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1. 发明申请

US20130172811A1 Systems and Methods of Delivering a Dilated Slurry to a Patient 有权
标题翻译：向患者提供稀释的浆液的系统和方法
公开(公告)号：US20130172811A1
公开(公告)日：2013-07-04
申请号：US13772849
申请日：2013-02-21
申请人： Arthur E. Uber, III , David M. Griffiths , David M. Reilly , Alan D. Hirschman , Kevin P. Cowan , Mark Trocki
发明人： Arthur E. Uber, III , David M. Griffiths , David M. Reilly , Alan D. Hirschman , Kevin P. Cowan , Mark Trocki
IPC分类号： A61M5/14 , A61M5/172
CPC分类号： A61M5/1407 , A61M5/14216 , A61M5/14236 , A61M5/1723 , A61M2202/09 , B01F7/00258 , B01F7/00566 , B01F7/00908 , B01F7/086 , B01F9/103 , B01F11/0071 , B01F11/0074 , B01F11/0082 , B01F11/025 , B01F13/002 , B01F13/0023 , B01F13/0818 , G06F19/00
摘要： A system for delivering a slurry to a patient includes a fluid, a material that is non-dissolvable or immiscible in the fluid, thereby forming a slurry, a container adapted to contain the slurry and a supernate of the slurry, the container defining an outlet through which the slurry is delivered to the patient, a fluidizing system associated with the container, a pressurizing mechanism adapted to create a pressure to cause the slurry contained within the container to flow for delivery to the patient and a control unit in communication with and adapted to control the fluidizing system and the pressurizing mechanism. The fluidizing system is adapted to effect dilation of the slurry while maintaining at least a portion of the supernate.
摘要翻译：用于将浆料递送到患者的系统包括流体，在流体中不可溶或不混溶的材料，从而形成浆料，适于容纳浆料的容器和浆料的上清液，容器限定出口通过其将浆料输送到患者，与容器相关联的流化系统，适于产生压力以使容纳在容器内的浆液流动以输送到患者的加压机构，以及与该患者连接并适应的控制单元以控制流化系统和加压机构。流化系统适于在保持至少一部分上清液的同时实现浆料的扩张。

2. 发明授权

US08414765B2 System for processing cells and container for use therewith 有权
标题翻译：用于处理细胞和容器的系统
公开(公告)号：US08414765B2
公开(公告)日：2013-04-09
申请号：US12732250
申请日：2010-03-26
申请人： Arthur E. Uber , Mark Trocki , Frederick W. Trombley
发明人： Arthur E. Uber , Mark Trocki , Frederick W. Trombley
IPC分类号： A61M5/31
CPC分类号： A61J1/1443 , A61J1/1456 , A61J1/1475 , A61M5/142 , A61M5/1723 , A61M5/3145 , A61M31/005 , B01L3/502 , B01L2300/044 , B01L2300/0681 , G06F19/3468
摘要： A system for processing cells is disclosed. The system may include a container having an inner wall, a plunger adapted to be slidably positioned within the container, at least one inlet port through which a fluid can enter the container, at least one outlet port through which a fluid can exit the container, at least one effluent port through which an effluent can exit the container, a first check valve in fluid connection with the inlet port and a second check valve in fluid connection with the effluent port. The plunger may include a filter that allows fluid to pass therethrough but prevents cells from passing therethrough. Rearward motion of the plunger may be adapted to draw fluid into the system via the inlet port and forward motion of the plunger may be adapted to force effluent out of the system via the effluent port.
摘要翻译：公开了一种用于处理单元的系统。该系统可以包括容器，其具有内壁，适于可滑动地定位在容器内的柱塞，至少一个入口，流体可以通过该入口进入容器，至少一个出口，流体可以通过该出口离开容器，至少一个流出物出口可以离开容器的第一止回阀，与入口端口流体连接的第一止回阀和与流出物端口流体连接的第二止回阀。柱塞可以包括允许流体通过其但防止细胞通过的过滤器。柱塞的向后运动可以适于通过入口将流体引入系统，并且柱塞的向前运动可以适于通过流出物端口将流出物强制流出系统。

