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1. 发明授权

US10711214B2 Production of a carbonaceous feedstock material from a waste carbon source 有权
公开(公告)号：US10711214B2
公开(公告)日：2020-07-14
申请号：US15568135
申请日：2016-02-08
申请人： NORTH-WEST UNIVERSITY
发明人： Frans Boudewijn Waanders , Sanette Marx , John Reginald Bunt
IPC分类号： C10L10/02 , C10L5/04 , C10L5/36 , C10L9/08 , C10L9/10 , C10L5/02 , C10L5/44
摘要： The production carbonaceous feedstock material from waste containing carbon sources and the use thereof in gasification processes for hazardous emissions of greenhouse gases and sulphur are significantly minimized and enhanced reaction rates are described. A process for producing a carbonaceous feedstock material from waste containing carbon sources, including the steps consisting of: (i) introducing a source of biochar to a source of discard coal fines to form a bio-coal mixture; (ii) introducing a catalyst additive selected from the group consisting of a source of an alkali metal or a source of an alkaline earth metal to the bio-coal mixture; (iii) optionally, contacting the bio-coal mixture with a binder; and (iv) compacting the resulting mixture of step (ii) or (iii) to form one or more carbonaceous feedstock briquettes, the size of said briquettes having a dimension of at least 5 mm.

2. 发明授权

US10363324B2 Pharmaceutical composition 有权
公开(公告)号：US10363324B2
公开(公告)日：2019-07-30
申请号：US15034281
申请日：2014-11-04
申请人： The South African Nuclear Energy Corporation Limited , North-West University
发明人： Anne Frederica Grobler , Jan Rijn Zeevaart
IPC分类号： A61K51/12 , A61K9/00 , A61K47/02 , A61K47/12 , A61K47/14 , A61K9/107
摘要： This invention relates to a pharmaceutical composition for parenteral or oral administration containing a radioactive compound which can be used diagnostically or therapeutically. The composition comprises a micro-emulsion constituted by a dispersion of vesicles or microsponges of a fatty acid based component in an aqueous or other pharmacologically acceptable carrier in which nitrous oxide is dissolved, the fatty acid based component comprising at least one long chain fatty acid based substance selected from the group consisting of free fatty acids and derivatives of free fatty acids, and the radioactive compound.

3. 发明授权

US10321681B2 Plant support formulation, vehicle for the delivery and translocation of phytologically beneficial substances and compositions containing same 有权
公开(公告)号：US10321681B2
公开(公告)日：2019-06-18
申请号：US14206251
申请日：2014-03-12
申请人： NORTH-WEST UNIVERSITY
发明人： Anne Frederica Grobler
IPC分类号： A01N37/02 , A01N43/653 , A01N25/04 , A01N37/06
摘要： A plant supporting formulation which is also suitable for use as a delivery vehicle, or a component of a delivery vehicle, for the delivery of one or more phytologically beneficial substances to a plant, and for enhancing the translocation of such delivered substance(s) in or on the plant, the formulation comprising a micro-emulsion constituted by a dispersion of vesicles or microsponges of a fatty acid based component in an aqueous carrier, the fatty acid based component comprising at least one long chain fatty acid based substance selected from the group consisting of free fatty acids and derivatives of free fatty acids. The dispersion is preferably characterized in that at least 50% of the vesicles or microsponges are of a diametrical size of between 50 nm and 5 micrometer. The dispersion is further also characterized in that the micro-emulsion has a zeta potential of between −25 mV and −60 mV.

