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1. 发明授权

US07060092B2 Deployable stent 失效
标题翻译：可部署支架
公开(公告)号：US07060092B2
公开(公告)日：2006-06-13
申请号：US10473232
申请日：2002-03-27
申请人： Kaori Kuribayashi , Zhong You
发明人： Kaori Kuribayashi , Zhong You
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2/07 , A61F2/844 , A61F2/90 , A61F2210/0076 , A61F2230/005
摘要： A stent 1 comprising a sheet 2 of biocompatible material arranged as a tube and having a pattern of folds allowing the stent to be collapsed for deployment. The pattern of folds comprises a unit cell repeated over the sheet 2. A variety of different unit cells 3 are described. The pattern of folds may progress helically around the tube which assists in implantation by synchronising deployment. The stent 1 prevents restenosis because it is formed of a continuous sheet 2, and allows slippage to be minimised.
摘要翻译：一种支架1，其包括布置成管的生物相容性材料的片材2，并且具有允许支架折叠以展开的折叠图案。折叠图案包括在片材2上重复的单元电池。描述了各种不同的单元电池3。折叠的图案可以在管周围螺旋地进行，这有助于通过同步部署来植入。支架1防止再狭窄，因为它由连续的片材2形成，并允许滑动最小化。

2. 发明授权

US08999443B2 Method for fabricating a microarray of soft materials 有权
标题翻译：软材料微阵列的制造方法
公开(公告)号：US08999443B2
公开(公告)日：2015-04-07
申请号：US13814588
申请日：2012-03-27
申请人： Satoshi Hiyama , Kaori Kuribayashi , Hiroaki Onoe , Shoji Takeuchi
发明人： Satoshi Hiyama , Kaori Kuribayashi , Hiroaki Onoe , Shoji Takeuchi
IPC分类号： C23C16/00 , B05D1/32 , C12N15/09 , G01N37/00 , G01N33/543 , B81C1/00
CPC分类号： B05D1/325 , B01J2219/00317 , B01J2219/00529 , B01J2219/00637 , B01J2219/00659 , B01J2219/00722 , B01J2219/00725 , B81B2201/0214 , B81B2201/058 , B81C1/00206 , C12N15/09 , G01N33/543 , G01N37/00
摘要： A method for fabricating a microarray of plural soft materials includes: vapor-depositing a first layer poly(para-xylylene) resin on a substrate, forming a first micro pattern in the poly(para-xylylene) resin; obtaining a substrate including a first microarray formed by pouring a first soft material solution, freeze-drying the first soft material to obtain a micro-arrayed substrate of the freeze-dried first soft material; vapor-depositing a second layer poly(para-xylylene) resin on the micro-arrayed substrate of the freeze-dried first soft material, forming a second micro pattern placed differently from the first micro pattern by penetrating the poly(para-xylylene) resin of the first and second layers, forming a second microarray on the substrate by pouring a second soft material solution; and forming a microarray of the first and second soft materials on the substrate by peeling off the poly(para-xylylene) resin of the first and second layers.
摘要翻译：一种制备多种软材料的微阵列的方法包括：在基材上蒸镀第一层聚（对二甲苯）树脂，在聚（对二甲苯）树脂中形成第一微图案; 获得包括通过倾倒第一软质材料溶液形成的第一微阵列的基板，冷冻干燥第一软质材料以获得冷冻干燥的第一软质材料的微阵列基板; 在冷冻干燥的第一软质材料的微阵列基底上气相沉积第二层聚（对二甲苯）树脂，通过穿透聚（对二甲苯）树脂形成不同于第一微图案的第二微图案的第一和第二层，通过倾倒第二软材料溶液在基底上形成第二微阵列; 以及通过剥离第一层和第二层的聚（对二甲苯）树脂，在基材上形成第一和第二软材料的微阵列。

3. 发明申请

US20060252624A1 Deployable stent 审中-公开
标题翻译：可部署支架
公开(公告)号：US20060252624A1
公开(公告)日：2006-11-09
申请号：US11410299
申请日：2006-04-25
申请人： Kaori Kuribayashi , Zhong You
发明人： Kaori Kuribayashi , Zhong You
IPC分类号： B31B3/00
CPC分类号： A61F2/82 , A61F2/07 , A61F2/844 , A61F2/90 , A61F2210/0076 , A61F2230/005
摘要： A stent 1 comprises a sheet 2 of biocompatible material having a tubular shape and folded with a pattern of folds allowing the sheet 2 to be collapsed for deployment. The pattern of folds comprises a unit cell repeated over the sheet 2. A variety of different unit cells 3 are described. The pattern of folds may progress helically around the tubular shape of the sheet 2 which assists in implantation by synchronising deployment. The stent 1 further comprises a frame extending around the tubular shape of the sheet 2 and reinforcing the sheet 2. The frame comprises a plurality of elongate members arranged to fold relative to each other in conformity with the sheet 2 to allow the frame to be collapsed with the sheet 2 for deployment of the stent 1. The stent 1 prevents tissue in-growth because it is formed of a continuous sheet 2.
摘要翻译：支架1包括具有管状形状的生物相容性材料片2，并折叠成允许片材2折叠以展开的折叠图案。折叠图案包括在片材2上重复的单元电池。描述了各种不同的单元电池3。折叠图案可以围绕片材2的管状形状螺旋形地进行，这有助于通过同步展开进行植入。支架1还包括围绕片材2的管状形状延伸并且增强片材2的框架。框架包括多个细长构件，其布置成与片材2一致地相对于彼此折叠，以允许框架与用于展开支架1的片材2折叠。支架1防止组织生长，因为它由连续片材2形成。

