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1. 发明申请

US20060170925A1 Biomolecular sensor system utilizing a transverse propagation wave of surface plasmon Resonance (SPR) 有权
标题翻译：利用表面等离振子共振（SPR）的横向传播波的生物分子传感器系统
公开(公告)号：US20060170925A1
公开(公告)日：2006-08-03
申请号：US11049085
申请日：2005-02-02
申请人： Chii-Wann Lin , Chih Kung Lee , Zhi-Hsiang Sung , Shiming Lin
发明人： Chii-Wann Lin , Chih Kung Lee , Zhi-Hsiang Sung , Shiming Lin
IPC分类号： G01N21/55
CPC分类号： G01N21/553
摘要： A biomolecular sensor system utilizing a transverse propagation wave of surface plasmon resonance (SPR) is described. The system comprises: a substrate; a dielectric layer, having a groove therein and standing on top of the substrate; a sensing film layer, sitting at the groove; a pair of prism devices, each resting on one side of the groove and both separating a tunable distance. Besides, the sensor system further comprises a light source, a light detector (a frontend of which connecting to a spectrometer and a backend connecting to a differential amplifier) and a channel with a cover forming inside the groove for the acquisition of the reflected light from the prism devices. Since the sensor system is constructed by exploiting the SPR technique on the transverse propagation, a whole contact surface is under detection (parallel detection) which differentiates it from the traditional method of single-area SPR detection. The sensor system is applicable not only for the far-infrared remote sensing with a transverse distance of several centimeters, but further for the biomedical sensing applications in the miniature sizing and high throughput.
摘要翻译：描述了利用表面等离子体共振（SPR）的横向传播波的生物分子传感器系统。该系统包括：基板; 介电层，其中具有凹槽并站立在所述基板的顶部上; 位于凹槽处的感测膜层; 一对棱镜装置，每个棱镜装置分别搁置在凹槽的一侧并且两者分离可调距离。此外，传感器系统还包括光源，光检测器（其前端连接到光谱仪和连接到差分放大器的后端）以及形成在凹槽内的盖的通道，用于获取反射光的反射光棱镜装置。由于传感器系统是通过利用SPR技术在横向传播中构建的，因此整个接触面被检测（并行检测），与传统的单区域SPR检测方法相区分。传感器系统不仅适用于横向距离为几厘米的远红外遥感，而且适用于微型尺寸和高通量的生物医学传感应用。

2. 发明授权

US07271914B2 Biomolecular sensor system utilizing a transverse propagation wave of surface plasmon resonance (SPR) 有权
标题翻译：利用表面等离子体共振（SPR）的横向传播波的生物分子传感器系统
公开(公告)号：US07271914B2
公开(公告)日：2007-09-18
申请号：US11049085
申请日：2005-02-02
申请人： Chii-Wann Lin , Chih Kung Lee , Zhi-Hsiang Sung , Shiming Lin
发明人： Chii-Wann Lin , Chih Kung Lee , Zhi-Hsiang Sung , Shiming Lin
IPC分类号： G01N21/55
CPC分类号： G01N21/553
摘要： A biomolecular sensor system utilizing a transverse propagation wave of surface plasmon resonance (SPR) is described. The system comprises: a substrate; a dielectric layer, having a groove therein and standing on top of the substrate; a sensing film layer, sitting at the groove; a pair of prism devices, each resting on one side of the groove and both separating a tunable distance. Besides, the sensor system further comprises a light source, a light detector (a frontend of which connecting to a spectrometer and a backend connecting to a differential amplifier) and a channel with a cover forming inside the groove for the acquisition of the reflected light from the prism devices. Since the sensor system is constructed by exploiting the SPR technique on the transverse propagation, a whole contact surface is under detection (parallel detection) which differentiates it from the traditional method of single-area SPR detection. The sensor system is applicable not only for the far-infrared remote sensing with a transverse distance of several centimeters, but further for the biomedical sensing applications in the miniature sizing and high throughput.
摘要翻译：描述了利用表面等离子体共振（SPR）的横向传播波的生物分子传感器系统。该系统包括：基板; 介电层，其中具有凹槽并站立在所述基板的顶部上; 位于凹槽处的感测膜层; 一对棱镜装置，每个棱镜装置分别搁置在凹槽的一侧并且两者分离可调距离。此外，传感器系统还包括光源，光检测器（其前端连接到光谱仪和连接到差分放大器的后端）以及形成在凹槽内的盖的通道，用于获取反射光的反射光棱镜装置。由于传感器系统是通过利用SPR技术在横向传播中构建的，因此整个接触面被检测（并行检测），与传统的单区域SPR检测方法相区分。传感器系统不仅适用于横向距离为几厘米的远红外遥感，而且适用于微型尺寸和高通量的生物医学传感应用。

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