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1. 发明授权

US08542962B2 Preconditioned illuminator system and method 有权
标题翻译：预处理照明系统及方法
公开(公告)号：US08542962B2
公开(公告)日：2013-09-24
申请号：US12540755
申请日：2009-08-13
申请人： Ronald T. Smith , Dean Y. Lin , Jack R. Auld , Timothy C. Ryan
发明人： Ronald T. Smith , Dean Y. Lin , Jack R. Auld , Timothy C. Ryan
IPC分类号： G02B6/32 , A61B1/07
CPC分类号： B23P11/025 , A61B90/30 , A61B2090/306 , A61F9/007 , Y10T29/49865
摘要： Embodiments of endo-illuminators and related methods are disclosed. One embodiment of an illuminator can comprise a cannula defining a passage, an optical element disposed at an end of the cannula, and an optical fiber running through the passage with the distal end of the optical fiber in contact with the optical element. The optical fiber includes at least a heat preconditioned distal portion that terminates in the distal end that is in contact with the optical element. One embodiment of a method can comprise inserting an optical fiber through a proximal portion of a cannula and optical element assembly until the distal end of the optical fiber contacts the optical element, heating a distal portion of the optical fiber to between a softening temperature and a melting temperature for a period of time to cause the distal portion to axially shrink and moving the optical element so that the optical element is in contact with the distal end of the optical fiber when the distal portion of the optical fiber has axially shrunk. Moving the optical element so that the optical element is in contact with the distal end of the optical fiber when the distal portion of the optical fiber has axially shrunk can comprise applying a force to the cannula and optical element assembly to maintain the optical element in continuous contact with the distal end of the optical fiber while the optical fiber axially shrinks.
摘要翻译：公开了内照射器和相关方法的实施例。照明器的一个实施例可以包括限定通道的插管，设置在插管端部的光学元件以及穿过通道的光纤，其中光纤的远端与光学元件接触。光纤至少包括热预处理的远端部分，其终止于与光学元件接触的远端。方法的一个实施例可以包括通过套管和光学元件组件的近端部分插入光纤，直到光纤的远端接触光学元件，将光纤的远端部分加热到软化温度和熔化温度一段时间，使得远端部分轴向收缩并移动光学元件，使得当光纤的远端部分轴向收缩时，光学元件与光纤的远端接触。当光纤的远端轴向收缩时，移动光学元件使得光学元件与光纤的远端接触可包括向套管和光学元件组件施加力以将光学元件保持连续当光纤轴向收缩时，与光纤的远端接触。

2. 发明授权

US08498506B2 Preconditioned illuminator system and method 有权
标题翻译：预处理照明系统及方法
公开(公告)号：US08498506B2
公开(公告)日：2013-07-30
申请号：US13430235
申请日：2012-03-26
申请人： Ronald T. Smith , Dean Y. Lin , Jack R. Auld , Timothy C. Ryan
发明人： Ronald T. Smith , Dean Y. Lin , Jack R. Auld , Timothy C. Ryan
IPC分类号： G02B6/32 , A61B1/07
CPC分类号： B23P11/025 , A61B90/30 , A61B2090/306 , A61F9/007 , Y10T29/49865
摘要： Embodiments of endo-illuminators and related methods are disclosed. One embodiment of an illuminator can comprise a cannula defining a passage, an optical element disposed at an end of the cannula, and an optical fiber running through the passage with the distal end of the optical fiber in contact with the optical element. The optical fiber includes at least a heat preconditioned distal portion that terminates in the distal end that is in contact with the optical element.
摘要翻译：公开了内照射器和相关方法的实施例。照明器的一个实施例可以包括限定通道的插管，设置在插管端部的光学元件以及穿过通道的光纤，其中光纤的远端与光学元件接触。光纤至少包括热预处理的远端部分，其终止于与光学元件接触的远端。

