专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09309312B2 Immunoassay method for human CXCL1 protein 有权
标题翻译：人类CXCL1蛋白免疫测定法
公开(公告)号：US09309312B2
公开(公告)日：2016-04-12
申请号：US13126877
申请日：2009-10-29
申请人： Satoko Kanamori , Giman Jung , Yoshinori Tanaka , Aiko Takayama
发明人： Satoko Kanamori , Giman Jung , Yoshinori Tanaka , Aiko Takayama
IPC分类号： C07K16/24 , G01N33/68 , G01N33/543 , G01N33/563 , A61K39/00
CPC分类号： C07K16/24 , A61K2039/505 , C07K2317/34 , C07K2317/565 , C07K2317/76 , G01N33/543 , G01N33/6857 , G01N33/6863 , G01N2333/522
摘要： An object of the present invention is to detect a human CXCL1 protein with high sensitivity. An immunoassay method is provided for a human CXCL1 protein, by which human CXCL1 or a fragment thereof in a sample is measured using two or more types of anti-human CXCL1 monoclonal antibodies or fragments thereof, wherein: each of the two or more types of anti-human CXCL1 monoclonal antibodies or fragments thereof specifically recognizes any one of sequence regions of the amino acid sequences shown in SEQ ID NOS: 1-3, which are partial sequences of the amino acid sequence composing a human CXCL1 protein; and the two or more types of anti-human CXCL1 monoclonal antibodies or fragments thereof specifically recognize sequence regions that differ from each other. Monoclonal antibodies or fragments thereof are provided, each of which specifically recognizes any one sequence region of the amino acid sequences shown in SEQ ID NOS: 1-3 and has a new amino acid sequence.
摘要翻译：本发明的目的是高灵敏度地检测人CXCL1蛋白。提供了人CXCL1蛋白的免疫测定方法，通过该方法，使用两种或更多种抗人CXCL1单克隆抗体或其片段测量样品中的人CXCL1或其片段，其中：所述两种或更多种类型的抗人CXCL1单克隆抗体或其片段特异性识别作为构成人CXCL1蛋白的氨基酸序列的部分序列的SEQ ID NO：1-3所示的氨基酸序列的任何一个序列区域; 两种以上抗人CXCL1单克隆抗体或其片段特异性识别彼此不同的序列区。提供了单克隆抗体或其片段，其各自特异性识别SEQ ID NO：1-3所示的氨基酸序列的任何一个序列区，并具有新的氨基酸序列。

2. 发明申请

US20130330787A1 METHOD FOR PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION 有权
标题翻译：通过连续发酵生产化学品的方法
公开(公告)号：US20130330787A1
公开(公告)日：2013-12-12
申请号：US13992443
申请日：2011-12-08
申请人： Satoko Kanamori , Jihoon Cheon , Takashi Mimitsuka , Norihiro Takeuchi , Makoto Nishida , Yuji Tanaka
发明人： Satoko Kanamori , Jihoon Cheon , Takashi Mimitsuka , Norihiro Takeuchi , Makoto Nishida , Yuji Tanaka
IPC分类号： C12P13/08 , C12P7/56
CPC分类号： C12P13/08 , C12M29/02 , C12M29/18 , C12M33/14 , C12M41/40 , C12M47/10 , C12P7/40 , C12P7/56 , C12P13/001 , C12P13/04
摘要： A method produces a chemical through continuous fermentation including: (a) culturing a cell in a culture medium in a fermentor to ferment a feedstock to produce a chemical; (b) conducting filtration of the culture medium with a separation membrane module; (c) separating a permeate containing the chemical from the culture medium while retaining a non-permeated liquid in the fermentor, and (d) supplying a gas from at least one of a lower portion of the separation membrane module and a pipe communicating between the fermentor and the separation membrane module to adjust a gas linear velocity in the separation membrane module to 0.15 cm/s to 70 cm/s while supplying the separation membrane module with a liquid.
摘要翻译：方法通过连续发酵生产化学品，包括：（a）在发酵罐中培养培养基中的细胞以发酵原料以生产化学品; （b）用分离膜组件对培养基进行过滤; （c）将含有化学物质的渗透物从培养基中分离，同时将不渗透的液体保持在发酵罐中，和（d）从分离膜组件的下部中的至少一个供给气体，发酵罐和分离膜组件，将分离膜组件中的气体线速度调节至0.15厘米/秒至70厘米/秒，同时向分离膜组件供应液体。

