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1. 发明授权

US08682410B2 Multi-array monophasic action potential medical device 有权
标题翻译：多阵列单相动作电位医疗器械
公开(公告)号：US08682410B2
公开(公告)日：2014-03-25
申请号：US13044698
申请日：2011-03-10
申请人： Randell L. Werneth , Meleze Hocini , Mark T. Stewart , Dan Wittenberger , Timothy J. Corvi , Michael Lau , Vinod Sharma
发明人： Randell L. Werneth , Meleze Hocini , Mark T. Stewart , Dan Wittenberger , Timothy J. Corvi , Michael Lau , Vinod Sharma
IPC分类号： A61B5/042 , A61B18/14
CPC分类号： A61B5/0422 , A61B18/1492 , A61B2018/1467 , A61B2018/1472 , A61B2218/002
摘要： A medical device including a catheter having a shaft with a distal portion; a first plurality of substantially hemispherical electrodes coupled to the distal portion; a second plurality of substantially hemispherical electrodes coupled to the shaft proximal of the first plurality, where the second plurality of electrodes are oriented substantially orthogonal to the first plurality of electrodes; and an additional electrode coupled to the shaft. A console may have a processor in electrical communication with the first and second plurality of electrodes and the reference electrode, the processor programmed to obtaining a monophasic action potential recording from at least one of the first and second plurality of electrodes.
摘要翻译：一种医疗装置，包括具有远端部的轴的导管; 耦合到所述远端部分的第一多个基本上半球形的电极; 耦合到所述第一多个的所述轴近端的第二多个基本上半球形的电极，其中所述第二多个电极定向成基本上垂直于所述第一多个电极; 以及连接到所述轴的附加电极。控制台可以具有与第一和第二多个电极和参考电极电连通的处理器，该处理器被编程为从第一和第二多个电极中的至少一个获得单相动作电位记录。

2. 发明申请

US20120232374A1 MULTI-ARRAY MONOPHASIC ACTION POTENTIAL MEDICAL DEVICE 有权
标题翻译：多阵列单因素行动潜能医疗器械
公开(公告)号：US20120232374A1
公开(公告)日：2012-09-13
申请号：US13044698
申请日：2011-03-10
申请人： Randell L. WERNETH , Meleze HOCINI , Mark T. STEWART , Dan WITTENBERGER , Timothy J. CORVI , Michael LAU , Vinod SHARMA
发明人： Randell L. WERNETH , Meleze HOCINI , Mark T. STEWART , Dan WITTENBERGER , Timothy J. CORVI , Michael LAU , Vinod SHARMA
IPC分类号： A61B5/04 , A61N1/05
CPC分类号： A61B5/0422 , A61B18/1492 , A61B2018/1467 , A61B2018/1472 , A61B2218/002
摘要： A medical device including a catheter having a shaft with a distal portion; a first plurality of substantially hemispherical electrodes coupled to the distal portion; a second plurality of substantially hemispherical electrodes coupled to the shaft proximal of the first plurality, where the second plurality of electrodes are oriented substantially orthogonal to the first plurality of electrodes; and an additional electrode coupled to the shaft. A console may have a processor in electrical communication with the first and second plurality of electrodes and the reference electrode, the processor programmed to obtaining a monophasic action potential recording from at least one of the first and second plurality of electrodes.
摘要翻译：一种医疗装置，包括具有远端部的轴的导管; 耦合到所述远端部分的第一多个基本上半球形的电极; 耦合到所述第一多个的所述轴近端的第二多个基本上半球形的电极，其中所述第二多个电极定向成基本上垂直于所述第一多个电极; 以及连接到所述轴的附加电极。控制台可以具有与第一和第二多个电极和参考电极电连通的处理器，该处理器被编程为从第一和第二多个电极中的至少一个获得单相动作电位记录。

3. 发明授权

US09532828B2 System and method for adaptive RF ablation 有权
标题翻译：自适应射频消融的系统和方法
公开(公告)号：US09532828B2
公开(公告)日：2017-01-03
申请号：US13096236
申请日：2011-04-28
申请人： Catherine R. Condie , Marshall L. Sherman , Kathryn E. Kasischke , Timothy J. Corvi , Aaron R. Strunk
发明人： Catherine R. Condie , Marshall L. Sherman , Kathryn E. Kasischke , Timothy J. Corvi , Aaron R. Strunk
IPC分类号： A61B18/18 , A61B18/14 , A61B18/12 , A61B18/00
CPC分类号： A61B18/14 , A61B18/1206 , A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00351 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00678 , A61B2018/00702 , A61B2018/00714 , A61B2018/00726 , A61B2018/00779 , A61B2018/00791 , A61B2090/065
摘要： A medical method, device, and system are provided, including advancing an ablation element of a medical device into contact with tissue to be treated, selecting a power level of energy to ablate the tissue, delivering energy at the selected power level to the ablation element, determining whether the ablation element is in continuous contact with the tissue, and reducing the selected power level when the ablation element ceases to be in continuous contact with the tissue.
摘要翻译：提供了一种医疗方法，装置和系统，包括使医疗装置的消融元件与待治疗组织接触，选择能量消耗组织的能量水平，将所选功率水平的能量输送到消融元件确定消融元件是否与组织连续接触，以及当消融元件停止与组织连续接触时降低所选择的功率水平。

