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1. 发明授权

US08095216B1 System to create arbitrary waveforms using an external inductor and an implantable medical device 有权
标题翻译：使用外部电感和可植入医疗设备创建任意波形的系统
公开(公告)号：US08095216B1
公开(公告)日：2012-01-10
申请号：US11858365
申请日：2007-09-20
申请人： J. Christopher Moulder , Scott Salys
发明人： J. Christopher Moulder , Scott Salys
IPC分类号： A61N1/362
CPC分类号： A61N1/3956 , A61N1/3906 , A61N1/3912
摘要： An implantable stimulation system includes a stimulation current generator encased in an implantable housing, one or more stimulation leads to deliver therapeutic stimulation from the generator to target patient tissue, and inductive elements arranged to condition the stimulation for delivery to the target tissue with increased efficiency and reduced pain sensation. The inductive elements are arranged external to the housing and integral with one or more of a stimulation lead or an external component of the housing, such as a header. The inductive elements serve to condition therapeutic stimulations such that varying the output of the generator allows the system to deliver arbitrary effective waveforms to the target tissue.
摘要翻译：可植入刺激系统包括封装在可植入壳体中的刺激电流发生器，一个或多个刺激引线，用于将治疗刺激从发生器传递到目标患者组织;以及感应元件，被布置成调节刺激以提高效率输送到目标组织，减轻疼痛感。电感元件布置在壳体的外部并与外壳的一个或多个刺激引线或外部部件（例如插头）成一体。电感元件用于调节治疗刺激，使得改变发生器的输出允许系统向目标组织传送任意有效波形。

2. 发明授权

US07558632B1 Method of manufacturing an implantable J-shaped lead 有权
标题翻译：可植入J型引线的制造方法
公开(公告)号：US07558632B1
公开(公告)日：2009-07-07
申请号：US11459315
申请日：2006-07-21
申请人： Scott Salys
发明人： Scott Salys
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An implantable multi-conductor endocardial lead for a cardiac stimulator includes a tubular lead body of flexible resilient insulative material having a first lumen and a smaller diameter tubular member of similar material having a second lumen is coaxially received in the first lumen. An outer coil conductor is received within an annular cavity between the tubular lead body and the tubular member. An elongated inner coil conductor is received within the second lumen. A tip electrode at the distal end of the lead is coupled to the inner coil conductor and a ring electrode proximally spaced from the tip electrode is coupled to the outer coil conductor. All components except for the outer coil conductor have a normally straight configuration and the outer coil conductor is pre-shaped into a generally circular looped configuration such that, upon assembly, the resulting endocardial lead results in a J-configuration at its distal end.
摘要翻译：用于心脏刺激器的可植入多导体心内膜包括具有第一管腔的柔性弹性绝缘材料的管状引线本体和具有第二内腔的类似材料的较小直径管状构件同轴地容纳在第一管腔中。外部线圈导体容纳在管状引线主体和管状构件之间的环形空腔内。细长的内部线圈导体被容纳在第二内腔内。在引线的远端处的尖端电极耦合到内部线圈导体，并且与尖端电极向近侧间隔开的环形电极耦合到外部线圈导体。除了外部线圈导体之外的所有部件具有通常的直线构造，并且外部线圈导体被预成形为大致圆形的环形构造，使得在组装时，所得到的心内膜导线在其远端处导致J形结构。

3. 发明申请

US20130012824A1 CORONARY VENOUS SYSTEM PRESSURE SENSING 审中-公开
标题翻译：冠状静脉系统压力感测
公开(公告)号：US20130012824A1
公开(公告)日：2013-01-10
申请号：US13614620
申请日：2012-09-13
申请人： Guy Vanney , Scott Salys , Thao Ngo , Elizabeth Nee , Annapurna Karicherla , Ravisankar Gurusamy , Gene A. Bornzin
发明人： Guy Vanney , Scott Salys , Thao Ngo , Elizabeth Nee , Annapurna Karicherla , Ravisankar Gurusamy , Gene A. Bornzin
IPC分类号： A61B5/0215
CPC分类号： A61B5/02158 , A61N1/3627 , A61N1/36564 , A61N1/395 , A61N2001/0585
摘要： Disclose herein is a method of measuring pressures in a coronary sinus. In one embodiment, the method includes: introducing a distal portion of a lead or tool into the coronary sinus, wherein the distal portion includes first and second pressure sensors and at least one selectably expandable member; expanding the at least one expandable member such that the first and second sensors are isolated from each other within the coronary sinus; and taking pressure measurements with the first and second sensors when isolated from each other.
摘要翻译：这里公开的是测量冠状窦压力的方法。在一个实施例中，该方法包括：将引导件或工具的远端部分引入冠状窦，其中远端部分包括第一和第二压力传感器和至少一个可选择地可扩张的构件; 膨胀所述至少一个可膨胀构件，使得所述第一和第二传感器在所述冠状窦内彼此隔离; 并且当彼此隔离时，利用第一和第二传感器进行压力测量。