3. 发明授权

US5358689A Hollow fiber blood oxygenator 失效
标题翻译：中空纤维血液充氧器
公开(公告)号：US5358689A
公开(公告)日：1994-10-25
申请号：US31172
申请日：1993-04-15
申请人： Kenneth A. Jones , Francis M. Servas , Timothy C. Ryan , Gregory G. Ulrich
发明人： Kenneth A. Jones , Francis M. Servas , Timothy C. Ryan , Gregory G. Ulrich
IPC分类号： A61M1/14 , A61M1/16 , A61M1/36 , B01D63/02 , F28D7/02 , F28F13/00 , F28F21/06
CPC分类号： A61M1/1698 , A61M1/1625 , A61M1/1629 , B01D63/02 , F28D7/024 , F28F13/003 , F28F21/062 , A61M1/3627 , B01D2313/146 , B01D2313/38 , F28F2265/16 , Y10S128/03 , Y10S261/28
摘要： A hollow fiber blood oxygenator is provided having an plurality of enclosed, coaxial heat exchanger coils, having a common header to insure uniform temperature in the coils. An enclosed fiber bundle is concentrically positioned inside the heat exchanger coils to define a flow path around the coils and through the fiber bundle. The heat exchanger coils and the outside of the fiber bundle are tapered to provide a close fit. Gas manifolds direct gas flow to and from the hollow fibers.
摘要翻译：提供一种中空纤维血液充氧器，其具有多个封闭的同轴热交换器线圈，其具有共同的头部以确保线圈中的均匀温度。封闭的纤维束同心地位于热交换器盘管的内部，以限定围绕线圈和通过纤维束的流动路径。热交换器线圈和纤维束的外侧是锥形的以提供紧密配合。气体歧管直接将气体流入和流出中空纤维。

4. 发明申请

US20100042080A1 Preconditioned Illuminator System and Method 有权
标题翻译：预处理照明系统和方法
公开(公告)号：US20100042080A1
公开(公告)日：2010-02-18
申请号：US12540755
申请日：2009-08-13
申请人： Ronald T. Smith , Dean Y. Lin , Jack R. Auld , Timothy C. Ryan
发明人： Ronald T. Smith , Dean Y. Lin , Jack R. Auld , Timothy C. Ryan
IPC分类号： A61B18/00
CPC分类号： B23P11/025 , A61B90/30 , A61B2090/306 , A61F9/007 , Y10T29/49865
摘要： Embodiments of endo-illuminators and related methods are disclosed. One embodiment of an illuminator can comprise a cannula defining a passage, an optical element disposed at an end of the cannula, and an optical fiber running through the passage with the distal end of the optical fiber in contact with the optical element. The optical fiber includes at least a heat preconditioned distal portion that terminates in the distal end that is in contact with the optical element. One embodiment of a method can comprise inserting an optical fiber through a proximal portion of a cannula and optical element assembly until the distal end of the optical fiber contacts the optical element, heating a distal portion of the optical fiber to between a softening temperature and a melting temperature for a period of time to cause the distal portion to axially shrink and moving the optical element so that the optical element is in contact with the distal end of the optical fiber when the distal portion of the optical fiber has axially shrunk. Moving the optical element so that the optical element is in contact with the distal end of the optical fiber when the distal portion of the optical fiber has axially shrunk can comprise applying a force to the cannula and optical element assembly to maintain the optical element in continuous contact with the distal end of the optical fiber while the optical fiber axially shrinks.
摘要翻译：公开了内照射器和相关方法的实施例。照明器的一个实施例可以包括限定通道的插管，设置在插管端部的光学元件以及穿过通道的光纤，其中光纤的远端与光学元件接触。光纤至少包括热预处理的远端部分，其终止于与光学元件接触的远端。方法的一个实施例可以包括通过套管和光学元件组件的近端部分插入光纤，直到光纤的远端接触光学元件，将光纤的远端部分加热到软化温度和熔化温度一段时间，使得远端部分轴向收缩并移动光学元件，使得当光纤的远端部分轴向收缩时，光学元件与光纤的远端接触。当光纤的远端轴向收缩时，移动光学元件使得光学元件与光纤的远端接触可包括向套管和光学元件组件施加力以将光学元件保持连续当光纤轴向收缩时，与光纤的远端接触。

