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1. 发明申请

US20050109045A1 Cryostat having an integrated staining station 有权
标题翻译：具有综合染色站的低温恒温器
公开(公告)号：US20050109045A1
公开(公告)日：2005-05-26
申请号：US10991274
申请日：2004-11-17
申请人： Claudia Dorenkamp , Stefan Kuenkel
发明人： Claudia Dorenkamp , Stefan Kuenkel
IPC分类号： B01L1/00 , G01N1/06 , G01N1/28 , G01N1/31 , G01N35/00 , F25B19/00
CPC分类号： G01N1/06 , B01L1/00 , B01L2300/18 , G01N1/31 , G01N2001/2873 , G01N2035/00138
摘要： A cryostat (1) having a sealable housing (2) is described. The housing (2) encloses a coolable cryostat chamber (3), and a refrigeration device (4), a control system (5) and a power supply (6) are provided for cooling the cryostat chamber (3). For cutting frozen samples, a microtome is arranged in the cryostat chamber (3), a staining station (7) being integrated into the housing (2) outside the cryostat chamber (3).
摘要翻译：描述了具有可密封外壳（2）的低温恒温器（1）。壳体（2）包围一个可冷却的低温恒温器室（3），并提供冷藏装置（4），控制系统（5）和电源（6）以冷却低温恒温器室（3）。为了切割冷冻样品，切片机布置在低温恒温室（3）中，染色站（7）整合到低温恒温器室（3）外部的壳体（2）中。

2. 发明授权

US06858183B2 Apparatus for treating objects 有权
标题翻译：用于处理物体的装置
公开(公告)号：US06858183B2
公开(公告)日：2005-02-22
申请号：US09931600
申请日：2001-08-16
申请人： Stefan Thiem , Stefan Kuenkel , Eric Barth
发明人： Stefan Thiem , Stefan Kuenkel , Eric Barth
IPC分类号： G01N33/48 , G01N1/30 , G01N1/31 , G01N1/34 , G01N35/00
CPC分类号： G01N1/31 , G01N2001/315 , Y10T436/11 , Y10T436/112499
摘要： An apparatus for treating objects, in particular cytological or histological specimens, having multiple processing stations and a transport device for delivering the objects into and out of the processing stations, is characterized in that at least one running-water station (1), having an inflow (2) and an outflow (3), is provided as a processing station.
摘要翻译：一种用于处理具有多个处理站的物体（特别是细胞学或组织学标本）的装置，其特征在于，至少一个流水站（1）具有流入（2）和流出（3）作为处理站。

3. 发明申请

US20050109044A1 Cryostat having a heating plate 有权
标题翻译：冷冻机具有加热板
公开(公告)号：US20050109044A1
公开(公告)日：2005-05-26
申请号：US10986681
申请日：2004-11-12
申请人： Claudia Dorenkamp , Stefan Kuenkel
发明人： Claudia Dorenkamp , Stefan Kuenkel
IPC分类号： A01N1/00 , B01L7/00 , B01L9/00 , G01N1/06 , G01N1/28 , G01N1/31 , G01N35/00 , F25B19/00 , F25C5/02
CPC分类号： B01L7/52 , A01N1/00 , B01L9/52 , B01L2300/0822 , B01L2300/1805 , G01N1/06 , G01N1/31 , G01N2001/2873 , G01N2035/00138 , Y10T83/536
摘要： A cryostat (1) having a sealable housing (2) is described, the housing (2) enclosing a coolable cryostat chamber (3). For cooling the cryostat chamber (3), a refrigeration device (4), a control system (5) and a power supply (6) are provided. For cutting frozen samples, a microtome is arranged in the cryostat chamber (3). A temperature-controllable heating plate (7) is integrated into the housing (2) of the cryostat (1), outside the cryostat chamber (3).
摘要翻译：描述了具有可密封壳体（2）的低温恒温器（1），所述壳体（2）包围可冷却的低温恒温器室（3）。为了冷却低温恒温器室（3），设置有制冷装置（4），控制系统（5）和电源（6）。为了切割冷冻样品，切片机布置在低温恒温室（3）中。温度可控的加热板（7）被集成到低温恒温器（1）的壳体（2）内，在低温恒温器室（3）的外部。

4. 发明授权

US08557511B2 Method and apparatus for infiltrating tissue samples with paraffin 有权
标题翻译：用石蜡渗透组织样本的方法和装置
公开(公告)号：US08557511B2
公开(公告)日：2013-10-15
申请号：US12542523
申请日：2009-08-17
申请人： Hermann Ulbrich , Michael Rapp , Marc Konrad , Holger Metzner , Markus Dobusch , Eva Goedecke , Stefan Kuenkel , Udo Herrmann
发明人： Hermann Ulbrich , Michael Rapp , Marc Konrad , Holger Metzner , Markus Dobusch , Eva Goedecke , Stefan Kuenkel , Udo Herrmann
IPC分类号： C12M1/36
CPC分类号： G01N1/31 , G01N1/36
摘要： A method and an apparatus are described for infiltrating tissue samples with carrier material, preferably paraffin. A supply of carrier material is kept ready for use in a supply station. From there, the carrier material can be delivered into at least a first and a second container. In these first and second containers carrier materials of differing degrees of purity are kept ready for use, respectively, for performing various infiltration steps on tissue samples. By means of the described method and apparatus the tissue processor can be operated with as little interruptions as possible and an ease in operation is achieved.
摘要翻译：描述了用载体材料（优选石蜡）渗透组织样品的方法和装置。供应载体材料的供应准备供供应站使用。从那里，载体材料可以被输送到至少第一和第二容器中。在这些第一和第二容器中，不同程度的纯度的载体材料分别保持准备用于在组织样品上进行各种渗透步骤。通过所描述的方法和装置，组织处理器可以以尽可能少的中断进行操作并且实现易于操作。

