专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20120027694A1 INDUCIBLE RELEASE VEHICLES 有权
标题翻译：可消除泄漏车辆
公开(公告)号：US20120027694A1
公开(公告)日：2012-02-02
申请号：US13268108
申请日：2011-10-07
申请人： Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn , Johannes Wilhelmus Timmermans , Theodoor Maximiliaan Slaghek , Jacobus Johannes Frederik van Veen , Johannes Wilhelmus Leonardus Boumans
发明人： Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn , Johannes Wilhelmus Timmermans , Theodoor Maximiliaan Slaghek , Jacobus Johannes Frederik van Veen , Johannes Wilhelmus Leonardus Boumans
IPC分类号： A61K9/68 , A61K38/00 , A61K47/42 , A01P1/00 , A61K47/38 , A61P17/10 , A01P3/00 , A61L9/01 , A61K47/36
CPC分类号： A61L15/46 , A01N25/10 , A61L2300/208 , A61L2300/404 , A61L2300/604
摘要： This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.
摘要翻译：本发明涉及由交联的碳水化合物或蛋白质和活性成分组成的诱导释放载体。释放是由外部刺激引起的，例如酶如淀粉酶。这种载体可特别用于防止微生物衰变或抵抗微生物感染的应用中。其他用途是用于口服应用，例如提供抗龋齿或调味化合物以及用于制药和/或营养保健应用。

2. 发明申请

US20090192221A1 CARBAMATE ANTIBIOTICS 有权
标题翻译：碳酸盐抗生素
公开(公告)号：US20090192221A1
公开(公告)日：2009-07-30
申请号：US12097843
申请日：2006-12-21
申请人： Frank Henri Johan Schuren , Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn
发明人： Frank Henri Johan Schuren , Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn
IPC分类号： A61K31/235 , C07C271/00
CPC分类号： C07C271/28 , C07C311/53
摘要： The invention relates to the field of antibiotic compositions, both inside and outside the medical field. Presented is a new class of antibiotic compounds around the lead compound (3,4-dichloro-phenyl)-carbamic acid 2-isobutoxycarbonylamino-1-methyl-ethyl ester, which are especially useful for combating infections with gram-positive bacteria and especially MRSA.
摘要翻译：本发明涉及医疗领域内外的抗生素组合物领域。提出了一类新型的抗生素化合物，主要化合物（3,4-二氯 - 苯基） - 氨基甲酸2-异丁氧基羰基氨基-1-甲基 - 乙基酯，特别适用于抗革兰氏阳性菌感染，特别是MRSA 。

3. 发明授权

US08415105B2 Method of detecting pathogenic Legionella strains 失效
标题翻译：检测病原性军团菌菌株的方法
公开(公告)号：US08415105B2
公开(公告)日：2013-04-09
申请号：US12521119
申请日：2007-12-28
申请人： Frank Henri Johan Schuren , Roy Christiaan Montijn , Henricus Matheus Wilhelmus Maria Thijssen
发明人： Frank Henri Johan Schuren , Roy Christiaan Montijn , Henricus Matheus Wilhelmus Maria Thijssen
IPC分类号： C12Q1/68 , C07H21/02 , C07H21/04
CPC分类号： C12Q1/689 , Y02A50/451
摘要： The invention relates to a method of detecting pathogenic Legionella pneumophila strains by hybridizing genomic DNA of a sample suspected to contain Legionella to two or five specific sequence markers, as identified by MARKER NO. 1 through MARKER NO. 5 or homologues thereof. The invention further relates to a kit of parts comprising an array and reference materials for performing a method of the invention.
摘要翻译：本发明涉及通过将怀疑含有军团菌的样品的基因组DNA与MARKER NO鉴定的两个或五个特异性序列标记杂交来检测致病性嗜肺军团菌菌株的方法。 1通过标记号 5或其同系物。本发明还涉及包括用于执行本发明的方法的阵列和参考材料的部件套件。

4. 发明申请

US20100130509A1 NOVEL ANTIBIOTICS 审中-公开
标题翻译：新型抗生素
公开(公告)号：US20100130509A1
公开(公告)日：2010-05-27
申请号：US12594014
申请日：2008-04-03
申请人： Frank Henri Johan Schuren , Roy Christiaan Montijn
发明人： Frank Henri Johan Schuren , Roy Christiaan Montijn
IPC分类号： A61K31/496 , A61K31/4468 , A61K31/4439 , A61K31/41 , C07D403/12 , C07D401/12 , C07D257/04 , A61P31/04
CPC分类号： C07D257/04 , C07D401/14
摘要： The invention relates to the field of antibiotic compositions, both inside and outside the medical field. Presented is a new class of antibiotic compounds, variants of bis(1-aryl-5-tetrazolyl)methanes, which are especially useful for combating infections with gram-positive bacteria and especially MRSA.
摘要翻译：本发明涉及医疗领域内外的抗生素组合物领域。提出了一类新的抗生素化合物，双（1-芳基-5-四唑基）甲烷的变体，其特别可用于抗革兰氏阳性菌特别是MRSA的感染。