5. 发明授权

US5954696A Pressure infusion pump 失效
标题翻译：压力输液泵
公开(公告)号：US5954696A
公开(公告)日：1999-09-21
申请号：US990362
申请日：1997-12-15
申请人： Timothy C. Ryan
发明人： Timothy C. Ryan
IPC分类号： A61M5/148 , A61M5/168 , A61M5/142
CPC分类号： A61M5/16831 , A61M5/1483 , A61M2205/8225 , Y10S128/12
摘要： A portable, ambulatory infusion pump for use with standard pre-filled infusion medicament containers is powered by a miniature compressed gas cylinder coupled to a mechanical pressure regulator which supplies regulated gas at a substantially constant pressure to an inflatable bladder. The bladder is positioned between a substantially rigid pressure surface and a moveable pressure transfer plate and pushes against the transfer plate when inflated. A pre-filled medicament container is positioned over the pressure transfer plate and is squeezed between the transfer plate and the pump housing cover as the plate is displaced in response to inflation of the flexible bladder. A safety interlock assembly is connected between the pressure regulator and the inflatable bladder and prevents inflation of the bladder unless the housing cover is completely closed. Upon inadvertent opening of the pump, the internal pressurization system is vented to atmosphere.
摘要翻译：用于与标准预灌注输液药物容器一起使用的便携式移动式输液泵由联接到机械压力调节器的微型压缩气瓶提供动力，所述机械压力调节器以基本上恒定的压力向被充气的气囊提供调节气体。气囊位于基本上刚性的压力表面和可移动的压力传递板之间，并且在充气时推动传递板。预填充的药物容器位于压力传递板上方，并随着弹性囊的膨胀而使板移动而在传递板和泵壳体盖之间被挤压。安全联锁组件连接在压力调节器和可膨胀气囊之间，并防止气囊膨胀，除非外壳盖完全关闭。在无意中打开泵时，内部加压系统排放到大气中。

6. 发明授权

US5234663A Hollow fiber blood oxygenator 失效
标题翻译：中空纤维血液充氧器
公开(公告)号：US5234663A
公开(公告)日：1993-08-10
申请号：US853501
申请日：1992-03-18
申请人： Kenneth A. Jones , Francis M. Servas , Timothy C. Ryan , Gregory G. Ulrich
发明人： Kenneth A. Jones , Francis M. Servas , Timothy C. Ryan , Gregory G. Ulrich
IPC分类号： A61M1/16 , A61M1/36 , B01D63/02 , F28F21/06
CPC分类号： A61M1/1698 , A61M1/1625 , A61M1/1629 , B01D63/02 , B01D63/021 , B01D63/025 , F28F21/062 , A61M1/3627 , B01D2313/38 , Y10S128/03 , Y10S261/28
摘要： A hollow fiber blood oxygenator is provided having a plurality of enclosed, coaxial heat exchanger coils, having a common header to insure uniform temperature in the coils. An enclosed fiber bundle is concentrically positioned inside the heat exchanger coils to define a flow path around the coils and through the fiber bundle. The heat exchanger coils and the outside of the fiber bundle are tapered to provide a close fit. Gas manifolds direct gas flow to and from the hollow fibers.
摘要翻译：提供了一种中空纤维血液充氧器，其具有多个封闭的同轴热交换器线圈，其具有共同的头部以确保线圈中的均匀温度。封闭的纤维束同心地位于热交换器盘管的内部，以限定围绕线圈和通过纤维束的流动路径。热交换器线圈和纤维束的外侧是锥形的以提供紧密配合。气体歧管直接将气体流入和流出中空纤维。

7. 发明授权

US5456284A Elastomeric valve assembly 失效
标题翻译：弹性阀组件
公开(公告)号：US5456284A
公开(公告)日：1995-10-10
申请号：US59804
申请日：1993-05-10
申请人： Timothy C. Ryan , Charles C. Hart , Mark A. Ritchart , Donald L. Gadberry
发明人： Timothy C. Ryan , Charles C. Hart , Mark A. Ritchart , Donald L. Gadberry
IPC分类号： A61M39/06 , F16K15/14 , A61B1/01
CPC分类号： A61B1/018 , A61B1/00137 , A61M39/0606 , F16K15/147 , A61M2039/0633 , A61M2039/0646 , Y10T137/7876
摘要： A medical access device is adapted to receive an instrument and comprises a housing defining an inner channel and a valve disposed in the channel to form a seal with the housing. The valve includes an outer wall and a pair of inner walls extending in distally converging relationship to define a slot. At least one compression member extends between the outer wall and an associated one of the inner walls. The compression member is compressed in response to insertion of the instrument and exerts a force on the associated inner wall when compressed to reduce leakage of the valve when the instrument is inserted. A funnel is provided at the distal end of the valve to facilitate backloading of the instrument.
摘要翻译：医疗接入装置适于接收仪器并且包括限定内部通道的壳体和设置在通道中的阀，以与壳体形成密封。该阀包括一个外壁和一对内壁，该内壁以远端会聚的关系延伸以限定槽。至少一个压缩构件在外壁和相关联的一个内壁之间延伸。压缩构件被响应于仪器的插入而被压缩，并在压缩时对相关联的内壁施加力，以减少当仪器被插入时阀的泄漏。在阀的远端处提供漏斗以便于仪器的背负。

