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1. 发明授权

US11673136B2 Nanopore devices for sensing biomolecules 有权
公开(公告)号：US11673136B2
公开(公告)日：2023-06-13
申请号：US15945717
申请日：2018-04-04
申请人： Quan Qing , Yuan Wang , Joshua Sadar
发明人： Quan Qing , Yuan Wang , Joshua Sadar
IPC分类号： B01L3/00 , C12Q1/6869 , G01N27/327 , B82Y15/00 , G01N33/487
CPC分类号： B01L3/5027 , B01L3/502707 , B01L3/502761 , C12Q1/6869 , G01N27/3276 , G01N27/3278 , B01L2300/0645 , B01L2300/0896 , B82Y15/00 , G01N33/48721 , C12Q1/6869 , C12Q2565/607 , C12Q2565/629 , C12Q2565/631
摘要： The present disclosure provides chips, devices and methods for sequencing a biomolecule. The biomolecule may be DNA, RNA. a protein, or a peptide. The chip comprises a substrate; a first and second fluid chamber; fluid channels connecting the first and second fluid chamber; a first and second electrode disposed on opposing sides of the central fluid channel and having a nanogap therebetween, wherein the width of the nanogap is modulated by confined electrochemical deposition; and a passivation layer disposed on top of the first and second electrodes and the fluid channel.

2. 发明公开

US20230247910A1 METHOD FOR CONSTRUCTING MAGNETIC TUNNELING JUNCTION DEVICES AND USE OF DEVICE FOR SPIN-DEPENDENT TRANSPORT CHARACTERIZATION 审中-公开
公开(公告)号：US20230247910A1
公开(公告)日：2023-08-03
申请号：US18004660
申请日：2021-07-06
申请人： Quan Qing
发明人： Quan Qing
IPC分类号： H10N50/01 , H10N50/10 , H10N50/20
CPC分类号： H10N50/01 , H10N50/10 , H10N50/20
摘要： A magnetic tunneling junction (MTJ) device structure and the method of constructing such device are disclosed. Also disclosed are methods of using the device for spin-dependent transport characterization through biomolecules for structure and dynamic function analysis in physiological environments.

3. 发明授权

US09297796B2 Bent nanowires and related probing of species 有权
标题翻译：弯曲纳米线和相关物种探测
公开(公告)号：US09297796B2
公开(公告)日：2016-03-29
申请号：US13497852
申请日：2010-09-24
申请人： Bozhi Tian , Ping Xie , Thomas J. Kempa , Charles M. Lieber , Itzhaq Cohen-Karni , Quan Qing , Xiaojie Duan
发明人： Bozhi Tian , Ping Xie , Thomas J. Kempa , Charles M. Lieber , Itzhaq Cohen-Karni , Quan Qing , Xiaojie Duan
IPC分类号： B82Y99/00 , H01L29/06 , H01L21/20 , G01N33/487 , B82Y10/00 , B82Y15/00 , H01L29/04
CPC分类号： G01N27/4146 , B82Y10/00 , B82Y15/00 , G01N33/48728 , H01L21/02603 , H01L29/045 , H01L29/0665 , H01L29/0669 , H01L51/0048
摘要： Kinked nanowires are used for measuring electrical potentials inside simple cells. An improved intracellular entrance is achieved by modifying the kinked nanowires with phospholipids.
摘要翻译：扭曲的纳米线用于测量简单电池内的电位。改进的细胞内入口通过用磷脂修饰扭结的纳米线来实现。

4. 发明申请

US20120267604A1 BENT NANOWIRES AND RELATED PROBING OF SPECIES 有权
标题翻译： BENT NANOWIRES和相关物种的探索
公开(公告)号：US20120267604A1
公开(公告)日：2012-10-25
申请号：US13497852
申请日：2010-09-24
申请人： Bozhi Tian , Ping Xie , Thomas J. Kempa , Charles M. Lieber , Itzhaq Cohen-Karni , Quan Qing , Xiaojie Duan
发明人： Bozhi Tian , Ping Xie , Thomas J. Kempa , Charles M. Lieber , Itzhaq Cohen-Karni , Quan Qing , Xiaojie Duan
IPC分类号： H01L29/06 , H01L21/20 , B82Y99/00
CPC分类号： G01N27/4146 , B82Y10/00 , B82Y15/00 , G01N33/48728 , H01L21/02603 , H01L29/045 , H01L29/0665 , H01L29/0669 , H01L51/0048
摘要： Kinked nanowires are used for measuring electrical potentials inside simple cells. An improved intracellular entrance is achieved by modifying the kinked nanowires with phospholipids.
摘要翻译：扭曲的纳米线用于测量简单电池内的电位。改进的细胞内入口通过用磷脂修饰扭结的纳米线来实现。

5. 发明申请

US20070236968A1 POWER SUPPLY WITH RIPPLE ATTENUATOR 审中-公开
标题翻译：电源电源带纹波衰减器
公开(公告)号：US20070236968A1
公开(公告)日：2007-10-11
申请号：US11554340
申请日：2006-10-30
申请人： Quan-Qing Wu , Hong-Jian Gan
发明人： Quan-Qing Wu , Hong-Jian Gan
IPC分类号： H02M1/12
CPC分类号： H02M1/4225 , H02M1/14 , Y02B70/126 , Y02P80/112
摘要： A power supply configured for converting an input AC voltage into an output DC voltage having a desired voltage level is provided. The power supply includes a front-end power converter such as a PFC converter which is configured to convert the input AC voltage into an intermediate DC voltage generated across an output capacitive unit, and a back-end power converter such as a DC-DC converter which is configured to convert the intermediate DC voltage into an output DC voltage having a desired voltage level. The power supply further includes a resonant network consisted of a filter which is made up of at least one inductive filtering element having an inductive impedance and a capacitive filtering element having a capacitive impedance. The resonant network is placed between the front-end power converter and the back-end power converter, and coupled with the output capacitive unit for filtering the current flowing into the output capacitive unit.
摘要翻译：提供了一种被配置为将输入AC电压转换为具有期望电压电平的输出DC电压的电源。电源包括前置功率转换器，诸如PFC转换器，其被配置为将输入的AC电压转换成跨越输出电容单元生成的中间DC电压;以及后端功率转换器，诸如DC-DC转换器其被配置为将中间DC电压转换成具有期望电压电平的输出DC电压。电源还包括由至少一个具有电感阻抗的感应滤波元件和具有电容性阻抗的电容滤波元件组成的滤波器组成的谐振网络。谐振网络放置在前端功率转换器和后端功率转换器之间，并与输出电容单元耦合，用于滤除流入输出电容单元的电流。

6. 发明申请

US20180280968A1 NANOPORE DEVICES FOR SENSING BIOMOLECULES 审中-公开
公开(公告)号：US20180280968A1
公开(公告)日：2018-10-04
申请号：US15945717
申请日：2018-04-04
申请人： Quan Qing , Yuan Wang , Joshua Sadar
发明人： Quan Qing , Yuan Wang , Joshua Sadar
IPC分类号： B01L3/00 , C12Q1/6869 , G01N27/327
摘要： The present disclosure provides chips, devices and methods for sequencing a biomolecule. The biomolecule may be DNA, RNA. a protein, or a peptide. The chip comprises a substrate; a first and second fluid chamber; fluid channels connecting the first and second fluid chamber; a first and second electrode disposed on opposing sides of the central fluid channel and having a nanogap therebetween, wherein the width of the nanogap is modulated by confined electrochemical deposition; and a passivation layer disposed on top of the first and second electrodes and the fluid channel.

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