5. 发明申请

US20080113872A1 Classification of Organisms Based on Genome Representing Arrays 审中-公开
标题翻译：基于表达阵列基因组的生物分类
公开(公告)号：US20080113872A1
公开(公告)日：2008-05-15
申请号：US11579025
申请日：2005-04-29
申请人： Frank Henri Johan Schuren , Martinus Petrus Maria Caspers , Bianca Johanna Catherina Van der Werff-van der Vat , Roy Christiaan Montijn
发明人： Frank Henri Johan Schuren , Martinus Petrus Maria Caspers , Bianca Johanna Catherina Van der Werff-van der Vat , Roy Christiaan Montijn
IPC分类号： C40B30/04 , C40B50/06
CPC分类号： C12Q1/689 , C12Q1/6837 , C12Q1/6888 , G16B25/00 , C12Q2565/513
摘要： The invention relates to a method of preparing clusters of reference hybridization patterns for a sample nucleic acid, comprising providing an array comprising a plurality of nucleic acid molecules, wherein said plurality of nucleic acid molecules is derived from at least two different sources, providing at least two different reference hybridization patterns by hybridizing said array with at least two different reference nucleic acids, wherein the sources of said at least two different reference nucleic acids are separable into at least two groups on the basis of a value for at least one phenotypic parameter, and clustering the reference hybridization patterns by unsupervised multivariate analysis. The method further provides a method for typing sample nucleic acid, comprising providing at least two different clusters of reference hybridization patterns for a sample nucleic acid by using a method according to the invention, hybridizing the same array as used for preparing the reference hybridization patterns with sample nucleic acid to obtain a sample hybridization pattern, and assigning the sample hybridization pattern to one of said at least two different clusters of reference hybridization patterns.
摘要翻译：本发明涉及制备用于样品核酸的参考杂交模式簇的方法，其包括提供包含多个核酸分子的阵列，其中所述多个核酸分子衍生自至少两个不同的来源，至少提供通过将所述阵列与至少两种不同的参考核酸杂交，其中所述至少两种不同参考核酸的来源可根据至少一种表型参数的值可分离成至少两个组，两种不同的参考杂交模式，并通过无监督的多变量分析对参考杂交模式进行聚类。该方法进一步提供了一种用于分型样品核酸的方法，其包括通过使用根据本发明的方法提供用于样品核酸的至少两个不同的参考杂交模式簇，将用于制备参考杂交模式的相同阵列与样品核酸以获得样品杂交模式，并将所述样品杂交模式分配给所述至少两个不同的参考杂交模式簇之一。

6. 发明授权

US08771650B2 Inducible release vehicles 有权
标题翻译：诱导释放车辆
公开(公告)号：US08771650B2
公开(公告)日：2014-07-08
申请号：US13268108
申请日：2011-10-07
申请人： Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn , Johannes Wilhelmus Timmermans , Theodoor Maximiliaan Slaghek , Jacobus Johannes Frederik van Veen , Johannes Wilhelmus Leonardus Boumans
发明人： Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn , Johannes Wilhelmus Timmermans , Theodoor Maximiliaan Slaghek , Jacobus Johannes Frederik van Veen , Johannes Wilhelmus Leonardus Boumans
IPC分类号： A01P3/00 , A61K38/00 , A61P17/10 , A61K9/16 , A01N63/00 , A61K9/68 , A61K47/36 , A61Q15/00 , A61Q19/00 , A01N25/00 , A23L1/22 , A01N25/04 , A61K47/38 , A01P1/00 , A01N25/10 , A61K47/42 , A61L9/01
CPC分类号： A61L15/46 , A01N25/10 , A61L2300/208 , A61L2300/404 , A61L2300/604
摘要： This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.
摘要翻译：本发明涉及由交联的碳水化合物或蛋白质和活性成分组成的诱导释放载体。释放是由外部刺激引起的，例如酶如淀粉酶。这种载体可特别用于防止微生物衰变或抵抗微生物感染的应用中。其他用途是用于口服应用，例如提供抗龋齿或调味化合物以及用于制药和/或营养保健应用。

7. 发明申请

US20100099577A1 METHOD OF DETECTING PATHOGENIC LEGIONELLA STRAINS 失效
标题翻译：检测病原性菌株的方法
公开(公告)号：US20100099577A1
公开(公告)日：2010-04-22
申请号：US12521119
申请日：2007-12-28
申请人： Frank Henri Johan Schuren , Roy Christiaan Montijn , Henricus Matheus Wilhelmus Maria Thijssen
发明人： Frank Henri Johan Schuren , Roy Christiaan Montijn , Henricus Matheus Wilhelmus Maria Thijssen
IPC分类号： C40B40/06 , C12Q1/68
CPC分类号： C12Q1/689 , Y02A50/451
摘要： The invention relates to a method of detecting pathogenic Legionella pneumophila strains by hybridizing genomic DNA of a sample suspected to contain Legionella to two or five specific sequence markers, as identified by MARKER NO. 1 through MARKER NO. 5 or homologues thereof. The invention further relates to a kit of parts comprising an array and reference materials for performing a method of the invention.
摘要翻译：本发明涉及通过将怀疑含有军团菌的样品的基因组DNA与MARKER NO鉴定的两个或五个特异性序列标记杂交来检测致病性嗜肺军团菌菌株的方法。 1通过标记号 5或其同系物。本发明还涉及包括用于执行本发明的方法的阵列和参考材料的部件套件。

