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1. 发明授权

US07691085B2 Syringe interfaces and adapters for use with medical injectors 有权
标题翻译：用于医疗注射器的注射器接口和适配器
公开(公告)号：US07691085B2
公开(公告)日：2010-04-06
申请号：US10295297
申请日：2002-11-15
申请人： James Albert Dedig , Frank A. Lazzaro , Kevin P. Cowan , Mark W. Hitchins , Charles J. Mutschler , James R. Neill
发明人： James Albert Dedig , Frank A. Lazzaro , Kevin P. Cowan , Mark W. Hitchins , Charles J. Mutschler , James R. Neill
IPC分类号： A61M5/20
CPC分类号： A61M5/14546 , A61M5/1456 , A61M5/1458 , A61M2205/58 , Y10S128/01
摘要： A syringe interface includes a top opening into which a syringe can be loaded, a first retaining member positioned on one side of the opening and a second retaining member positioned on a second side of the opening. The first retaining member and the second retaining member abut a forward facing abutment surface of a syringe flange on the syringe generally symmetrically. The syringe interface further includes a cradle, at least one engagement member to abut a forward facing abutment surface of a syringe flange, and a carriage slidably disposed within the cradle. The carriage includes a connector to form a releasable connection with a plunger or plunger extension of the syringe and a drive member of the injector. The connector includes a plurality of flexing capture members that flex radially outward to connect to a flange on the rear of the plunger or plunger extension of the syringe when the carriage is moved forward within the syringe interface. The syringe interface may further include a connector on a rear portion thereof to connect to the injector.
摘要翻译：注射器接口包括可以装载注射器的顶部开口，位于开口的一侧上的第一保持构件和位于开口的第二侧上的第二保持构件。第一保持构件和第二保持构件大致对称地抵靠注射器凸缘的朝前的抵靠表面。注射器接口还包括支架，至少一个接合构件以抵靠注射器凸缘的前向对置的表面，以及可滑动地设置在支架内的托架。托架包括连接器，以形成与注射器的柱塞或柱塞延伸部和注射器的驱动构件的可释放连接。连接器包括多个弯曲捕获构件，当滑架在注射器接口内向前移动时，径向向外弯曲以连接到注射器的柱塞或柱塞延伸部的后部上的凸缘。注射器接口还可以包括在其后部分上连接到喷射器的连接器。

2. 发明授权

US5873861A Plunger systems 失效
公开(公告)号：US5873861A
公开(公告)日：1999-02-23
申请号：US748258
申请日：1996-11-12
申请人： Mark W. Hitchins , Edward J. Rhinehart , David M. Reilly , Anthony S. McCoppin , Robert J. Masarik
发明人： Mark W. Hitchins , Edward J. Rhinehart , David M. Reilly , Anthony S. McCoppin , Robert J. Masarik
IPC分类号： A61M5/145 , A61M25/18 , A61M5/00
CPC分类号： A61M5/14546 , A61M5/14566 , A61M5/31515
摘要： The plunger systems for use in an injector-actuated syringe of the present invention include a dynamic wedge seal which improves the sealing engagement between the plunger cover and syringe barrel, and flexible capture members extending from the rear surface of the plunger which permit the engagement and disengagement of the plunger from the injector drive means at any plunger position within the syringe. Further, the plunger systems include a contrast saving tip which expells the injection liquid from the syringe tip.

3. 发明授权

US08721596B2 Front-loading syringe adapted to releasably engage a medical injector regardless of the orientation of the syringe with respect to the injector 有权
标题翻译：适于可释放地接合医疗注射器的前装载注射器，而不管注射器相对于注射器的取向如何
公开(公告)号：US08721596B2
公开(公告)日：2014-05-13
申请号：US10668643
申请日：2003-09-23
申请人： Mark Trocki , Mark W. Hitchins , Kevin P. Cowan , Edward J. Rhinehart
发明人： Mark Trocki , Mark W. Hitchins , Kevin P. Cowan , Edward J. Rhinehart
IPC分类号： A61M37/00
CPC分类号： A61M5/14546 , A61M5/14566 , A61M2205/60 , A61M2205/6063 , A61M2205/6072
摘要： A syringe for use with an injector includes a body having a rear end and a front end, a plunger movably disposed within the body, an attachment member associated with the body and adapted to releasably engage a syringe retaining mechanism of the injector regardless of the orientation of the syringe with respect to the injector, and an encoding device operable to provide syringe information to the injector.
摘要翻译：用于注射器的注射器包括具有后端和前端的主体，可移动地设置在主体内的柱塞，与主体相关联并适于可释放地接合注射器的注射器保持机构而不管取向如何相对于注射器的注射器，以及可操作以向注射器提供注射器信息的编码装置。

