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1. 发明申请

US20110296553A1 ENGINEERING BROAD AND DURABLE RESISTANCE TO GRAPEVINE FANLEAF VIRUS IN PLANTS 有权
标题翻译：工程广泛和耐久耐受的植物花粉病毒
公开(公告)号：US20110296553A1
公开(公告)日：2011-12-01
申请号：US13126956
申请日：2009-11-02
申请人： Marc Fuchs , Jonathan Oliver
发明人： Marc Fuchs , Jonathan Oliver
IPC分类号： C12N15/82 , C07H21/02 , C12N15/63 , C12N5/10 , C12G1/02 , A01H5/00 , A01H5/06 , A23L1/212 , A23L2/02 , C07H21/04 , C12N1/21
CPC分类号： C12N15/8283 , C07K14/005 , C12N2770/32022
摘要： The present invention relates to nucleic acid molecules useful for conferring broad and durable resistance to grapevine fanleaf virus in plants. The invention also relates to methods of enhancing resistance to plant pathogens and plants or plant components (such as grape plants) expressing such nucleic acid molecules. In addition, the invention relates to products (e.g., foodstuffs including beverages such as wine or juice) derived from grape plants transformed with such nucleic acids.
摘要翻译：本发明涉及可用于在植物中赋予葡萄叶扇叶病毒广泛耐久性的核酸分子。本发明还涉及增强对植物病原体的抗性和表达这种核酸分子的植物或植物成分（如葡萄植物）的方法。此外，本发明涉及从用这种核酸转化的葡萄植物得到的产品（例如，包括饮料如葡萄酒或果汁的食品）。

2. 发明授权

US06667426B1 Grapevine fanleaf virus resistance in grapevine expressing grapevine fanleaf virus coat protein 失效
标题翻译：葡萄叶扇叶病毒外壳蛋白中葡萄叶扇叶病毒抗性
公开(公告)号：US06667426B1
公开(公告)日：2003-12-23
申请号：US09162017
申请日：1998-09-28
申请人： Dennis Gonsalves , Baodi Xue , Tania Krastanova , Kai-Shu Ling , Marc Fuchs
发明人： Dennis Gonsalves , Baodi Xue , Tania Krastanova , Kai-Shu Ling , Marc Fuchs
IPC分类号： C12N504
CPC分类号： C07K14/005 , A01H1/04 , A01H5/08 , A01H6/88 , C12N15/8205 , C12N15/8283 , C12N2770/00022 , C12N2770/32022
摘要： In general, the invention features a method for selecting a transgenic grapevine or grapevine component having increased resistance to a fanleaf disease, the method including the steps of: (a) transforming a grape plant cell with a grape nepovirus coat protein nucleic acid molecule or fragment thereof which is capable of being expressed in the plant cell; (b) regenerating a transgenic grapevine or grapevine component from the plant cell; and (c) selecting a transgenic grapevine or grapevine component which expresses, at a low level, the nucleic acid molecule or fragment thereof, wherein the low level expression increases the resistance of the transgenic grapevine or grapevine component to fanleaf disease. The invention also relates to an isolated nucleic acid molecule encoding a coat protein or fragment thereof of a ‘Geneva’ isolate of a grapevine nepovirus virus.
摘要翻译：通常，本发明的特征在于一种选择具有增加的扇叶病抗性的转基因葡萄树或葡萄树成分的方法，所述方法包括以下步骤：（a）用葡萄树突状病毒外壳蛋白核酸分子或片段转化葡萄植物细胞其能够在植物细胞中表达; （b）从植物细胞再生转基因葡萄或葡萄成分; 和（c）选择在低水平表达核酸分子或其片段的转基因葡萄或葡萄成分，其中低水平表达增加转基因葡萄或葡萄成分对扇叶病的抗性。本发明还涉及编码葡萄树病毒病毒的“日内瓦”分离物的外壳蛋白或其片段的分离的核酸分子。

