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1. 发明授权

US09446192B2 Implantable pump with reservoir level detector 有权
标题翻译：带液位检测器的可植入泵
公开(公告)号：US09446192B2
公开(公告)日：2016-09-20
申请号：US12943093
申请日：2010-11-10
申请人： Thierry Utard , Jean-Sebastien Petithory , Philippe Margairaz , Rocco Crivelli , Alec Ginggen
发明人： Thierry Utard , Jean-Sebastien Petithory , Philippe Margairaz , Rocco Crivelli , Alec Ginggen
IPC分类号： A61K9/22 , A61M5/168 , A61M5/142
CPC分类号： A61M5/1684 , A61M5/14276 , A61M2205/3317 , A61M2205/3389
摘要： An implantable pump includes a base plate and a can that are parts of the pump housing. The base plate bottom divides the housing into a first electronics chamber and a second chamber. A bellows mechanism is connected to the base plate and is disposed within the second chamber. The bellow mechanism has an expandable sidewall and a bottom plate. The bellow mechanism divides the second chamber into a medicament receiving portion and a non-medicament-receiving portion. The bellow mechanism has an intermediate plate disposed within the medicament-receiving portion. A coil is disposed in a recess on the lower surface of the base plate, and the coil is spaced from an internal wall of the recess. The amount of fluid remaining in the implantable pump can be monitored by energizing the coil. A primary magnetic field is generated by the energized coil. A secondary magnetic field, which is dependant on the position of the bottom and intermediate plate of the bellow mechanism, couples back to the primary field affecting the electrical characteristics of the coil. The amount of fluid remaining in the reservoir is determined based on the resulting changes in the electrical characteristics of the coil.
摘要翻译：可植入泵包括作为泵壳体的部件的基板和罐。基板底部将壳体分成第一电子室和第二室。波纹管机构连接到基板并且设置在第二室内。波纹管机构具有可膨胀的侧壁和底板。波纹管机构将第二腔室分成药物接收部分和非药物接收部分。波纹管机构具有设置在药物接收部分内的中间板。线圈设置在基板的下表面上的凹部中，线圈与凹部的内壁间隔开。可以通过对线圈通电来监测可植入泵中剩余的流体量。由励磁线圈产生初级磁场。取决于波纹管机构的底板和中间板的位置的次级磁场耦合回到影响线圈的电特性的初级场。基于所得到的线圈的电特性的变化来确定储存器中剩余的流体的量。

2. 发明授权

US08518023B2 Tools and methods for programming an implantable valve 有权
公开(公告)号：US08518023B2
公开(公告)日：2013-08-27
申请号：US12609641
申请日：2009-10-30
申请人： Danillo Roth , Stefano Azzalin , Thierry Utard , Martin Pfleiderer
发明人： Danillo Roth , Stefano Azzalin , Thierry Utard , Martin Pfleiderer
IPC分类号： A61M5/00 , A61K9/22
CPC分类号： A61M27/006 , A61M2202/0464 , A61M2205/3515 , F16K31/08 , F16K37/0041 , Y10T137/7878 , Y10T137/8242
摘要： Integrated tools for noninvasively reading and adjusting an implantable, magnetically adjustable valve, and methods of use are disclosed. The tools include magnetic or electronic reading of the valve, and magnetic or electromagnetic adjustment of the valve. In use, the tools are positioned above or in contact with the patient's skin, in proximity to the valve.

3. 发明申请

US20110105991A1 Tools and methods for programming an implantable valve 有权
标题翻译：用于编程可植入阀的工具和方法
公开(公告)号：US20110105991A1
公开(公告)日：2011-05-05
申请号：US12609641
申请日：2009-10-30
申请人： Danillo Roth , Stefano Azzalin , Thierry Utard , Martin Pfleiderer
发明人： Danillo Roth , Stefano Azzalin , Thierry Utard , Martin Pfleiderer
IPC分类号： F16K31/06 , A61M1/00
CPC分类号： A61M27/006 , A61M2202/0464 , A61M2205/3515 , F16K31/08 , F16K37/0041 , Y10T137/7878 , Y10T137/8242
摘要： Integrated tools for noninvasively reading and adjusting an implantable, magnetically adjustable valve, and methods of use are disclosed. The tools include magnetic or electronic reading of the valve, and magnetic or electromagnetic adjustment of the valve. In use, the tools are positioned above or in contact with the patient's skin, in proximity to the valve.
摘要翻译：公开了用于非侵入性读取和调节可植入的磁力可调节阀的集成工具和使用方法。这些工具包括阀门的磁性或电子读数，以及阀门的磁性或电磁调节。在使用中，工具位于患者皮肤的上方或与其接触的位置。