8. 发明授权

US5124127A Hollow fiber blood oxygenator 失效
标题翻译：中空纤维血液氧化剂
公开(公告)号：US5124127A
公开(公告)日：1992-06-23
申请号：US302422
申请日：1989-01-26
申请人： Kenneth A. Jones , Francis M. Servas , Timothy C. Ryan , Gregory G. Ulrich
发明人： Kenneth A. Jones , Francis M. Servas , Timothy C. Ryan , Gregory G. Ulrich
IPC分类号： A61M1/14 , A61M1/16 , A61M1/36 , B01D63/02 , F28D7/02 , F28F13/00 , F28F21/06
CPC分类号： A61M1/1698 , A61M1/1625 , A61M1/1629 , B01D63/02 , F28D7/024 , F28F13/003 , F28F21/062 , A61M1/3627 , B01D2313/146 , B01D2313/38 , F28F2265/16 , Y10S128/03 , Y10S261/28
摘要： A hollow fiber blood oxygenator is provided having a plurality of enclosed, coaxial heat exchanger coils, having a common header to insure uniform temperature in the coils. An enclosed fiber bundle is concentrically positioned inside the heat exchanger coils to define a flow path around the coils and through the fiber bundle. The heat exchanger coils and the outside of the fiber bundle are tapered to provide a close fit. Gas manifolds direct gas flow to and from the hollow fibers.
摘要翻译：中空纤维血液充氧器（12）设置有多个封闭的同轴热交换器线圈（16），其具有共同的头部（46），以确保线圈中的均匀温度。封闭的纤维束（22）同心地位于热交换器盘管的内部，以限定围绕线圈和通过纤维束的流动路径。热交换器线圈和纤维束的外侧是锥形的以提供紧密配合。气体歧管（32,40）直接将气体流入和流出中空纤维。

9. 发明申请

US20190175406A1 MULTI-CORE FIBER FOR A MULTI-SPOT LASER PROBE 审中-公开
公开(公告)号：US20190175406A1
公开(公告)日：2019-06-13
申请号：US16218365
申请日：2018-12-12
申请人： Christopher Cook , Chenguang Diao , Mark Harrison Farley , Alireza Mirsepassi , Timothy C. Ryan
发明人： Christopher Cook , Chenguang Diao , Mark Harrison Farley , Alireza Mirsepassi , Timothy C. Ryan
IPC分类号： A61F9/008 , A61B18/22 , G02B6/38
摘要： The present disclosure relates to a multi-core optical fiber cable (MCF). In some embodiments, an MCF comprises a plurality of cores, a cladding surrounding the plurality of cores, wherein a refractive index of one or more of the plurality of cores is greater than a refractive index of the cladding, and a coating surrounding the cladding, a distal end free of the coating and having a reduced diameter. The MCF also comprise an annular gap formed between the distal end of the MCF and the inner surface of the cannula, wherein the concentricity of the distal end of the MCF with the inner passage of the cannula is maintained.

10. 发明申请

US20130081253A1 PRECONDITIONED ILLUMINATOR SYSTEM AND METHOD 有权
标题翻译：预先确定的照明系统和方法
公开(公告)号：US20130081253A1
公开(公告)日：2013-04-04
申请号：US13430235
申请日：2012-03-26
申请人： Ronald T. Smith , Dean Y. Lin , Jack R. Auld , Timothy C. Ryan
发明人： Ronald T. Smith , Dean Y. Lin , Jack R. Auld , Timothy C. Ryan
IPC分类号： B23P11/02
CPC分类号： B23P11/025 , A61B90/30 , A61B2090/306 , A61F9/007 , Y10T29/49865
摘要： Embodiments of endo-illuminators and related methods are disclosed. One embodiment of an illuminator can comprise a cannula defining a passage, an optical element disposed at an end of the cannula, and an optical fiber running through the passage with the distal end of the optical fiber in contact with the optical element. The optical fiber includes at least a heat preconditioned distal portion that terminates in the distal end that is in contact with the optical element.
摘要翻译：公开了内照射器和相关方法的实施例。照明器的一个实施例可以包括限定通道的插管，设置在插管端部的光学元件以及穿过通道的光纤，其中光纤的远端与光学元件接触。光纤至少包括热预处理的远端部分，其终止于与光学元件接触的远端。

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