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1. 发明授权

US10307244B2 Methods and apparatus for treatment of aneurysms adjacent branch arteries 有权
公开(公告)号：US10307244B2
公开(公告)日：2019-06-04
申请号：US13091363
申请日：2011-04-21
申请人： Prema Ganesan , Jonathan Morris , David R. Erickson , Matthew Rust , Curtis Hanson , Jack Chu , Charles Thomas
发明人： Prema Ganesan , Jonathan Morris , David R. Erickson , Matthew Rust , Curtis Hanson , Jack Chu , Charles Thomas
IPC分类号： A61F2/07 , A61F2/06 , A61F2/89 , A61F2/90
摘要： A polymer coating/ring is employed to aid in the sealing and connection of modular elements used in body flow lumens for the exclusion and bypass of diseased regions of the flow lumen, such as where aneurysm occurs adjacent to branching blood vessels.

2. 发明授权

US10300207B2 Multiple dosage injector with rotating screw dosage system 有权
公开(公告)号：US10300207B2
公开(公告)日：2019-05-28
申请号：US14771300
申请日：2014-03-12
申请人： Benjamin Newton , Patrick Madsen , Matthew Rust , Janice Cox
发明人： Benjamin Newton , Patrick Madsen , Matthew Rust , Janice Cox
IPC分类号： A61M5/20 , A61M5/24 , A61M5/315 , G01F11/02
摘要： A dispensing mechanism for delivering a dosage of medicament including a housing having a proximal-distal axis; a plunger rod having a screw thread and configured to advance along the proximal-distal axis relative to the housing; a user-operable push button moveable along the proximal-distal axis relative to the housing; a twist driver threadably engaged with the push button such that movement of the push button towards the distal end of the housing causes rotation of the twist driver about the proximal-distal axis; and a driver engaged with the twist driver such that rotation of the twist driver causes rotation of the driver, the driver also engaged with a portion of the plunger rod such that rotation of the driver causes rotation of the plunger rod, advancing the plunger rod along the proximal-distal axis relative to the housing.

3. 发明授权

US09561102B2 Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve 有权
标题翻译：经导管输送系统和方法与受控的心脏瓣膜扩张和收缩
公开(公告)号：US09561102B2
公开(公告)日：2017-02-07
申请号：US13149160
申请日：2011-05-31
申请人： Matthew Rust , Savage Padraig , Gianfranco Pellegrini , Finn Rinne
发明人： Matthew Rust , Savage Padraig , Gianfranco Pellegrini , Finn Rinne
IPC分类号： A61F2/24 , A61F2/95 , A61F2/966
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2427 , A61F2/2439 , A61F2002/9505 , A61F2002/9665 , A61F2230/005 , A61F2230/0054 , A61F2230/008
摘要： A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.
摘要翻译：一种与具有附接有阀结构的支架框架的假体心脏瓣膜一起使用的输送系统，包括轴组件，所述轴组件包括远端和设置在远端附近的联接结构，并且构造成联接到远端假心脏瓣膜该系统包括限定尺寸适于可滑动地容纳轴组件的内腔的护套组件。输送系统被配置成从其中护套组件包围假体心脏瓣膜的负载状态转变到其中护套组件从假体心脏瓣膜抽出的展开状态。联接结构构造成基于轴组件的远端的纵向运动来提供假体心脏瓣膜的远端的受控的扩张或收缩。

