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1. 发明授权

US5948654A Magnetically oriented tissue-equivalent and biopolymer tubes comprising collagen 失效
标题翻译：包含胶原的磁性取向组织等效物和生物聚合物管
公开(公告)号：US5948654A
公开(公告)日：1999-09-07
申请号：US70392896
申请日：1996-08-28
申请人： UNIV MINNESOTA
发明人： TRANQUILLO ROBERT T , MOORADIAN DANIEL L , GIRTON TIMOTHY S , GUIDO STEFANO
CPC分类号： A61L27/507 , A61L27/24 , A61L27/3826

2. 植物专利

US8488P Canker-resistant aspen tree 70-144-30-68-1 失效
标题翻译：耐克林白杨树70-144-30-68-1
公开(公告)号：US8488P
公开(公告)日：1993-12-07
申请号：US67550291
申请日：1991-03-25
申请人： UNIV MINNESOTA
发明人： ANDERSON NEIL A , OSTRY MICHAEL E
IPC分类号： A01H5/00
CPC分类号： A01H5/00
摘要： An aspen tree having rapid growth, good form, aesthetic appearance, and resistance to Hypoxylon canker caused by the fungus Hypoxylon mammatum.
摘要翻译：白桦树具有快速生长，良好的形态，美学外观，以及由真菌Hypoxylon mammatum引起的Hypoxylon罐头的抗性。

3. 发明授权

US5009956A Phospholipase A2-resistant liposomes 失效
标题翻译：磷脂酶A2抗性脂质体
公开(公告)号：US5009956A
公开(公告)日：1991-04-23
申请号：US33382989
申请日：1989-03-31
申请人： UNIV MINNESOTA
发明人： BAUMANN WOLFGANG J
IPC分类号： A61K9/127 , A61K9/133
CPC分类号： A61K9/127 , Y10S436/829 , Y10T428/2984
摘要： A method to inhibit phospholipase A2-type hydrolytic degradation of liposome membranes is disclosed comprising forming a liposome having a bilayer membrane comprising (i) between about 67.5-85 mol-% of a phospholipid of the formula: and (ii) between about 15.0-32.5 mol-% of a lysophospholipid of the formula: wherein R1, R2 and R3 are individually (C10-C30) alkanoyl groups including from about 0-4 double bonds.
摘要翻译：公开了抑制脂质体膜的磷脂酶A2型水解降解的方法，其包括形成具有双层膜的脂质体，所述双层膜包含（i）约67.5-85摩尔％的下式的磷脂：和（ii）约15.0-32.5mol％的下式的溶血磷脂：其中R1，R2和R3分别是包括约0-4个双键的（C 10 -C 30）烷酰基。

4. 植物专利

US4327P Chrysanthemum named Minngopher 失效
标题翻译：菊花命名为Minngopher
公开(公告)号：US4327P
公开(公告)日：1978-10-31
申请号：US79749677
申请日：1977-05-16
申请人： UNIV MINNESOTA
发明人： WIDMER RICHARD E
IPC分类号： A01H5/00
摘要： {PG,1 A new and distinct cultivar of chrysanthemum of the outdoor garden and greenhouse pot plant type characterized by its dark red, medium sized blooms of decorative flower form which appear in an open spray formation, its ability to be flowered the year around with uniform 6-week response under photoperiod control, and by its excellent performance as a spring, summer and fall potted plant and as a natural season garden flower.
摘要翻译： {PG，1一种新鲜独特的户外花园和温室盆栽植物菊花品种，其特征在于其深红色，中等大小的装饰花朵绽放，以露天喷雾形式出现，其年度开花能力在光周期控制下制服6周响应，并以其优异的性能作为春季，夏季和秋季盆栽植物和作为自然季花园花。

5. 发明授权

US3920808A Method of protecting human skin from actinic radiation 失效
标题翻译：保护人体皮肤免受紫外线辐射的方法
公开(公告)号：US3920808A
公开(公告)日：1975-11-18
申请号：US35838473
申请日：1973-05-08
申请人： UNIV MINNESOTA
发明人： FUSARO RAMON M
IPC分类号： A61K8/35 , A61Q17/04 , A61Q19/04 , A61L23/00
CPC分类号： A61Q19/04 , A61K8/35 , A61K8/355 , A61K2800/884 , A61Q17/04
摘要： Enhanced protection from sunlight is achieved by applying to human skin beforehand separate, time-spaced applications of (1) a carbonyl compound which is reactive with amino groups in human skin, for example dihydroxyacetone, and (2) a benzo- or napthoquinone such as lawsone. Preferably several sequential applications of each active component in a separate carrier are made the evening before the first exposure, and protection is thereafter maintained by applying each component separately each evening.