4. 发明申请

US20100331942A1 MRI COMPATIBLE IMPLANTABLE MEDICAL LEAD AND METHOD OF MAKING SAME 审中-公开
标题翻译： MRI兼容可植入医疗用铅及其制造方法
公开(公告)号：US20100331942A1
公开(公告)日：2010-12-30
申请号：US12493984
申请日：2009-06-29
申请人： Martin Cholette , Scott Salys
发明人： Martin Cholette , Scott Salys
IPC分类号： A61N1/05 , H01R43/00
CPC分类号： A61N1/0563 , A61N1/086 , H01R2201/12 , Y10T29/49117
摘要： An implantable medical lead is disclosed herein. The implantable medical lead may include a body including an electrical insulation tube, a distal portion with an electrode, and a proximal portion with a lead connector end. The electrical insulation tube may be coaxial with a longitudinally extending center axis of the body. The lead may also include an electrical pathway extending between the electrode and lead connector end, the electrical pathway including an inductor comprising an electrical conductor helically wound directly on an outer circumferential surface of the insulation tube.
摘要翻译：本文公开了可植入医疗引线。可植入医疗引线可以包括主体，其包括电绝缘管，具有电极的远端部分和具有引线连接器端部的近端部分。电绝缘管可以与主体的纵向延伸的中心轴线同轴。引线还可以包括在电极和引线连接器端之间延伸的电通路，电路包括电感器，该电感器包括直接螺旋缠绕在绝缘管的外圆周表面上的电导体。

5. 发明申请

US20110218602A1 BRAIDED IMPLANTABLE MEDICAL LEAD AND METHOD OF MAKING SAME 审中-公开
标题翻译：可植入式医用引线及其制造方法
公开(公告)号：US20110218602A1
公开(公告)日：2011-09-08
申请号：US12716519
申请日：2010-03-03
申请人： Greg Kampa , Dorab N. Sethna , Scott Salys , Keith Victorine
发明人： Greg Kampa , Dorab N. Sethna , Scott Salys , Keith Victorine
IPC分类号： A61N1/05 , H01R43/00
CPC分类号： A61N1/05 , H01R43/00 , Y10T29/4921
摘要： An implantable medical lead disclosed herein may include a longitudinally extending body, a helical anchor and a lead connector end. The longitudinally extending body may include a distal end, a proximal end, a braid-reinforced inner tubular layer extending between the proximal and distal ends, and an outer tubular layer extending between the proximal and distal ends. The braid-reinforced inner tubular layer may extend through the outer tubular layer in a coaxial arrangement. The helical anchor electrode may be operably coupled to a distal end of the braid-reinforced inner tubular layer. The lead connector end may be operably coupled to the proximal end of the body and include a pin contact operably coupled to a proximal end of the braid-reinforced tubular layer. Rotation of the pin contact relative to the lead connector end may cause rotation of the braid-reinforced inner tubular layer within the outer tubular layer, and the resulting rotation of the braid-reinforced inner tubular layer may cause rotation of the helical anchor electrode.
摘要翻译：本文公开的可植入医疗引线可以包括纵向延伸体，螺旋锚和引线连接器端。纵向延伸体可以包括远端，近端，在近端和远端之间延伸的编织增强的内管状层，以及在近端和远端之间延伸的外管层。编织增强的内部管状层可以以同轴布置延伸穿过外部管状层。螺旋锚定电极可以可操作地联接到编织物增强的内部管状层的远端。引导连接器端可以可操作地耦合到主体的近端，并且包括可操作地联接到编织增强管状层的近端的销接触。销触点相对于引线连接器端部的旋转可能导致编织增强的内部管状层在外部管状层内的旋转，并且编织增强的内部管状层的最终旋转可能导致螺旋锚定电极的旋转。