4. 发明申请

US20110301702A1 Transcatheter Delivery System and Method with Controlled Expansion and Contraction of Prosthetic Heart Valve 有权
标题翻译：经导管输送系统和方法，控制扩张和收缩假心脏瓣膜
公开(公告)号：US20110301702A1
公开(公告)日：2011-12-08
申请号：US13149160
申请日：2011-05-31
申请人： Matthew Rust , Savage Padraig , Gianfranco Pellegrini , Finn Rinne
发明人： Matthew Rust , Savage Padraig , Gianfranco Pellegrini , Finn Rinne
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2427 , A61F2/2439 , A61F2002/9505 , A61F2002/9665 , A61F2230/005 , A61F2230/0054 , A61F2230/008
摘要： A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.
摘要翻译：一种与具有附接有阀结构的支架框架的假体心脏瓣膜一起使用的输送系统，包括轴组件，所述轴组件包括远端和设置在远端附近的联接结构，并且构造成联接到远端假心脏瓣膜该系统包括限定尺寸适于可滑动地容纳轴组件的内腔的护套组件。输送系统被配置成从其中护套组件包围假体心脏瓣膜的负载状态转变到其中护套组件从假体心脏瓣膜抽出的展开状态。联接结构构造成基于轴组件的远端的纵向运动来提供假体心脏瓣膜的远端的受控的扩张或收缩。

5. 发明授权

US07815656B2 Method for endovascular bypass stent graft delivery 有权
标题翻译：血管内旁路支架移植物输送方法
公开(公告)号：US07815656B2
公开(公告)日：2010-10-19
申请号：US11464036
申请日：2006-08-11
申请人： Matthew Rust , Prema Ganesan , Curtis Hanson , Jack Chu
发明人： Matthew Rust , Prema Ganesan , Curtis Hanson , Jack Chu
IPC分类号： A61B17/08
CPC分类号： A61F2/07 , A61B17/12022 , A61B17/12109 , A61B17/12118 , A61B17/12131 , A61B17/3403 , A61B2017/00252 , A61F2/06 , A61F2/064 , A61F2/89 , A61F2002/061 , A61F2002/072
摘要： The invention provides a method of providing an endovascular bypass. The method includes the steps of inserting an elastic needle carrying a guidewire adjacent an ostium via a catheter and extending the needle through a branch vessel wall. The method continues by extending the needle through the extravascular space and inserting the needle through a main vessel wall to create an opening. The needle is retracted, leaving the guidewire in place. A bypass stent graft is inserted along the guidewire to provide a pathway between the branch vessel and the main vessel, and the inserted bypass stent graft is expanded. The branch vessel is occluded between the ostium of the bypass stent graft and the main vessel, and a main stent graft is inserted in the main vessel proximate the opening in the main vessel wall.
摘要翻译：本发明提供一种提供血管内旁路的方法。该方法包括以下步骤：通过导管将携带导丝的弹性针插入口附近，并将针延伸穿过分支血管壁。该方法通过将针穿过血管外空间并将针插入主血管壁以创建开口来继续。针缩回，将导丝留在原位。沿着导丝插入旁路支架移植物以提供分支血管和主血管之间的通路，并且插入的旁路支架移植物扩张。分支血管被封闭在旁路支架移植物的口和主血管之间，并且主支架移植物在主血管壁中的开口附近插入主血管。

6. 发明申请

US20100036320A1 MULTIPLE DOSAGE INJECTOR 有权
标题翻译：多剂量注射器
公开(公告)号：US20100036320A1
公开(公告)日：2010-02-11
申请号：US12536106
申请日：2009-08-05
申请人： Janice L. Cox , Matthew Rust , Thomas E. KraMer , Peter Hoeft
发明人： Janice L. Cox , Matthew Rust , Thomas E. KraMer , Peter Hoeft
IPC分类号： A61M5/20
CPC分类号： A61M5/31593 , A61M5/24 , A61M5/3129 , A61M5/31541 , A61M5/31545 , A61M5/31566 , A61M5/3158 , A61M2005/2403 , A61M2005/2407
摘要： A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.
摘要翻译：公开了一种药物分配机构，其配置成从药物室喷射连续剂量的药物。分配机构的一个实施例包括壳体和构造成从腔室喷出剂量的药剂的柱塞杆。分配机构还包括致动机构，其包括与壳体相关联的触发器，并且具有相对于其的就绪和被击发位置。触发器构造成用于由用户操作以便从准备位置到触发位置的大致轴向的计量运动中连续运动，在该位置触发器与柱塞杆相关联，以使柱塞杆弹出预定的一个剂量中的一个体积和从点火位置到包括轴向旋转的就绪位置的复位运动，其中在复位运动期间触发器与柱塞杆脱离。