4. 发明授权

US07540856B2 Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector 有权
标题翻译：正面装载医用喷射器适于可释放地接合注射器，而与注射器相对于注射器的取向无关
公开(公告)号：US07540856B2
公开(公告)日：2009-06-02
申请号：US10668673
申请日：2003-09-23
申请人： Mark W. Hitchins , Kevin P. Cowan , Francis J. Sciulli , Robert D. Parks
发明人： Mark W. Hitchins , Kevin P. Cowan , Francis J. Sciulli , Robert D. Parks
IPC分类号： A61M5/00 , A61M1/00
CPC分类号： A61M5/14546 , A61M5/14566 , A61M2205/60 , A61M2205/6063 , A61M2205/6072
摘要： An injector for injecting fluid from a syringe mounted thereon includes a housing, a drive member at least partially disposed within the housing and operable to engage a plunger of the syringe, and a syringe retaining mechanism associated with the housing. The syringe retaining mechanism is adapted to releasably engage the syringe regardless of the orientation of the syringe with respect to the injector. Further, the retaining mechanism is preferably movable upon rotation of the syringe between a relaxed state, where the syringe is engaged by the retaining mechanism, and a tensioned state, where the syringe is released from the retaining mechanism.
摘要翻译：用于从安装在其上的注射器注射流体的注射器包括壳体，至少部分地设置在壳体内并可操作以接合注射器的柱塞的驱动构件和与壳体相关联的注射器保持机构。注射器保持机构适于可释放地接合注射器，而与注射器相对于注射器的取向无关。此外，保持机构优选地可以在注射器在注射器被保持机构接合的松弛状态和注射器从保持机构释放之间的张紧状态下旋转时移动。

5. 发明授权

US5947935A Syringes, syringe plungers and injector systems 失效
标题翻译：注射器，注射器柱塞和注射器系统
公开(公告)号：US5947935A
公开(公告)日：1999-09-07
申请号：US978226
申请日：1997-11-25
申请人： Edward J. Rhinehart , David M. Reilly , Mark W. Hitchins , Anthony S. McCoppin
发明人： Edward J. Rhinehart , David M. Reilly , Mark W. Hitchins , Anthony S. McCoppin
IPC分类号： A61M5/145 , A61M25/18 , A61M25/00
CPC分类号： A61M5/14546 , A61M5/14566 , A61M5/31515
摘要： The present invention provides a connection mechanism adapted to make a releasable connection between a syringe plunger and a drive member of an injector. The drive member is preferably movable in a generally reciprocal linear manner to control movement of the plunger within the syringe. The connection mechanism comprises at least one capture member attached to the plunger. The capture member forms a releasable connection with the drive member upon contact of the drive member during linear forward motion of the drive member when the capture member is rotated relative to the drive member to an engagement position. The capture member is further adapted to disconnect from the drive member upon rotation of the capture member relative to the drive member to a disengagement position.
摘要翻译：本发明提供了一种适于在注射器柱塞和注射器的驱动构件之间进行可释放连接的连接机构。驱动构件优选地以大致往复的线性方式移动以控制柱塞在注射器内的移动。连接机构包括附接到柱塞的至少一个捕获构件。当捕获构件相对于驱动构件旋转到接合位置时，捕获构件在驱动构件的线性向前运动期间与驱动构件接触时形成与驱动构件的可释放连接。捕获构件还适于在捕获构件相对于驱动构件旋转到脱离位置时与驱动构件断开连接。