5. 发明授权

US08071026B2 Tissue Processor 有权
标题翻译：组织处理器
公开(公告)号：US08071026B2
公开(公告)日：2011-12-06
申请号：US12545430
申请日：2009-08-21
申请人： Michael Rapp , Marc Konrad , Markus Dobusch , Stefan Kuenkel
发明人： Michael Rapp , Marc Konrad , Markus Dobusch , Stefan Kuenkel
IPC分类号： G01N21/00
CPC分类号： G01N1/31 , G01N2035/00306 , G01N2035/0498
摘要： A tissue processor is described that comprises a retort for processing histological samples using various reagents, a plurality of exchangeable reagent supply containers that each comprise at least one container opening, a system of conduits, a control device for conveying reagents out of the reagent supply containers through at least one reagent conduit into the retort, and system bottles. The reagent supply containers and the system bottles are connected via the pertinent reagent conduits to at least one valve. The valve is electrically connected to the control device such that at least one of filling and emptying of the system bottles with reagents from the reagent supply containers is controlled. This design allows differently dimensioned reagent supply containers while at the same time minimizing the space requirement for the reagent containers.
摘要翻译：描述了一种组织处理器，其包括用于使用各种试剂处理组织学样品的蒸馏器，多个可更换试剂供应容器，每个可更换试剂供应容器各自包括至少一个容器开口，管道系统，用于将试剂输送出试剂供应容器的控制装置通过进入蒸馏器的至少一个试剂管道和系统瓶子。试剂供应容器和系统瓶通过相关试剂导管连接至至少一个阀。该阀与控制装置电连接，从而控制用来自试剂供应容器的试剂填充和排空系统瓶中的至少一个。该设计允许不同尺寸的试剂供应容器，同时最小化试剂容器的空间要求。

6. 发明申请

US20100055777A1 TISSUE PROCESSOR 有权
标题翻译：组织加工商
公开(公告)号：US20100055777A1
公开(公告)日：2010-03-04
申请号：US12545430
申请日：2009-08-21
申请人： Michael Rapp , Marc Konrad , Markus Dobusch , Stefan Kuenkel
发明人： Michael Rapp , Marc Konrad , Markus Dobusch , Stefan Kuenkel
IPC分类号： C12M1/00
CPC分类号： G01N1/31 , G01N2035/00306 , G01N2035/0498
摘要： A tissue processor is described that comprises a retort for processing histological samples using various reagents, a plurality of exchangeable reagent supply containers that each comprise at least one container opening, a system of conduits, a control device for conveying reagents out of the reagent supply containers through at least one reagent conduit into the retort, and system bottles. The reagent supply containers and the system bottles are connected via the pertinent reagent conduits to at least one valve. The valve is electrically connected to the control device such that at least one of filling and emptying of the system bottles with reagents from the reagent supply containers is controlled. This design allows differently dimensioned reagent supply containers while at the same time minimizing the space requirement for the reagent containers.
摘要翻译：描述了一种组织处理器，其包括用于使用各种试剂处理组织学样品的蒸馏器，多个可更换试剂供应容器，每个可更换试剂供应容器各自包括至少一个容器开口，管道系统，用于将试剂输送出试剂供应容器的控制装置通过进入蒸馏器的至少一个试剂管道和系统瓶子。试剂供应容器和系统瓶通过相关试剂导管连接至至少一个阀。该阀与控制装置电连接，从而控制用来自试剂供应容器的试剂填充和排空系统瓶中的至少一个。该设计允许不同尺寸的试剂供应容器，同时最小化试剂容器的空间要求。

