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1. 发明授权

US09433533B2 Patch package structure 有权
标题翻译：贴片包装结构
公开(公告)号：US09433533B2
公开(公告)日：2016-09-06
申请号：US11972910
申请日：2008-01-11
申请人： Katsuhiro Okada , Yoshihiro Iwao , Kensuke Matsuoka
发明人： Katsuhiro Okada , Yoshihiro Iwao , Kensuke Matsuoka
IPC分类号： A61M35/00 , A61F13/02 , A61F13/551 , A61F15/00 , A61F13/00 , A61B17/06
CPC分类号： A61F13/0203 , A61F13/551 , A61F15/001
摘要： The present invention provides a patch package structure, which includes: a package including a first sheet material which is planar and a second sheet material which has been molded, the first and second sheet materials being sealed together in peripheral parts thereof, and a patch disposed in the package, in which the patch contains a backing, a pressure-sensitive adhesive layer laminated on at least one side of the backing, and a release liner which protects a pressure-sensitive adhesive surface of the pressure-sensitive adhesive layer; the second sheet material has been molded so as to have a protrudent part in at least a substantially central area thereof, the protrudent part having a planar outer shape larger than a planar outer shape of the release liner and having at least one recessed part; d is not smaller than T, in which d is the minimum gap distance between the inner surface of the first sheet material and the inner surface of the second sheet material at the recessed part and T is a thickness of the patch; and, at the boundary between the sealed part where the first and second sheet materials are sealed together and an unsealed part, the outer surface of the second sheet material rises at an obtuse angle.
摘要翻译：本发明提供了一种贴片包装结构，其包括：包括平面的第一片材和已经模制的第二片材的封装，第一和第二片材在其周边部分被密封在一起，并且贴片布置在其中贴片包含背衬的包装中，层压在背衬的至少一侧上的压敏粘合剂层和保护压敏粘合剂层的压敏粘合剂表面的剥离衬垫; 第二片材已经被模制成在其至少大致中心区域具有突出部分，突出部分具有比剥离衬垫的平面外形大的平面外形，并且具有至少一个凹部; d不小于T，其中d是第一片材的内表面和凹陷部分的第二片材的内表面之间的最小间隙距离，T是贴片的厚度; 并且在第一和第二片材密封在一起的密封部分与未密封部分之间的边界处，第二片材的外表面以钝角上升。

2. 发明授权

US09351942B2 Patch and patch preparation 有权
标题翻译：补丁和补丁准备
公开(公告)号：US09351942B2
公开(公告)日：2016-05-31
申请号：US13983481
申请日：2012-02-01
申请人： Masato Nishimura , Yoshihiro Iwao , Katsuhiro Okada , Kensuke Matsuoka
发明人： Masato Nishimura , Yoshihiro Iwao , Katsuhiro Okada , Kensuke Matsuoka
IPC分类号： A61K9/70 , A61K31/405 , A61K31/663
CPC分类号： A61K9/7053 , A61K31/405 , A61K31/663 , Y10T428/2857
摘要： The invention provides a patch and a patch preparation having an adhesive layer with a high adhesive force, wherein the hydrophobic adhesive layer does not bloom even when an organic fluid component having high polarity is contained therein. The patch contains a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a synthetic rubber having a viscosity average molecular weight of 1,700,000-6,500,000, an organic fluid component having high polarity, a tackifier, and magnesium aluminometasilicate. In the patch preparation, the above-mentioned adhesive layer further contains a drug.
摘要翻译：本发明提供了具有粘合力高的贴剂和贴片制剂，其中即使含有高极性的有机流体组分，疏水性粘合剂层也不会起泡。该贴片在支撑体的至少一个表面上包含支撑体和粘合剂层，其中粘合剂层含有粘均分子量为170万至6,500,000的合成橡胶，具有高极性的有机流体组分，增粘剂和镁硅酸铝在贴片制剂中，上述粘合剂层还含有药物。

