249/12 , C07C251/48
摘要： A process is disclosed to produce a carboxylic acid derivative of the general formula VIII!: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and L are each as defined in the specification, characterized in that a benzyl halide is reacted with a cyano compound to give a phenylacetonitrile, which is then reacted with an alkyl nitrite in the presence of a base to give an .alpha.-hydroxyiminophenylacetonitrile, which is then reacted with an alkylating agent to give an .alpha.-alkoxyiminophenylacetonitrile, which is then hydrolyzed in the presence of a base, or is hydrated and treated with an acid, followed by hydrolysis in the presence of a base, to give an .alpha.-alkoxyiminophenylacetic acid, which is then reacted with an acid halide forming agent, or is convened into a metal salt, followed by reaction with an alkylating agent, or is reacted with a lower alcohol in the presence of an acid catalyst.According to the present invention, the reactions can be allowed to proceed under mild conditions over the whole process, and the desired carboxylic acid derivative VIII! can be produced without any facilities such as high-pressure steam equipment, high-temperature heat medium control equipment and freezing machines. In addition, there is no need to use various different solvents in the respective steps and the present process can be conducted with only one solvent, in which respect the present invention is also advantageous.
摘要翻译： PCT No.PCT / JP94 / 01075 Sec。 371日期：1995年3月27日 102（e）1995年3月27日PCT PCT 1994年7月1日PCT公布。出版物WO95 / 01328 日本公开1995年1月12日。公开了一种制备通式[Ⅷ]羧酸衍生物的方法：各自如说明书中所定义，其特征在于苄基卤与氰基化合物反应得到苯乙腈然后在碱的存在下与亚硝酸烷基酯反应，得到α-羟基亚氨基苯基乙腈，然后与烷基化剂反应，得到α-烷氧基亚氨基苯基乙腈，然后在碱的存在下水解，或水合和然后在碱的存在下水解，得到α-烷氧基亚氨基苯基乙酸，然后与酰卤化物形成试剂反应，或转入金属盐中，随后与烷基化剂反应，或者在酸催化剂的存在下与低级醇反应。根据本发明，可以在整个过程的温和条件下进行反应，并且可以制备所需的羧酸衍生物[Ⅷ]，无需任何设备，例如高压蒸汽设备，高温热介质控制设备和冷冻机。此外，在各步骤中不需要使用各种不同的溶剂，并且本发明方法可以仅使用一种溶剂进行，其中本发明也是有利的。

7. 发明授权

US5629442A Process for producing .alpha.-hydroxyiminophenylacetonitriles 失效
标题翻译：制备α-羟基亚氨基苯基乙腈的方法
公开(公告)号：US5629442A
公开(公告)日：1997-05-13
申请号：US392860
申请日：1995-05-11
申请人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Katuhisa Masumoto , Akihiko Nakamura , Yujiro Kiyoshima , Mikio Sasaki
发明人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Katuhisa Masumoto , Akihiko Nakamura , Yujiro Kiyoshima , Mikio Sasaki
IPC分类号： C07C251/48 , C07C253/14 , C07C253/30 , C07C255/64 , C07C255/01
CPC分类号： C07C251/48 , C07C253/14 , C07C253/30 , C07C255/64
摘要： A process is disclosed to produce an .alpha.-hydroxyiminophenylacetonitrile of the general formula [II]: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and Z are each as defined in the specification, characterized in that a crude nitrile containing a phenylacetonitrile of the general formula [I]: ##STR2## wherein R.sup.1, R.sup.2, R.sup.3 and Z are each as defined in the specification, is reacted with an alkyl nitrite in the presence of a base, after which the reaction mixture is extracted with water and then the separated aqueous layer is neutralized with an acid. According to this production process, the desired .alpha.-hydroxyiminophenylacetonitrile can be produced with high purity, in high yield and with ease by extracting the reaction mass with water and then neutralizing the separated aqueous layer with an acid.
摘要翻译： PCT No.PCT / JP94 / 01076 Sec。 371日期1995年5月11日 102（e）日期1995年5月11日PCT提交1993年7月2日PCT公布。公开号WO95 / 01329 日期1995年1月12日公开了制备通式[II]的α-羟基亚氨基苯基乙腈的方法：其中R 1，R 2，R 3和Z各自如说明书中所定义，其特征在于，含有通式[I]的苯基乙腈的腈：其中R 1，R 2，R 3和Z各自如本说明书中所定义，其中R 1，R 2，R 3和Z各自在碱存在下与亚硝酸烷基酯反应，之后，反应混合物用水萃取，然后用酸中和分离的水层。根据该制造方法，可以通过用水提取反应物质，然后用酸中和分离的水层，以高产率和容易地制备所需的α-羟基亚氨基苯基乙腈。