6. 发明授权

US3825541A (+-)-9-(beta-(3-alpha-amino-2alpha-hydroxy)cyclopentyl)-6-substituted-purines and derivatives thereof 失效
标题翻译：（±）-9-（BETA-（3-ALPHA-AMINO-2ALPHA-羟基）环戊基）-6-取代的脯氨酸及其衍生物
公开(公告)号：US3825541A
公开(公告)日：1974-07-23
申请号：US22089072
申请日：1972-01-26
申请人： UNIV MINNESOTA
发明人： VINCE R
IPC分类号： C07D317/72 , C07D473/00 , C07D57/38
CPC分类号： C07D317/72 , C07D473/00
摘要： A NEW CLASS OF CHEMICAL COMPOUNDS, ($)-9-(B(3AAMINO-2A-HYDROXY)CYCLOPENTYL) - 6 - SUBSTITUTED - PURINES HAVING THE GENERAL FORMULA:

6-R,9-(2-(HO-),3-X-CYCLOPENTYL)-9H-PURINE

WHEREIN R IS A SUBSTITUENT SELECTED FROM THE GROUP CONSISTING OF HYDROXYL, MERCAPTO, METHYL MERCAPTO, HALOGEN (CHLORINE, BROMINE, FLUORINE AND IODINE) AND SUBSTITUTED AMONO:

R''-N(-R")-

WHEREIN R'' AND R'''' MAY BE THE SAME OR DIFFERENT SUBSTITUENTS AND ARE SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, METHYL, ETHYL, PROPYL AND PHENYL; X IS AN AMINO RADICALOR AMINO ACID; AND ACID SALT DERIVATIVES OF THE SAME, SUCH AS ACETIC, HYDROCHLORIC, SULFURIC, ETC.; AND THE METHOD OF PREPARATION THEREOF. THE INTERMEDIATE ($)-9(B-(3A-AMINO - 2A - HYDROXY)CYCLOPENTYL) - 6 - DIMETHYLAMINOPURINE, OR ANY OF ITS CORRESPONDING 6-SUBSTITUTED DERIVATIVES, LEADS TO THE PREPARATION OF TWO DIASTERIOISOMERS WHEN CONDENSED WITH THE APPROPRIATELY BLOCKED LAMINO ACID. THE SEPARATION OF THESE DIASTERIOISOMERS RESULTS IN THE ISOLATION OF ANTIMICROBIAL AND ANTITUMOR AGENTS.

7. 发明授权

US3760812A Implantable spiral wound stimulation electrodes 失效
标题翻译：可植入螺旋形刺激电极
公开(公告)号：US3760812A
公开(公告)日：1973-09-25
申请号：US3760812D
申请日：1971-03-19
申请人： UNIV MINNESOTA
发明人： TIMM G , BRADLEY W
IPC分类号： A61N1/05 , A61N1/04
CPC分类号： A61N1/05
摘要： Electrical stimulation electrodes for implantation within a living body for transmission of stimuli to excitable neural or contractile cells. The electrodes are characterized by flexibility to permit following of contour variations and maintenance of electrical contact with the stimulation region. The electrodes include a pair of parallel spaced apart helically wound conductors maintained in this configuration. When the electrode is implanted, undesired excitation of nearby structures can be avoided.
摘要翻译：用于植入生物体内用于将刺激传递至可兴奋的神经或收缩细胞的电刺激电极。电极的特征在于灵活性，允许跟随轮廓变化和维持与刺激区域的电接触。电极包括保持在该构造中的一对平行隔开的螺旋缠绕导体。当植入电极时，可避免附近结构的不期望的激发。