3. 发明申请

US20110209764A1 Apparatus and Methods for Delivery of Fluid Injection Boluses to Patients and Handling Harmful Fluids 有权
标题翻译：流体注射液给患者和处理有害液体的装置和方法
公开(公告)号：US20110209764A1
公开(公告)日：2011-09-01
申请号：US12996520
申请日：2009-06-05
申请人： Arthur E. Uber , Mark Trocki , Marc A. Mabie , Larry McCutchan , George L. Siddoway , Kevin P. Cowan , Lisa M. Coates , John F. Kalafut , Aaron Hughes , David M. Griffiths , Peter Twichell , Julie Gulick
发明人： Arthur E. Uber , Mark Trocki , Marc A. Mabie , Larry McCutchan , George L. Siddoway , Kevin P. Cowan , Lisa M. Coates , John F. Kalafut , Aaron Hughes , David M. Griffiths , Peter Twichell , Julie Gulick
IPC分类号： F17D3/00 , B65D25/02
CPC分类号： A61N5/1007 , A61M5/007 , A61M5/16827 , A61M5/1785 , A61M2005/1402 , A61M2202/0225 , A61M2202/049 , A61M2206/11 , A61M2206/18 , Y10T137/0318
摘要： A hazardous fluid transport container and a hazardous fluid delivery system are disclosed. The hazardous fluid transport container includes a housing enclosing an at least partially shielded enclosure. First and second fluid path elements are disposed within the housing, with the first fluid path element and second fluid path element fluidly coupled together. A pump unit may be provided for dispensing fluid from the first and second fluid path elements optionally into a third fluid path element. Also, methods for priming the hazardous fluid transport container and for mitigating laminar flow injection bolus spreading are disclosed. Additionally, disclosed is a radioactive fluid transport container for a syringe or other container. The radioactive fluid transport container allows the syringe or container to be used in an injection procedure without removal from the container.
摘要翻译：公开了一种危险的流体输送容器和危险流体输送系统。危险流体输送容器包括封闭至少部分屏蔽的外壳的壳体。第一和第二流体通道元件设置在壳体内，第一流体路径元件和第二流体路径元件流体耦合在一起。可以提供泵单元，用于将流体从第一和第二流体路径元件任选地分配到第三流体路径元件中。此外，公开了用于引燃危险流体输送容器和减轻层流注射团块扩散的方法。此外，公开了一种用于注射器或其他容器的放射性流体输送容器。放射性流体输送容器允许注射器或容器在注射过程中使用而不从容器中取出。

4. 发明授权

US07475701B2 Valve systems and injector system including such valve systems 有权
标题翻译：阀系统和喷射器系统包括这种阀系统
公开(公告)号：US07475701B2
公开(公告)日：2009-01-13
申请号：US11420094
申请日：2006-05-24
申请人： Mark Trocki , David M. Reilly
发明人： Mark Trocki , David M. Reilly
IPC分类号： F16K11/00 , F16K7/12
CPC分类号： A61M39/24 , A61M5/14546 , A61M5/16827 , A61M39/223 , A61M39/228 , A61M2039/2473 , A61M2039/2486 , A61M2039/2493 , Y10T137/2567 , Y10T137/2569 , Y10T137/2572 , Y10T137/2622 , Y10T137/7838 , Y10T137/7843 , Y10T137/7849 , Y10T137/86726 , Y10T137/87338 , Y10T137/87555
摘要： A valve system for use in a system including a first source of a first pressurized fluid and a second source of a second pressurized fluid includes a valve housing including a first inlet port adapted to be placed in fluid connection with the first source, a second inlet port adapted to be placed in fluid connection with the second source and an outlet port. The valve system further includes a backflow prevention system to prevent flow of the first pressurized fluid through the second inlet and to prevent flow of the second pressurized fluid through the first inlet port. The valve system is adapted to provide a fluid path between at least the first inlet port and the outlet port to enable fluid to be drawn from the outlet port to the first inlet port. Several of the valve systems of the present invention provide for flow from the first inlet port to the outlet port and concurrent flow from the second inlet port to the outlet port.
摘要翻译：一种用于包括第一加压流体的第一源和第二加压流体的第二源的系统的阀系统包括阀壳体，其包括适于与第一源流体连接的第一入口端口，第二入口端口适于与第二源和出口端口流体连接。阀系统还包括防止流体流动的第一加压流体通过第二入口并防止第二加压流体通过第一入口流动的防回流系统。阀系统适于在至少第一入口和出口之间提供流体路径，以使流体能够从出口到第一入口端口被抽出。本发明的几个阀门系统提供从第一入口到出口的流动以及从第二入口到出口的并流。

