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1. 发明授权

US08440436B2 Production of itaconic acid 有权
标题翻译：衣康酸的生产
公开(公告)号：US08440436B2
公开(公告)日：2013-05-14
申请号：US12669955
申请日：2008-07-21
申请人： Maria Johanna Van Der Werf , Martinus Petrus Maria Caspers , Nicole Van Luijk , Peter Jan Punt
发明人： Maria Johanna Van Der Werf , Martinus Petrus Maria Caspers , Nicole Van Luijk , Peter Jan Punt
IPC分类号： C12P7/46 , C12N9/00 , C12N9/88 , C12N15/00 , C07H21/04
CPC分类号： C12N9/88 , C12P7/46
摘要： The invention relates to the production of itaconic acid in micro-organisms by introducting into a suitable host cell a gene coding for the enzyme cis-aconitic acid decarboxylase, preferably derived from A. terreus. Further part of the invention are host cells, preferably from A. niger, provided with the above mentioned genes.
摘要翻译：本发明涉及通过向合适的宿主细胞中引入编码优选来源于土曲霉的顺式乌头酸脱羧酶的基因而在微生物中生产衣康酸。本发明的另一部分是具有上述基因的宿主细胞，优选来自黑曲霉。

2. 发明申请

US20100311132A1 PRODUCTION OF ITACONIC ACID 有权
标题翻译：生产酸性酸
公开(公告)号：US20100311132A1
公开(公告)日：2010-12-09
申请号：US12669955
申请日：2008-07-21
申请人： Maria Johanna Van Der Werf , Martinus Petrus Maria Caspers , Nicole Van Luijk , Peter Jan Punt
发明人： Maria Johanna Van Der Werf , Martinus Petrus Maria Caspers , Nicole Van Luijk , Peter Jan Punt
IPC分类号： C12P7/46 , C12N9/88 , C12N1/00 , C12N15/63 , C07H21/04
CPC分类号： C12N9/88 , C12P7/46
摘要： The invention relates to the production of itaconic acid in micro-organisms by introducting into a suitable host cell a gene coding for the enzyme cis-aconitic acid decarboxylase, preferably derived from A. terreus. Further part of the invention are host cells, preferably from A. niger, provided with the above mentioned genes.
摘要翻译：本发明涉及通过向合适的宿主细胞中引入编码优选来源于土曲霉的顺式乌头酸脱羧酶的基因而在微生物中生产衣康酸。本发明的另一部分是具有上述基因的宿主细胞，优选来自黑曲霉。

3. 发明申请

US20080113872A1 Classification of Organisms Based on Genome Representing Arrays 审中-公开
标题翻译：基于表达阵列基因组的生物分类
公开(公告)号：US20080113872A1
公开(公告)日：2008-05-15
申请号：US11579025
申请日：2005-04-29
申请人： Frank Henri Johan Schuren , Martinus Petrus Maria Caspers , Bianca Johanna Catherina Van der Werff-van der Vat , Roy Christiaan Montijn
发明人： Frank Henri Johan Schuren , Martinus Petrus Maria Caspers , Bianca Johanna Catherina Van der Werff-van der Vat , Roy Christiaan Montijn
IPC分类号： C40B30/04 , C40B50/06
CPC分类号： C12Q1/689 , C12Q1/6837 , C12Q1/6888 , G16B25/00 , C12Q2565/513
摘要： The invention relates to a method of preparing clusters of reference hybridization patterns for a sample nucleic acid, comprising providing an array comprising a plurality of nucleic acid molecules, wherein said plurality of nucleic acid molecules is derived from at least two different sources, providing at least two different reference hybridization patterns by hybridizing said array with at least two different reference nucleic acids, wherein the sources of said at least two different reference nucleic acids are separable into at least two groups on the basis of a value for at least one phenotypic parameter, and clustering the reference hybridization patterns by unsupervised multivariate analysis. The method further provides a method for typing sample nucleic acid, comprising providing at least two different clusters of reference hybridization patterns for a sample nucleic acid by using a method according to the invention, hybridizing the same array as used for preparing the reference hybridization patterns with sample nucleic acid to obtain a sample hybridization pattern, and assigning the sample hybridization pattern to one of said at least two different clusters of reference hybridization patterns.
摘要翻译：本发明涉及制备用于样品核酸的参考杂交模式簇的方法，其包括提供包含多个核酸分子的阵列，其中所述多个核酸分子衍生自至少两个不同的来源，至少提供通过将所述阵列与至少两种不同的参考核酸杂交，其中所述至少两种不同参考核酸的来源可根据至少一种表型参数的值可分离成至少两个组，两种不同的参考杂交模式，并通过无监督的多变量分析对参考杂交模式进行聚类。该方法进一步提供了一种用于分型样品核酸的方法，其包括通过使用根据本发明的方法提供用于样品核酸的至少两个不同的参考杂交模式簇，将用于制备参考杂交模式的相同阵列与样品核酸以获得样品杂交模式，并将所述样品杂交模式分配给所述至少两个不同的参考杂交模式簇之一。