4. 发明申请

US20100307918A1 METHOD OF PREPARING ARTIFICIAL LIPID MEMBRANES OVER MICROAPERTURES OF SUBSTRATE AND SUBSTRATE FOR HOLDING ARTIFICIAL LIPID MEMBRANES 审中-公开
标题翻译：用于保存人造脂膜的底物和底物的微孔中制备人造脂膜的方法
公开(公告)号：US20100307918A1
公开(公告)日：2010-12-09
申请号：US12745317
申请日：2008-10-28
申请人： Shoji Takeuchi , Kaori Kuribayashi
发明人： Shoji Takeuchi , Kaori Kuribayashi
IPC分类号： C25D1/12 , C25D17/06
CPC分类号： G01N33/48728 , A61K9/1277
摘要： There is provided a method of preparing organic-solvent-free artificial lipid membranes formed over microapertures of a substrate and a substrate for holding the artificial lipid membranes. The method of preparing artificial lipid membranes over microapertures of a substrate includes forming a lipid pattern 5 on the perimeter of microapertures 4 formed in a substrate 1, swelling the lipid pattern 5 by an electroformation method, fusing the swelled lipid pattern, and further swelling the fused lipid pattern for each microaperture to prepare dome-shaped organic-solvent-free lipid membranes 7.
摘要翻译：提供了一种制备在基材和用于保持人造脂膜的底物的微孔下形成的不含有机溶剂的人造脂膜的方法。在底物的微孔上制备人造脂质膜的方法包括在形成于底物1中的微孔4的周边上形成脂质图案5，通过电化学方法使脂质图案5膨胀，使溶胀的脂质图案融化，并进一步溶胀每个微孔的融合脂质图案制备圆顶状有机溶剂脂质膜7。

5. 发明申请

US20130136863A1 METHOD FOR FABRICATING A MICROARRAY OF SOFT MATERIALS 有权
标题翻译：微软材料制作方法
公开(公告)号：US20130136863A1
公开(公告)日：2013-05-30
申请号：US13814588
申请日：2012-03-27
申请人： Satoshi Hiyama , Kaori Kuribayashi , Hiroaki Onoe , Shoji Takeuchi
发明人： Satoshi Hiyama , Kaori Kuribayashi , Hiroaki Onoe , Shoji Takeuchi
IPC分类号： B05D1/32
CPC分类号： B05D1/325 , B01J2219/00317 , B01J2219/00529 , B01J2219/00637 , B01J2219/00659 , B01J2219/00722 , B01J2219/00725 , B81B2201/0214 , B81B2201/058 , B81C1/00206 , C12N15/09 , G01N33/543 , G01N37/00
摘要： A method for fabricating a microarray of plural soft materials includes: vapor-depositing a first layer poly(para-xylylene) resin on a substrate, forming a first micro pattern in the poly(para-xylylene) resin; obtaining a substrate including a first microarray formed by pouring a first soft material solution, freeze-drying the first soft material to obtain a micro-arrayed substrate of the freeze-dried first soft material; vapor-depositing a second layer poly(para-xylylene) resin on the micro-arrayed substrate of the freeze-dried first soft material, forming a second micro pattern placed differently from the first micro pattern by penetrating the poly(para-xylylene) resin of the first and second layers, forming a second microarray on the substrate by pouring a second soft material solution; and forming a microarray of the first and second soft materials on the substrate by peeling off the poly(para-xylylene) resin of the first and second layers.
摘要翻译：一种制备多种软材料的微阵列的方法包括：在基材上蒸镀第一层聚（对二甲苯）树脂，在聚（对二甲苯）树脂中形成第一微图案; 获得包括通过倾倒第一软质材料溶液形成的第一微阵列的基板，冷冻干燥第一软质材料以获得冷冻干燥的第一软质材料的微阵列基板; 在冷冻干燥的第一软质材料的微阵列基底上气相沉积第二层聚（对二甲苯）树脂，通过穿透聚（对二甲苯）树脂形成不同于第一微图案的第二微图案的第一和第二层，通过倾倒第二软材料溶液在基底上形成第二微阵列; 以及通过剥离第一层和第二层的聚（对二甲苯）树脂，在基材上形成第一和第二软材料的微阵列。

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