5. 发明申请

US20060184124A1 Injectors, injector systems and methods for injecting fluids 有权
标题翻译：注射器，注射器系统和注射液体的方法
公开(公告)号：US20060184124A1
公开(公告)日：2006-08-17
申请号：US11336150
申请日：2006-01-21
申请人： Kevin Cowan , David Reilly , Joseph Fularz , Paul Swartz , Mark Trocki , David Mishler
发明人： Kevin Cowan , David Reilly , Joseph Fularz , Paul Swartz , Mark Trocki , David Mishler
IPC分类号： A61M37/00
CPC分类号： A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/16827 , A61M2005/14506
摘要： An injector for injection a fluid into a patient, including: a first pressurizing mechanism adapted to operatively connect with a first fluid container to pressurize fluid therein; at least a second pressurizing mechanism to operatively connect with a second fluid container to pressurize a fluid therein; a single drive; and a transmission to control how power from the drive is distributed to the first pressurizing mechanism of the first container and to the second pressurizing mechanism of the second container to control injection of fluid from the first container and from the second container. The drive can, for example, be an electric motor or other drive.
摘要翻译：一种用于将流体注射到患者体内的注射器，包括：第一加压机构，其适于与第一流体容器可操作地连接以对其中的流体加压; 至少第二加压机构，用于与第二流体容器可操作地连接以对其中的流体加压; 单个驱动器以及变速器，用于控制来自驱动器的动力如何分配到第一容器的第一加压机构和第二容器的第二加压机构，以控制来自第一容器和第二容器的流体的喷射。驱动器可以例如是电动机或其他驱动器。

6. 发明授权

US06733477B2 Syringes, syringe tubing and fluid transfer systems 有权
标题翻译：注射器，注射器管和流体传输系统
公开(公告)号：US06733477B2
公开(公告)日：2004-05-11
申请号：US09731108
申请日：2000-12-06
申请人： Kevin P. Cowan , Frederick W. Trombley, III , Mark Trocki , David M. Reilly
发明人： Kevin P. Cowan , Frederick W. Trombley, III , Mark Trocki , David M. Reilly
IPC分类号： A61M500
CPC分类号： A61M5/14546 , A61M5/385 , A61M2005/1403
摘要： A syringe includes a body and a plunger disposed therein. The body includes a nozzle formed therein and at least one hub member connected thereto or integrally formed thereon for holding an end of a connector tube. The connector tube includes two ends, each end preferably being connected to a respective hub member to retain the connector tube in contact with the syringe. Preferably, the syringe and the connector tube are packaged in a pre-connected condition for ease of use by the customer. Furthermore, flexible inlet tubing for connection to a syringe for filling the syringe with contrast media, for example, is described. The inlet tubing permits filling of the syringe from either a bag or a bottle and may remain attached to the syringe so that it forms at least a part of the connection to the patient. In addition, an apparatus for facilitating the purge of air from a connector tube that will ultimately be connected between a syringe and a patient is described. The apparatus includes a purging tube connected to the distal end of the connector tubing from the syringe. The purging tube includes a venting cap at its distal end. A flow inhibitor is positioned under the venting cap to cooperate with the venting cap by discouraging the discharge of fluid from the distal end of the purging tube while permitting the discharge of air therefrom.
摘要翻译：注射器包括主体和设置在其中的柱塞。主体包括形成在其中的喷嘴和与其连接或一体地形成在其上的至少一个毂构件，用于保持连接器管的端部。连接器管包括两个端部，每个端部优选地连接到相应的毂部件，以将连接器管保持与注射器接触。优选地，注射器和连接管被包装在预连接状态中，以便客户易于使用。此外，描述了用于连接到注射器的柔性入口管，用于例如用造影剂填充注射器。入口管允许从袋或瓶中填充注射器，并且可以保持附接到注射器，使得其形成与患者的连接的至少一部分。此外，描述了一种便于从最终连接在注射器和患者之间的连接管吹扫空气的装置。该装置包括从注射器连接到连接管的远端的清洗管。吹扫管在其远端包括通气盖。流动抑制剂位于排气盖下面，以与通气帽配合，通过阻止从清洗管的远端排出流体，同时允许排出空气。

