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1. 发明申请

US20120028920A1 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS 失效
标题翻译：适用于治疗CNS病症的4-哌啶-1-基-4-苯并[b]噻吩的衍生物
公开(公告)号：US20120028920A1
公开(公告)日：2012-02-02
申请号：US13270544
申请日：2011-10-11
申请人： Hiroshi YAMASHITA , Hideaki Kuroda , Nobuaki Ito , Shin Miyamura , Kunio Oshima , Jun Matsubara , Haruka Takahashi , Tae Fukushima , Satoshi Shimizu , Kazumi Kondo , Yohji Sakurai , Takeshi Kuroda , Shinichi Taira , Motohiro Itotani , Tatsuyoshi Tanaka
发明人： Hiroshi YAMASHITA , Hideaki Kuroda , Nobuaki Ito , Shin Miyamura , Kunio Oshima , Jun Matsubara , Haruka Takahashi , Tae Fukushima , Satoshi Shimizu , Kazumi Kondo , Yohji Sakurai , Takeshi Kuroda , Shinichi Taira , Motohiro Itotani , Tatsuyoshi Tanaka
IPC分类号： A61K31/496 , C07D409/10 , C07D417/14 , C07D413/14 , A61K31/538 , A61K31/517 , A61K31/506 , A61K31/55 , A61K31/5415 , A61K31/553 , C07F7/18 , A61K31/695 , A61P25/18 , A61P25/24 , A61P25/00 , C07D409/14
CPC分类号： C07D409/12 , C07D333/54 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D487/08 , C07D491/113
摘要： A heterocyclic compound or a salt thereof represented by the formula (1): where R2 represents a hydrogen atom or a lower alkyl group; A represents a lower alkylene group or lower alkenylene group; and R1 represents an aromatic group or a heterocyclic group. The compound of the present invention has a wide treatment spectrum for mental disorders including central nervous system disorders, no side effects and high safety.
摘要翻译：由式（1）表示的杂环化合物或其盐：其中R 2表示氢原子或低级烷基; A表示低级亚烷基或低级亚烯基; R1表示芳基或杂环基。本发明的化合物具有广泛的精神障碍治疗范围，包括中枢神经系统疾病，无副作用和高安全性。

2. 发明申请

US20110152286A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS 有权
标题翻译：用于治疗精神疾病的哌嗪取代的苯二酚
公开(公告)号：US20110152286A1
公开(公告)日：2011-06-23
申请号：US12970690
申请日：2010-12-16
申请人： Hiroshi YAMASHITA , Nobuaki Ito , Shin Miyamura , Kunio Oshima , Jun Matsubara , Hideaki Kuroda , Haruka Takahashi , Satoshi Shimizu , Tatsuyoshi Tanaka
发明人： Hiroshi YAMASHITA , Nobuaki Ito , Shin Miyamura , Kunio Oshima , Jun Matsubara , Hideaki Kuroda , Haruka Takahashi , Satoshi Shimizu , Tatsuyoshi Tanaka
IPC分类号： A61K31/497 , C07D401/14 , A61P25/18 , A61P25/24 , A61P25/22 , A61P25/28 , A61P25/14 , A61P25/16
CPC分类号： A61K31/496 , C07D405/12 , C07D409/12 , C07D409/14
摘要： The present invention provides a heterocyclic compound represented by the general formula (1): The compound of the present invention has a wide treatment spectrum for mental disorders including central nervous system disorders, no side effects and high safety.
摘要翻译：本发明提供由通式（1）表示的杂环化合物：本发明化合物具有广泛的精神障碍治疗谱，包括中枢神经系统疾病，副作用高，安全性高。