4. 发明申请

US20070106280A1 IMPLANTABLE PUMP WITH RESERVOIR LEVEL DETECTOR 有权
标题翻译：具有储存水平检测器的可注入泵
公开(公告)号：US20070106280A1
公开(公告)日：2007-05-10
申请号：US11552343
申请日：2006-10-24
申请人： Thierry Utard , Jean-Sebastien Petithory , Philippe Margairaz , Rocco Crivelli , Alec Ginggen
发明人： Thierry Utard , Jean-Sebastien Petithory , Philippe Margairaz , Rocco Crivelli , Alec Ginggen
IPC分类号： A61K9/22
CPC分类号： A61M5/1684 , A61M5/14276 , A61M2205/3317 , A61M2205/3389
摘要： An implantable pump includes a base plate and a can that are parts of the pump housing. The base plate bottom divides the housing into a first electronics chamber and a second chamber. A bellows mechanism is connected to the base plate and is disposed within the second chamber. The bellow mechanism has an expandable sidewall and a bottom plate. The bellow mechanism divides the second chamber into a medicament receiving portion and a non-medicament-receiving portion. The bellow mechanism has an intermediate plate disposed within the medicament-receiving portion. A coil is disposed in a recess on the lower surface of the base plate, and the coil is spaced from an internal wall of the recess. The amount of fluid remaining in the implantable pump can be monitored by energizing the coil. A primary magnetic field is generated by the energized coil. A secondary magnetic field, which is dependant on the position of the bottom and intermediate plate of the bellow mechanism, couples back to the primary field affecting the electrical characteristics of the coil. The amount of fluid remaining in the reservoir is determined based on the resulting changes in the electrical characteristics of the coil.
摘要翻译：可植入泵包括作为泵壳体的部件的基板和罐。基板底部将壳体分成第一电子室和第二室。波纹管机构连接到基板并且设置在第二室内。波纹管机构具有可膨胀的侧壁和底板。波纹管机构将第二腔室分成药物接收部分和非药物接收部分。波纹管机构具有设置在药物接收部分内的中间板。线圈设置在基板的下表面上的凹部中，线圈与凹部的内壁间隔开。可以通过对线圈通电来监测可植入泵中剩余的流体量。由励磁线圈产生初级磁场。取决于波纹管机构的底板和中间板的位置的次级磁场耦合回到影响线圈的电特性的初级场。基于所得到的线圈的电特性的变化来确定储存器中剩余的流体的量。

5. 发明申请

US20070245258A1 Graphical user interface of an external control device for controlling an implantable medical device while minimizing human error 审中-公开
标题翻译：用于控制可植入医疗装置的外部控制装置的图形用户界面，同时最小化人为错误
公开(公告)号：US20070245258A1
公开(公告)日：2007-10-18
申请号：US11403987
申请日：2006-04-13
申请人： Alec Ginggen , Thierry Utard , Yanik Tardy , Thierry Pipoz , Olivier Chossat
发明人： Alec Ginggen , Thierry Utard , Yanik Tardy , Thierry Pipoz , Olivier Chossat
IPC分类号： G06F17/00
CPC分类号： A61N1/37247 , A61M5/14276 , A61M2205/3523 , A61M2205/502 , G16H40/63
摘要： A graphical user interface of an external control device for controlling operation of an implantable medical device while minimizing the occurrence of human error. The graphical user interface displays the operating parameter of the implantable medical device simultaneously as an Arabic numeral and a graphical representation. When a parameter value is adjusted, the current and adjusted values are simultaneously displayed as both an Arabic numeral and graphical representation. Other means are described for increasing the probability of detection of an error during entry of an operating parameter value prior to implementation. Execution of the graphical user interface is subject to interruption. When function of the graphical user interface programming is restored operation resumes from that which it left off prior to interruption.
摘要翻译：用于控制可植入医疗装置的操作的外部控制装置的图形用户界面，同时最小化人为错误的发生。图形用户界面同时显示可植入医疗设备的操作参数，如阿拉伯数字和图形表示。当调整参数值时，当前和调整的值同时显示为阿拉伯数字和图形表示。描述了用于在实施之前增加在操作参数值的输入期间检测到错误的可能性的其它手段。图形用户界面的执行会中断。当图形用户界面编程的功能恢复时，中断之前从停止运行的程序恢复运行。

6. 发明申请

US20120165794A1 Pill Catchers 审中-公开
公开(公告)号：US20120165794A1
公开(公告)日：2012-06-28
申请号：US12976761
申请日：2010-12-22
申请人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , Mark S. Zeiner , Mark D. Overmyer , Joseph B. Kraimer , Jeff Shimizu , Rocco Crivelli , Yanik Tardy , Thierry Utard , Juergen Burger , Toralf Bork , Martin Pfleiderer , Olivier Chossat
发明人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , Mark S. Zeiner , Mark D. Overmyer , Joseph B. Kraimer , Jeff Shimizu , Rocco Crivelli , Yanik Tardy , Thierry Utard , Juergen Burger , Toralf Bork , Martin Pfleiderer , Olivier Chossat
IPC分类号： A61M31/00
CPC分类号： A61B1/041 , A61B1/00147 , A61F5/0013 , A61M31/002
摘要： Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.