7. 发明授权

US08721596B2 Front-loading syringe adapted to releasably engage a medical injector regardless of the orientation of the syringe with respect to the injector 有权
标题翻译：适于可释放地接合医疗注射器的前装载注射器，而不管注射器相对于注射器的取向如何
公开(公告)号：US08721596B2
公开(公告)日：2014-05-13
申请号：US10668643
申请日：2003-09-23
申请人： Mark Trocki , Mark W. Hitchins , Kevin P. Cowan , Edward J. Rhinehart
发明人： Mark Trocki , Mark W. Hitchins , Kevin P. Cowan , Edward J. Rhinehart
IPC分类号： A61M37/00
CPC分类号： A61M5/14546 , A61M5/14566 , A61M2205/60 , A61M2205/6063 , A61M2205/6072
摘要： A syringe for use with an injector includes a body having a rear end and a front end, a plunger movably disposed within the body, an attachment member associated with the body and adapted to releasably engage a syringe retaining mechanism of the injector regardless of the orientation of the syringe with respect to the injector, and an encoding device operable to provide syringe information to the injector.
摘要翻译：用于注射器的注射器包括具有后端和前端的主体，可移动地设置在主体内的柱塞，与主体相关联并适于可释放地接合注射器的注射器保持机构而不管取向如何相对于注射器的注射器，以及可操作以向注射器提供注射器信息的编码装置。

8. 发明申请

US20130211248A1 BLADDER SYRINGE FLUID DELIVERY SYSTEM 审中-公开
标题翻译： BLADDER SYRINGE流体输送系统
公开(公告)号：US20130211248A1
公开(公告)日：2013-08-15
申请号：US13881072
申请日：2011-10-25
申请人： Kevin P. Cowan , Raymond C. Hoffman , Charles A. Lang , Mark Trocki , Arthur E. Uber, III , Joseph C. Mator , Edward P. Liscio , Bernard J. Hobi , L. Robert Crouthamel , Glen P. Williams , Vincent S. Rossitto , Jaroslaw Wlodarczyk , Matthew Schrauder
发明人： Kevin P. Cowan , Raymond C. Hoffman , Charles A. Lang , Mark Trocki , Arthur E. Uber, III , Joseph C. Mator , Edward P. Liscio , Bernard J. Hobi , L. Robert Crouthamel , Glen P. Williams , Vincent S. Rossitto , Jaroslaw Wlodarczyk , Matthew Schrauder
IPC分类号： A61M5/00
CPC分类号： A61M5/007 , A61M5/1452 , A61M5/148 , A61M5/2425 , A61M5/31511
摘要： A bladder syringe for a fluid delivery system includes a cylindrical body, a cap-bladder assembly, a plunger element disposed in the cylindrical body, and a mounting assembly to secure the cap-bladder assembly to the cylindrical body. The cylindrical body has a distal end and a proximal end and defines a throughbore. The cap-bladder assembly is adapted for connection to the distal end of the cylindrical body, and includes a cap body and a bladder. The cap body defines an interior cavity and a distal discharge conduit and is adapted to engage the distal end of the cylindrical body. A disc-shaped bladder is disposed within the interior cavity and typically includes a central membrane portion. The plunger element is disposed in the throughbore of the cylindrical body and is vented to enable evacuation of the space between the plunger element and the cap-bladder assembly in the cylindrical body.
摘要翻译：用于流体输送系统的膀胱注射器包括圆柱体，囊 - 囊组件，设置在圆柱体中的柱塞元件和用于将囊 - 囊组件固定到圆柱体上的安装组件。圆柱体具有远端和近端并限定通孔。盖囊组件适于连接到圆柱体的远端，并且包括帽体和囊。盖体限定内腔和远端排出导管，并适于接合圆柱体的远端。盘状囊体设置在内腔内，通常包括中央膜部分。柱塞元件设置在圆柱形主体的通孔中并且被排气以便能够排出柱塞元件和圆柱体中的囊 - 囊组件之间的空间。