3. 发明申请

US20130302882A1 METHOD FOR STERILIZING SEPARATION MEMBRANE MODULES, STERILIZATION DEVICE, AND APPARATUS FOR PRODUCING CHEMICALS 审中-公开
标题翻译：灭菌分离膜模块灭菌方法，灭菌装置及生产化学品的装置
公开(公告)号：US20130302882A1
公开(公告)日：2013-11-14
申请号：US13997094
申请日：2011-12-22
申请人： Makoto Nishida , Masahiro Henmi , Norihiro Takeuchi , Satoko Kanamori , Jihoon Cheon
发明人： Makoto Nishida , Masahiro Henmi , Norihiro Takeuchi , Satoko Kanamori , Jihoon Cheon
IPC分类号： A61L2/04
CPC分类号： A61L2/04 , B01D65/022 , B01D71/024 , B01D2321/08
摘要： A method of sterilizing a separation membrane module reduces damage of a ceramic separation membrane, a sterilization process device achieves the method of sterilizing, and an apparatus produces chemicals. The method of sterilizing the separation membrane module includes a ceramic-containing separation membrane including a temperature raise step of raising the temperature of the separation membrane module to a predetermined sterilization temperature by feeding sterilization water having a controlled temperature and pressure so that a rate of temperature change of the separation membrane module is 6.0° C. or less per minute, and a sterilization step of sterilizing the separation membrane module at a predetermined temperature for a predetermined time.
摘要翻译：对分离膜组件进行灭菌的方法减少了陶瓷分离膜的损伤，灭菌处理装置实现了灭菌方法，并且设备产生化学品。对分离膜组件进行灭菌的方法包括：含陶瓷分离膜，其包括通过供给具有受控温度和压力的灭菌水将分离膜组件的温度升高到预定灭菌温度的升温步骤，使得温度分离膜组件的改变为每分钟6.0℃或更低，以及在预定温度下将分离膜组件灭菌预定时间的灭菌步骤。

4. 发明申请

US20130266991A1 METHOD FOR PRODUCING CONCENTRATED AQUEOUS SUGAR SOLUTION 审中-公开
标题翻译：生产浓缩水溶性糖溶液的方法
公开(公告)号：US20130266991A1
公开(公告)日：2013-10-10
申请号：US13991686
申请日：2011-12-07
申请人： Satoko Kanamori , Masayuki Hanakawa , Hiroyuki Kurihara , Norihiro Takeuchi , Atsushi Minamino
发明人： Satoko Kanamori , Masayuki Hanakawa , Hiroyuki Kurihara , Norihiro Takeuchi , Atsushi Minamino
IPC分类号： C12P19/14 , C12P7/14
CPC分类号： C12P19/14 , B01D61/025 , B01D61/145 , B01D61/147 , B01D61/16 , B01D61/58 , B01D2311/04 , B01D2311/06 , B01D2311/25 , C12N1/38 , C12P7/10 , C12P7/14 , C13K1/04 , C13K13/002 , Y02E50/16 , B01D2311/2634
摘要： A method produces a concentrated aqueous sugar solution using a cellulose-containing biomass as a raw material, including: (1) hydrolyzing a cellulose-containing biomass to produce an aqueous sugar solution; (2) filtering the aqueous sugar solution obtained in (1) through a microfiltration membrane and/or an ultrafiltration membrane, and recovering an aqueous sugar solution from the permeate side; and (3) filtering the aqueous sugar solution obtained in (2) through a reverse osmosis membrane, recovering a permeate from the permeate side and recovering a concentrated aqueous sugar solution from the feed side; wherein at least a part of the permeate from the reverse osmosis membrane is used as a hydrothermal treatment liquid, biomass-suspending, liquid, enzyme-diluting liquid, acid-diluting liquid and/or alkali-diluting liquid in (1).
摘要翻译：一种方法使用含纤维素的生物质作为原料产生浓缩的糖水溶液，其包括：（1）水解含纤维素的生物质以产生糖水溶液; （2）通过微滤膜和/或超滤膜过滤由（1）得到的糖水溶液，从渗透侧回收糖溶液; （3）通过反渗透膜过滤（2）得到的糖水溶液，从渗透侧回收渗透物，从进料侧回收浓缩的糖水溶液; 其中来自反渗透膜的渗透物的至少一部分在（1）中用作水热处理液，生物质悬浮液，液体，酶稀释液，酸稀释液和/或碱稀释液。