7. 发明授权

US07905878B2 Implantable pump with reservoir level detector 有权
标题翻译：带液位检测器的可植入泵
公开(公告)号：US07905878B2
公开(公告)日：2011-03-15
申请号：US11552343
申请日：2006-10-24
申请人： Thierry Utard , Jean-Sebastien Petithory , Philippe Margairaz , Rocco Crivelli , Alec Ginggen
发明人： Thierry Utard , Jean-Sebastien Petithory , Philippe Margairaz , Rocco Crivelli , Alec Ginggen
IPC分类号： A61M37/00 , A61K9/22
CPC分类号： A61M5/1684 , A61M5/14276 , A61M2205/3317 , A61M2205/3389
摘要： An implantable pump includes a base plate and a can that are parts of the pump housing. The base plate bottom divides the housing into a first electronics chamber and a second chamber. A bellows mechanism is connected to the base plate and is disposed within the second chamber. The bellow mechanism has an expandable sidewall and a bottom plate. The bellow mechanism divides the second chamber into a medicament receiving portion and a non-medicament-receiving portion. The bellow mechanism has an intermediate plate disposed within the medicament-receiving portion. A coil is disposed in a recess on the lower surface of the base plate, and the coil is spaced from an internal wall of the recess. The amount of fluid remaining in the implantable pump can be monitored by energizing the coil. A primary magnetic field is generated by the energized coil. A secondary magnetic field, which is dependant on the position of the bottom and intermediate plate of the bellow mechanism, couples back to the primary field affecting the electrical characteristics of the coil. The amount of fluid remaining in the reservoir is determined based on the resulting changes in the electrical characteristics of the coil.
摘要翻译：可植入泵包括作为泵壳体的部件的基板和罐。基板底部将壳体分成第一电子室和第二室。波纹管机构连接到基板并且设置在第二室内。波纹管机构具有可膨胀的侧壁和底板。波纹管机构将第二腔室分成药物接收部分和非药物接收部分。波纹管机构具有设置在药物接收部分内的中间板。线圈设置在基板的下表面上的凹部中，线圈与凹部的内壁间隔开。可以通过对线圈通电来监测可植入泵中剩余的流体量。由励磁线圈产生初级磁场。取决于波纹管机构的底板和中间板的位置的次级磁场耦合回到影响线圈的电特性的初级场。基于所得到的线圈的电特性的变化来确定储存器中剩余的流体的量。

8. 发明申请

US20110060283A1 IMPLANTABLE PUMP WITH RESERVOIR LEVEL DETECTOR 审中-公开
标题翻译：具有储存水平检测器的可注入泵
公开(公告)号：US20110060283A1
公开(公告)日：2011-03-10
申请号：US12943093
申请日：2010-11-10
申请人： THIERRY UTARD , Jean-Sebastien Petithory , Philippe Margairaz , Rocco Crivelli , Alec Ginggen
发明人： THIERRY UTARD , Jean-Sebastien Petithory , Philippe Margairaz , Rocco Crivelli , Alec Ginggen
IPC分类号： A61M5/142
CPC分类号： A61M5/1684 , A61M5/14276 , A61M2205/3317 , A61M2205/3389
摘要： An implantable pump includes a base plate and a can that are parts of the pump housing. The base plate bottom divides the housing into a first electronics chamber and a second chamber. A bellows mechanism is connected to the base plate and is disposed within the second chamber. The bellow mechanism has an expandable sidewall and a bottom plate. The bellow mechanism divides the second chamber into a medicament receiving portion and a non-medicament-receiving portion. The bellow mechanism has an intermediate plate disposed within the medicament-receiving portion. A coil is disposed in a recess on the lower surface of the base plate, and the coil is spaced from an internal wall of the recess. The amount of fluid remaining in the implantable pump can be monitored by energizing the coil. A primary magnetic field is generated by the energized coil. A secondary magnetic field, which is dependant on the position of the bottom and intermediate plate of the bellow mechanism, couples back to the primary field affecting the electrical characteristics of the coil. The amount of fluid remaining in the reservoir is determined based on the resulting changes in the electrical characteristics of the coil.
摘要翻译：可植入泵包括作为泵壳体的部件的基板和罐。基板底部将壳体分成第一电子室和第二室。波纹管机构连接到基板并且设置在第二室内。波纹管机构具有可膨胀的侧壁和底板。波纹管机构将第二腔室分成药物接收部分和非药物接收部分。波纹管机构具有设置在药物接收部分内的中间板。线圈设置在基板的下表面上的凹部中，线圈与凹部的内壁间隔开。可以通过对线圈通电来监测可植入泵中剩余的流体量。由励磁线圈产生初级磁场。取决于波纹管机构的底板和中间板的位置的次级磁场耦合回到影响线圈的电特性的初级场。基于所得到的线圈的电特性的变化来确定储存器中剩余的流体的量。

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