4. 发明授权

US09504518B2 System and method for adaptive RF ablation 有权
标题翻译：自适应射频消融的系统和方法
公开(公告)号：US09504518B2
公开(公告)日：2016-11-29
申请号：US13096255
申请日：2011-04-28
申请人： Catherine R. Condie , Marshall L. Sherman , Kathryn E. Kasischke , Timothy J. Corvi , Aaron R. Strunk
发明人： Catherine R. Condie , Marshall L. Sherman , Kathryn E. Kasischke , Timothy J. Corvi , Aaron R. Strunk
IPC分类号： A61B18/18 , A61B18/14 , A61B18/12 , A61B18/00
CPC分类号： A61B18/14 , A61B18/1206 , A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00351 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00678 , A61B2018/00702 , A61B2018/00714 , A61B2018/00726 , A61B2018/00779 , A61B2018/00791 , A61B2090/065
摘要： A medical method, device, and system are provided, including advancing an ablation element of a medical device into contact with tissue to be treated, selecting a power level of energy to ablate the tissue, delivering energy at the selected power level to the ablation element, determining whether the ablation element is in continuous contact with the tissue, and reducing the selected power level when the ablation element ceases to be in continuous contact with the tissue.
摘要翻译：提供了一种医疗方法，装置和系统，包括使医疗装置的消融元件与待治疗组织接触，选择能量消耗组织的能量水平，将所选功率水平的能量输送到消融元件确定消融元件是否与组织连续接触，以及当消融元件停止与组织连续接触时降低所选择的功率水平。

5. 发明授权

US09387035B2 Bi-modal catheter steering mechanism 有权
标题翻译：双向导管转导机制
公开(公告)号：US09387035B2
公开(公告)日：2016-07-12
申请号：US12546796
申请日：2009-08-25
申请人： Randell Werneth , Ricardo Roman , Timothy J. Corvi , Betty Hu
发明人： Randell Werneth , Ricardo Roman , Timothy J. Corvi , Betty Hu
IPC分类号： A61B18/14 , A61B17/00 , A61B18/00
CPC分类号： A61B18/1492 , A61B5/042 , A61B2017/003 , A61B2017/00323 , A61B2018/00797 , A61B2018/00821 , A61B2018/1407 , A61B2018/1422 , A61B2018/1467 , A61M25/0147 , A61N1/056
摘要： Medical devices, systems, and methods for treating patients with tissue ablation include catheter systems having bi-modal steering mechanisms, which are capable of both linear and loop ablation. In other words, the catheter system may have two different steering modes: two-dimensional and three-dimensional. In the first and second steering modes, the steering actuator may cause one or more portions of the catheter shaft to bend in different planes. A steerable ablation catheter may include treatment elements such as electrodes at its distal end and along the catheter shaft, each of which may map, pace, and ablate.
摘要翻译：用于治疗患有组织消融的患者的医疗装置，系统和方法包括具有双向转向机构的导管系统，其能够进行线性和环路消融。换句话说，导管系统可以具有两种不同的转向模式：二维和三维。在第一和第二转向模式中，转向致动器可导致导管轴的一个或多个部分在不同的平面中弯曲。可引导的消融导管可以包括治疗元件，例如其远端处的电极和沿着导管轴的每个可以映射，步伐和消融的治疗元件。

6. 发明授权

US08571626B2 Mono-phasic action potential electrogram recording catheter, and method 有权
标题翻译：单相动作电位记录导管及方法
公开(公告)号：US08571626B2
公开(公告)日：2013-10-29
申请号：US13604139
申请日：2012-09-05
申请人： Michael Lau , Randell L. Werneth , Timothy J. Corvi , Sumita Bhola , Mark T. Stewart , Michel Haissaguerre , Meleze Hocini
发明人： Michael Lau , Randell L. Werneth , Timothy J. Corvi , Sumita Bhola , Mark T. Stewart , Michel Haissaguerre , Meleze Hocini
IPC分类号： A61B5/042 , A61B18/14 , A61N1/05
CPC分类号： A61B5/042 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00839 , A61B2018/00898 , A61N1/06
摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.
摘要翻译：用于获得单相动作电位（“MAP”）电描记图的导管和方法包括限定纵向轴线的柔性导管主体，以及固定到导管主体远端的远端组件，其限定远端尖端。远端组件具有至少三个MAP记录电极和用于确定参考电位的至少一个参考电极。记录电极各自在至少三个不同的径向方向上与纵向轴线径向距离，限定基本上具有径向对称性的记录几何形状。参考电极是与记录几何形状的纵向距离。可选功能包括可导向的导管轴，一个或多个射频消融电极和专用起搏电极。不同的可能实施例包括具有固定空间布置的记录电极的圆顶壳体和在至少三个柔性环形元件上具有电极阵列的远端环组件。