8. 发明申请

US20080280964A1 Novel Antibiotics Comprising Bis(1-Aryl-5-Tetrazolyl)Methane Derivatives 有权
标题翻译：包含双（1-芳基-5-四唑基）甲烷衍生物的新型抗生素
公开(公告)号：US20080280964A1
公开(公告)日：2008-11-13
申请号：US12088299
申请日：2006-09-29
申请人： Frank Henri Johan Schuren , Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn
发明人： Frank Henri Johan Schuren , Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn
IPC分类号： A61K31/41 , C07D403/06 , A61P31/04
CPC分类号： C07D403/06 , A61K31/41
摘要： The invention relates to the field of antibiotic compositions, both inside and outside the medical field. Presented is a new class of antibiotic compounds, the bis(1-aryl-5-tetrazolyl)methanes, which are especially useful for combating infections with gram-positive bacteria and especially MRSA.
摘要翻译：本发明涉及医疗领域内外的抗生素组合物领域。提出了一类新型的抗生素化合物，即双（1-芳基-5-四唑基）甲烷，特别适用于抗革兰氏阳性菌特别是MRSA的感染。

9. 发明授权

US08986946B2 Real-time method for the detection of viable micro-organisms 有权
标题翻译：用于检测可行微生物的实时方法
公开(公告)号：US08986946B2
公开(公告)日：2015-03-24
申请号：US12809566
申请日：2008-12-19
申请人： Remco Kort , Frank Henri Johan Schuren , Roy Christiaan Montijn
发明人： Remco Kort , Frank Henri Johan Schuren , Roy Christiaan Montijn
IPC分类号： C12Q1/18 , C12Q1/04 , G01N21/64 , C12Q1/06 , G01N21/80
CPC分类号： C12Q1/04 , G01N21/6428 , G01N21/80
摘要： The invention relates to a method for real-time detection of viable microorganisms comprising: a. addition of a cell-permeable, phototautomeric compound to a micro-organism or other living cell; and b. measuring the fluorescent emission of said phototautomeric compound. Preferably the phototautomeric compound is salicylic acid, 2-hydroxy-1-naphtoic acid or 1-hydroxy-2-naphtoic acid. Further, the assay can he used to assess the antibiotic effect of a test compound. This test can be used as a high—throughput screening for compounds with antibiotic activity. Also part of the invention is the use of a cell permeable phototautomeric compound in a method for determining the viability of micro-organisms and for assessing the antibiotic effect of a test compound.
摘要翻译：本发明涉及一种用于实时检测活微生物的方法，包括：a。向微生物或其他活细胞中加入细胞可渗透的光敏化合物; 和b。测量所述光自由基化合物的荧光发射。优选的光敏化合物是水杨酸，2-羟基-1-萘甲酸或1-羟基-2-萘甲酸。此外，他可以使用该测定来评估测试化合物的抗生素效果。该测试可用作具有抗生素活性的化合物的高通量筛选。本发明的一部分也是在测定微生物活力的方法中以及用于评估测试化合物的抗生素效果的方法中使用细胞可渗透的光致敏化合物。

10. 发明授权

US08771649B2 Inducible release vehicles 有权
标题翻译：诱导释放车辆
公开(公告)号：US08771649B2
公开(公告)日：2014-07-08
申请号：US10558816
申请日：2004-05-28
申请人： Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn , Johannes Wilhelmus Timmermans , Theodoor Maximiliaan Slaghek , Jacobus Johannes Frederick van Veen , Johannes Wilhelmus Leonardus Boumans
发明人： Henricus Matheus Wilhelmus Maria Thijssen , Roy Christiaan Montijn , Johannes Wilhelmus Timmermans , Theodoor Maximiliaan Slaghek , Jacobus Johannes Frederick van Veen , Johannes Wilhelmus Leonardus Boumans
IPC分类号： A01P3/00 , A61K38/00 , A61P17/10 , A61K9/16 , A01N63/00 , A61K9/68 , A61K47/36 , A61Q15/00 , A61Q19/00 , A01N25/00 , A23L1/22 , A01N25/04 , A61K47/38 , A01P1/00 , A01N25/10 , A61K47/42 , A61L9/01
CPC分类号： A61L15/46 , A01N25/10 , A61L2300/208 , A61L2300/404 , A61L2300/604
摘要： This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing antdaries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.
摘要翻译：本发明涉及由交联的碳水化合物或蛋白质和活性成分组成的诱导释放载体。释放是由外部刺激引起的，例如酶如淀粉酶。这种载体可以特别用于防止微生物衰变或抵抗微生物感染的应用中。其他用途用于口服应用，例如提供抗肿瘤剂或调味剂化合物，以及药物和/或营养品应用。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式