7. 发明申请

US20100055788A1 METHOD AND APPARATUS FOR INFILTRATING TISSUE SAMPLES WITH PARAFFIN 有权
标题翻译：用PARAFFIN浸泡组织样品的方法和装置
公开(公告)号：US20100055788A1
公开(公告)日：2010-03-04
申请号：US12542523
申请日：2009-08-17
申请人： Hermann Ulbrich , Michael Rapp , Marc Konrad , Holger Metzner , Markus Dobusch , Eve Goedecke , Stefan Kuenkel , Udo Herrmann
发明人： Hermann Ulbrich , Michael Rapp , Marc Konrad , Holger Metzner , Markus Dobusch , Eve Goedecke , Stefan Kuenkel , Udo Herrmann
IPC分类号： C12N5/06 , C12M3/00
CPC分类号： G01N1/31 , G01N1/36
摘要： A method and an apparatus are described for infiltrating tissue samples with carrier material, preferably paraffin. A supply of carrier material is kept ready for use in a supply station. From there, the carrier material can be delivered into at least a first and a second container. In these first and second containers carrier materials of differing degrees of purity are kept ready for use, respectively, for performing various infiltration steps on tissue samples. By means of the described method and apparatus the tissue processor can be operated with as little interruptions as possible and an ease in operation is achieved.
摘要翻译：描述了用载体材料（优选石蜡）渗透组织样品的方法和装置。供应载体材料的供应准备供供应站使用。从那里，载体材料可以被输送到至少第一和第二容器中。在这些第一和第二容器中，不同程度的纯度的载体材料分别保持准备用于在组织样品上进行各种渗透步骤。通过所描述的方法和装置，组织处理器可以以尽可能少的中断进行操作并且实现易于操作。

8. 发明授权

US07287388B2 Cryostat having an integrated staining station 有权
标题翻译：具有综合染色站的低温恒温器
公开(公告)号：US07287388B2
公开(公告)日：2007-10-30
申请号：US10991274
申请日：2004-11-17
申请人： Claudia Dorenkamp , Stefan Kuenkel
发明人： Claudia Dorenkamp , Stefan Kuenkel
IPC分类号： F25B19/00 , F25B25/00 , B32B5/02 , B32B27/04 , B01L3/00
CPC分类号： G01N1/06 , B01L1/00 , B01L2300/18 , G01N1/31 , G01N2001/2873 , G01N2035/00138
摘要： A cryostat (1) having a sealable housing (2) is described. The housing (2) encloses a coolable cryostat chamber (3), and a refrigeration device (4), a control system (5) and a power supply (6) are provided for cooling the cryostat chamber (3). For cutting frozen samples, a microtome is arranged in the cryostat chamber (3), a staining station (7) being integrated into the housing (2) outside the cryostat chamber (3).
摘要翻译：描述了具有可密封外壳（2）的低温恒温器（1）。壳体（2）包围一个可冷却的低温恒温器室（3），并提供冷藏装置（4），控制系统（5）和电源（6）以冷却低温恒温器室（3）。为了切割冷冻样品，切片机布置在低温恒温室（3）中，染色站（7）整合到低温恒温器室（3）外部的壳体（2）中。

9. 发明授权

US07240497B2 Cryostat having a heating plate 有权
标题翻译：冷冻机具有加热板
公开(公告)号：US07240497B2
公开(公告)日：2007-07-10
申请号：US10986681
申请日：2004-11-12
申请人： Claudia Dorenkamp , Stefan Kuenkel
发明人： Claudia Dorenkamp , Stefan Kuenkel
IPC分类号： F25B19/00 , F25C5/02 , H05B1/00 , H05B3/00 , A61B18/18 , B26D5/00
CPC分类号： B01L7/52 , A01N1/00 , B01L9/52 , B01L2300/0822 , B01L2300/1805 , G01N1/06 , G01N1/31 , G01N2001/2873 , G01N2035/00138 , Y10T83/536
摘要： A cryostat (1) having a sealable housing (2) is described, the housing (2) enclosing a coolable cryostat chamber (3). For cooling the cryostat chamber (3), a refrigeration device (4), a control system (5) and a power supply (6) are provided. For cutting frozen samples, a microtome is arranged in the cryostat chamber (3). A temperature-controllable heating plate (7) is integrated into the housing (2) of the cryostat (1), outside the cryostat chamber (3).
摘要翻译：描述了具有可密封壳体（2）的低温恒温器（1），所述壳体（2）包围可冷却的低温恒温器室（3）。为了冷却低温恒温器室（3），设置有制冷装置（4），控制系统（5）和电源（6）。为了切割冷冻样品，切片机布置在低温恒温室（3）中。温度可控的加热板（7）被集成到低温恒温器（1）的壳体（2）内，在低温恒温器室（3）的外部。

10. 发明授权

US06756015B2 Apparatus for treating objects 有权
标题翻译：用于处理物体的装置
公开(公告)号：US06756015B2
公开(公告)日：2004-06-29
申请号：US09931138
申请日：2001-08-16
申请人： Charilaos Dalkidis , Stefan Kuenkel , Ralf Eckert , Stefan Thiem
发明人： Charilaos Dalkidis , Stefan Kuenkel , Ralf Eckert , Stefan Thiem
IPC分类号： G01N1506
CPC分类号： G01N1/31 , G01N2001/315 , Y10T436/112499
摘要： An apparatus for treating objects, in particular cytological or histological specimens, having multiple processing stations and preferably a transport device for delivering the objects into and out of the processing stations, is characterized in that at least one heatable reagent station (1) is provided as a processing station.
摘要翻译：用于处理具有多个处理站的物体，特别是细胞学或组织学标本的装置，其特征在于，至少一个可加热试剂台（1）被设置为一个处理站。

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