5. 发明申请

US20120329074A1 MARKER FOR DETECTING GASTRIC CANCER AND METHOD FOR DETECTING GASTRIC CANCER 有权
标题翻译：用于检测胃癌的标记物和用于检测胃癌的方法
公开(公告)号：US20120329074A1
公开(公告)日：2012-12-27
申请号：US13582316
申请日：2011-03-03
申请人： Yoshinori Tanaka , Satoko Kanamori , Michimoto Kobayashi , Giman Jung , Yoshiharu Sakai , Hiroshi Okabe
发明人： Yoshinori Tanaka , Satoko Kanamori , Michimoto Kobayashi , Giman Jung , Yoshiharu Sakai , Hiroshi Okabe
IPC分类号： G01N33/574
CPC分类号： G01N33/57446 , G01N2333/4712
摘要： It is intended to provide a method for detecting gastric cancer, which is low invasive to a human test subject and has high detection sensitivity and accuracy. The present invention provides a method comprising measuring in vitro the amount of COTL1 protein, a variant thereof, and/or a fragment thereof in a body fluid sample derived from a human test subject, and detecting the presence or absence of gastric cancer affecting the test subject on the basis of the amount, and a kit for gastric cancer diagnosis comprising an antibody capable of specifically binding to the protein.
摘要翻译：目的在于提供一种检测对人体检测对象侵袭性低，检测灵敏度高，准确度高的胃癌的方法。本发明提供了一种方法，其包括在源自人类受检者的体液样品中体外测量COTL1蛋白，其变体和/或其片段的量，并检测影响测试的胃癌的存在或不存在基于该量的受试者，以及包含能够特异性结合蛋白质的抗体的胃癌诊断试剂盒。

6. 发明申请

US20130280773A1 METHOD FOR PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION 审中-公开
标题翻译：通过连续发酵生产化学品的方法
公开(公告)号：US20130280773A1
公开(公告)日：2013-10-24
申请号：US13996241
申请日：2011-12-21
申请人： Norihiro Takeuchi , Jihoon Cheon , Makoto Nishida , Satoko Kanamori , Atsushi Kobayashi
发明人： Norihiro Takeuchi , Jihoon Cheon , Makoto Nishida , Satoko Kanamori , Atsushi Kobayashi
IPC分类号： C12P7/56
CPC分类号： C12P7/56 , C12M29/04 , C12M33/14
摘要： A method of producing a chemical includes a fermentation step that converts a fermentation feedstock, through fermentation by culturing a microorganism or culture cells, into a fermented liquid containing the chemical, and a membrane separation step that collects the chemical, as a filtrate, from the fermented liquid with the use of two or more separation membrane modules, and returning the non-filtered liquid to the fermented liquid, wherein in the membrane separation step, timing of the filtration-stop treatment for each separation membrane module is controlled when an intermittent filtration operation including alternately repeating a filtration treatment and a filtration-stop treatment is performed with plural separation membrane modules.
摘要翻译：制造化学品的方法包括发酵步骤，其通过将微生物或培养细胞培养发酵成发酵液，将发酵原料转化成含有该化学品的发酵液，以及膜分离步骤，将滤液中的化学物质从使用两个或更多个分离膜组件的发酵液体，并将未过滤的液体返回到发酵液中，其中在膜分离步骤中，当间歇过滤时，控制每个分离膜组件的过滤停止处理的时间用多个分离膜组件进行交替重复过滤处理和过滤停止处理的操作。