8. 发明授权

US3731681A Implantable indusion pump 失效
标题翻译：可植入式泵
公开(公告)号：US3731681A
公开(公告)日：1973-05-08
申请号：US3731681D
申请日：1972-01-14
申请人： UNIV MINNESOTA
发明人： BLACKSHEAR P , DORMAN F , BLACKSHEAR P L , BUCHWALD H , VARCO R
IPC分类号： A61M5/14 , A61M5/142 , A61M5/00
CPC分类号： A61M5/14276 , A61M5/141 , A61M5/16877
摘要： An implantable pump for infusing drugs or other chemicals or solutions into the body at a uniform slow flow rate. The pump comprises a housing divided into two chambers separated by a bellows, diaphragm or other pressure-communicating interphase. A volatile liquid partially filling one chamber provides 9 constant pressure energy source to act upon the interphase to force liquid infusate from the other chamber through a capillary tube or other flow-regulating resistance element to the infusion site. The infusate chamber is closed as by means of a self puncture sealing refill stopper. The pump is implanted with the refill stopper disposed under the skin and the pump is refilled periodically by injection through the skin.
摘要翻译：一种植入式泵，用于以均匀的缓慢流速将药物或其他化学物质或溶液注入体内。泵包括被分隔成由波纹管，隔膜或其它压力连通的相间隔开的两个室的壳体。部分填充一个室的挥发性液体提供9个恒压能量源作用于间期，以迫使来自另一室的液体通过毛细管或其它流动调节电阻元件输送到输注部位。灌注腔通过自动穿刺密封填充塞子封闭。植入泵内设置在皮肤下方的补充塞子，并通过皮肤注射定期重新填充泵。

9. 发明授权

US3672579A Process for beneficiating magnetite iron ore 失效
标题翻译：获益于铁矿石的方法
公开(公告)号：US3672579A
公开(公告)日：1972-06-27
申请号：US3672579D
申请日：1970-08-10
申请人： UNIV MINNESOTA
发明人： LAWVER JAMES E
IPC分类号： B03C1/005 , C01G49/08 , B02C21/00
CPC分类号： C01G49/08 , B03C1/005 , C01P2004/61
摘要： A process for upgrading low-grade magnetite-containing iron ore with minimum fine grinding. The dry ore is first comminuted to between about three-fourths inch and 10 mesh particle size and magnetically separated. The dry tailing is discarded and the concentrate is ground to between about 20 and 100 mesh and again subjected to dry magnetic separation. The dry tailing is again discarded and the concentrate is then finely ground according to conventional practice and subjected to wet magnetic separation. About 90 percent or more of the tailing is discarded dry without fine grinding, permitting easy disposal without possible ecological damage due to lake and stream pollution.
摘要翻译：一种用最小细磨削升级含低铁含铁矿石的方法。干矿石首先粉碎至约四分之三英寸至十目粒度，并进行磁力分离。将干燥的拖尾丢弃，将浓缩物研磨至约20至100目之间，并再次进行干磁分离。再次将干燥的拖尾丢弃，然后根据常规实践将浓缩物精细研磨并进行湿式磁力分离。大约90％以上的拖尾被丢弃干燥而没有细磨，容易处理，不会因湖泊和河流污染而造成生态破坏。

10. 发明授权

US3646940A Implantable electronic stimulator electrode and method 失效
标题翻译：可植入电子刺激电极及方法
公开(公告)号：US3646940A
公开(公告)日：1972-03-07
申请号：US3646940D
申请日：1969-07-15
申请人： UNIV MINNESOTA
发明人： TIMM GERALD W , BRADLEY WILLIAM E
IPC分类号： A61N1/36
CPC分类号： A61N1/36007
摘要： An apparatus for implantation in the body to locally stimulate a mass of electrically excitable tissue without stimulating nearby tissue structures, and the method of so stimulating the tissue is described. The apparatus includes a plurality of electrodes, each of the electrodes including a pair of conductors for carrying signals of positive and negative polarity, each of said conductors having a plurality of electrically conductive coupling points for coupling to the mass of tissue. Apparatus is also described for providing timed sequenced electrical impulses to the plurality of electrodes so that only one of the electrodes has a voltage applied between its input terminals at any given time. An insulating backing placed between the electrodes and tissue structures surrounding the implanted stimulator for eliminating undesirable secondary tissue stimulation is also described. The method of applying controlled time-spaced electrical impulses to a mass of electrically excitable tissue structure for causing stimulation of that tissue structure is also described.
摘要翻译：描述了用于植入体内以局部刺激大量电可激发组织而不刺激附近组织结构的装置，以及刺激组织的方法。该装置包括多个电极，每个电极包括用于传送正极性和负极性信号的一对导体，每个所述导体具有用于耦合到组织块的多个导电耦合点。还描述了用于向多个电极提供定时排序的电脉冲的设备，使得在任何给定时间只有一个电极在其输入端子之间施加电压。还描述了放置在电极之间的绝缘背衬和围绕植入的刺激器的组织结构，用于消除不期望的次要组织刺激。还描述了将受控的时间间隔电脉冲施加到大量可电激发组织结构以引起该组织结构的刺激的方法。

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