3. 发明授权

US5857444A Inner cam system distributor type fuel injector 失效
标题翻译：内凸轮系统分配器型燃油喷射器
公开(公告)号：US5857444A
公开(公告)日：1999-01-12
申请号：US919361
申请日：1997-08-28
申请人： Kenichi Kubo , Kazuaki Narikiyo , Jun Matsubara
发明人： Kenichi Kubo , Kazuaki Narikiyo , Jun Matsubara
IPC分类号： F02M41/14 , F02M37/04
CPC分类号： F02M41/1416 , F02M41/1405
摘要： A rotor that rotates in synchronization with an engine is provided inside a housing and a cam ring is provided outside and around the rotor so that plungers are caused to move reciprocally in the direction of the radius by the cam ring as the rotor rotates. At both sides of the cam ring, support members (barrel 8, bearing support member 6) constituted of the same material as that of the cam ring are secured to the housing and to both sides of the cam ring, and these support members alone hold the cam ring from both sides rotatably. A connecting rod connecting the cam ring and the timer mechanism is formed as an integrated part of the cam ring. The clearance between the cam ring and the members holding it can be set small so that the vibration of the cam ring is reduced to minimize the impact noise made by the cam ring and wear of the cam ring. In addition, the connection strength between the cam ring and timer mechanism is increased.
摘要翻译：与发动机同步旋转的转子设置在壳体内部，并且凸轮环设置在转子的外部和周围，使得当转子旋转时，柱塞在半径方向上通过凸轮环往复运动。在凸轮环的两侧，由与凸轮环的材料相同的材料构成的支撑构件（筒8，轴承支撑构件6）固定到壳体和凸轮环的两侧，并且这些支撑构件仅保持凸轮环从两侧可旋转。连接凸轮环和定时器机构的连接杆形成为凸轮环的一体部分。凸轮环与保持其的构件之间的间隙可以设定得较小，使得减小凸轮环的振动以最小化由凸轮环产生的冲击噪声和凸轮环的磨损。此外，凸轮环和定时器机构之间的连接强度增加。

4. 发明授权

US5746584A Inner cam type fuel injection pump having modified plungers 失效
标题翻译：具有改型柱塞的内凸轮式燃油喷射泵
公开(公告)号：US5746584A
公开(公告)日：1998-05-05
申请号：US611670
申请日：1996-03-06
申请人： Hisashi Nakamura , Kenichi Kubo , Jun Matsubara , Kazuaki Narikiyo , Hajime Machida , Noriyuki Abe , Tsunayoshi Motoyoshi , Atsushi Ueda
发明人： Hisashi Nakamura , Kenichi Kubo , Jun Matsubara , Kazuaki Narikiyo , Hajime Machida , Noriyuki Abe , Tsunayoshi Motoyoshi , Atsushi Ueda
IPC分类号： F02M41/14 , F04B19/00
CPC分类号： F02M41/1405
摘要： In an inner cam type injection pump, the side surface of the protruding portion of each of the plungers facing the compression space is formed in a projecting shape in the area where the plunger changes from the base end side into the front end. Specific forms of the projection include a structure constituted with slanted surfaces over a plurality of stages with different inclinations relative to the axis of the plunger, an arc form and a structure provided with a overhanging portion formed on the side surface of the protruding portion, which does not overhang the base end, projecting out from the side surface. This will prevent collision at the shoulder portion of the plunger and, consequently, prevent the deformation at the shoulder portion and ensures that plungers will not have sliding failures or become seized. Even when plungers collide, the sliding of the plungers will not be affected, ensuring that plungers do not have sliding failures or become seized.
摘要翻译：在内凸轮型喷射泵中，每个柱塞的面向压缩空间的突出部分的侧表面在柱塞从基端侧向前端改变的区域中形成为突出形状。突起的具体形式包括由相对于柱塞的轴线具有不同倾斜度的多个台阶上的倾斜表面构成的结构，弧形和设置有形成在突出部分的侧表面上的突出部分的结构，不会从基面突出，从侧面突出。这将防止在柱塞的肩部处的碰撞，从而防止在肩部处的变形，并确保柱塞不会有滑动故障或被抓住。即使柱塞碰撞，柱塞的滑动也不会受到影响，确保柱塞没有滑动故障或被抓住。