3. 发明申请

US20130315978A1 PATCH AND PATCH PREPARATION 有权
标题翻译：配对和配对准备
公开(公告)号：US20130315978A1
公开(公告)日：2013-11-28
申请号：US13983481
申请日：2012-02-01
申请人： Masato Nishimura , Yoshihiro Iwao , Katsuhiro Okada , Kensuke Matsuoka
发明人： Masato Nishimura , Yoshihiro Iwao , Katsuhiro Okada , Kensuke Matsuoka
IPC分类号： A61K9/70 , A61K31/663 , A61K31/405
CPC分类号： A61K9/7053 , A61K31/405 , A61K31/663 , Y10T428/2857
摘要： The invention provides a patch and a patch preparation having an adhesive layer with a high adhesive force, wherein the hydrophobic adhesive layer does not bloom even when an organic fluid component having high polarity is contained therein. The patch contains a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a synthetic rubber having a viscosity average molecular weight of 1,700,000-6,500,000, an organic fluid component having high polarity, a tackifier, and magnesium aluminometasilicate. In the patch preparation, the above-mentioned adhesive layer further contains a drug.
摘要翻译：本发明提供了具有粘合力高的贴剂和贴片制剂，其中即使含有高极性的有机流体组分，疏水性粘合剂层也不会起泡。该贴片在支撑体的至少一个表面上包含支撑体和粘合剂层，其中粘合剂层含有粘均分子量为170万至6,500,000的合成橡胶，具有高极性的有机流体组分，增粘剂和镁硅酸铝在贴片制剂中，上述粘合剂层还含有药物。

4. 发明申请

US20130315976A1 PATCH PREPARATION 有权
标题翻译：配对准备
公开(公告)号：US20130315976A1
公开(公告)日：2013-11-28
申请号：US13983134
申请日：2012-02-01
申请人： Yasuaki Okada , Katsuhiro Okada , Masato Nishimura , Yuji Kawaharada
发明人： Yasuaki Okada , Katsuhiro Okada , Masato Nishimura , Yuji Kawaharada
IPC分类号： A61K9/70
CPC分类号： A61K9/7038 , A61K9/7061 , A61K31/167 , A61K31/4453 , A61K31/496
摘要： The problem of the present invention is to provide a patch preparation containing a drug (excluding 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine and a physiologically acceptable acid addition salt thereof), which is superior in both the skin permeability of a drug, and adhesiveness in the presence of water.A patch preparation containing a support and an adhesive layer on one surface of the support, wherein the adhesive layer contains a drug excluding 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine and a physiologically acceptable acid addition salt thereof, an acrylic polymer, lactic acid and magnesium aluminometasilicate.
摘要翻译：本发明的问题在于提供含有药物（不含2-（4-乙基-1-哌嗪基）-4-（4-氟苯基）-5,6,7,8,9,10-六氢环辛酸 [b]吡啶及其生理上可接受的酸加成盐），其在药物的皮肤渗透性方面都优异，并且在水存在下的粘合性。在载体的一个表面上含有载体和粘合剂层的贴片制剂，其中所述粘合剂层含有除2-（4-乙基-1-哌嗪基）-4-（4-氟苯基）-5,6,7 ，8,9,10-六氢环辛基[b]吡啶及其生理上可接受的酸加成盐，丙烯酸聚合物，乳酸和硅酸铝镁。

5. 发明申请

US20130310777A1 PATCH AND PATCH PREPARATION 有权
标题翻译：配对和配对准备
公开(公告)号：US20130310777A1
公开(公告)日：2013-11-21
申请号：US13983510
申请日：2012-02-01
申请人： Masato Nishimura , Yoshihiro Iwao , Katsuhiro Okada , Kensuke Matsuoka
发明人： Masato Nishimura , Yoshihiro Iwao , Katsuhiro Okada , Kensuke Matsuoka
IPC分类号： A61M35/00 , A61L31/12
CPC分类号： A61M35/00 , A61K9/7053 , A61K31/405 , A61K31/663 , A61L31/129
摘要： The invention provides a patch and a patch preparation having an adhesive layer with a high adhesive force, wherein the hydrophobic adhesive layer does not bloom even when an organic fluid component having high polarity is contained therein. The patch contains a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a synthetic rubber having a viscosity average molecular weight of 500,000-1,600,000, an organic fluid component having high polarity, a tackifier, and magnesium aluminometasilicate. In the patch preparation, the above-mentioned adhesive layer further contains a drug.
摘要翻译：本发明提供了具有粘合力高的贴剂和贴片制剂，其中即使含有高极性的有机流体组分，疏水性粘合剂层也不会起泡。该贴片在支撑体的至少一个表面上包含支撑体和粘合剂层，其中粘合剂层含有粘均分子量为500,000-1,600,000的合成橡胶，具有高极性的有机流体组分，增粘剂和镁硅酸铝在贴片制剂中，上述粘合剂层还含有药物。

