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    • 7. 发明授权
    • Solid-state laser apparatus
    • 固态激光装置
    • US5740194A
    • 1998-04-14
    • US616324
    • 1996-03-15
    • Takahiro UchidaShinichi Nakayama
    • Takahiro UchidaShinichi Nakayama
    • H01S3/094H01S3/0941H01S3/091
    • H01S3/0941H01S3/094076H01S3/09408H01S3/1022
    • A laser system is provided with a plurality of light emitting diodes arranged to energize the laser source. The individual diodes have separate controls so that they may be turned on separately from one another for different periods of time and to produce different amounts of illumination. A controller such as a CPU may be programmed to actuate the controllers in a desired manner to achieve to a controlled light profile upgrading versatility and accuracy of laser systems. In addition to sequencing individual light emitting diodes in various combinations, the diodes may be energized simultaneously in various combinations. A first combination may be illuminated for a relatively long time and a second combination energized to overlap part or all of the period of that first combination, or even to extend beyond the period of the first. Thus, in addition to adjusting pulse width time, time spacing between pulses and overlap of pulses may be adjusted as well as light amplitude of individual diode light sources.
    • 激光系统设置有多个被布置成激励激光源的发光二极管。 各个二极管具有单独的控制,使得它们可以在不同的时间段内彼此分开接通并产生不同量的照明。 诸如CPU的控制器可以被编程为以期望的方式致动控制器,以实现激光系统的可控光分布,从而提高激光系统的多功能性和精度。 除了以各种组合对各个发光二极管进行排序之外,二极管可以以各种组合同时通电。 第一组合可以被照亮相对长的时间,并且第二组合被激励以与第一组合的周期的部分或全部重叠,或者甚至延伸超过第一组合的周期。 因此,除了调整脉冲宽度时间之外,可以调节脉冲之间的时间间隔和脉冲的重叠以及各个二极管光源的光振幅。
    • 8. 发明授权
    • Laser apparatus and accessible, compact cooling system thereof having
interchangeable flow restricting members
    • 具有可互换流量限制构件的激光装置和可及的,紧凑的冷却系统
    • US5572538A
    • 1996-11-05
    • US4581
    • 1993-01-14
    • Minoru SaitohAkira UesugiTakahiro Uchida
    • Minoru SaitohAkira UesugiTakahiro Uchida
    • H01S3/04H01S3/042
    • H01S3/042H01S3/0407
    • A laser apparatus includes an electric power supply system and a cooling water supply system. Both the electric terminals of the electric power supply system for connection with an external power cable and ports of the cooling water supply system for communicating with external pipes are placed in the forward part of the laser apparatus for facilitating its maintenance. A storage tank stores cooling water to be supplied to a laser oscillator. Both an ion exchanger and a filter are commonly housed in the tank to downsize the apparatus, to minimize the water leakage and to effectively purify the cooling water. Interchangeable flow control valves are provided for different electric power frequencies. According to the available power frequency an appropriate one of the valves is chosen and connected to internal piping to achieve the desired flow rate of the cooling water supplied to the laser oscillator.
    • 激光装置包括电力供应系统和冷却水供应系统。 用于与外部电力电缆连接的电力供应系统的电气端子和用于与外部管道连通的冷却水供应系统的端口都放置在激光设备的前部,以便于维护。 储罐储存供应给激光振荡器的冷却水。 离子交换器和过滤器都通常容纳在罐中以减小设备的尺寸,以最小化漏水并且有效地净化冷却水。 为不同的电力频率提供可互换的流量控制阀。 根据可用的功率频率,选择适当的一个阀并将其连接到内部管道,以实现供应给激光振荡器的冷却水的期望流量。
    • 9. 发明授权
    • Sustained release preparation for tissue regeneration therapy
    • 组织再生治疗的缓释制剂
    • US08617614B2
    • 2013-12-31
    • US12446157
    • 2007-10-18
    • Yoshiki SakaiTakahiro Uchida
    • Yoshiki SakaiTakahiro Uchida
    • A61K9/50A61K31/44A01N43/40
    • A61K31/4406A61K9/1647
    • The present invention provides a microsphere with a slow-release period from about two weeks to about four weeks following administration, to enable a higher content of a drug to be included, to suppress an initial burst of the drug, and to maintain an optimal, effective blood concentration during the slow-release period. In a microsphere containing a drug and polylactic acid/glycolic acid (PLGA) copolymer, the amount of PLGA copolymer per part by weight of the drug is from about 3 to about 10 parts by weight; the average particle size of the microsphere is from about 20 to about 50 μm; and (3) the PLGA copolymer has a weight-average molecular weight from about 10,000 to about 50,000 and a PLGA compositional ratio from about 75/25 to about 50/50. The microsphere promotes the production of various endogenous repair factors useful against various tissue disorders.
    • 本发明提供了一种在施用后约两周至约四周的缓释期的微球,以使得能够包含更高含量的药物以抑制药物的初始爆发,并保持最佳, 缓释期有效血药浓度。 在含有药物和聚乳酸/乙醇酸(PLGA)共聚物的微球中,每重量份药物的PLGA共聚物的量为约3至约10重量份; 微球的平均粒径为约20至约50μm; 和(3)PLGA共聚物的重均分子量为约10,000至约50,000,PLGA组成比为约75/25至约50/50。 微球促进了各种可用于各种组织疾病的内源性修复因子的产生。