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1. 发明授权

US5639277A Embolic coils with offset helical and twisted helical shapes 失效
标题翻译：具有偏移螺旋和扭曲螺旋形状的栓塞线圈
公开(公告)号：US5639277A
公开(公告)日：1997-06-17
申请号：US538557
申请日：1995-09-29
申请人： Michael J. Mariant , Gregory E. Mirigian , Nga T. Van , Roberto L. Orellana , Christopher G. M. Ken
发明人： Michael J. Mariant , Gregory E. Mirigian , Nga T. Van , Roberto L. Orellana , Christopher G. M. Ken
IPC分类号： A61M25/00 , A61B17/12 , A61F2/82 , A61L27/00 , F16F1/04 , A61M29/00
CPC分类号： A61B17/1215 , A61B17/12022 , A61B17/12109 , A61B17/12145 , F16F1/04
摘要： This is a surgical device that, in particular, is for forming a vasoocclusion or embolism. Typically, it is a helically wound coil in which the helix is wound in such a way as to have multiple axially offset, longitudinal or focal axes. Another important facet of the invention is the presence of small diameter secondary coil windings adjacent large diameter coil windings. The device is sufficiently flexible and small that it may be delivered to a site within the vasculature of the human body using a pusher and a catheter. The device is generally linear when within the catheter but relaxes to form the multi-focal form after delivery from the distal end of the catheter lumen. Various mechanical connections may also be used to discharge the inventive coil from its pusher. Similarly, the coil may be attached to a pusher using a sacrificial joint, which sacrificial joint is dissolved by imposition of a small voltage within the human body. The device may be used alone or in conjunction with other coils or with a fibrous thrombotic attachments or the substrate to localize subsequent infusion of tissue adhesives, other particulate embolization devices, or chemotherapeutic agents in abnormal blood vessels and tissues.
摘要翻译：这是一种手术装置，特别是用于形成血栓栓塞或栓塞。通常，它是螺旋缠绕的线圈，其中螺旋线被卷绕成具有多个轴向偏移的纵向或焦点轴线。本发明的另一个重要方面是存在与大直径线圈绕组相邻的小直径次级线圈绕组。该装置具有足够的柔性和小度，使得其可以使用推动器和导管将其输送到人体脉管系统内的部位。该装置在导管内通常是线性的，但是在从导管腔的远端递送之后松弛以形成多焦点形式。也可以使用各种机械连接来从其推动器排出本发明的线圈。类似地，线圈可以使用牺牲接头附接到推动器，该牺牲接头通过在人体内施加小的电压而被溶解。该装置可以单独使用或与其它线圈一起使用，或与纤维性血栓形成附着物或基质一起使用，以便将异常血管和组织中的组织粘合剂，其它颗粒栓塞装置或化学治疗剂的随后输注定位。

2. 发明授权

US5382259A Vasoocclusion coil with attached tubular woven or braided fibrous covering 失效
标题翻译：血管闭塞线圈附有管状编织或编织纤维覆盖物
公开(公告)号：US5382259A
公开(公告)日：1995-01-17
申请号：US965973
申请日：1992-10-26
申请人： James J. Phelps , Nga T. Van
发明人： James J. Phelps , Nga T. Van
IPC分类号： A61B17/12 , A61F2/01 , D04C1/06 , A61F2/02 , A61B17/00
CPC分类号： D04C1/06 , A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0006 , A61F2230/0069 , A61F2230/0076 , A61F2230/0091
摘要： This invention is in the field of vasoocclusion devices. More particularly, it relates to a vasoocclusion coil which may be segmented, onto which a fibrous, woven or braided, tubular covering or element is attached.
摘要翻译：本发明在血管闭塞装置领域。更具体地说，本发明涉及一种可被分段的血管闭塞线圈，纤维，织造或编织的管状覆盖物或元件附接到该线圈上。