4. 发明申请

US20180119040A1 PRODUCTION OF A CARBONACEOUS FEEDSTOCK MATERIAL FROM A WASTE CARBON SOURCE 审中-公开
公开(公告)号：US20180119040A1
公开(公告)日：2018-05-03
申请号：US15568135
申请日：2016-02-08
申请人： NORTH-WEST UNIVERSITY
发明人： Frans Boudewijn WAANDERS , Sanette MARX , John Reginald BUNT
IPC分类号： C10L10/02 , C10L5/36 , C10L9/08 , C10L9/10
摘要： The production carbonaceous feedstock material from waste containing carbon sources and the use thereof in gasification processes for hazardous emissions of greenhouse gases and sulphur are significantly minimized and enhanced reaction rates are described. A process for producing a carbonaceous feedstock material from waste containing carbon sources, including the steps consisting of: (i) introducing a source of biochar to a source of discard coal fines to form a bio-coal mixture; (ii) introducing a catalyst additive selected from the group consisting of a source of an alkali metal or a source of an alkaline earth metal to the bio-coal mixture; (iii) optionally, contacting the bio-coal mixture with a binder; and (iv) compacting the resulting mixture of step (ii) or (iii) to form one or more carbonaceous feedstock briquettes, the size of said briquettes having a dimension of at least 5 mm.

5. 发明申请

US20170073650A1 RECOMBINANT THERAPEUTIC GLYCINE N-ACYLTRANSFERASE 审中-公开
标题翻译：重组治疗糖蛋白N-酰基转移酶
公开(公告)号：US20170073650A1
公开(公告)日：2017-03-16
申请号：US15274234
申请日：2016-09-23
申请人： North-West University
发明人： Lodewyk Jacobus Mienie , Alberdina Aike Van Dijk , Christoffel Petrus Stephanus Badenhorst , Rencia Van Der Sluis
IPC分类号： C12N9/10 , C12P21/02
CPC分类号： C12N9/1029 , C12P21/02 , C12Y203/01013
摘要： This invention relates to a method of producing a recombinant enzyme, more particularly, this invention relates to a method of producing water soluble enzymatically active recombinant glycine N-acyltransferase (GLYAT (E.G. 2.1.3.13)), including the steps of providing a suitable expression host; preparing a vector including a gene for expressing GLYAT in the expression host to form an expression plasmid; transforming the host with the expression plasmid to form an expression system; expressing the GLYAT gene in the expression system; and separating the expressed GLYAT from the expression system.
摘要翻译：本发明涉及一种生产重组酶的方法，更具体地说，本发明涉及一种生产水溶性酶活性重组甘氨酸N-酰基转移酶（GLYAT（EG2.1.3.13））的方法，包括提供合适表达的步骤主办; 制备包含用于在表达宿主中表达GLYAT的基因以形成表达质粒的载体; 用表达质粒转化宿主以形成表达系统; 在表达系统中表达GLYAT基因; 并将表达的GLYAT与表达系统分离。