6. 发明授权

US07890190B1 Deflectable hollow stylet guidewire system 有权
标题翻译：可偏转中空管心针导丝系统
公开(公告)号：US07890190B1
公开(公告)日：2011-02-15
申请号：US11677006
申请日：2007-02-20
申请人： Scott Salys , Ravi Jain
发明人： Scott Salys , Ravi Jain
IPC分类号： A61N1/00
CPC分类号： A61N1/056
摘要： A body implantable lead system includes an over-the-wire lead with a longitudinally extending lumen. A hollow stylet having an outer peripheral surface is introduced into the lumen and an annular resilient blood seal within the lumen may be sealingly positioned between the outer peripheral surface of the stylet and the lead to prevent flow of blood beyond the blood seal and into the lumen in a proximal direction. A guidewire is slidably received within the hollow stylet and includes a tip end which may project through the passage at the distal end of the lead such that relative movement of the guidewire and stylet within the lead is enabled while avoiding friction between the blood seal and the guidewire. Either the guidewire or the stylet may be preshaped for proper placement of the lead for engagement with the body tissue and surrounded by a semi-rigid retractable sheath.
摘要翻译：身体可植入引线系统包括具有纵向延伸管腔的线上导线。具有外周面的中空管心针被引入内腔，并且内腔内的环形弹性血液密封件可以密封地定位在探针的外周表面和引线之间，以防止血液流过血液密封件流入腔内在近端方向。引导线可滑动地容纳在中空管心针内，并且包括可以在引线的远端处突出通过通道的尖端，使得导线和探针在引线内的相对运动得以实现，同时避免血液密封和导丝。引导线或探针可以被预先成形，以便正确地放置引线以与身体组织接合并且被半刚性的可缩回护套包围。

7. 发明申请

US20100318019A1 ELECTROPHYSIOLOGY DEVICES EMPLOYING ELECTRICALLY CONDUCTIVE POLYMER CONDUCTORS AND METHODS OF MANUFACTURING SUCH DEVICES 审中-公开
标题翻译：使用电导电聚合物导体的电生理装置及其制造方法
公开(公告)号：US20100318019A1
公开(公告)日：2010-12-16
申请号：US12484539
申请日：2009-06-15
申请人： Elizabeth Nee , Scott Salys , Greg Kampa
发明人： Elizabeth Nee , Scott Salys , Greg Kampa
IPC分类号： A61N1/05 , H01B3/44 , A61N1/30 , A61M25/00
CPC分类号： A61N1/05 , A61M25/0012 , A61M2025/0034 , A61M2025/004 , H01B3/28 , H01B3/302 , H01B3/46 , Y10T29/49117
摘要： A medical tubular body that may be used in an implantable medical lead, a catheter, a sheath and introducer is disclosed herein. The medical tubular body may include a tubular layer formed of an electrically insulating polymer and an electrically conductive polymer strip imbedded in and longitudinally extending through the insulating polymer.
摘要翻译：本文公开了可用于可植入医疗引线，导管，护套和导引器中的医疗管状体。医疗管状体可以包括由电绝缘聚合物形成的管状层和嵌入并纵向延伸穿过绝缘聚合物的导电聚合物带。

