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    • 3. 发明申请
    • ELECTRONIC CONTROL SYSTEMS FOR MARINE VESSELS
    • 海运船用电子控制系统
    • US20070293993A9
    • 2007-12-20
    • US11250601
    • 2005-10-17
    • Dennis GrahamDaniel CarrScott KernHoward Lang
    • Dennis GrahamDaniel CarrScott KernHoward Lang
    • G05D1/00
    • B63H21/21B63H21/213B63H21/22Y10T477/20
    • A control system for a marine vessel having one or more engines and a transmission associated with each engine is disclosed. The control system includes one or more control stations, each having a control arm and arm position means coupled to the control arm for providing an electrical signal that represents a position of the control arm within its operating range. The system includes one or more electronic control units, each of which is electro-mechanically coupled to an engine and a transmission. A first electronic control unit (ECU) includes input means for receiving the electrical signal, control means for controlling a throttle of a first engine and shift position of a first transmission based on the electrical signal, and output means for providing a control signal that represents a current position of the control arm to a second ECU. The second ECU is coupled to the first ECU via the communications link, and includes input means for receiving the control signal from the first ECU, and control means for controlling the throttle of a second engine and the shift position of a second transmission based on the power train control signal.
    • 公开了一种用于具有一个或多个发动机和与每个发动机相关联的变速器的船舶的控制系统。 控制系统包括一个或多个控制站,每个控制站具有控制臂和臂位置装置,其耦合到控制臂,用于提供表示控制臂在其工作范围内的位置的电信号。 该系统包括一个或多个电子控制单元,每个电子控制单元电机械耦合到发动机和变速器。 第一电子控制单元(ECU)包括用于接收电信号的输入装置,用于基于电信号控制第一发动机的节气门和第一变速器的换档位置的控制装置,以及用于提供表示 控制臂的当前位置到第二ECU。 第二ECU经由通信链路耦合到第一ECU,并且包括用于接收来自第一ECU的控制信号的输入装置,以及用于控制第二发动机的节气门的控制装置和基于所述第二ECU的变速位置 动力传动系控制信号。
    • 8. 发明申请
    • Fanc gene mutations in cancer
    • Fanc基因突变在癌症
    • US20060183122A1
    • 2006-08-17
    • US10540904
    • 2003-12-26
    • Scott KernMichael Van Der Heijden
    • Scott KernMichael Van Der Heijden
    • C12Q1/68
    • C07K14/47C12Q1/6886C12Q2600/106C12Q2600/136C12Q2600/156
    • The present invention relates to methods of determining if a patient has cancer or is at increased risk of developing cancer, particularly pancreatic cancer, the method comprising testing a FANC gene for the presence of a cancer-associated coding change, wherein said presence of one or more cancer-associated coding changes is indicative of cancer or an increased risk of cancer in said patient. The invention further relates to methods of treating a patient having cancer, particularly pancreatic cancer, who has one or more cancer-associated coding changes in the FANC genes comprising the step of administering a therapeutically effective amount of a chemotherapeutic cross-linking agent.
    • 本发明涉及确定患者是否患有癌症或具有发展为癌症,特别是胰腺癌的风险增加的方法,所述方法包括测试FANC基因以存在癌症相关编码变化,其中所述存在一种或多种 更多的癌症相关的编码变化是所述患者中的癌症或增加的癌症风险的指示。 本发明还涉及治疗患有癌症的患者,特别是胰腺癌的方法,所述患者在FANC基因中具有一种或多种与癌症相关的编码变化,包括给予治疗有效量的化学治疗性交联剂的步骤。