6. 发明申请

US20130336990A1 ENHANCEMENT OF THE ACTION OF ANTI-INFECTIVE AGENTS AND OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM AGENTS AND TRANSPORTATION OF NUCLEIC ACID SUBSTANCES 审中-公开
标题翻译：增强抗感染药物和中枢和外周神经系统药物和运输核酸物质的作用
公开(公告)号：US20130336990A1
公开(公告)日：2013-12-19
申请号：US13709596
申请日：2012-12-10
申请人： North West University
发明人： Petrus Johannes MEYER
IPC分类号： A61K31/7088 , A61K38/02 , C12N15/63 , A61K39/395
CPC分类号： A61K31/7088 , A61K9/0019 , A61K9/4866 , A61K31/133 , A61K31/4409 , A61K31/496 , A61K31/4965 , A61K38/02 , A61K39/39533 , A61K47/02 , C12N15/63
摘要： The invention provides a method of enhancing the action of a pharmaceutical agent selected from the group consisting of the anti-infective agents, the group comprising of the antimicrobial agents, the anthelmintic agents and the anti-ectoparasitic agents, but excluding coal tar solution and H1-antagonist antihistamines, and from the group consisting of the CPNS agents selected from the group of compounds acting on the central or peripheral nervous system, but excluding coal tar solution and H1-antagonist antihistamines and also excluding anti-inflammatory, analgesic and antipyretic agents and also provides an enhanced method for the administration of a nucleic acid substance to the cells of an animal, a plant or a micro-organism. The method is characterised in that the agent or nucleic acid substance is formulated with an administration medium which comprises a solution of nitrous oxide gas in a pharmaceutically acceptable carrier solvent for the gas and which administration medium includes at least one fatty acid or ester or other suitable derivative thereof selected from the group consisting of oleic acid, linoleic acid, alpha-linolenic acid, gamma-linolenic acid, arachidonic acid, eicosapentaenoic acid [C20:5ω3], decosahexaenoic acid [C22:6ω3], ricinoleic acid and derivatives thereof selected from the group consisting of the C1 to C6 alkyl esters thereof, the glycerol-polyethylene glycol esters thereof and the reaction product of hydrogenated natural oils composed largely of ricinoleic acid based oils, such as castor oil with ethylene oxide. The formulations of such agents or substances form part of the invention
摘要翻译：本发明提供一种增强选自抗感染剂，抗微生物剂组，驱肠虫剂和抗外寄生剂组，但不包括煤焦油溶液和H1的药剂的作用的方法 - 拮抗剂抗组胺剂，以及选自选自作用于中枢或周围神经系统的化合物组，但不包括煤焦油溶液和H1-拮抗剂抗组胺剂的CPNS药剂组，并且除了消炎止痛和解热剂之外还提供了用于向动物，植物或微生物的细胞施用核酸物质的增强的方法。该方法的特征在于，所述试剂或核酸物质与给药培养基一起配制，所述施用培养基包含一氧化二氮气体在用于气体的药学上可接受的载体溶剂中的溶液，并且所述施用培养基包括至少一种脂肪酸或酯或其它合适的衍生物，其选自油酸，亚油酸，α-亚麻酸，γ-亚麻酸，花生四烯酸，二十碳五烯酸[C20：5omega3]，十二碳六烯酸[C22：6omega3]，蓖麻油酸及其衍生物由其C1至C6烷基酯，其甘油 - 聚乙二醇酯和主要由蓖麻油酸基油（例如蓖麻油与环氧乙烷）组成的氢化天然油的反应产物组成的组。这些试剂或物质的制剂形成本发明的一部分

7. 发明申请

US20180296196A1 METHOD AND DEVICE FOR COLLECTING MYCOBACTERIUM COMPLEX SPECIES FROM TEH ORAL CAVITY OF A PATIENT 审中-公开
公开(公告)号：US20180296196A1
公开(公告)日：2018-10-18
申请号：US15578842
申请日：2016-06-01
申请人： NORTH-WEST UNIVERSITY , STELLENBOSCH UNIVERSITY , UNIVERSITY OF NEBRASKA-LINCOLN
发明人： Anne Frederica GROBLER , Lizl CRONJE , Hendrik VILJOEN
IPC分类号： A61B10/00 , A61J17/00 , G01N33/569
摘要： This invention relates to a method and device for collecting a Mycobacterium complex species, such Mycobacterium tuberculosis (MTB) from the oral cavities of particularly children and infants. A device is provided which has a distal end and an operative end portion manufactured from a parent polymer which has been functionalised with a chemical compound having an affinity to the Mycobacterium complex species to collect same such that the presence thereof in the sample can be detected. The invention further extends to a method of preparing biological material obtained from such collected sample.