7. 发明授权

US07615072B2 Endoluminal prosthesis 有权
标题翻译：腔内假体
公开(公告)号：US07615072B2
公开(公告)日：2009-11-10
申请号：US11559723
申请日：2006-11-14
申请人： Matthew Rust , Trevor Greenan , Frank Yang
发明人： Matthew Rust , Trevor Greenan , Frank Yang
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/075 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2220/0016 , A61F2230/0054
摘要： An endoluminal prosthesis including a tubular graft having a proximal end and a distal end; a suprarenal spring stent operably connected to the proximal end, the suprarenal spring stent having suprarenal positive apices and suprarenal negative apices connected in a sinusoidal ring pattern by suprarenal struts; and a sealing spring stent operably connected to the tubular graft, the sealing spring stent having sealing positive apices, sealing negative apices, and intermediate sealing negative apices connected in a ring pattern, the sealing negative apices alternating with the intermediate sealing negative apices between adjacent sealing positive apices, the sealing positive apices being connected to the sealing negative apices by sealing struts, and the sealing positive apices being connected to the intermediate sealing negative apices by intermediate sealing struts. The suprarenal positive apices are axially aligned with the intermediate sealing negative apices.
摘要翻译：包括具有近端和远端的管状移植物的腔内假体; 可操作地连接到近端的超肾上腺弹簧支架，所述肾上段的支架具有通过肾上支柱以正弦环形图案连接的肾上阳性顶点和肾上阴性顶点; 和密封弹簧支架，可操作地连接到管状移植物，密封弹簧支架具有密封正顶点，密封负顶点和以环形图案连接的中间密封负顶点，密封负顶点与相邻密封件之间的中间密封负顶点交替正顶点，密封正顶点通过密封支柱连接到密封负顶点，密封正顶点通过中间密封支柱连接到中间密封负顶点。上肾阳性顶点与中间密封负顶点轴向对准。

8. 发明申请

US20090259295A1 Method of Delivering Graft Material Without the Use of a Stent 审中-公开
标题翻译：在不使用支架的情况下提供移植物质的方法
公开(公告)号：US20090259295A1
公开(公告)日：2009-10-15
申请号：US12102336
申请日：2008-04-14
申请人： Matthew Rust
发明人： Matthew Rust
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61B17/064 , A61B17/068 , A61B17/12022 , A61B17/12118 , A61B2017/1205 , A61F2/06 , A61F2250/0059
摘要： A method of delivering a tubular endoluminal graft through a body lumen in which the graft is expanded and temporarily held in place by an expandable support structure at the distal end of a graft delivery system until staples from an endovascular stapling device can be delivered to permanently secure the graft to the vessel wall. The support structure radially expands to radially expand the graft against a vessel wall. The support structure holds the graft in place while a stapling device is delivered between the outer shaft and the radially expanded graft. The stapling device delivers one or more staples for attaching the graft to the vessel wall. Once the graft is attached to the vessel wall, it is disconnected from the support structure so that the support structure may be radially contracted and the delivery system may be removed.
摘要翻译：一种将管状腔内移植物递送通过体腔的方法，其中移植物通过在移植物递送系统的远端处的可扩张支撑结构膨胀并临时保持在适当的位置，直到来自血管内吻合装置的钉可被递送至永久固定移植到血管壁。支撑结构径向膨胀以使移植物径向扩张抵靠血管壁。支撑结构将移植物保持在适当位置，同时在外轴和径向扩张的移植物之间输送缝合装置。装订装置递送用于将移植物附接到血管壁的一个或多个钉。一旦移植物附接到血管壁上，其与支撑结构断开，使得支撑结构可以径向收缩并且递送系统可以被移除。