4. 发明申请

US20070289034A1 Control of Programmed Death(Pcd) in Plants 审中-公开
标题翻译：植物中程序死亡（Pcd）的控制
公开(公告)号：US20070289034A1
公开(公告)日：2007-12-13
申请号：US10589652
申请日：2005-02-17
申请人： Henricus Adriaan Korthout , Martinus Petrus Maria Caspers , Mei Wang
发明人： Henricus Adriaan Korthout , Martinus Petrus Maria Caspers , Mei Wang
IPC分类号： C12N15/90 , A01H1/00 , A01H5/00 , C12N1/20 , C12N1/21 , C12N15/82 , C12N15/87
CPC分类号： C12N9/0008 , C12N15/8263
摘要： The invention relates to a method of controlling programmed cell death in plants. In one aspects the present invention relates to such a method wherein a transgenic plant is produced that is less susceptible to stress-induced programmed cell death. The invention thus provides a method for controlling programmed cell death in a plant or plant-part comprising modifying the activity and/or expression of 2-oxoglutarate dehydrogenase-homologous protein in the cells of said plant or plant-part.
摘要翻译：本发明涉及一种控制植物中程序性细胞死亡的方法。在一个方面，本发明涉及这样一种方法，其中产生对应激诱导的程序性细胞死亡较不敏感的转基因植物。因此，本发明提供了控制植物或植物部分程序性细胞死亡的方法，包括修饰所述植物或植物部分的细胞中2-氧戊二酸脱氢酶同源蛋白的活性和/或表达。

5. 发明授权

US06031155A Arabinoxylan degradation 失效
标题翻译：阿拉伯木聚糖降解
公开(公告)号：US06031155A
公开(公告)日：2000-02-29
申请号：US869696
申请日：1997-06-05
申请人： Verena Cameron-Mills , Finn Lok , Catharina Maria Cornelia Sinjorgo , Ronald Tako Marinus van den Dool , Martinus Petrus Maria Caspers , Maria Joanna van Zeijl-van der Valk
发明人： Verena Cameron-Mills , Finn Lok , Catharina Maria Cornelia Sinjorgo , Ronald Tako Marinus van den Dool , Martinus Petrus Maria Caspers , Maria Joanna van Zeijl-van der Valk
IPC分类号： C12N9/24 , C12N15/82 , C12N5/04 , C12N15/29 , C12N15/81
CPC分类号： C12Y302/01008 , C12N15/8246 , C12N9/2482 , C12Y302/01001
摘要： A genomic nucleic acid sequence encoding a 62 kDa barley endoxylanase has been isolated and characterized. The genomic DNA sequences are used to transform plant cells for expression of enhanced amounts of active endoxylanase.
摘要翻译：已经分离并表征了编码62kDa大麦木聚糖酶的基因组核酸序列。基因组DNA序列用于转化植物细胞以表达增加量的活性内切木聚糖酶。

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