7. 发明申请

US20120245577A1 COOLING SYSTEMS FOR ELECTRODE ARRAYS 审中-公开
标题翻译：电极阵列冷却系统
公开(公告)号：US20120245577A1
公开(公告)日：2012-09-27
申请号：US13428051
申请日：2012-03-23
申请人： Teresa Ann Mihalik , Alexander J. Asconeguy , Ricardo D. Roman , Timothy J. Corvi
发明人： Teresa Ann Mihalik , Alexander J. Asconeguy , Ricardo D. Roman , Timothy J. Corvi
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00029 , A61B2018/0016 , A61B2018/00214 , A61B2018/00577 , A61B2018/1435 , A61B2018/1467 , A61B2218/002 , F04C2270/0421
摘要： A medical device is disclosed, including a catheter body; an electrode array coupled to the catheter body, the electrode array being transitionable from a substantially linear configuration to a substantially helical configuration; and a fluid conduit coupled to the catheter body spaced apart from the electrode array, wherein the fluid conduit is transitionable from a substantially linear configuration to a substantially helical configuration. The device may include a fluid source in communication with the fluid conduit and a radiofrequency signal generator coupled to the electrode array.
摘要翻译：公开了一种医疗装置，包括导管体; 电极阵列，其耦合到所述导管主体，所述电极阵列可从基本上线性的构型转变为基本上螺旋的构造; 以及耦合到与电极阵列间隔开的导管主体的流体导管，其中流体导管可从基本上线性的构型转变为基本上螺旋的构型。该装置可以包括与流体导管连通的流体源和耦合到该电极阵列的射频信号发生器。

8. 发明授权

US10064678B2 Semi-circular pulmonary vein ablation catheter 有权
公开(公告)号：US10064678B2
公开(公告)日：2018-09-04
申请号：US13281761
申请日：2011-10-26
申请人： Timothy J. Corvi , Ricardo D. Roman
发明人： Timothy J. Corvi , Ricardo D. Roman
IPC分类号： A61B18/14 , A61B17/00 , A61B18/00 , A61B18/18
摘要： A medical device is disclosed, including a handle assembly; an elongate body coupled to the handle assembly, the elongate body defining a guide wire lumen therethrough; and a substantially semi-circular electrode array coupled to the elongate body. The device may include a substantially rigid shaft extending distally from the elongate body and defining a lumen therethrough, the shaft including a substantially rigid segment, and a flexible coil coaxial with and extending distally from the shaft.

9. 发明申请

US20110028966A1 MONO-PHASIC ACTION POTENTIAL ELECTROGRAM RECORDING CATHETER, AND METHOD 有权
公开(公告)号：US20110028966A1
公开(公告)日：2011-02-03
申请号：US12533903
申请日：2009-07-31
申请人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART
发明人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART
IPC分类号： A61B18/14 , A61N1/05
CPC分类号： A61B5/042 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00839 , A61B2018/00898 , A61N1/06
摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.

10. 发明申请

US20110028820A1 MONO-PHASIC ACTION POTENTIAL ELECTROGRAM RECORDING CATHETER, AND METHOD 有权
标题翻译：单相电动势电位记录导管及方法
公开(公告)号：US20110028820A1
公开(公告)日：2011-02-03
申请号：US12511707
申请日：2009-07-29
申请人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART
发明人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART
IPC分类号： A61B5/04 , A61N1/05 , A61B18/14
CPC分类号： A61B5/042 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00839 , A61B2018/00898 , A61N1/06
摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.
摘要翻译：用于获得单相动作电位（“MAP”）电描记图的导管和方法包括限定纵向轴线的柔性导管主体，以及固定到导管主体远端的远端组件，其限定远端尖端。远端组件具有至少三个MAP记录电极和用于确定参考电位的至少一个参考电极。记录电极各自在至少三个不同的径向方向上与纵向轴线径向距离，限定基本上具有径向对称性的记录几何形状。参考电极是与记录几何形状的纵向距离。可选功能包括可导向的导管轴，一个或多个射频消融电极和专用起搏电极。不同的可能实施例包括具有固定空间布置的记录电极的圆顶壳体和在至少三个柔性环形元件上具有电极阵列的远端环组件。

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