6. 发明授权

US09242040B2 Syringe assemblies, methods of forming syringe assemblies and adapters for forming syringe assemblies 有权
标题翻译：注射器组件，形成注射器组件的方法和用于形成注射器组件的适配器
公开(公告)号：US09242040B2
公开(公告)日：2016-01-26
申请号：US12766411
申请日：2010-04-23
申请人： Edward P. Liscio , Luis Castillo , Michael McNeill , Mark W. Hitchins
发明人： Edward P. Liscio , Luis Castillo , Michael McNeill , Mark W. Hitchins
IPC分类号： A61M5/145
CPC分类号： A61M5/31565 , A61M5/14546 , A61M2005/14553 , A61M2005/3125 , A61M2205/3306 , A61M2207/00 , Y10T29/49826
摘要： Syringe assemblies and adapters for syringes that attach to and allow non-native syringes to be accepted by injectors having injector syringe interfaces adapted for particular types of syringes are described herein. Methods of forming the syringe assemblies, and kits including the syringe adapters which enable a non-native syringe to be operably attached to an injector are also described.
摘要翻译：本文描述了用于注射器的注射器组件和适配器，其连接到并且允许非本地注射器被具有适于特定类型的注射器的注射器针入口的注射器接受。还描述了形成注射器组件的方法以及包括使得非天然注射器可操作地连接到注射器的注射器适配器的试剂盒。

7. 发明申请

US20110106015A1 SYRINGE ASSEMBLIES, METHODS OF FORMING SYRINGE ASSEMBLIES AND ADAPTERS FOR FORMING SYRINGE ASSEMBLIES 有权
标题翻译：注射器组件，形成SYRINGE组件的方法和用于形成SYRINGE组件的适配器
公开(公告)号：US20110106015A1
公开(公告)日：2011-05-05
申请号：US12766411
申请日：2010-04-23
申请人： Edward P. Liscio , Luis Castillo , Michael McNeill , Mark W. Hitchins
发明人： Edward P. Liscio , Luis Castillo , Michael McNeill , Mark W. Hitchins
IPC分类号： A61M5/31 , B23P17/04
CPC分类号： A61M5/31565 , A61M5/14546 , A61M2005/14553 , A61M2005/3125 , A61M2205/3306 , A61M2207/00 , Y10T29/49826
摘要： A syringe assembly connectible to an injector including a syringe interface and a drive member includes a syringe portion including a barrel section to contain fluid to be pressurized and an outlet in fluid connection with the barrel section. The syringe assembly also includes an adapter formed separately from the syringe portion and including a plurality of sections. At least two sections of the plurality of sections are engageable to nonremovably connect the adapter to the syringe portion. In a number of embodiment, the adapter includes only two section the engage to nonremovably connect the adapter to the syringe portion. The adapter further includes a mounting mechanism adapted to be connected to the injector syringe interface. The adapter can also include a passage in operative connection with the barrel section after connection of the adapter to the syringe portion so that upon connection of the adapter with the syringe portion, the drive member can pass through the passage to impart motion to a plunger slidably positionable within the barrel section.
摘要翻译：可连接到包括注射器接口和驱动构件的注射器的注射器组件包括注射器部分，其包括用于容纳待加压流体的筒体部分和与筒部分流体连接的出口。注射器组件还包括与注射器部分分开形成并包括多个部分的适配器。多个部分中的至少两个部分可接合以将适配器不可移除地连接到注射器部分。在多个实施例中，适配器仅包括接合以将适配器不可移除地连接到注射器部分的两个部分。适配器还包括适于连接到注射器注射器接口的安装机构。适配器还可以包括在将适配器连接到注射器部分之后与筒体部分可操作地连接的通道，使得当适配器与注射器部分连接时，驱动构件可以穿过通道以使滑动件可定位在桶部分内。