5. 发明授权

US5647323A Fuel injection system 失效
标题翻译：燃油喷射系统
公开(公告)号：US5647323A
公开(公告)日：1997-07-15
申请号：US646908
申请日：1996-05-09
申请人： Ken-ichi Kubo , Jun Matsubara , Hiroshi Ishiwata
发明人： Ken-ichi Kubo , Jun Matsubara , Hiroshi Ishiwata
IPC分类号： F02D1/02 , F02D1/04 , F02D1/18 , F02M41/12 , F02M41/14 , F02M41/00
CPC分类号： F02M41/1416 , F02M41/1411
摘要： The movement of a control sleeve in the circumferential direction is made to interlock with the movement of a timer piston to ensure that the control sleeve has a function of pre-stroke control. In order to interlock the movements of the timer piston and the control sleeve, they are linked with first through third link members and the control sleeve is caused to rotate in the circumferential direction at a specific ratio relative to the quantity of movement of the timer piston. In a fuel injection system provided with an actuator for adjusting the fuel force feed end by moving the control sleeve in the direction of the axis and an actuator for controlling the timing with which the cam lift begins, pre-stroke control can be achieved without requiring a separate actuator, with a simple mechanical structure.
摘要翻译：使控制套筒在圆周方向上的移动与定时器活塞的移动互锁，以确保控制套筒具有前冲程控制的功能。为了联锁定时器活塞和控制套筒的运动，它们与第一至第三连杆构件连接，并且控制套筒以相对于定时器活塞的运动量的特定比例在圆周方向上旋转。在具有致动器的燃料喷射系统中，该致动器用于通过沿着该轴线的方向移动控制套筒来调节燃料供给端和用于控制凸轮升程开始的时间的致动器，可以实现前冲程控制，而不需要单独的致动器，具有简单的机械结构。

6. 发明授权

US5638794A Servo valve type timer for fuel injection pump 失效
标题翻译：伺服阀式定时器，用于燃油喷射泵
公开(公告)号：US5638794A
公开(公告)日：1997-06-17
申请号：US492164
申请日：1995-06-19
申请人： Ken-ichi Kubo , Jun Matsubara
发明人： Ken-ichi Kubo , Jun Matsubara
IPC分类号： F02D1/18 , F02M41/12 , F02M41/14 , F02M37/04
CPC分类号： F02M41/128 , F02M41/1416
摘要： A servo valve type timer for controlling a fuel injection timing on the basis of the difference in pressure between a high-pressure chamber and a low-pressure chamber, including a timer piston for adjustment of a fuel injection timing which is disposed between the high-pressure chamber and the low-pressure chamber so as to be slidable between the high-pressure chamber and the low-pressure chamber and is operated in accordance with a fuel pressure introduced into the high-pressure chamber and/or the low-pressure chamber, a servo valve for controlling the operation of the timer piston, and a pressure control member for adjusting the fuel pressure of the low-pressure chamber.
摘要翻译：一种用于基于高压室和低压室之间的压力差控制燃料喷射正时的伺服阀式定时器，包括用于调节燃料喷射正时的定时器活塞，压力室和低压室，以便能够在高压室和低压室之间滑动，并且根据引入高压室和/或低压室的燃料压力进行操作，用于控制定时器活塞的操作的伺服阀，以及用于调节低压室的燃料压力的压力控制构件。

7. 发明授权

US08349840B2 Piperazine-substituted benzothiophenes for treatment of mental disorders 有权
公开(公告)号：US08349840B2
公开(公告)日：2013-01-08
申请号：US12970690
申请日：2010-12-16
申请人： Hiroshi Yamashita , Nobuaki Ito , Shin Miyamura , Kunio Oshima , Jun Matsubara , Hideaki Kuroda , Haruka Takahashi , Satoshi Shimizu , Tatsuyoshi Tanaka
发明人： Hiroshi Yamashita , Nobuaki Ito , Shin Miyamura , Kunio Oshima , Jun Matsubara , Hideaki Kuroda , Haruka Takahashi , Satoshi Shimizu , Tatsuyoshi Tanaka
IPC分类号： A61K31/496
CPC分类号： A61K31/496 , C07D405/12 , C07D409/12 , C07D409/14
摘要： The present invention provides a heterocyclic compound represented by the general formula (1): The compound of the present invention has a wide treatment spectrum for mental disorders including central nervous system disorders, no side effects and high safety.