7. 发明授权

US09127054B2 Immunoassay of cofilin 1 protein 有权
标题翻译： cofilin 1蛋白的免疫测定
公开(公告)号：US09127054B2
公开(公告)日：2015-09-08
申请号：US13992567
申请日：2011-12-05
申请人： Michimoto Kobayashi , Yoshinori Tanaka , Aiko Takayama , Satoko Kanamori , Giman Jung , Yoshiharu Sakai , Hiroshi Okabe
发明人： Michimoto Kobayashi , Yoshinori Tanaka , Aiko Takayama , Satoko Kanamori , Giman Jung , Yoshiharu Sakai , Hiroshi Okabe
IPC分类号： C07K16/18 , G01N33/577 , G01N33/574
CPC分类号： C07K16/18 , C07K2317/34 , G01N33/57446 , G01N33/577
摘要： An object of the present invention is to realize an antibody or a fragment thereof specifically recognizing a cofilin 1 protein, and a method for detecting and testing gastrointestinal cancer with high detection performance, which comprises performing immunoassay of the cofilin 1 protein using the antibody or a fragment thereof. An immunoassay of cofilin 1 protein is characterized by measuring cofilin 1 or a fragment thereof in a sample using 2 or more types of anti-cofilin 1 monoclonal antibody or fragments thereof specifically recognizing different peptide regions in the amino acid sequence constituting the cofilin 1 protein.
摘要翻译：本发明的目的是实现特异性识别椰子蛋白1蛋白的抗体或其片段，以及检测和检测具有高检测性能的胃肠癌的方法，其包括使用抗体或免疫球蛋白进行免疫测定片段。使用两种或更多种类型的抗-cofilin1单克隆抗体或其片段特异性识别构成所述辅酶1蛋白的氨基酸序列中的不同肽区域的方法，对样品中的菲菲林1或其片段进行测定。

8. 发明申请

US20140308712A1 METHOD FOR PRODUCING CONCENTRATED AQUEOUS SUGAR SOLUTION 审中-公开
标题翻译：生产浓缩水溶性糖溶液的方法
公开(公告)号：US20140308712A1
公开(公告)日：2014-10-16
申请号：US13991703
申请日：2011-12-07
申请人： Masayuki Hanakawa , Satoko Kanamori , Hiroyuki Kurihara , Norihiro Takeuchi , Atsushi Minamino
发明人： Masayuki Hanakawa , Satoko Kanamori , Hiroyuki Kurihara , Norihiro Takeuchi , Atsushi Minamino
IPC分类号： C13K1/04
CPC分类号： C13K1/04 , B01D61/022 , B01D61/025 , B01D61/027 , B01D61/142 , B01D61/145 , B01D61/147 , B01D61/16 , B01D61/58 , B01D65/02 , B01D2311/06 , B01D2311/25 , B01D2321/12 , C12P19/02 , C12P19/14 , C13K13/002
摘要： A method produces a concentrated aqueous sugar solution using a cellulose-containing biomass as a raw material, including: (1) hydrolyzing a cellulose-containing biomass to produce an aqueous sugar solution; (2) filtering the aqueous sugar solution obtained in (1) through a microfiltration membrane and/or an ultrafiltration membrane, and recovering an aqueous sugar solution from the permeate side; and (3) filtering the aqueous sugar solution obtained in (2) through a nanofiltration membrane and/or a reverse osmosis membrane, recovering a permeate from the permeate side and recovering a concentrated aqueous sugar solution from the feed side; wherein at least a part of the permeate from the nanofiltration membrane and/or the reverse osmosis membrane is used as a washing liquid in (1) and/or (2).
摘要翻译：一种方法使用含纤维素的生物质作为原料产生浓缩的糖水溶液，其包括：（1）水解含纤维素的生物质以产生糖水溶液; （2）通过微滤膜和/或超滤膜过滤由（1）得到的糖水溶液，从渗透侧回收糖溶液; （3）通过纳滤膜和/或反渗透膜过滤（2）得到的糖水溶液，从渗透侧回收渗透物质，从进料侧回收浓缩的糖水溶液; 其中，在（1）和/或（2）中使用来自所述纳滤膜和/或反渗透膜的至少一部分渗透物作为洗涤液。