8. 发明授权

US09831789B2 Switched mode drive circuit 有权
公开(公告)号：US09831789B2
公开(公告)日：2017-11-28
申请号：US14769960
申请日：2013-02-25
申请人： NORTH-WEST UNIVERSITY
发明人： Barend Visser , Petrus Paulus Krüger
IPC分类号： H02M3/337 , H01F27/38 , H02M3/338
CPC分类号： H02M3/337 , H01F27/38 , H02M3/338
摘要： A switched mode drive circuit 10 comprises a first switch 14 having a first terminal 14.1 and a second terminal 14.2, a second switch 16 having a first terminal 16.1 and a second terminal 16.2, an inductive component 20 comprising at least a first winding part 20.1 having a first end 20.1.1 and a second end 20.1.2 and a second winding part 20.2 having a first end 20.2.1 and a second end 20.2.2 and an energy storage device 18 having a first pole 18.1 and a second pole 18.2. The first and second terminals of each of the first and second switches and the first and second ends of each of the first and second winding parts are connected in series over the first and second poles of the energy storage device and the first and second winding parts are configured in one of a common mode and a differential mode.

9. 发明申请

US20170324222A1 IGNITION PLUG 有权
公开(公告)号：US20170324222A1
公开(公告)日：2017-11-09
申请号：US15522267
申请日：2015-10-28
申请人： NORTH-WEST UNIVERSITY
发明人： Petrus Paulus KRÜGER , Barend VISSER
IPC分类号： H01T13/20 , H01T13/50 , H01T13/52 , H01T19/00
CPC分类号： H01T13/20 , H01T13/50 , H01T13/52 , H01T19/00 , H01T21/02
摘要： An ignition plug 10 comprises an elongate cylindrical body 12 of an electrically insulating material having a first end 12.1, a second end 12.2 opposite to the first end and a first face 14 at the first end. A first elongate electrode 16 having a first end 16.1 and a second end 16.2 extends longitudinally in the body. The first electrode terminates at the first end thereof a first distance d1 from the first end of the body in a direction towards the second end of the body. The body hence defines a blind bore 18 extending between the first end of the first electrode and the first end of the body. A second electrode is provided on an outer surface of the body and terminates at one of a) flush with the first face 14 of the body and b) a second distance d2 from the first end of the body in a direction towards the second end of the bod.

10. 发明申请

US20140194288A1 PLANT SUPPORT FORMULATION, VEHICLE FOR THE DELIVERY AND TRANSLOCATION OF PHYTOLOGICALLY BENEFICIAL SUBSTANCES AND COMPOSITIONS CONTAINING SAME 审中-公开
标题翻译：植物支持制剂，用于交付和转移生物学上有益物质的物质和包含其的组合物
公开(公告)号：US20140194288A1
公开(公告)日：2014-07-10
申请号：US14206251
申请日：2014-03-12
申请人： North-West University
发明人： Anne Frederica GROBLER
IPC分类号： A01N37/06 , A01N43/653
CPC分类号： A01N43/653 , A01N25/04 , A01N37/02 , A01N37/06 , A01N2300/00
摘要： A plant supporting formulation which is also suitable for use as a delivery vehicle, or a component of a delivery vehicle, for the delivery of one or more phytologically beneficial substances to a plant, and for enhancing the translocation of such delivered substance(s) in or on the plant, the formulation comprising a micro-emulsion constituted by a dispersion of vesicles or microsponges of a fatty acid based component in an aqueous carrier, the fatty acid based component comprising at least one long chain fatty acid based substance selected from the group consisting of free fatty acids and derivatives of free fatty acids. The dispersion is preferably characterized in that at least 50% of the vesicles or microsponges are of a diametrical size of between 50 nm and 5 micrometer. The dispersion is further also characterized in that the micro-emulsion has a zeta potential of between −25 mV and −60 mV.
摘要翻译：一种植物支持制剂，其也适用于作为递送载体或递送载体的组分，用于将一种或多种植物有益物质递送至植物，以及用于增强这些递送物质的易位或在植物上，所述制剂包含由水性载体中脂肪酸组分的囊泡或微球分散体构成的微乳液，所述脂肪酸基组分包含至少一种长链脂肪酸基物质，所述物质选自由游离脂肪酸和游离脂肪酸的衍生物组成。该分散体的特征在于，至少50％的囊泡或微球的直径尺寸为50nm至5微米。该分散体的特征还在于微乳液的ζ电位在-25mV和-60mV之间。

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