8. 发明授权

US5944694A Prefillable syringes and injectors for use therewith 失效
标题翻译：预先使用的注射器和注射器
公开(公告)号：US5944694A
公开(公告)日：1999-08-31
申请号：US748230
申请日：1996-11-12
申请人： Mark W. Hitchins , Edward J. Rhinehart , Robert J. Masarik
发明人： Mark W. Hitchins , Edward J. Rhinehart , Robert J. Masarik
IPC分类号： A61M5/145 , A61M37/00
CPC分类号： A61M5/14546 , A61M5/14566
摘要： The present invention provides prefillable syringes and injectors for use therewith that expand and/or facilitate a variety of medical procedures involving the injection of a liquid medium. In several embodiments, the present syringes and injectors enable the use of current syringe materials at higher pressures than previously attainable or the use of other materials not previously usable with current high pressure-syringe and injector designs. In one embodiment, a syringe comprises an elongated cylindrical main body having a first pair and a second pair of mounting flanges encompassing collectively an arcuate length equal to at least approximately 180.degree. of the circumference of the rear portion of the cylindrical main body for releasably mounting the syringe in a desired position relative to the front wall of the injector housing. Injectors for use with such syringes comprise a housing having a front wall and a retainer on the front wall which cooperates with the first and second pairs of mounting flanges of the syringe to releasably mount the syringe on the injector.
摘要翻译：本发明提供了可与之一起使用的可预充注射器和注射器，其扩展和/或促进涉及注射液体介质的各种医疗过程。在几个实施例中，本发明的注射器和注射器使得能够以比先前可获得的更高的压力使用当前的注射器材料，或者使用以前不能用于当前高压注射器和注射器设计的其它材料。在一个实施例中，注射器包括细长的圆柱形主体，其具有第一对和第二对安装凸缘，其共同包含等于圆柱形主体的后部的圆周的至少大约180度的弓形长度，用于可释放地安装注射器相对于注射器壳体的前壁处于期望的位置。用于这种注射器的注射器包括具有在前壁上的前壁和保持器的壳体，其与注射器的第一和第二对安装凸缘配合以将注射器可释放地安装在注射器上。

9. 发明授权

US06984222B1 Plunger systems 失效
公开(公告)号：US06984222B1
公开(公告)日：2006-01-10
申请号：US09436612
申请日：1999-11-09
申请人： Mark W. Hitchins , Edward J. Rhinehart , David M. Reilly , Anthony S. McCoppin , Thomas L. Dufalla , Robert J. Masarik
发明人： Mark W. Hitchins , Edward J. Rhinehart , David M. Reilly , Anthony S. McCoppin , Thomas L. Dufalla , Robert J. Masarik
IPC分类号： A61M5/315
CPC分类号： A61M5/14546 , A61M5/14566 , A61M5/1458
摘要： The plunger systems for use in an injector-actuated syringe of the present invention include a dynamic wedge seal which improves the sealing engagement between the plunger cover and syringe barrel, and flexible capture members extending from the rear surface of the plunger which permit the engagement and disengagement of the plunger from the injector drive means at any plunger position within the syringe. Further, the plunger systems include a contrast saving tip which expells the injection liquid from the syringe tip.

10. 发明授权

US06224577B1 Syringes and plungers for use therein 失效
标题翻译：注射器和柱塞用于其中
公开(公告)号：US06224577B1
公开(公告)日：2001-05-01
申请号：US09033264
申请日：1998-03-02
申请人： Salvatore J. Dedola , Mark W. Hitchins
发明人： Salvatore J. Dedola , Mark W. Hitchins
IPC分类号： A61M500
CPC分类号： A61M5/31513 , A61M2005/31521
摘要： The present invention provides a plunger for use in a syringe and a syringe comprising such a plunger. The plunger includes a pressure member extending around the circumference of a generally cylindrical body of the plunger. The pressure member is in substantially sealing contact with the plunger body. The pressure member is sufficiently flexible to be forced radially outwardly to exert force upon the inner wall of the syringe as a result of increased fluid pressure upon forward motion of the plunger. The pressure member thereby forms a substantially sealing engagement with the inner wall of the syringe. In one embodiment, the pressure member comprises a flange attached at a rearward portion of the flange to a body of the plunger. The flange extends forward and radially outward to form a circumferential channel between the flange and the body of the plunger. In another embodiment, the pressure member comprises a resilient O-ring seated in a seating formed around the circumference of the body of the plunger. The seating comprises a ramp portion having a forward radius that is smaller than a rearward radius thereof.
摘要翻译：本发明提供一种用于注射器的柱塞和包括这种柱塞的注射器。柱塞包括围绕柱塞的大致圆柱形主体的圆周延伸的压力构件。压力构件与柱塞本体基本上密封接触。由于柱塞向前运动时的流体压力增加，压力构件足够柔软以被迫径向向外施加到注射器的内壁上。因此，压力构件与注射器的内壁形成基本密封的接合。在一个实施例中，压力构件包括在凸缘的后部附接到柱塞的主体的凸缘。凸缘向前并径向向外延伸，以在凸缘和柱塞主体之间形成圆周通道。在另一个实施例中，压力构件包括位于围绕柱塞主体的圆周形成的座中的弹性O形环。座椅包括具有小于其后半径的前半径的斜坡部分。

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