9. 再颁专利

USRE42611E1 Continuous battery charger system 有权
标题翻译：连续电池充电系统
公开(公告)号：USRE42611E1
公开(公告)日：2011-08-16
申请号：US12116505
申请日：2008-05-07
申请人： Edward P. Liscio , John A. Brosovich , Richard A. Riggio , Mark Trocki
发明人： Edward P. Liscio , John A. Brosovich , Richard A. Riggio , Mark Trocki
IPC分类号： H01M10/46 , H02J7/00
CPC分类号： H02J7/0068 , A61B5/0046 , A61M5/007 , A61M5/14546 , A61M2205/8206 , A61M2205/8237 , H02J7/045
摘要： A battery charger system, for use with an injector system, comprises a power supply and a battery pack. The power supply converts AC power to DC power. The battery pack includes a battery and a charging module. The module monitors the operating mode of the injector system. When the battery pack is disconnected from the injection control unit, the module enables the power supply to charge the battery with DC power. When the battery pack is connected to the injection control unit: (A) upon detecting the injector system in an idle mode, the module routes DC power from the power supply to both the battery for charging thereof and the injection control unit for operation thereof; and (B) upon detecting the injector system in a non-idle mode, the module prevents the power supply from charging the battery and enables the battery to provide DC power to the injection control unit.
摘要翻译：与注射器系统一起使用的电池充电器系统包括电源和电池组。电源将交流电转换成直流电源。电池组包括电池和充电模块。模块监控喷油器系统的运行模式。当电池组与注射控制单元断开连接时，该模块可使电源以直流电为电池充电。当电池组连接到喷射控制单元时：（A）在空气模式下检测到喷射器系统时，该模块将来自电源的DC电力传送到用于充电的电池和用于操作的注射控制单元; 和（B）当在非空闲模式下检测到喷射器系统时，该模块防止电源对电池充电并使电池能够向喷射控制单元提供直流电力。

10. 发明申请

US20110028908A1 SYSTEM FOR PROCESSING CELLS AND CONTAINER FOR USE THEREWITH 有权
标题翻译：用于处理细胞和容器的系统用于其中
公开(公告)号：US20110028908A1
公开(公告)日：2011-02-03
申请号：US12732250
申请日：2010-03-26
申请人： Arthur E. Uber, III , Mark Trocki , Frederick W. Trombley, III , Kevin P. Cowan
发明人： Arthur E. Uber, III , Mark Trocki , Frederick W. Trombley, III , Kevin P. Cowan
IPC分类号： A61M5/31 , A61J1/00
CPC分类号： A61J1/1443 , A61J1/1456 , A61J1/1475 , A61M5/142 , A61M5/1723 , A61M5/3145 , A61M31/005 , B01L3/502 , B01L2300/044 , B01L2300/0681 , G06F19/3468
摘要： A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.
摘要翻译：用于处理细胞（和/或其它注射组分）的系统包括适于可滑动地定位在容器内的容器和柱塞。该系统包括至少一个入口，流体可以通过该入口进入系统和至少一个流出物端口，流出物可通过该至少一个出口端口离开系统。柱塞部分形成与容器的内壁的密封接合，使得柱塞的向后运动适于经由入口将流体引入系统，并且柱塞的向前运动适于通过流出物强制流出系统的流出物港口。

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