9. 发明申请

US20130011865A1 MARKER FOR DETECTING GASTRIC CANCER AND METHOD FOR DETECTING GASTRIC CANCER 审中-公开
标题翻译：用于检测胃癌的标记物和用于检测胃癌的方法
公开(公告)号：US20130011865A1
公开(公告)日：2013-01-10
申请号：US13582382
申请日：2011-03-03
申请人： Michimoto Kobayashi , Yoshinori Tanaka , Satoko Kanamori , Giman Jung , Yoshiharu Sakai , Hiroshi Okabe
发明人： Michimoto Kobayashi , Yoshinori Tanaka , Satoko Kanamori , Giman Jung , Yoshiharu Sakai , Hiroshi Okabe
IPC分类号： G01N33/574 , G01N21/64 , C07K16/18
CPC分类号： G01N33/57446 , C07K14/4702 , G01N33/57488
摘要： It is intended to provide a method for detecting gastric cancer, which is low invasive to a human test subject and has high detection sensitivity and accuracy. The present invention provides a method comprising measuring in vitro the amount of Cofilin 1 protein, a variant thereof, and/or a fragment thereof in a body fluid sample derived from a human test subject, and detecting the presence or absence of gastric cancer affecting the test subject on the basis of the amount, and a kit for gastric cancer diagnosis comprising an antibody capable of specifically binding to the protein.
摘要翻译：目的在于提供一种检测对人体检测对象侵袭性低，检测灵敏度高，准确度高的胃癌的方法。本发明提供了一种方法，其包括在体外测定源自人类受检者的体液样品中的Cofilin1蛋白，其变体和/或其片段的量，并检测是否存在影响基于该量的测试对象，以及包含能够特异性结合蛋白质的抗体的胃癌诊断试剂盒。

10. 发明申请

US20110287444A1 IMMUNOASSAY METHOD FOR HUMAN CXCL1 PROTEIN 有权
标题翻译：人CXCL1蛋白免疫组化方法
公开(公告)号：US20110287444A1
公开(公告)日：2011-11-24
申请号：US13126877
申请日：2009-10-29
申请人： Satoko Kanamori , Giman Jung , Yoshinori Tanaka , Aiko Takayama
发明人： Satoko Kanamori , Giman Jung , Yoshinori Tanaka , Aiko Takayama
IPC分类号： G01N33/577 , C07K16/24
CPC分类号： C07K16/24 , A61K2039/505 , C07K2317/34 , C07K2317/565 , C07K2317/76 , G01N33/543 , G01N33/6857 , G01N33/6863 , G01N2333/522
摘要： An object of the present invention is to detect a human CXCL1 protein with high sensitivity. An immunoassay method is provided for a human CXCL1 protein, by which human CXCL1 or a fragment thereof in a sample is measured using two or more types of anti-human CXCL1 monoclonal antibodies or fragments thereof, wherein: each of the two or more types of anti-human CXCL1 monoclonal antibodies or fragments thereof specifically recognizes any one of sequence regions of the amino acid sequences shown in SEQ ID NOS: 1-3, which are partial sequences of the amino acid sequence composing a human CXCL1 protein; and the two or more types of anti-human CXCL1 monoclonal antibodies or fragments thereof specifically recognize sequence regions that differ from each other. Monoclonal antibodies or fragments thereof are provided, each of which specifically recognizes any one sequence region of the amino acid sequences shown in SEQ ID NOS: 1-3 and has a new amino acid sequence.
摘要翻译：本发明的目的是高灵敏度地检测人CXCL1蛋白。提供了人CXCL1蛋白的免疫测定方法，通过该方法，使用两种或更多种抗人CXCL1单克隆抗体或其片段测量样品中的人CXCL1或其片段，其中：所述两种或更多种类型的抗人CXCL1单克隆抗体或其片段特异性识别作为构成人CXCL1蛋白的氨基酸序列的部分序列的SEQ ID NO：1-3所示的氨基酸序列的任何一个序列区域; 两种以上抗人CXCL1单克隆抗体或其片段特异性识别彼此不同的序列区。提供了单克隆抗体或其片段，其各自特异性识别SEQ ID NO：1-3所示的氨基酸序列的任何一个序列区，并具有新的氨基酸序列。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式