8. 发明授权

US08751018B1 Implantable lead and method of making the same 有权
标题翻译：可植入铅及其制作方法
公开(公告)号：US08751018B1
公开(公告)日：2014-06-10
申请号：US11855064
申请日：2007-09-13
申请人： Dorab N. Sethna , Keith Victorine , Scott Salys
发明人： Dorab N. Sethna , Keith Victorine , Scott Salys
IPC分类号： A61N1/05
CPC分类号： A61N1/05
摘要： A method of manufacturing an implantable lead includes providing a core including at least one longitudinal lumen; providing a jacket comprising a reflowable material; positioning the core at least partially within the jacket; and, after positioning, applying heat to cause the material of the jacket to reflow and bond to the core. An implantable lead includes a core including at least one longitudinal lumen; and a jacket comprising a reflowable material. The core may be at least partially disposed within the jacket with the material of the jacket reflow-bonded to the core. The implantable lead may further include at least one lead component associated with at least one of the core and the jacket.
摘要翻译：制造可植入引线的方法包括提供包括至少一个纵向内腔的芯; 提供包括可回流材料的护套; 将芯部至少部分地定位在护套内; 并且在定位之后，施加热量以使夹套的材料回流并结合到芯部。可植入引线包括：芯，其包括至少一个纵向内腔; 以及包括可回流材料的护套。芯可以至少部分地设置在护套内，套管的材料回流焊接到芯上。可植入引线还可以包括至少一个与芯和护套中的至少一个相关联的引线部件。

9. 发明申请

US20090276020A1 TOOLS FOR DELIVERING IMPLANTABLE MEDICAL LEADS AND METHODS OF USING AND MANUFACTURING SUCH TOOLS 审中-公开
标题翻译：用于提供可植入医疗领域的工具以及使用和制造这些工具的方法
公开(公告)号：US20090276020A1
公开(公告)日：2009-11-05
申请号：US12114616
申请日：2008-05-02
申请人： Elizabeth Nee , Thao Thu Nguyen , Scott Salys
发明人： Elizabeth Nee , Thao Thu Nguyen , Scott Salys
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61B5/0002 , A61B5/042 , A61B5/06 , A61B5/062
摘要： Disclosed herein is a tool for implanting a medical lead. In one embodiment, the tool includes a body, an electrode, and a conductor. The body includes a distal end and a proximal end. The electrode is supported by the body. The conductor is in electrical contact with the electrode and extends along the body from the electrode to the proximal end. The electrode and conductor form an electrically conductive path that extends from a surface of the electrode to a proximal most point of the conductor on the body. The electrical resistance of the electrically conductive path is at least approximately 100 Ohms.
摘要翻译：这里公开了用于植入医疗引线的工具。在一个实施例中，该工具包括主体，电极和导体。主体包括远端和近端。电极由身体支撑。导体与电极电接触并沿主体从电极延伸到近端。电极和导体形成从电极的表面延伸到主体上的导体的最近点的导电路径。导电路径的电阻至少约为100欧姆。

10. 发明授权

US07164950B2 Implantable stimulation device with isolating system for minimizing magnetic induction 有权
标题翻译：具有隔离系统的植入式刺激装置，用于最小化磁感应
公开(公告)号：US07164950B2
公开(公告)日：2007-01-16
申请号：US10285241
申请日：2002-10-30
申请人： Mark W. Kroll , Scott Salys , Timothy J. Cox , Kerwyn Schimke
发明人： Mark W. Kroll , Scott Salys , Timothy J. Cox , Kerwyn Schimke
IPC分类号： A61N1/372
CPC分类号： A61N1/3718 , A61N1/368
摘要： An implantable cardiac stimulation device is equipped with an isolation system capable of attenuating or eliminating induction currents flowing through the stimulation device by eliminating induction loops. The isolation system comprises a magnetic insulator configured to shield selected components of the stimulation device from external magnetic fields or radio-frequency (RF) signals. The magnetic insulator comprises a plurality of sensors that are configured to detect the intensity of the external magnetic fields and/or RF signals, and a switch bank that electrically isolates certain components of the stimulation device to eliminate the induction loops. The isolation system further comprises an attenuation system comprised of at least one magnetoresistor disposed along potential induction loops to attenuate induction currents when subjected to undesirable external magnetic fields and/or RF signals.
摘要翻译：可植入心脏刺激装置配备有能够通过消除感应环来衰减或消除流过刺激装置的感应电流的隔离系统。隔离系统包括被配置为将刺激装置的选定部件从外部磁场或射频（RF）信号屏蔽的磁性绝缘体。磁绝缘体包括被配置为检测外部磁场和/或RF信号的强度的多个传感器，以及电隔离刺激装置的某些部件以消除感应环的开关组。隔离系统还包括衰减系统，该衰减系统包括至少一个沿电势感应环设置的磁电阻，以在受到不期望的外部磁场和/或RF信号时衰减感应电流。

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