6. 发明授权

US08127926B2 Patch package structure 有权
标题翻译：贴片包装结构
公开(公告)号：US08127926B2
公开(公告)日：2012-03-06
申请号：US12644160
申请日：2009-12-22
申请人： Katsuhiro Okada , Yoshihiro Iwao , Kensuke Matsuoka
发明人： Katsuhiro Okada , Yoshihiro Iwao , Kensuke Matsuoka
IPC分类号： A61L15/16
CPC分类号： A61F15/001 , A61F13/551 , A61F2013/00897
摘要： A patch package structure which includes: a package including a first sheet material which is planar and a second sheet material which has been molded, a peripheral area of the first sheet material having been sealed to a peripheral area of the second sheet material to constitute the package, and a patch disposed in the package; in which the patch includes a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner which protects the pressure-sensitive adhesive surface of the pressure-sensitive adhesive layer, the release liner having a weakening line for assisting a removal of the release liner; and in which the second sheet material has specific first protrudent part, second protrudent part, third protrudent part and elevated part in a central area thereof except the peripheral area thereof.
摘要翻译：一种贴片包装结构，包括：包括平面的第一片材和已经模制的第二片材的封装，第一片材的周边区域被密封到第二片材的周边区域，以构成第包装和贴在包装中的贴片; 其中所述贴剂包括背衬，形成在所述背衬的至少一侧上的压敏粘合剂层和保护所述压敏粘合剂层的压敏粘合剂表面的剥离衬垫，所述剥离衬垫具有弱化用于帮助去除脱模衬垫的管线; 并且其中所述第二片材在其外围区域的中心区域中具有特定的第一突出部分，第二突出部分，第三突出部分和升高部分。

7. 发明申请

US20110134383A1 ACTIVE MATRIX SUBSTRATE, DISPLAY PANEL, AND DISPLAY APPARATUS 审中-公开
标题翻译：主动矩阵基板，显示面板和显示设备
公开(公告)号：US20110134383A1
公开(公告)日：2011-06-09
申请号：US13058645
申请日：2009-05-22
申请人： Katsuhiro Okada , Hitoshi Matsumoto
发明人： Katsuhiro Okada , Hitoshi Matsumoto
IPC分类号： G02F1/1343
CPC分类号： G02F1/134336 , G02F1/134363 , G02F2001/133388
摘要： An active matrix substrate (3) of the present invention includes: a plurality of pixels (5) which constitute a display region (4); and a plurality of dummy pixels (6, 8, 10, 12) which are provided around the display region (4), each of the plurality of pixels (5) having a diagonal pattern (14) of a plurality of diagonal lines each of which has a constant width, at least one of the plurality of dummy pixels (6, 8, 10, 12) having at least one measuring pattern of a plurality of vertical or horizontal lines each of which has the constant width. This allows measurement of a line width of a pattern and alignment correction, without increasing a picture-frame region of the active matrix substrate (3).
摘要翻译：本发明的有源矩阵基板（3）包括：构成显示区域（4）的多个像素（5）; 以及设置在所述显示区域（4）周围的多个虚拟像素（6,8,10,12），所述多个像素（5）中的每一个具有多个对角线的对角线图案（14），每个对角线其具有恒定的宽度，所述多个虚拟像素（6,8,10,12）中的至少一个具有至少一个具有恒定宽度的多个垂直或水平线的测量图案。这允许测量图案的线宽和对准校正，而不增加有源矩阵衬底（3）的图像帧区域。

8. 发明申请

US20110075087A1 LIQUID CRYSTAL DISPLAY DEVICE 有权
标题翻译：液晶显示装置
公开(公告)号：US20110075087A1
公开(公告)日：2011-03-31
申请号：US12994499
申请日：2009-03-27
申请人： Junichi Morinaga , Katsushige Asada , Masahiro Yoshida , Tetsuya Fujikawa , Katsuhiro Mikumo , Kuniko Maeno , Ryohki Itoh , Satoshi Horiuchi , Tatsuji Saitoh , Isao Ogasawara , Kazunori Tanimoto , Katsuhiro Okada , Toshiaki Fujihara , Masakatsu Tominaga
发明人： Junichi Morinaga , Katsushige Asada , Masahiro Yoshida , Tetsuya Fujikawa , Katsuhiro Mikumo , Kuniko Maeno , Ryohki Itoh , Satoshi Horiuchi , Tatsuji Saitoh , Isao Ogasawara , Kazunori Tanimoto , Katsuhiro Okada , Toshiaki Fujihara , Masakatsu Tominaga
IPC分类号： G02F1/1343
CPC分类号： G02F1/136286 , G02F1/133707 , G02F1/134309 , G02F1/1393
摘要： Each of picture elements (14) has a plurality of alignment regions (R1, R2, R3, and R4), in each of which liquid crystal molecules contained in a liquid crystal layer are aligned in a direction that is different from those in the others of the plurality of alignment regions. Each of a plurality of scanning signal lines (32) and a border region (R11 and R12) between corresponding adjacent ones of the plurality of alignment regions (R1, R2, R3, and R4) at least partially overlap each other when viewed from above.
摘要翻译：每个像素（14）具有多个取向区域（R1，R2，R3和R4），其中液晶层中所含的液晶分子在与其它方向不同的方向上排列的多个对准区域。当从上方观察时，多个对准区域（R1，R2，R3和R4）中相应的相邻的对齐区域（R1，R2，R3和R4）之间的多个扫描信号线（32）和边界区域（R11和R12）中的每一个至少部分地彼此重叠。