9. 发明申请

US20080262595A1 Methods and Apparatus for Treatment of Aneurysms Adjacent to Branch Arteries 有权
标题翻译：用于治疗与分支动脉相邻的动脉瘤的方法和装置
公开(公告)号：US20080262595A1
公开(公告)日：2008-10-23
申请号：US11737432
申请日：2007-04-19
申请人： Jack Chu , David R. Erickson , Jonathan Morris , Prema Ganesan , Curtis Hanson , Matthew Rust , Charles Thomas , James Machek
发明人： Jack Chu , David R. Erickson , Jonathan Morris , Prema Ganesan , Curtis Hanson , Matthew Rust , Charles Thomas , James Machek
IPC分类号： A61F2/06 , A61F2/86 , A61F2/84
CPC分类号： A61F2/962 , A61F2/064 , A61F2/07 , A61F2/89 , A61F2/954 , A61F2002/061 , A61F2002/067 , A61F2002/075 , A61F2002/821 , A61F2002/9511 , A61F2220/005 , A61F2220/0075
摘要： A stent graft includes at least one aperture extending through the main body thereof, into which an extension portion may be deployed for positioning within an adjacent branch flow lumen. The extension portions include self biasing features, wherein the extension is biased into engagement with the main body to seal the interface thereof. Additionally, the extension portion may be configured for tortuous or deviated anatomy, to enable sealing of the extension portion with the body while extending the extension portion in a substantially non-radial direction from the main body.
摘要翻译：支架移植物包括延伸穿过其主体的至少一个孔，延伸部分可以布置在其中以便在相邻的分支流动腔内定位。延伸部分包括自偏压特征，其中延伸部被偏置成与主体接合以密封其接口。另外，延伸部分可以被构造成用于曲折或偏离解剖结构，以使得延伸部分能够与本体密封，同时使延伸部分在基本上非径向方向上从主体延伸。

10. 发明申请

US20060184227A1 Increased friction inner member for stent-graft deployment 审中-公开
标题翻译：增加用于支架移植部署的摩擦内部构件
公开(公告)号：US20060184227A1
公开(公告)日：2006-08-17
申请号：US11056743
申请日：2005-02-11
申请人： Matthew Rust
发明人： Matthew Rust
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/07 , A61F2/89 , A61F2002/075 , A61F2002/9665
摘要： A system for treating a vascular condition and methods for assembling and using such a system. The system includes a catheter inner member, a stent framework, a graft material aligned with the stent framework to form a stent-graft assembly, and a slidable sheath. Multiple bands are spaced along the length of a distal portion of the inner member, each band at least partially encircling the inner member. The stent framework includes multiple rings. The stent-graft assembly is mounted on the inner member such that the stent framework rings are interspaced with the inner member bands. The movable sheath encloses the stent-graft assembly. As the sheath is withdrawn to deploy the stent-graft assembly, the interspaced bands and rings restrict axial movement of the assembly and prevent longitudinal compression or buckling of the assembly, as anchoring of the stent-graft assembly is distributed along the length of the inner member.
摘要翻译：用于治疗血管病症的系统以及用于组装和使用这种系统的方法。该系统包括导管内部构件，支架框架，与支架框架对准以形成支架移植物组件的移植材料以及可滑动护套。多个带沿着内部构件的远端部分的长度间隔开，每个带至少部分地围绕内部构件。支架框架包括多个环。支架移植物组件安装在内部构件上，使得支架框架环与内部构件带间隔开。活动护套包围支架移植物组件。当护套被抽出来部署支架移植物组件时，间隔带和环限制组件的轴向运动并且防止组件的纵向压缩或弯曲，因为支架移植物组件的锚定沿着内侧的长度分布会员。

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