8. 发明授权

US5506358A Process for producing alkoxyiminoacetamide compounds 失效
标题翻译：制备烷氧基亚氨基乙酰胺化合物的方法
公开(公告)号：US5506358A
公开(公告)日：1996-04-09
申请号：US207055
申请日：1994-03-08
申请人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Kazuo Ueda , Tsuneo Iwakawa
发明人： Akira Takase , Hiroyuki Kai , Moriyasu Masui , Kazuo Ueda , Tsuneo Iwakawa
IPC分类号： C07D215/22 , C07C249/12 , C07C251/48 , C07C255/62 , C07C317/48 , C07C323/60 , C07C323/63 , C07D213/65 , C07D277/68 , C07D303/46 , C07D307/42 , C07D309/12 , C07D239/02 , C07C249/04
CPC分类号： C07D213/65 , C07C249/12 , C07C251/48
摘要： There is disclosed a process for producing an alkoxyiminoacetamide compound which is useful as agricultural fungicides. Also dislclosed are novel intermediate compounds for the above process and their production.
摘要翻译：公开了可用作农业杀真菌剂的烷氧基亚氨基乙酰胺化合物的制备方法。也可以是上述方法的新型中间体化合物及其制备。

9. 发明授权

US5488159A Process for producing methoxyiminoacetamide compounds and intermediates 失效
标题翻译：制备甲氧基亚氨基乙酰胺化合物和中间体的方法
公开(公告)号：US5488159A
公开(公告)日：1996-01-30
申请号：US295458
申请日：1994-08-25
申请人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Shoji Shinomoto , Masahiko Nagai
发明人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Shoji Shinomoto , Masahiko Nagai
IPC分类号： C07C249/12 , C07C251/48 , C07C255/64 , C07C239/20
CPC分类号： C07C251/48 , C07C249/12 , C07C255/64
摘要： A compound of the formula [I]: ##STR1## wherein X is hydrogen, lower alkyl, lower alkoxy or halogen; .about. is any configuration of E-isomer, Z-isomer or a mixture thereof is produced by reacting a compound of the formula [II] ##STR2## wherein X and .about. are as defined above; W is --CN or --COOR; and R is a lower alkyl, with methylamine in the presence of methanol. The compound [I] is useful for an agricultural fungicide. An intermediate used for producing the compound [I] is also disclosed.
摘要翻译：式[I]的化合物：其中X是氢，低级烷基，低级烷氧基或卤素; 差异是E-异构体，Z-异构体或其混合物的任何构型是通过使式[II]化合物[II]化合物或其混合物与其中X和DIFFERENCE如上定义反应而制备的。 W是-CN或-COOR; 在甲醇存在下，R为低级烷基，甲胺。化合物[I]可用于农药杀菌剂。还公开了用于制备化合物[I]的中间体。

10. 发明授权

US06268312B1 Oxime derivative and bactericide containing the same as active ingredient 失效
标题翻译：含有与活性成分相同的肟衍生物和杀菌剂
公开(公告)号：US06268312B1
公开(公告)日：2001-07-31
申请号：US09370255
申请日：1999-08-09
申请人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Tsuneo Iwakawa , Kazuo Ueda , Michio Masuko
发明人： Akira Takase , Hiroyuki Kai , Kuniyoshi Nishida , Tsuneo Iwakawa , Kazuo Ueda , Michio Masuko
IPC分类号： A01N4348
CPC分类号： C07D231/06 , A01N43/50 , C07D231/12 , C07D233/64 , C07D249/08 , C07D257/04 , C07D261/08 , C07D263/10 , C07D263/32 , C07D271/06 , C07D271/10 , C07D277/10 , C07D285/06
摘要： A compound represented by general formula (I) or a salt thereof, a process for producing the same, an intermediate for the production thereof, and a bactericide (fungicide) containing the same as the active ingredient wherein R1 represent optionally substituted aryl, optionally substituted heterocycle, mono- or di-substituted methyleneamino, optionally substituted (substituted imino)methyl, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, substituted carbonyl or substituted sulfonyl; R2 represents alkyl, alkenyl, alkynyl or cycloalkyl; R3 represents optionally substituted heterocycle; R4 represents hydrogen, alkyl, alkoxy, halogen, nitro, cyano or haloalkyl; M represents oxygen, S(O)i (i being 0, 1 or 2), NR16 (R16 being hydrogen, alkyl or acyl) or a single bond; n represents 0 or 1, provided n represent 1 when R3 represents imidazol-1-yl or 1H-1,2,4-triazol-1-yl; and the symbol˜represents the E form, Z form or a mixture thereof.
摘要翻译：由通式（I）表示的化合物或其盐，其制备方法，其制备中间体和含有该活性成分的杀菌剂（杀真菌剂），其中R 1表示任选取代的芳基，任选取代的取代的亚氨基甲基，任选取代的烷基，任选取代的烯基，任选取代的炔基，取代的羰基或取代的磺酰基; R2代表烷基，烯基，炔基或环烷基; R3表示任选取代的杂环; R4代表氢，烷基，烷氧基，卤素，硝基，氰基或卤代烷基; M表示氧，S（O）i（i为0,1或2），NR 16（R 16为氢，烷基或酰基）或单键; 当R 3表示咪唑-1-基或1H-1,2,4-三唑-1-基时，n表示0或1，条件是n表示1。符号〜表示E形式，Z形式或其混合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式