9. 发明申请

US20100158991A1 PATCH PACKAGE STRUCTURE 有权
标题翻译： PATCH包装结构
公开(公告)号：US20100158991A1
公开(公告)日：2010-06-24
申请号：US12644160
申请日：2009-12-22
申请人： Katsuhiro OKADA , Yoshihiro IWAO , Kensuke MATSUOKA
发明人： Katsuhiro OKADA , Yoshihiro IWAO , Kensuke MATSUOKA
IPC分类号： A61K9/00 , B32B37/02 , A61P43/00 , B65D85/16 , A61M35/00
CPC分类号： A61F15/001 , A61F13/551 , A61F2013/00897
摘要： A patch package structure which includes: a package including a first sheet material which is planar and a second sheet material which has been molded, a peripheral area of the first sheet material having been sealed to a peripheral area of the second sheet material to constitute the package, and a patch disposed in the package; in which the patch includes a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner which protects the pressure-sensitive adhesive surface of the pressure-sensitive adhesive layer, the release liner having a weakening line for assisting a removal of the release liner; and in which the second sheet material has specific first protrudent part, second protrudent part, third protrudent part and elevated part in a central area thereof except the peripheral area thereof.
摘要翻译：一种贴片包装结构，包括：包括平面的第一片材和已经模制的第二片材的封装，第一片材的周边区域被密封到第二片材的周边区域，以构成第包装和贴在包装中的贴片; 其中所述贴剂包括背衬，形成在所述背衬的至少一侧上的压敏粘合剂层和保护所述压敏粘合剂层的压敏粘合剂表面的剥离衬垫，所述剥离衬垫具有弱化用于帮助去除脱模衬垫的管线; 并且其中所述第二片材在其外围区域的中心区域中具有特定的第一突出部分，第二突出部分，第三突出部分和升高部分。

10. 发明申请

US20090169604A1 Adhesive Pharmaceutical Preparation Containing Bisoprolol 有权
标题翻译：含有比索洛尔的胶粘剂药物制剂
公开(公告)号：US20090169604A1
公开(公告)日：2009-07-02
申请号：US12097260
申请日：2006-12-13
申请人： Yoshihiro Iwao , Katsuyuki Ookubo , Katsuhiro Okada , Kunihiro Minami , Shuichiro Yuasa
发明人： Yoshihiro Iwao , Katsuyuki Ookubo , Katsuhiro Okada , Kunihiro Minami , Shuichiro Yuasa
IPC分类号： A61K9/70 , A61K31/135 , A61P9/00
CPC分类号： A61K9/7053 , A61K31/138 , A61K47/10 , A61K47/32
摘要： In the adhesive pharmaceutical preparation of the invention containing bisoprolol, a pressure-sensitive adhesive layer is laminated on one side of the backing. The pressure-sensitive adhesive layer contains a branched monoalcohol having from 12 to 28 carbon atoms, a free base of bisoprolol and a polyisobutylene pressure-sensitive adhesive. Accordingly, compatibility of the polyisobutylene pressure-sensitive adhesive with the free base of bisoprolol can be specifically increased. As a result, not only it becomes possible to increase blending amount of the free base of bisoprolol but also bleed of the free base of bisoprolol from the pressure-sensitive adhesive layer can be suppressed and, what is more, the pressure-sensitive adhesion characteristics sufficient from the practical point of view can be obtained.
摘要翻译：在含有比索洛尔的本发明的粘合剂药物制剂中，在背衬的一侧层压压敏粘合剂层。压敏粘合剂层含有具有12至28个碳原子的支链一元醇，比索洛尔的游离碱和聚异丁烯压敏粘合剂。因此，可以特异性地增加聚异丁烯压敏粘合剂与比索洛尔的游离碱的相容性。结果，可以抑制比索洛尔的游离碱的混合量的增加，而且可以抑制比索洛尔的游离碱从压敏粘合剂层的渗出，而且还可以抑制压敏粘合特性从实用的角度来看可以获得足够的。

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