8. 发明授权

US5148295A Information processing apparatus 失效
标题翻译：信息处理装置
公开(公告)号：US5148295A
公开(公告)日：1992-09-15
申请号：US733964
申请日：1991-07-22
申请人： Jun Matsubara
发明人： Jun Matsubara
IPC分类号： H04N1/00 , H04N1/04
CPC分类号： H04N1/00405 , H04N1/00384 , H04N1/00411 , H04N1/00413 , H04N1/0049 , H04N1/0402 , H04N1/0405 , H04N1/0417
摘要： An information processing apparatus including an image scanner, on which original documents with any vertical or horizontal format are placed, for optically scanning the images of the original documents to generate output image information and format setting keys for designating the format of the original documents and generating information concerning the format of the original documents. The apparatus further includes a first memory for storing the information concerning the format of the original documents generated by the format setting keys and for outputting the information concerning the format; an enlargement/reduction unit for changing the size of the image information of a whole vertical original document and a whole horizontal original document output from the image scanner with the same magnification and for outputting the changed image information; a second memory for storing the image information output from the enlargement/reduction unit in accordance with the information concerning the format of the original documents output from the first memory and for outputting the image information; and a display unit having a square screen for displaying the image information from the second memory on the square screen.
摘要翻译：一种信息处理设备，包括：图像扫描器，其上放置有任何垂直或水平格式的原始文档，用于光学扫描原始文档的图像，以产生输出图像信息和格式设置键，用于指定原始文档的格式并产生有关原始文件格式的信息。该装置还包括第一存储器，用于存储关于由格式设置键生成的原始文档的格式的信息，并且用于输出关于格式的信息; 放大/缩小单元，用于改变整个垂直原稿的图像信息的尺寸和以相同的倍率从图像扫描仪输出的整个水平原稿，并输出改变的图像信息; 第二存储器，用于根据关于从第一存储器输出的原始文档的格式的信息存储从放大/缩小单元输出的图像信息，并输出图像信息; 以及显示单元，具有用于在平方屏幕上显示来自第二存储器的图像信息的方形屏幕。

9. 发明授权

US08598162B2 Derivatives of 4-piperazin-1-yl-4-benzo[B]thiophene suitable for the treatment of CNS disorders 失效
标题翻译：适用于治疗CNS疾病的4-哌嗪-1-基-4-苯并[b]噻吩的衍生物
公开(公告)号：US08598162B2
公开(公告)日：2013-12-03
申请号：US13270544
申请日：2011-10-11
申请人： Hiroshi Yamashita , Hideaki Kuroda , Nobuaki Ito , Jun Matsubara , Yohji Sakurai
发明人： Hiroshi Yamashita , Hideaki Kuroda , Nobuaki Ito , Jun Matsubara , Yohji Sakurai
IPC分类号： A61K31/496 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/541 , C07D409/12 , C07D409/14 , C07D417/14
CPC分类号： C07D409/12 , C07D333/54 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D487/08 , C07D491/113
摘要： A heterocyclic compound or a salt thereof represented by the formula (1): where R2 represents a hydrogen atom or a lower alkyl group; A represents a lower alkylene group or lower alkenylene group; and R1 represents an aromatic group or a heterocyclic group. The compound of the present invention has a wide treatment spectrum for mental disorders including central nervous system disorders, no side effects and high safety.
摘要翻译：由式（1）表示的杂环化合物或其盐：其中R 2表示氢原子或低级烷基; A表示低级亚烷基或低级亚烯基; R1表示芳基或杂环基。本发明的化合物具有广泛的精神障碍治疗范围，包括中枢神经系统疾病，无副作用和高安全性。

10. 发明授权

US07888362B2 Piperazine-substituted benzothiophenes for treatment of mental disorders 有权
标题翻译：哌嗪取代的苯并噻吩用于治疗精神障碍
公开(公告)号：US07888362B2
公开(公告)日：2011-02-15
申请号：US11659005
申请日：2006-04-12
申请人： Hiroshi Yamashita , Nobuaki Ito , Shin Miyamura , Kunio Oshima , Jun Matsubara , Hideaki Kuroda , Haruka Takahashi , Satoshi Shimizu , Tatsuyoshi Tanaka
发明人： Hiroshi Yamashita , Nobuaki Ito , Shin Miyamura , Kunio Oshima , Jun Matsubara , Hideaki Kuroda , Haruka Takahashi , Satoshi Shimizu , Tatsuyoshi Tanaka
IPC分类号： A61K31/496 , C07D409/12
CPC分类号： C07D409/12 , C07D409/14
摘要： The present invention provides a heterocyclic compound represented by the general formula (1): The compound of the present invention has a wide treatment spectrum for mental disorders including central nervous system disorders, no side effects and high safety.
摘要翻译：本发明提供由通式（1）表示的杂环化合物：本发明化合物具有广泛的精神障碍治疗谱，包括中枢神经系统疾病，副作用高，安全性高。

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