3. 发明授权

US5549624A Fibered vasooclusion coils 失效
标题翻译：纤维血管闭塞线圈
公开(公告)号：US5549624A
公开(公告)日：1996-08-27
申请号：US265188
申请日：1994-06-24
申请人： Gregory E. Mirigian , Nga T. Van
发明人： Gregory E. Mirigian , Nga T. Van
IPC分类号： A61B17/00 , A61B17/12 , A61B19/00
CPC分类号： A61B17/12145 , A61B17/12022 , A61B17/1215
摘要： This invention is a vasoocclusive device. It is placed in the vasculature of an animal to form thrombus in a selected site such as an aneurysm or AVM. The device uses a central coil having thrombogenic fibers placed on the coil in a specified fashion. The coil will pass through the lumen of a vascular catheter and form a convolution when ejected from the catheter's distal end. The fibers are attached to the coil and cooperate with the coil so that upon ejection from the catheter, the convoluted coil forms a shape in which the central region contains the majority of these fibers.
摘要翻译：本发明是血管闭塞装置。将其置于动物的脉管系统中，以在选定的部位如动脉瘤或AVM中形成血栓。该装置使用具有以特定方式放置在线圈上的血栓形成纤维的中心线圈。线圈将穿过血管导管的内腔，并在从导管的远端喷射时形成卷积。纤维连接到线圈并与线圈配合，使得当从导管喷射时，卷积的线圈形成中心区域包含大多数这些纤维的形状。

4. 发明授权

US06254592B1 Variable stiffness coils 失效
标题翻译：可变刚度线圈
公开(公告)号：US06254592B1
公开(公告)日：2001-07-03
申请号：US09073116
申请日：1998-05-05
申请人： Gene Samson , Ivan Sepetka , U. Hiram Chee , Christopher G.M. Ken , Nga T. Van
发明人： Gene Samson , Ivan Sepetka , U. Hiram Chee , Christopher G.M. Ken , Nga T. Van
IPC分类号： A61B1700
CPC分类号： A61B17/1215 , A61B17/12022 , A61B17/12109 , A61B17/12145
摘要： An implantable vaso-occlusive device, constructed of a helically wound coil having a central section along its longitudinal axis which is somewhat stiffer than at least one of its end regions.
摘要翻译：一种可植入血管闭塞装置，其由螺旋缠绕的线圈构成，该线圈具有沿着其纵向轴线的中心部分，该中心部分比其端部区域中的至少一个稍微更硬。

5. 发明授权

US5522822A Vasoocclusion coil with attached tubular woven or braided fibrous covering 失效
公开(公告)号：US5522822A
公开(公告)日：1996-06-04
申请号：US323951
申请日：1994-10-17
申请人： James J. Phelps , Nga T. Van
发明人： James J. Phelps , Nga T. Van
IPC分类号： A61B17/12 , A61F2/01 , D04C1/06 , A61B17/00
CPC分类号： D04C1/06 , A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0006 , A61F2230/0069 , A61F2230/0076 , A61F2230/0091
摘要： This invention is in the field of vasoocclusion devices. More particularly, it relates to a vasoocclusion coil which may be segmented, onto which a fibrous, woven or braided, tubular covering or element is attached.

6. 发明授权

US5766160A Variable stiffness coils 失效
标题翻译：可变刚度线圈
公开(公告)号：US5766160A
公开(公告)日：1998-06-16
申请号：US480042
申请日：1995-06-06
申请人： Gene Samson , Ivan Sepetka , U. Hiram Chee , Christopher G. M. Ken , Nga T. Van
发明人： Gene Samson , Ivan Sepetka , U. Hiram Chee , Christopher G. M. Ken , Nga T. Van
IPC分类号： A61M31/00 , A61B17/12 , A61B17/00
CPC分类号： A61B17/1215 , A61B17/12022 , A61B17/12109 , A61B17/12145
摘要： This invention is an implantable vaso-occlusive device. It is a helically wound coil having a central section along its longitudinal axis which is somewhat stiffer than at least one of its end regions.
摘要翻译：本发明是可植入血管闭塞装置。它是螺旋缠绕的线圈，其沿其纵向轴线具有中心部分，该中心部分比其端部区域中的至少一个稍微更硬。

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