3. 发明授权

US08669419B2 Engineering broad and durable resistance to grapevine fanleaf virus in plants 有权
标题翻译：在植物中对葡萄叶扇病毒进行广泛耐用的抗性
公开(公告)号：US08669419B2
公开(公告)日：2014-03-11
申请号：US13126956
申请日：2009-11-02
申请人： Marc Fuchs , Jonathan Oliver
发明人： Marc Fuchs , Jonathan Oliver
IPC分类号： C07H21/04 , C07H21/02 , C12N15/79
CPC分类号： C12N15/8283 , C07K14/005 , C12N2770/32022
摘要： The present invention relates to nucleic acid molecules useful for conferring broad and durable resistance to grapevine fanleaf virus in plants. The invention also relates to methods of enhancing resistance to plant pathogens and plants or plant components (such as grape plants) expressing such nucleic acid molecules. In addition, the invention relates to products (e.g., foodstuffs including beverages such as wine or juice) derived from grape plants transformed with such nucleic acids.
摘要翻译：本发明涉及可用于在植物中赋予葡萄叶扇叶病毒广泛耐久性的核酸分子。本发明还涉及增强对植物病原体的抗性和表达这种核酸分子的植物或植物成分（如葡萄植物）的方法。此外，本发明涉及从用这种核酸转化的葡萄植物得到的产品（例如，包括饮料如葡萄酒或果汁的食品）。

4. 发明授权

US07211710B2 Grapevine fanleaf virus resistance in grapevine 有权
标题翻译：葡萄柚叶病毒抗性
公开(公告)号：US07211710B2
公开(公告)日：2007-05-01
申请号：US10377435
申请日：2003-02-28
申请人： Dennis Gonsalves , Baodi Xue , Tania Krastanova , Kai-Shu Ling , Marc Fuchs
发明人： Dennis Gonsalves , Baodi Xue , Tania Krastanova , Kai-Shu Ling , Marc Fuchs
IPC分类号： C12N15/82 , C12N15/90
CPC分类号： C07K14/005 , A01H1/04 , A01H5/08 , A01H6/88 , C12N15/8205 , C12N15/8283 , C12N2770/00022 , C12N2770/32022
摘要： In general, the invention features a method for selecting a transgenic grapevine or grapevine component having increased resistance to a grapevine fanleaf disease. The method involves (a) transforming a grape plant cell with a grapevine fanleaf virus coat protein nucleic acid molecule or fragment thereof which is expressed in the plant cell; (b) regenerating a transgenic grapevine or grapevine component from the plant cell; and (c) selecting a transgenic grapevine or grapevine component expressing a grapevine fanleaf virus coat protein or coat protein fragment thereof, where the coat protein or the coat protein fragment thereof is expressed at a level equal to or less than an optical density of about 0.2 at 405 nm as detected by an enzyme-linked immunoassay as compared to a control plant, the selected transgenic grapevine or grapevine component having resistance to the grapevine fanleaf disease.
摘要翻译：通常，本发明的特征在于选择具有增加的对葡萄叶扇叶病抗性的转基因葡萄树或葡萄树成分的方法。该方法包括：（a）在植物细胞中表达的葡萄籽叶病毒外壳蛋白核酸分子或其片段转化葡萄植物细胞; （b）从植物细胞再生转基因葡萄或葡萄成分; 和（c）选择表达葡萄叶扇叶病毒外壳蛋白或外壳蛋白片段的转基因葡萄或葡萄成分，其中外壳蛋白或其外壳蛋白片段以等于或小于约0.2的光密度的水平表达在与对照植物相比通过酶联免疫测定法检测的405nm处，所选择的转基因葡萄树或葡萄树成分具有对葡萄叶扇叶病的抗性。

5. 发明申请

US20050022384A1 Method for producing die-cast parts and a die casting device 审中-公开
标题翻译：压铸件的制造方法和压铸装置
公开(公告)号：US20050022384A1
公开(公告)日：2005-02-03
申请号：US10495680
申请日：2002-11-26
申请人： Benno Niedermann , Roberto Bologna , Marc Fuchs
发明人： Benno Niedermann , Roberto Bologna , Marc Fuchs
IPC分类号： B22D15/00 , B22D17/00 , B21K1/38
CPC分类号： B22D17/007 , B22D15/005 , Y10T29/49524 , Y10T29/49988
摘要： The invention relates to a method for producing die-cast parts, in particular wheel rims or wheels for vehicles, in addition to a diecasting device therefor. To produce high quality wheel rims or wheels, the starting materials are heated in stages in a casting cell and are transferred in a semi-solid form to a die casting machine, where they are formed into die-cast parts.
摘要翻译：本发明涉及一种用于生产压铸件，特别是用于车辆的车轮轮缘或车轮的方法，以及其压铸装置。为了生产高品质的轮缘或车轮，起始材料在铸造槽中分阶段加热，并以半固体形式转移到压铸机上，在那里形成压铸件。

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